Abstract：
:To assess the efficacy of the intradermal route of administration of hepatitis A vaccine we conducted a study in hospital laboratory workers. Forty-three volunteers were given three different combinations of intradermal and intramuscular hepatitis A vaccine and compared with 18 controls given intramuscular vaccine only. The geometric mean titres (GMT) after one, two and three intradermal doses of 0.1 ml each were 4.5, 28 and 143 IU l-1 respectively. The GMT after one intramuscular dose in the controls was 163 IU l-1. The results indicate that the response to intradermal hepatitis A vaccine is poor and its use cannot be recommended.
journal_name
Vaccinejournal_title
Vaccineauthors
Brindle RJ,Morris CA,Berger R,Kurtz JBdoi
10.1016/0264-410x(94)90303-4subject
Has Abstractpub_date
1994-05-01 00:00:00pages
483-4issue
6eissn
0264-410Xissn
1873-2518pii
0264-410X(94)90303-4journal_volume
12pub_type
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