Effect of tryptophan depletion on symptoms of motion sickness in migraineurs.

Abstract:

:Seven hours after 39 migraineurs and 37 controls consumed an amino acid drink that contained or omitted l-tryptophan (thereby reducing brain serotonin synthesis), motion sickness was provoked by the visual illusion of movement. Tryptophan depletion boosted dizziness, nausea, and the illusion of movement in controls to levels that approached those of migraineurs. Thus, reduced brain serotonin activity may promote vestibuloocular disturbances during motion sickness and attacks of migraine.

journal_name

Neurology

journal_title

Neurology

authors

Drummond PD

doi

10.1212/01.wnl.0000172339.15577.a6

subject

Has Abstract

pub_date

2005-08-23 00:00:00

pages

620-2

issue

4

eissn

0028-3878

issn

1526-632X

pii

65/4/620

journal_volume

65

pub_type

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