Abstract:
:Cerebral cavernous malformations (CCM) are CNS vascular anomalies associated with seizures, headaches, and hemorrhagic strokes. The CCM1 gene was screened in 35 sporadic cases with either single or multiple CCM. It was found that 29% of the individuals with multiple CCM have a CCM1 mutation, whereas cases with only one malformation have none. Sporadic cases with multiple malformations warrant the same approach as individuals who have a familial history of CCM.
journal_name
Neurologyjournal_title
Neurologyauthors
Verlaan DJ,Laurent SB,Sure U,Bertalanffy H,Andermann E,Andermann F,Rouleau GA,Siegel AMdoi
10.1212/01.wnl.0000118299.55857.bbsubject
Has Abstractpub_date
2004-04-13 00:00:00pages
1213-5issue
7eissn
0028-3878issn
1526-632Xjournal_volume
62pub_type
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