Abstract:
:A fundamental question in animal nutrition is the amino acid requirement induced by inflammation and immune response. The aim of the present experiment was to study the effect of chronic lung inflammation induced by injection of complete Freund adjuvant on amino acid metabolism in pigs. For 10 days, we compared plasma haptoglobine and amino acid concentrations of piglets with chronic lung inflammation (CFA) with those of pair-fed littermate healthy pigs (CONTROL). Tryptophan was the only amino acid for which the plasma concentration was continously decreasing and did not reach the control level at the end of the experimental period. We suggested that an increase in tryptophan catabolism under indoleamine 2, 3 dioxygenase activation and/or tryptophan incorporation into acute phase protein could explained the decrease in plasma tryptophan concentration in pigs suffuring from chronic lung inflammation.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Melchior D,Le Floc'h N,Sève Bdoi
10.1007/978-1-4615-0135-0_40subject
Has Abstractpub_date
2003-01-01 00:00:00pages
359-62eissn
0065-2598issn
2214-8019journal_volume
527pub_type
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