Abstract:
:The purpose of this study was to examine the influence of exercise on the serum concentrations of intact parathyroid hormone (PTH). Serum PTH and plasma lactate were measured in 15 well-trained men, 9 long-distance runners and 6 fire-fighters, during two running exercises. Test one consisted of 40-minute treadmill running with a step-wise increased load and test two consisted of 50-minute treadmill running with a constant velocity. When the load was step-wise increased, the PTH concentrations increased moderately at the slower running paces but reached a final value that was about 50% higher than the starting value. This rise occurred despite a concomitant increase of total serum calcium from 2.38 +/- 0.06 to 2.49 +/- 0.05 mmol/liter (P < 0.01). During the constant running exercise, the long-distance runners, but not the fire-fighters, displayed a significant increase in PTH concentrations although the rise in total serum calcium was similar in both groups. There was a weak correlation between the changes in PTH and lactate in both exercises. The findings demonstrate that both high and low intensity exercise enhance release of PTH in long-distance runners through a mechanism that does not involve serum calcium. This relationship might be of importance for bone mass in men performing long-distance training.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Salvesen H,Johansson AG,Foxdal P,Wide L,Piehl-Aulin K,Ljunghall Sdoi
10.1007/BF00295947subject
Has Abstractpub_date
1994-04-01 00:00:00pages
256-61issue
4eissn
0171-967Xissn
1432-0827journal_volume
54pub_type
杂志文章abstract::The aim of this study was to analyze the efficacy of using rhBMP-2 (recombinant human morphogenetic protein-2) in the treatment of patients with cleft lip and palate defects (CLPD). Seven databases were screened: PubMed (Medline), Lilacs, Ibecs, Web of Science, BBO, Scopus, and The Cochrane Library. Clinical trials th...
journal_title:Calcified tissue international
pub_type: 杂志文章,meta分析
doi:10.1007/s00223-018-0486-1
更新日期:2019-02-01 00:00:00
abstract::The effect of teriparatide treatment on microdamage accumulation has yet to be examined in animal studies. The purpose of this study was to investigate the effect of once-weekly teriparatide treatment on bone microdamage accumulation and the relationship between microdamage parameters and bone mass, architecture, turn...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-018-0500-7
更新日期:2019-04-01 00:00:00
abstract::This study aims to test the hypothesis that noninvasive bone mass measurements can be used to predict bone strength in a piglet model. Dual energy X-ray absorptiometry measurements of bone mineral content (BMC), bone mineral density (BMD), and bone area (BA) were obtained from four sets of bones (left and right humeri...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002230010006
更新日期:2001-04-01 00:00:00
abstract::A guidance on the assessment and treatment of postmenopausal women at risk from fractures due to osteoporosis was recently published in Osteoporosis International as a joint effort of the International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (Ka...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-018-00512-x
更新日期:2019-03-01 00:00:00
abstract::The effects of long-term running were studied in 20 beagle dogs. Ten dogs ran from the age of 15 weeks to the age of 70 weeks in a progressive program for up to 40 km/day. Ten sister dogs spent the same time in individual cages. At the age of 70 weeks the spines of the dogs were studied with regard to mineral density ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555099
更新日期:1991-01-01 00:00:00
abstract::Discarded tissues, like human amniotic membranes and adipose tissue, were investigated for the application of Decellularized Human Amniotic Membrane (DAM) as a viable scaffold for transplantation of Adipose-derived stromal cells (ASCs) in bone regeneration of non-healing calvarial defects in rats. Amniotic membrane wa...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-020-00793-1
更新日期:2021-01-09 00:00:00
abstract::The low interference with growth expected in child for a cortisol analogue, deflazacort (DFZ), prompted us to verify if DFZ could affect growth less than prednisone (PDN). An interim analysis relative to 27 girls and 38 boys (out of 100 expected) aged 3-12 yrs, after a median period of 14 mo.s is reported. Children wi...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF02556381
更新日期:1991-04-01 00:00:00
abstract::In order to determine whether the bacterial bone resorbing agents lipopolysaccharide (LPS) and muramyl dipeptide (MDP) interact with osteoblasts, their effect on the synthesis of collagenase and tissue inhibitor or metalloproteinases (TIMP) from monolayer cultures of mouse osteoblast-like cells was investigated. All c...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556318
更新日期:1989-05-01 00:00:00
abstract::Osteoblasts in vitro differentiate from a proliferating to a mineralizing phenotype upon transfer to a medium rich in beta-glycerophosphate and ascorbic acid. The nutritional requirements of the cells at different stages of this differentiation process are not known. In other cell types, nutritional supplementation du...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-011-9537-6
更新日期:2011-12-01 00:00:00
abstract::We have previously shown that cyclosporin A (CsA) produces high bone remodeling with resorption exceeding formation and loss of bone volume in the rat. This may have important clinical implications where CsA is widely used in organ transplantation. 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) is a bone mineralizing hormone ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555980
更新日期:1990-09-01 00:00:00
abstract::Disturbances in mineral and bone metabolism are common in patients with chronic kidney disease (CKD), especially those undergoing dialysis. Renal osteodystrophy, which describes an alteration of bone morphology, is an important component of this systemic disorder and may explain the elevated risk of fracture which adv...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-020-00788-y
更新日期:2021-01-02 00:00:00
abstract::The values of in vivo T1 relaxation time (T1) of phosphorus atoms of wrist bone have been measured by phosphorus-31 magnetic resonance spectroscopy (MRS) in 65 menopausal women separated into three groups: (1) age-matched women without any paraclinical or clinical osteoporosis; (2) patients with paraclinical osteoporo...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00298583
更新日期:1995-06-01 00:00:00
abstract::Vit-D-Dependent calcium binding protein and parvalbumin have both been detected in ameloblasts and calcified cartilage by immunohistochemical techniques. These two Ca2+ binding proteins may play a crucial role in the local accumulation of Ca2+ ions during the process of mineralization. The mechanisms underlying the de...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02405306
更新日期:1984-01-01 00:00:00
abstract::The severest long-term complications of orthopedic joint-prostheses are associated with loosening of the implant-bone interface, due to adverse reactions in bone and subsequent weakening of the connection between the two materials. Mechanical stresses, caused by joint loading, play a key role in the adaption of interf...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02406143
更新日期:1984-01-01 00:00:00
abstract::Recent evidence of the occurrence of brushite in newly formed bone mineral prompted a study of the solubility properties of brushite:apatite mixtures under physiological conditions and the influence on them of pH, lactate, pyruvate, and, particularly, noncollagenous bone proteins (NCBPs). Brushite alone was surprising...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02411226
更新日期:1982-03-01 00:00:00
abstract::Osteoporosis is a bone disease leading to an increased fracture risk. It is considered a complex multifactorial genetic disorder with interaction of environmental and genetic factors. As a candidate gene for osteoporosis, we studied vitamin D binding protein (DBP, or group-specific component, Gc), which binds to and t...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-009-9251-9
更新日期:2009-08-01 00:00:00
abstract::The crystallinity of bone mineral at different stages of maturation has been measured by quantitative X-ray diffraction methods. Crystallinity measurements were made on tibial mid-diaphyses from 17-day embryonic chicks, newly-formed periosteal bone from embryonic chicks, and density-fractionated bone from post-hatch c...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02405032
更新日期:1983-01-01 00:00:00
abstract::Data on the association between dietary vitamin K intake and fracture risk are limited among Chinese. This study examined such an association in community-dwelling elderly in Hong Kong. We present data from 2,944 subjects (1,605 men, 1,339 women) who participated in a prospective cohort study. Baseline dietary intakes...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-012-9586-5
更新日期:2012-05-01 00:00:00
abstract::The accompanying article by Drs. Lian and Stein describes current thinking on how genes are organized in the nucleus and suggests that subnuclear localization is critical for the control of gene expression in bone. In particular, it is proposed that a major function of the osteoblast transcription factor, Runx2, is to...
journal_title:Calcified tissue international
pub_type: 评论,杂志文章,评审
doi:10.1007/s00223-002-1053-2
更新日期:2003-06-01 00:00:00
abstract::The existence of nutritional deficiency rickets among infants in sunny Riyadh was confirmed radiologically. Most of the rachitic infants were breast-fed, some received unsupplemented infant feeding formulae, and all live in an environment that is devoid of sunlight. Their mean age at the time of onset was 10.5 months....
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02405328
更新日期:1984-05-01 00:00:00
abstract::The aim of this study was to follow the changes in bone mineral density (BMD) and biochemical markers of bone turnover in 10 children (7.5-17.5 years of age) with severe juvenile idiopathic arthritis (JIA), during a 3-year therapy with salmon calcitonin (100 IU/day 2 months on and 2 off for a year and 200 IU/day for 2...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章
doi:10.1007/s00223-001-0008-3
更新日期:2001-07-01 00:00:00
abstract::Effects of a single dose of 200 IU of nasal salmon calcitonin (SCT) on calcium metabolism and biochemical markers of bone turnover were investigated in 12 healthy male volunteers in a randomized, placebo-controlled, cross-over design. The nasal spray was given in the morning, and subsequently blood and urine samples w...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF01320907
更新日期:1993-10-01 00:00:00
abstract::Osteoclastic bone resorption can be induced within the auditory bulla of the Mongolian gerbil by minute increases in air pressure. The objective of this study was to determine the rate at which osteoclasts are induced in areas of resorption and to compare the rate of osteoblast recruitment. Stainless steel tubes were ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556026
更新日期:1989-11-01 00:00:00
abstract::A comparative polarized light (PLM), scanning (SEM), and transmission (TEM) electron microscopy study was carried out on cross- and longitudinal sections of human lamellar bone in the tibiae of four male subjects aged 9, 23, 45, and 70 years. SEM analysis was also performed on rectangular-prismatic samples in order to...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF01673402
更新日期:1993-01-01 00:00:00
abstract::Urinary pyridinoline (pyr) and deoxypyridinoline (dpyr) are new markers for bone resorption, and serum osteocalcin reportedly indicates osteoblastic activity. Recently, a new ultrasound bone densitometer instrument has been developed that measures ultrasonic properties of the os calcis, namely, the speed of sound (SOS...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章
doi:10.1007/BF00298555
更新日期:1994-12-01 00:00:00
abstract::Biochemical markers applicable to the ovariectomized rat model can provide important tools for studying the bone remodeling process in this animal model of postmenopausal osteoporosis. We describe the development and application of two biochemical markers, a C-telopeptide (of type-I collagen) enzyme-linked immunosorbe...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002230010088
更新日期:2000-06-01 00:00:00
abstract::The pharmacokinetics and bioavailability of pamidronate were assessed in patients with breast cancer, 6 subjects received the drug intravenously and 7 orally. The initial plasma half-life of pamidronate was short (42 +/- 27 min) and the apparent total plasma clearance was high (471 +/- 298 ml/min). The renal clearance...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555856
更新日期:1991-12-01 00:00:00
abstract::Osteocalcin, the gamma-carboxyglutamic acid-containing protein, which is the most abundant noncollagenous protein of bone and dentin, is considered to play roles in bone formation and remodeling. It is unclear how the gamma-carboxyglutamic acid side-chains in osteocalcin coordinate to Ca2+, since the X-ray structure o...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002230010042
更新日期:2001-12-01 00:00:00
abstract::Fourier-transform (FT) Raman spectroscopy was used to characterize the organic and mineral components of biological and synthetic calcium phosphate minerals. Raman spectroscopy provides information on biological minerals that is complimentary to more widely used infrared methodologies as some infrared-inactive vibrati...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00305529
更新日期:1994-05-01 00:00:00
abstract::Noncarious cervical lesions have a multifactorial etiology. Mechanical stress has been identified as one of the factors, but little evidence exists for its cause-effect relationship. This study was conducted at three different pH levels to observe the surface loss on dentin beams under tension and compression. Bovine ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-005-0271-9
更新日期:2006-12-01 00:00:00