CD81 is required for hepatitis C virus glycoprotein-mediated viral infection.

abstract：:Transgenic mice containing the complete human immunodeficiency virus (HIV) coding sequences fused to the mouse mammary tumor virus long terminal repeat were generated. They were found to produce high levels of authentic gag and env HIV proteins in several tissues known to support mouse mammary tumor virus-driven trans...

journal_title：Journal of virology

authors： Jolicoeur P,Laperrière A,Beaulieu N

更新日期：1992-06-01 00:00:00

abstract：:Dengue virus (DENV) is a mosquito-borne flavivirus responsible for dengue disease, a major human health concern for which no specific therapies are available. Like other viruses, DENV relies heavily on the host cellular machinery for productive infection. In this study, we performed a genome-wide CRISPR-Cas9 screen us...

journal_title：Journal of virology

authors： Labeau A,Simon-Loriere E,Hafirassou ML,Bonnet-Madin L,Tessier S,Zamborlini A,Dupré T,Seta N,Schwartz O,Chaix ML,Delaugerre C,Amara A,Meertens L

更新日期：2020-03-17 00:00:00

abstract：UNLABELLED:Arthritogenic alphaviruses such as Ross River virus (RRV) and chikungunya virus (CHIKV) cause large-scale epidemics of severe musculoskeletal disease and have been progressively expanding their global distribution. Since its introduction in July 2014, CHIKV now circulates in the United States. The hallmark o...

journal_title：Journal of virology

authors： Herrero LJ,Foo SS,Sheng KC,Chen W,Forwood MR,Bucala R,Mahalingam S

更新日期：2015-08-01 00:00:00

abstract：:The interaction of the human immunodeficiency virus (HIV) Gag protein with the plasma membrane of a cell is a critical event in the assembly of HIV particles. The matrix protein region (MA) of HIV type 1 (HIV-1) Pr55Gag has previously been demonstrated to confer membrane-binding properties on the precursor polyprotein...

journal_title：Journal of virology

authors： Spearman P,Horton R,Ratner L,Kuli-Zade I

更新日期：1997-09-01 00:00:00

abstract：:Mother-to-child transmission can occur in utero, mainly intrapartum and postpartum in case of breastfeeding. In utero transmission is highly restricted and results in selection of viral variant from the mother to the child. We have developed an in vitro system that mimics the interaction between viruses, infected cell...

journal_title：Journal of virology

authors： Lagaye S,Derrien M,Menu E,Coïto C,Tresoldi E,Mauclère P,Scarlatti G,Chaouat G,Barré-Sinoussi F,Bomsel M,European Network for the Study of In Utero Transmission of HIV-1.

更新日期：2001-05-01 00:00:00

abstract：:Recent studies of varicella-zoster virus (VZV) DNA sequence variation, involving large numbers of globally distributed clinical isolates, suggest that this virus has diverged into at least three distinct genotypes designated European (E), Japanese (J), and mosaic (M). In the present study, we determined and analyzed t...

journal_title：Journal of virology

authors： Norberg P,Liljeqvist JA,Bergström T,Sammons S,Schmid DS,Loparev VN

更新日期：2006-10-01 00:00:00

abstract：:Inhibition of hepatitis B virus (HBV) replication and viral clearance from an infected host requires both the innate and adaptive immune responses. Expression of interferon (IFN)-inducible proteasome catalytic and regulatory subunits correlates with the IFN-alpha/beta- and IFN-gamma-mediated noncytopathic inhibition o...

journal_title：Journal of virology

authors： Robek MD,Garcia ML,Boyd BS,Chisari FV

更新日期：2007-01-01 00:00:00

abstract：:China is facing a rapid upsurge in cases of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) infection due to large numbers of paid blood donors (PBD), injection drug users (IDU), and sexual partners of infected individuals. In this report, a total of 236 HIV-1-positive blood samples were collec...

journal_title：Journal of virology

authors： Zhang L,Chen Z,Cao Y,Yu J,Li G,Yu W,Yin N,Mei S,Li L,Balfe P,He T,Ba L,Zhang F,Lin HH,Yuen MF,Lai CL,Ho DD

更新日期：2004-12-01 00:00:00

abstract：:We generated Chinese hamster ovary cell lines that stably express wild-type, secreted, and glycosylphosphatidylinositol (GPI)-anchored envelope glycoprotein of human immunodeficiency virus type 1 (HIV-1). The cells expressing wild-type Env (WT cells) express both the precursor gp160 and the mature gp120/gp41 and readi...

journal_title：Journal of virology

authors： Weiss CD,White JM

更新日期：1993-12-01 00:00:00

abstract：:MxA is an abundant and ubiquitous cytoplasmic protein induced by alpha/beta interferon in human cells. Upon full induction, it can constitute 0.5 to 1% of cytosolic proteins. MxA can bind elements of the cytoskeleton, such as actin and tubulins, and several larger cellular proteins. However, these protein-protein inte...

journal_title：Journal of virology

authors： Horisberger MA

更新日期：1992-08-01 00:00:00

abstract：:The hepatitis B virus (HBV) core promoter regulates the transcription of two related RNA products named precore RNA and core RNA. Previous studies indicate that a double-nucleotide mutation that occurs frequently during chronic HBV infection converts a nuclear receptor binding site in the core promoter to the binding ...

journal_title：Journal of virology

authors： Li J,Xu Z,Zheng Y,Johnson DL,Ou JH

更新日期：2002-06-01 00:00:00

abstract：:Hepatitis C virus (HCV) is a single-stranded positive-sense RNA hepatotropic virus. Despite cellular defenses, HCV is able to replicate in hepatocytes and to establish a chronic infection that could lead to severe complications and hepatocellular carcinoma. An important player in subverting the host response to HCV in...

journal_title：Journal of virology

authors： Çevik RE,Cesarec M,Da Silva Filipe A,Licastro D,McLauchlan J,Marcello A

更新日期：2017-08-24 00:00:00

abstract：:Valproic acid (VPA) is a short-chain fatty acid commonly used for treatment of neurological disorders. As VPA can interfere with cellular lipid metabolism, its effect on the infection of cultured cells by viruses of seven viral families relevant to human and animal health, including eight enveloped and four nonenvelop...

journal_title：Journal of virology

authors： Vázquez-Calvo A,Saiz JC,Sobrino F,Martín-Acebes MA

更新日期：2011-02-01 00:00:00

abstract：:The expression of interleukin-2 (IL-2) has been implicated in the modulation of the outcome of ocular infection with herpes simplex virus type 1 (HSV-1); however, its effects remain controversial. To clarify the role of IL-2, we constructed a recombinant HSV-1 (HSV-IL-2) that expresses two copies of the murine IL-2 ge...

journal_title：Journal of virology

authors： Ghiasi H,Osorio Y,Perng GC,Nesburn AB,Wechsler SL

更新日期：2002-09-01 00:00:00

abstract：:Although adeno-associated virus type 2 (AAV) has gained attention as a potentially useful vector for human gene therapy, the transduction efficiencies of AAV vectors vary greatly in different cells and tissues in vitro and in vivo. We have documented that a cellular tyrosine phosphoprotein, designated the single-stran...

journal_title：Journal of virology

authors： Qing K,Hansen J,Weigel-Kelley KA,Tan M,Zhou S,Srivastava A

更新日期：2001-10-01 00:00:00

abstract：:One unique feature of the shrimp white spot syndrome virus (WSSV) genome is the presence of a giant open reading frame (ORF) of 18,234 nucleotides that encodes a long polypeptide of 6,077 amino acids with a hitherto unknown function. In the present study, by applying proteomic methodology to analyze the sodium dodecyl...

journal_title：Journal of virology

authors： Leu JH,Tsai JM,Wang HC,Wang AH,Wang CH,Kou GH,Lo CF

更新日期：2005-01-01 00:00:00

abstract：:The entry mechanism of hepatitis B virus (HBV) has not been defined, and this impedes development of antiviral therapies aimed at an early step in the viral life cycle. HBV infection has both host and tissue specificities. For the related duck hepatitis B virus (DHBV), duck carboxypeptidase D (DCPD) has been proposed ...

journal_title：Journal of virology

authors： Tong Y,Tong S,Zhao X,Wang J,Jun J,Park J,Wands J,Li J

更新日期：2010-05-01 00:00:00

abstract：:During paramyxovirus entry into a host cell, receptor engagement by a specialized binding protein triggers conformational changes in the adjacent fusion protein (F), leading to fusion between the viral and cell membranes. According to the existing paradigm of paramyxovirus membrane fusion, the initial activation of F ...

journal_title：Journal of virology

authors： Porotto M,Devito I,Palmer SG,Jurgens EM,Yee JL,Yokoyama CC,Pessi A,Moscona A

更新日期：2011-12-01 00:00:00

abstract：:Worldwide amphibian population declines have been ascribed to global warming, increasing pollution levels, and other factors directly related to human activities. These factors may additionally be favoring the emergence of novel pathogens. In this report, we have determined the complete genome sequence of the emerging...

journal_title：Journal of virology

authors： Mavian C,López-Bueno A,Balseiro A,Casais R,Alcamí A,Alejo A

更新日期：2012-04-01 00:00:00

abstract：:The human herpes simplex virus (HSV) protein VP16 induces formation of a transcriptional regulatory complex with two cellular factors-the POU homeodomain transcription factor Oct-1 and the cell proliferation factor HCF-1-to activate viral immediate-early-gene transcription. Although the cellular role of Oct-1 in trans...

journal_title：Journal of virology

authors： Lee S,Herr W

更新日期：2001-12-01 00:00:00

abstract：:The tsB5 mutant of herpes simplex virus type 1 (HSV-1) strain HFEM was shown previously to be temperature sensitive for accumulation of the mature form of glycoprotein gB, for production or activity of a factor required in virus-induced cell fusion, and for production of virions with normal levels of infectivity. In a...

journal_title：Journal of virology

authors： Haffey ML,Spear PG

更新日期：1980-07-01 00:00:00

abstract：:The U(S)3 open reading frame of herpes simplex virus 1 (HSV-1) was reported to encode two mRNAs each directing the synthesis of the same protein. We report that the U(S)3 gene encodes two proteins. The predominant U(S)3 protein is made in wild-type HSV-1-infected cells. The truncated mRNA and a truncated protein desig...

journal_title：Journal of virology

authors： Poon AP,Roizman B

更新日期：2005-07-01 00:00:00

abstract：:The sodium dodecyl sulfate (SDS) complex of the major glycoprotein of avian myeloblastosis virus exhibited an anomalously low free electrophoretic mobility compared with those of non-glycosylated protein standards. The apparent molecular weight of the glycoprotein calculated from the relation between log molecular wei...

journal_title：Journal of virology

authors： Marciani DJ,Papamatheakis JD

更新日期：1978-06-01 00:00:00

abstract：:DNA sequences which have structural features suggestive of their functioning as an origin of lytic-phase DNA replication were previously identified in both human herpesvirus 6B strain Z29 [HHV-6B (Z29)] and in HHV-6A (U1102). Plasmid constructs containing the putative HHV-6B (Z29) oriLyt element were replicated after ...

journal_title：Journal of virology

authors： Dewhurst S,Dollard SC,Pellett PE,Dambaugh TR

更新日期：1993-12-01 00:00:00

abstract：:DNA vaccines have recently emerged at the forefront of approaches to harness the immune system in the prevention and treatment of viral infections, as well as the prevention and treatment of cancers. However, these vaccines suffer from limited efficacy since they often fail to produce significant antigen-specific CD8(...

journal_title：Journal of virology

authors： Mao CP,Hung CF,Kang TH,He L,Tsai YC,Wu CY,Wu TC

更新日期：2010-03-01 00:00:00

abstract：:The region of the UL component of the herpes simplex virus type 1 genome between nucleotides 17,793 and 25,150 includes three open reading frames that code for the protein products of the UL8, UL9, and UL10 genes (D.J. McGeogh, M.A. Dalrymple, A.J. Davison, A. Dolan, M.C. Frame, D. McNab, L.J. Perry, J.E. Scott, and P...

journal_title：Journal of virology

authors： Baradaran K,Dabrowski CE,Schaffer PA

更新日期：1994-07-01 00:00:00

abstract：:Human adenovirus 41 (HAdV-41) causes acute gastroenteritis in young children. The main characteristics of HAdV-41 infection are diarrhea and vomiting. Nevertheless, the precise mechanism of HAdV-41-induced diarrhea is unknown, as a suitable small-animal model has not been described. In this study, we used the human mi...

journal_title：Journal of virology

authors： Westerberg S,Hagbom M,Rajan A,Loitto V,Persson BD,Allard A,Nordgren J,Sharma S,Magnusson KE,Arnberg N,Svensson L

更新日期：2018-03-14 00:00:00

abstract：:A detailed kinetic and quantitative analysis of the early and late biosynthetic events undergone by the human immunodeficiency virus type 1 envelope protein expressed by a recombinant vaccinia virus was performed. Early folding events that occurred in the endoplasmic reticulum included disulfide bond formation (t1/2 a...

journal_title：Journal of virology

authors： Earl PL,Moss B,Doms RW

更新日期：1991-04-01 00:00:00

abstract：:Influenza A viruses of the H9N2 subtype are endemic in poultry in many Eurasian countries and have occasionally caused clinical respiratory diseases in humans. While some avian H9N2 viruses have glutamine (Q) at amino acid position 226 of the hemagglutinin (HA) receptor-binding site, an increasing number of isolates h...

journal_title：Journal of virology

authors： Wan H,Perez DR

更新日期：2007-05-01 00:00:00

abstract：:The genome sequence of a hypervirulent novirhabdovirus, viral hemorrhagic septicemia virus (VHSV) French strain 23-75, was determined. Compared to the genome of the prototype Fil3 strain, a number of substitutions, deletions, and insertions were observed. Following the establishment of a plasmid-based minigenome repli...

journal_title：Journal of virology

authors： Biacchesi S,Lamoureux A,Mérour E,Bernard J,Brémont M

更新日期：2010-10-01 00:00:00