Acute rejection after renal transplantation is reduced by approximately 50% by prior therapeutic blood transfusions, even in tacrolimus-treated patients.

abstract：BACKGROUND:Globalization and migration patterns have increased the number of donors from countries with high incidence rates of tuberculosis (TB) in low incidence countries, with the subsequent increase in risk of TB transmission to the recipients. METHODS:Retrospective cohort study, including all actual deceased dono...

journal_title：Transplantation

authors： Coll E,Torre-Cisneros J,Calvo R,Garrido G,Matesanz R

更新日期：2013-07-27 00:00:00

abstract：:In a prospective longitudinal study, detection of cytomegalovirus (CMV) DNA in plasma (plasma polymerase chain reaction [PCR]) was compared with PCR of CMV DNA in peripheral blood leukocytes (PBL PCR), the CMV pp65 antigenemia assay, and viral cultures from blood, urine, and throat of 29 patients, 14 of whom received ...

journal_title：Transplantation

authors： Boeckh M,Gallez-Hawkins GM,Myerson D,Zaia JA,Bowden RA

更新日期：1997-07-15 00:00:00

abstract：:Living-donor liver transplantation has provided a solution to the severe lack of cadaveric grafts for the replacement of livers afflicted with end-stage cirrhosis, fulminant disease, or inborn errors of metabolism. The pioneering experience in Japan in the early 1990s helped open wide the avenues of a new branch of sc...

journal_title：Transplantation

authors： Chen CL,Fan ST,Lee SG,Makuuchi M,Tanaka K

更新日期：2003-02-15 00:00:00

abstract：BACKGROUND:In December 2018, United Network for Organ Sharing approved an allocation scheme based on recipients' geographic distance from a deceased donor (acuity circles [ACs]). Previous analyses suggested that ACs would reduce waitlist mortality overall, but their impact on pediatric subgroups was not considered. ME...

journal_title：Transplantation

authors： Mogul DB,Perito ER,Wood N,Mazariegos GV,VanDerwerken D,Ibrahim SH,Mohammad S,Valentino PL,Gentry S,Hsu E

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:This 36-month, randomized, parallel-group study compared safety and efficacy of two doses of everolimus with mycophenolate mofetil (MMF) in de novo renal-transplant recipients. METHODS:Renal-allograft recipients received 1.5 mg/day or 3 mg/day of everolimus or 2 g/day of MMF, plus full-dose cyclosporine (Cs...

journal_title：Transplantation

authors： Lorber MI,Mulgaonkar S,Butt KM,Elkhammas E,Mendez R,Rajagopalan PR,Kahan B,Sollinger H,Li Y,Cretin N,Tedesco H,B251 Study Group.

更新日期：2005-07-27 00:00:00

abstract：:In three patients with end-stage renal failure due to primary hyperoxaluria type 1, successful combined liver-kidney transplantation enabled us to assess the insoluble oxalate pool, which was compared with the histopathological changes observed in iliac crest biopsy specimens. Good correlation was observed between the...

journal_title：Transplantation

authors： Toussaint C,Vienne A,De Pauw L,Gelin M,Janssen F,Hall M,Schurmans T,Pasteels JL

更新日期：1995-06-27 00:00:00

abstract：BACKGROUND:The pathogenesis of acute pulmonary xenograft injury has not yet been determined. The present study evaluates the role of complement in mediating pulmonary xenograft dysfunction by using cobra venom factor (CVF) to deplete recipient complement and transgenic swine, which express human regulators of complemen...

journal_title：Transplantation

authors： Yeatman M,Daggett CW,Parker W,Byrne GW,Logan JS,Platt JL,Davis RD

更新日期：1998-04-27 00:00:00

abstract：BACKGROUND:A regimen consisting of antilymphocyte serum (ALS), sirolimus, and donor bone-marrow-cell (BMC) infusion induces indefinite skin allograft survival across fully mismatched mouse strain combinations. We investigated the role of chimerism in this transplantation tolerance model. MATERIALS:B10.A (H-2a) mice we...

journal_title：Transplantation

authors： Kanamoto A,Monaco AP,Maki T

更新日期：2004-09-27 00:00:00

abstract：:The rat aortic transplant model was modified to investigate whether the vascular wall changes on chronic rejection are reversible. DA (RT1a) aortas were first transplanted to WF (RT1a) recipients. The first transplantation was accompanied, as described earlier, by an increase in intimal cellularity and thickness and t...

journal_title：Transplantation

authors： Mennander A,Häyry P

更新日期：1996-08-27 00:00:00

abstract：BACKGROUND:Hemodynamic monitoring using transesophageal echocardiography (TEE) in patients with signs of portal hypertension undergoing orthotopic liver transplantation (OLT) carries potential risk of esophageal and gastric variceal hemorrhage. The aim of our retrospective analysis was to evaluate the safety of intraop...

journal_title：Transplantation

authors： Burger-Klepp U,Karatosic R,Thum M,Schwarzer R,Fuhrmann V,Hetz H,Bacher A,Berlakovich G,Krenn CG,Faybik P

更新日期：2012-07-27 00:00:00

abstract：BACKGROUND:One method of countering chronic lung donor shortages is the practice of donation after cardiac death (DCD). However, this technique inevitably leads to pulmonary dysfunction related to warm ischemia. One promising method of alleviating this problem is ventilation. However, it can rarely be initiated from th...

journal_title：Transplantation

authors： Sakamoto J,Chen F,Yamada T,Nakajima D,Ohsumi A,Kikuchi R,Zhao X,Fujinaga T,Shoji T,Sakai H,Bando T,Date H

更新日期：2011-10-27 00:00:00

abstract：BACKGROUND:The rate of acute rejection (AR) has decreased significantly, but whether this is associated with improvement in long-term graft survival is controversial. METHODS:We analyzed 1445 consecutive adult deceased donor kidney transplant recipients from 1985 to 2005, over two periods (1985-1995 vs. 1996-2005) to ...

journal_title：Transplantation

authors： Sola E,Gonzalez-Molina M,Cabello M,Burgos D,Ramos J,Gutierrez C,Lopez V,Soler J,de la Vega E,Hernandez D

更新日期：2010-03-27 00:00:00

abstract：BACKGROUND:Chronic cyclosporine (CsA) nephropathy, which has been unequivocally documented in recipients of heart, heart-lung, liver, or bone marrow transplants, as well as in nontransplant situations, usually results in a progressive deterioration of renal function. In this study, we assessed the potential reversibili...

journal_title：Transplantation

authors： Mourad G,Vela C,Ribstein J,Mimran A

更新日期：1998-03-15 00:00:00

abstract：:Hepatic artery thrombosis is a continuing source of morbidity and mortality following orthotopic liver transplantation. The cornerstone of therapy has been urgent retransplantation that is limited by organ availability. For this reason we developed a policy of urgent revascularization for allograft rescue. Hepatic art...

journal_title：Transplantation

authors： Langnas AN,Marujo W,Stratta RJ,Wood RP,Li SJ,Shaw BW

更新日期：1991-01-01 00:00:00

abstract：:Recent suggestions that the rat prostate is an alymphatic, immunologically privileged site stimulated further investigation of its status using a variety of techniques. Fixation of certain organs by vascular perfusion of glutaraldehyde followed by plastic embedding avoids the distortion and stromal reorganization that...

journal_title：Transplantation

authors： Neaves WB,Billingham RE

更新日期：1979-02-01 00:00:00

abstract：:LEW rats (RT1l) that are lethally irradiated and repopulated with syngenic bone marrow accept WF (RT1u) cardiac allografts. If bone marrow repopulation is delayed for two days after irradiation and operation, grafts containing passenger leukocytes (nonperfused grafts) are generally rejected, but perfused grafts, which...

journal_title：Transplantation

authors： Hartnett LC,Dittmer JE,Schwadron RB

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Vaccine-preventable viral infections are associated with increased risk of morbidity and mortality in immunocompromised patients. Current guidelines recommend routine screening and vaccination of all patients before solid organ transplantation. We studied rates of immunity against vaccine-preventable viruses...

journal_title：Transplantation

authors： Gardiner A,Liu K,Bonnichsen M,Joshi V,Davis RJ,Strasser SI

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Membrane CD30 is an important costimulatory molecule for activated T lymphocytes, and serum level of soluble CD30 (sCD30) is considered a marker for predicting outcome in kidney transplantation. METHODS:We investigated the kinetics of CD30 expression on CD4 and CD8 T-cell populations and the source of sCD30...

journal_title：Transplantation

authors： Velásquez SY,García LF,Opelz G,Alvarez CM,Süsal C

更新日期：2013-07-27 00:00:00

abstract：:In the USA approximately 10% of candidates for renal transplantation have serum antibodies to hepatitis C (HCV). To assess the possible impact of HCV infection on early posttransplant events we assessed allograft complications during the first 6 months following renal transplantation in three groups of adult renal all...

journal_title：Transplantation

authors： Cosio FG,Sedmak DD,Henry ML,Al Haddad C,Falkenhain ME,Elkhammas EA,Davies EA,Bumgardner GL,Ferguson RM

更新日期：1996-10-27 00:00:00

abstract：BACKGROUND:Recent data show the efficacy of embryonic stem cells (ESC) to engraft in allogeneic recipients without host pretreatment. This property is due to their low expression of major histocompatibility complex (MHC) class I antigens and lack of MHC class II expression. Here, we tested the hypothesis that the const...

journal_title：Transplantation

authors： Fabricius D,Bonde S,Zavazava N

更新日期：2005-05-15 00:00:00

abstract：:Among the first 52 recipients of primary liver allografts with follow-up of 2 weeks or greater, 6 patients had biopsy-confirmed vanishing bile duct syndrome (VBDS) and required retransplantation. Five of these six patients had positive lymphocyte crossmatches. Of the 46 remaining liver transplant recipients, 11 had po...

journal_title：Transplantation

authors： Batts KP,Moore SB,Perkins JD,Wiesner RH,Grambsch PM,Krom RA

更新日期：1988-02-01 00:00:00

abstract：:Preoperative portal venous injection of donor lymphocytes has been shown to extend allograft survival in inbred animals. However, the effect of perioperative injection in a large animal model has not been carefully studied. We examined the effect of perioperative (day 0) donor spleen cell administration in a canine ki...

journal_title：Transplantation

authors： Tsuji T,Tashiro S,Tanabe D,Sawada T,Inoue K,Kawamoto S,Kamimoto Y,Miyauchi Y

更新日期：1994-10-27 00:00:00

abstract：BACKGROUND:Primary hyperoxaluria type-1 (PH1) is an autosomal recessive disease characterized by excessive oxalate production by hepatocytes caused by the deficiency of peroxisomal alanine-glyoxylate aminotransferase (AGT) activity. Persistent hyperoxaluria causes nephrocalcinosis and urolithiasis, leading to renal fai...

journal_title：Transplantation

authors： Jiang J,Salido EC,Guha C,Wang X,Moitra R,Liu L,Roy-Chowdhury J,Roy-Chowdhury N

更新日期：2008-05-15 00:00:00

abstract：BACKGROUND:The need to find a safe, effective liver support system for patients with fulminant hepatic failure (FHF) continues to be unmet. A system using immortalized human hepatocytes was originally developed in the early 1990s. A modified version of the initial extracorporeal liver-assist device (ELAD) was recently ...

journal_title：Transplantation

authors： Millis JM,Cronin DC,Johnson R,Conjeevaram H,Conlin C,Trevino S,Maguire P

更新日期：2002-12-27 00:00:00

abstract：:To investigate the clinical manifestations of Aspergillus infections in lung transplant recipients, we reviewed the mycology and autopsy reports of all double (DLT=93) and single (SLT=48) lung transplant recipients from November 1983 to May 1993. Positive Aspergillus cultures were identified in 22% of the recipients (...

journal_title：Transplantation

authors： Westney GE,Kesten S,De Hoyos A,Chapparro C,Winton T,Maurer JR

更新日期：1996-03-27 00:00:00

abstract：BACKGROUND:Antibody-mediated rejection (AMR) remains associated with reduced kidney graft survival and no clear prognostic marker is available. METHODS:We investigated whether donor-specific antibodies (DSA) ability to bind C1q in comparison with AMR C4d status, both indirect signs of complement activation, improve ri...

journal_title：Transplantation

authors： Malheiro J,Santos S,Tafulo S,Dias L,Martins S,Fonseca I,Almeida M,Pedroso S,Beirão I,Castro-Henriques A,Cabrita A

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Functionally relevant polymorphisms in genes of the Th1 and Th2-inflammatory pathway influence the susceptibility to acute rejection (AR), chronic allograft nephropathy (CAN), and subclinical rejection (SR) as well as graft survival after renal transplantation. Because these findings have not been validated,...

journal_title：Transplantation

authors： Brabcova I,Petrasek J,Hribova P,Hyklova K,Bartosova K,Lacha J,Viklický O

更新日期：2007-10-27 00:00:00

abstract：BACKGROUND:Donor organ shortage represents a major problem in lung transplantation. Donation after cardiac death could help to expand the pool of organs, but the additional period of warm ischemia after cardiac arrest aggravates primary graft dysfunction. The pulmonary endothelium of the graft constitutes an important ...

journal_title：Transplantation

authors： Preissler G,Loehe F,Huff IV,Ebersberger U,Shuvaev VV,Bittmann I,Hermanns I,Kirkpatrick JC,Fischer K,Eichhorn ME,Winter H,Jauch KW,Albelda SM,Muzykantov VR,Wiewrodt R

更新日期：2011-08-27 00:00:00

abstract：:Neither the presence nor the specific role of secretory cytokines in in vivo allograft rejection has been extensively studied. We quantitated the levels of colony-stimulating factors, tumor necrosis factor, and interleukin 1 within the rejecting allograft. BALB/c (H-2d) mice were implanted with polyurethane sponges co...

journal_title：Transplantation

authors： Ford HR,Hoffman RA,Wing EJ,Magee DM,McIntyre LA,Simmons RL

更新日期：1990-09-01 00:00:00

abstract：:To determine the impact of different flush and reperfusion techniques on postreperfusion syndrome (PRS) and postoperative graft function, 100 transplants were randomly assigned into four groups as follows: group 1 (n=31), portal vein flush, no vena caval venting; group 2 (n=21), hepatic arterial flush, no vena caval v...

journal_title：Transplantation

authors： Millis JM,Melinek J,Csete M,Imagawa DK,Olthoff KM,Neelankanta G,Braunfeld MY,Sopher MJ,Chan SM,Pregler JL,Yersiz H,Busuttil AA,Shackleton CR,Shaked A,Busuttil RW

更新日期：1997-02-15 00:00:00