New concepts in organ transplantation.


:Major progress has been made in clinical transplantation over recent years due to close cooperation between clinical specialists and academic investigators. High success rates are evident by longer patient and graft survivals. Treatment procedures have been integrated into fixed protocols utilizing new chemical immunosuppressive reagents that have improved the management of transplanted patients. Further developments in organ transplantation through better surgical techniques have allowed grafts of pancreas, lungs, and intestine. Current transplant medicine has, however, its limitations, especially in the context of the donor organ shortage, the toxicity of immunosuppressive drugs, the chronic rejection activity, and the inability to produce a state of immunologic tolerance. This paper sought to review new concepts in organ transplantation, especially concerning immunologic tolerance and the organ donor shortage.


Transplant Proc


Paczek L,Pawlowska M,Krawczyk M,Rowinski W




Has Abstract


2004-06-01 00:00:00














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    abstract::The gold standard to assess renal function is the measurement of glomerular filtration rate (GFR). For practical reasons, renal function is often evaluated from serum creatinine (S Cr) or cystatin C (S Cys), and GFR is predicted from SCr. Ultrasound scanning of the kidneys is used only to evaluate renal morphology. Th...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Paleologo G,Abdelkawy H,Barsotti M,Basha A,Bernabini G,Bianchi A,Caprio F,Emad A,Grassi G,Nerucci B,Tregnaghi C,Rizzo G,Donadio C

    更新日期:2007-07-01 00:00:00

  • Frequency of Human Papilloma Virus Occurrence Among Pathological Changes of the Oral Cavity in Kidney Allotransplant Recipients Undergoing Long-Term Pharmacological Immunosuppressive Therapy.

    abstract::Recipients of allotransplants are more susceptible to viral infections, among which the human papilloma virus infection is an independent factor inducing precancerous lesions and cancers of both the anogenital and the cervicocephalic region. MATERIALS AND METHODS:The study included a group of 69 allogenic kidney tran...

    journal_title:Transplantation proceedings

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    authors: Szubińska-Lelonkiewicz D,Osiak M,Wychowański P,Siewert-Gutowska M,Fiedor P

    更新日期:2018-01-01 00:00:00

  • ATG-Fresenius inhibits blood circulating cell proliferation in a dose-dependent manner: an experimental study.

    abstract:INTRODUCTION:Antithymocyte globulin (ATG)-Fresenius (Neovii-Biotech, Graefelfing, Germany), a highly purified rabbit polyclonal antihuman T-lymphocyte immunoglobulin resulting from immunization of rabbits with the Jurkat T-lymphoblast cell line, is currently used for the prevention of acute rejection in patients receiv...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Werner I,Seitz-Merwald I,Kiessling AH,Kur F,Beiras-Fernandez A

    更新日期:2014-11-01 00:00:00

  • Intraoperative Continuous Veno-Venous Hemofiltration Facilitates Surgery in Liver Transplant Patients With Acute Renal Failure.

    abstract:INTRODUCTION:We have aggressively used continuous veno-venous hemofiltration (CVVH) on high model for end-stage liver disease (MELD) score liver transplant patients with acute kidney injury and hypothesized that the addition of intraoperative CVVH therapy would improve overall outcomes. METHODS:We performed a retrospe...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: LaMattina JC,Kelly PJ,Hanish SI,Ottmann SE,Powell JM,Hutson WR,Sivaraman V,Udekwu O,Barth RN

    更新日期:2015-07-01 00:00:00

  • Adoptive transfer of transplantation tolerance mediated by CD4+CD25+ and CD8+CD28- regulatory T cells induced by anti-donor-specific T-cell vaccination.

    abstract::Previous studies have shown that vaccinating rodents with anti-donor-specific T cells significantly prolonged allograft survival; however, the putative mechanism of the tolerance remains unclear. In this study, we used the model of heterotopic heart transplantation between the C57BL/6 donor mice and BALB/c recipient m...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Wang J,Zhang L,Tang J,Jiang S,Wang X

    更新日期:2008-06-01 00:00:00

  • Prevalence of polyomavirus among United Arab Emirates kidney transplant recipients: results from a single center.

    abstract:BACKGROUND:BK viremia and nephropathy are increasing problems in renal transplant recipients. The absence of a safe and effective antiviral therapy made screening-based prevention a recommended strategy. The prevalence of its reactivation among recipients of kidney transplants in the Middle East has not been well estab...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Boobes Y,Bernieh B,Hussain Q,Al Omary H,Al Hakim MR,Abayechi F,El Jack H,Khan I,Ahmed M

    更新日期:2015-05-01 00:00:00

  • Surveillance of Rejection After Intestinal Transplantation Using an Image Enhanced Endoscopy "VENCH" Scoring System.

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    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Chung CS,Tsai CC,Chen KC,Lin CK,Lee TH,Tsai HW,Chen Y

    更新日期:2021-01-01 00:00:00

  • Association of topical amphotericin B lipid complex treatment to standard therapy for rhinomaxillary mucormycosis after liver transplantation: a case report.

    abstract::Solid organ transplantation is becoming increasingly more common in the treatment of end-stage organ failure. The advent of newer immunosuppressive protocols and refined surgical techniques has allowed therapy to become standard care. Infection is a major and frequently life-threatening complication after transplantat...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Trasmonte MV,Jiménez JD,Santiago MÁ,Gálvez E,Jerez V,Pérez D,Robles M,Farje VK,Martínez P,Nieto P,Rubio JA

    更新日期:2012-09-01 00:00:00

  • Effect of posttraumatic donor's disseminated intravascular coagulation in intrathoracic organ donation and transplantation.

    abstract:INTRODUCTION:Our aim was to evaluate the influence on yield and function of intrathoracic organs from donors after severe cranial trauma complicated by disseminated intravascular coagulation (DIC). MATERIALS AND METHODS:This retrospective observational study in a patient cohort with severe cranial trauma reading to br...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Valdivia M,Chamorro C,Romera MA,Balandín B,Pérez M

    更新日期:2007-09-01 00:00:00

  • Impact of Secondary Insults in Brain Death After Traumatic Brain Injury.

    abstract::In addition to primary injury in severe head trauma, secondary systemic insults that aggravate the brain injury may result in fatal neurologic outcome. We aim to evaluate the correlation between brain death and secondary systemic insults in 100 patients with severe traumatic brain injury (TBI) admitted to the intensiv...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Heppekcan D,Ekin S,Çivi M,Aydın Tok D

    更新日期:2019-09-01 00:00:00

  • Modified liver-free multivisceral transplantation for a metastatic small bowel neuroendocrine tumor: a case report.

    abstract::Neuroendocrine tumors originating from the small bowel frequently metastasize to the lymph nodes and/or liver. Although surgical extirpation of the primary tumor and locoregional metastases epitomizes the management of patients with such tumors, this is not always possible with conventional surgical techniques. Nonres...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Frilling A,Giele H,Vrakas G,Reddy S,Macedo R,Al-Nahhas A,Wasan H,Clift AK,Gondolesi GE,Vianna RM,Friend P,Vaidya A

    更新日期:2015-04-01 00:00:00

  • Association Safety of Liver Preservation Solutions at the State University of Campinas From 2010 to 2014.

    abstract::The probable reason for mixing solutions during the harvesting procedure is due to the presence of multiple transplant teams that have their own solution usage tradition. Despite numerous studies comparing the efficacy of different preservation solutions, there is no study addressing the associating solution and if th...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Reigada CHP,de Ataide EC,Mattosinho TDAP,Costa LBE,Escanhoela CA,Boin IFSF

    更新日期:2017-05-01 00:00:00

  • Immunologic tolerance: tailored antigen.

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    journal_title:Transplantation proceedings

    pub_type: 杂志文章,评审


    authors: Krensky AM,Clayberger C

    更新日期:1996-08-01 00:00:00

  • Value of pretransplantation cytokine profiles for predicting acute rejection in renal transplant recipients.

    abstract::Episodes of acute rejection may represent an important risk factor for the development of chronic allograft nephropathy. Various studies have shown that pretransplant cytokine profiles in recipient blood are associated with transplant outcome. Serum samples were collected 24 hours before transplantation from 57 patien...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Lessan-Pezeshki M,Amirzargar A,Fathi A,Khatami MR,Einollahi B,Pourfarziani V,Azmandian J,Khosravi F,Ansaripour B,Nikbin B

    更新日期:2005-09-01 00:00:00

  • Real-time Intraoperative Fluorescent Lymphography: A New Technique for Lymphatic Sparing Surgery.

    abstract:BACKGROUND:Many surgical procedures can produce persistent lymphorrhea, lymphoceles, and lymphedema after lymph node and lymph vessel damage. Appropriate visualization of the lymphatic system is challenging. Indocyanine green (ICG) is a well-known nontoxic dye for lymphatic flow evaluation. ICG fluorescence-guided lymp...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Ietto G,Amico F,Soldini G,Chiappa C,Franchin M,Iovino D,Romanzi A,Saredi G,Cassinotti E,Boni L,Tozzi M,Carcano G

    更新日期:2016-11-01 00:00:00

  • Biliary reconstruction without T-tube in liver transplantation.

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    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Bacchella T,Figueira ER,Makdissi FF,Rocha-Santos V,Martino RB,Andraus W,Canedo LF,Machado MA,Machado MC

    更新日期:2004-05-01 00:00:00

  • Viral hepatitis B and C markers in the population of deceased donors in Poland.

    abstract::In the years 2001 to 2005 in Poland, 3146 potential deceased donors were referred with 2583 (82%) organs procured and 57 (2%) donors not used due to positive viral markers. According to Polish rules, in every case of possible organ harvest from a deceased donor we test viral markers of anti-HIV I/II, HBsAg, and anti-H...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Czerwiński J,Malanowski P,Wasiak D,Pszenny A,Gutowska D,Kwiatkowski A,Pacholczyk A,Chmura A,Małkowski P,Wałaszewski J

    更新日期:2007-11-01 00:00:00

  • In Vitro and In Vivo (Rabbit, Guinea Pig, Mouse) Properties of a Novel Resorbable Polymer and Allogenic Bone Composite for Guided Bone Regeneration and Orthopedic Implants.

    abstract:INTRODUCTION:Currently, there is no bone fixation material that could be fully replaced by the competent recipient bone. The creeping substitution of the bone graft by the recipient bone is the result of its unique potential related to the presence of bone morphogenetic proteins (BMPs). However, the size of the human b...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Gut G,Ambroziak M,Bojar W,Szaraniec B,Chłopek J,Flis S,Koronkiewicz M,Jastrzębski Z

    更新日期:2018-09-01 00:00:00

  • Low-dose dantrolene is effective in treating hyperthermia and hypercapnia, and seems not to affect recovery of the allograft after liver transplantation: case report.

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    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Shih TH,Chen KH,Pao YY,Yang SC,Chen CL,Huang CJ,Wang CH,Jawan B,Cheng KW,Yang CH

    更新日期:2010-04-01 00:00:00

  • Liver Transplantation for Budd-Chiari Syndrome With Large Solitary Focal Nodular Hyperplasia of the Liver in a Patient With Essential Thrombocythemia: Case Report. [Corrected].

    abstract::Budd-Chiari syndrome is a rare condition caused by interrupted hepatic venous outflow in the hepatic veins, inferior vena cava, or right atrium. Reports from the literature have delineated on focal nodular hyperplasia (FNH)-like lesions in association with Budd-Chiari Syndrome. To our knowledge, there are no reports a...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Alnajjar A,Al-Hussaini H,Al Sebayel M,Al-Kattan W,Elsiesy H

    更新日期:2015-09-01 00:00:00

  • Preservation injury patterns in liver transplantation associated with poor prognosis.

    abstract::Preservation injury (PI) is defined as hepatic dysfunction that occurs within 10 days of liver transplantation (OLT) but spontaneously resolves. However, we noted two new patterns: one characterized by histologic evidence of preservation injury that occurs at later than 10 days post-OLT (late PI), and a second, of per...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Lee YM,O'Brien CB,Yamashiki N,Behro M,Weppler D,Tzakis AG,Schiff ER

    更新日期:2003-12-01 00:00:00

  • Elevated tacrolimus levels associated with intravenous azithromycin and ceftriaxone: a case report.

    abstract::Drug interactions are a common occurrence with calcineurin inhibitors. We describe the case of a heart transplant recipient who developed increased tacrolimus blood levels after the administration of intravenous azithromycin and ceftriaxone. Tacrolimus levels decreased after the discontinuation of ceftriaxone and swit...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Shullo MA,Schonder K,Teuteberg JJ

    更新日期:2010-06-01 00:00:00

  • Effectiveness of the Gerundium Youth Educating Program in Hungary.

    abstract::The acceptance of brain death and the legitimation of organ transplantation is very much dependent on the general knowledge of the society. In Hungary, the legislation of brain death is based on presumed consent. There is no structural education about the topic so far. AIM:The role of the Gerundium program is to educ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Balogh E,Szabó B,Varga AK,Tóth B,Kovács D,Asztalos L,Nemes B

    更新日期:2019-05-01 00:00:00

  • Nonmarginal-donor duodenal ulcers caused by rejection after simultaneous pancreas and kidney transplantation: a case report.

    abstract:OBJECTIVE:Pancreas transplantation has been associated with the highest surgical complication rate among routinely performed organ transplant procedures. Complications can be caused not only from the pancreas itself but also from the simultaneously transplanted duodenum: gastrointestinal bleeding, duodenal ulcer, pseud...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Miyagi S,Sekiguchi S,Kawagishi N,Akamatsu Y,Satoh K,Takeda I,Fujimori K,Satomi S

    更新日期:2011-11-01 00:00:00

  • Implications of Clinical Mycophenolate Mofetil Dose According to Individual Body Weight in Japanese Renal Transplant Recipients.

    abstract:BACKGROUND:Mycophenolate mofetil (MMF) is generally administered at a fixed dose of 0.5-1.5 g/d without considering individual body weight (BW) in Japanese renal transplant outpatients receiving maintenance therapy. We aimed to investigate the implications of the area under the curve of mycophenolic acid (MPA AUC):MMF ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Yamada S,Shiohira H,Uehara H,Hokama N,Saitou S,Ooshiro Y

    更新日期:2016-01-01 00:00:00

  • Utility of Oxford Classification in Post-Transplant Immunoglobulin A Nephropathy.

    abstract:BACKGROUND:With increasing graft survival, post-transplant immunoglobulin A nephropathy (IgAN) has emerged as an important cause of chronic graft dysfunction in renal allograft recipients. We studied the clinico-pathological features of post-transplant IgAN regardless of the primary disease. The aim was to study the us...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Agrawal V,Singh A,Kaul A,Verma R,Jain M,Pandey R

    更新日期:2017-12-01 00:00:00

  • Insights into subclinical rejection.

    abstract::Several groups have performed graft biopsies at set times posttransplant ("protocol biopsies") and found unequivocal histologic criteria for acute rejection in a high proportion of patients with stable graft function. The significance of "subclinical" rejection remains controversial. Our group and others have shown th...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,评审


    authors: Rush D,Winnipeg Transplant Group.

    更新日期:2004-03-01 00:00:00

  • Assessing the risk of infection and rejection in Hispanic renal transplant recipients by means of an adenosine triphosphate release assay.

    abstract:INTRODUCTION:Because of the necessary immunosuppression, transplant recipients have a high risk of infection. Conversely, underimmunosuppression carries with it the risk of rejection. It would be quite useful to have a test that could differentiate between infection and rejection in renal transplant patients and better...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Cadillo-Chávez R,de Echegaray S,Santiago-Delpín EA,Rodríguez-Trinidad AT,Camacho-Carrazo B,Alfaro T,Saavedra-Pozo M,Carrasquillo L,González-Caraballo ZA,Morales-Otero LA

    更新日期:2006-04-01 00:00:00

  • Donate a Piece of Liver: Is This an Option Accepted by Future Nurses of Pomeranian Medical University in Poland?

    abstract:BACKGROUND:Liver transplantation from living donors (LLD) has become a viable and important source of liver grafts. The objective of this study was to analyze the attitude of nursing students at the Pomeranian Medical University in Poland on donation of live liver, and to determine the factors that affect it. METHODS:...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Mikla M,Rios A,Lopez-Navas A,Gorzkowicz B,Kilanska D,Martinez-Alarcón L,Ramis G,Ramirez P,Lopez Montesinos MJ

    更新日期:2016-09-01 00:00:00

  • Intestinal water and electrolyte absorption and secretion.

    abstract::Diarrhea is a frequent complication of small bowel transplantation in patients and experimental models. Although there are many potential causes, the underlying basis for most are not fully understood. Improved therapeutic approaches will come about through better understanding of mechanisms of bowel adaptation and re...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,评审


    authors: Chang EB

    更新日期:1996-10-01 00:00:00