Abstract:
:In patients with end-stage chronic kidney disease (CKD) and type 1 diabetes mellitus (DM 1), simultaneous pancreas-kidney (SPK) transplantation is currently considered the gold standard therapy. The aim of this study was to analyze and report the long-term clinical outcomes of the 23 SPK transplantations performed at our institution over an 84-month period (January 1, 2000 to December 31, 2006). A prospective analysis of these patients included donor, recipient, and transplantation characteristics. The only requirements for transplantation were blood group compatibility and a negative cross-match. Bladder drainage via pancreaticoduodenocystostomy was performed in all of the patients. Due to a pulmonary embolus 1 patient (4.3%) died at 2 months. The actuarial patient survival rates at 3 months and 1, 3, and 5 years were 95.6%. Causes for the renal graft loss were chronic allograft nephropathy in 3 cases (13%) and death of the patient in 1 case (4.3%). The actuarial censored renal allograft survival rates at 3 months and at 1 year were 100%, and at 3 and 5 years were 91.3%. Causes for the renal graft loss were chronic rejection in 1 case (4.3%) and patient death in 1 case (4.3%). The actuarial censored pancreatic allograft survival rates at 3 months and at 1 and 3 years were 100%, and at 5 years was 95.6%. The results of this work add further evidence that SPK is the gold standard therapy for selected patients with end-stage CKD due to DM 1.
journal_name
Transplant Procjournal_title
Transplantation proceedingsauthors
Rossi M,Lai Q,Spoletini G,Poli L,Nudo F,Ferretti S,Della Pietra F,Pugliese F,Ferretti G,Novelli G,Pretagostini R,Berloco PBdoi
10.1016/j.transproceed.2008.05.059subject
Has Abstractpub_date
2008-07-01 00:00:00pages
2024-6issue
6eissn
0041-1345issn
1873-2623pii
S0041-1345(08)00642-8journal_volume
40pub_type
杂志文章abstract::Using colchicine to treat an acute gout crisis in an organ transplant recipient (TR) on cyclosporine (CsA) may result in life-threatening intoxication. We report the case of a 59-year-old kidney transplant recipient on CsA who was treated with colchicine for acute gout crisis. Seven days later, he developed rhabdomyol...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2012.09.028
更新日期:2012-11-01 00:00:00
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更新日期:2014-09-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2012.11.023
更新日期:2013-06-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2009.02.093
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Hypertrophic cardiomyopathy (HCM) is a genetic heart muscle disease characterized by asymmetric or symmetric ventricular hypertrophy in the absence of an obvious clinical cause. Orthotopic heart transplantation (OHT) has been performed in patients who have refractory symptoms despite medical therapy and surg...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2013.12.052
更新日期:2014-06-01 00:00:00
abstract:INTRODUCTION:Laparoscopic surgery is rapidly emerging as the standard of care for a variety of urological conditions, even among patients who have undergone prior renal transplantation. We describe the technique of bilateral native nephrectomy and allograft nephrectomy by laparoscopy. CASE REPORT:A 32-year-old man wit...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2005.03.108
更新日期:2005-06-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2010.09.070
更新日期:2010-12-01 00:00:00
abstract:INTRODUCTION:Genetic predisposition, including polymorphisms of the renin-angiotensin system (RAS) genes, are among the potential factors that may affect the occurrence of hypertension, anemia, or erythrocytosis as well as transplanted kidney function. However, the association of the RAS genes polymorphism and the kidn...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2011.07.016
更新日期:2011-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2013.11.092
更新日期:2014-04-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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更新日期:2013-07-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章,评审
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更新日期:1998-08-01 00:00:00
abstract::Current studies have shown that living-donor liver transplantation (LDLT) for hepatocelluar carcinoma (HCC) satisfying the Milan criteria does not compromise patient survival or increase HCC recurrence compared with deceased-donor liver transplantation (DDLT). For patients with HCC beyond the Milan criteria, however, ...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2013.08.052
更新日期:2013-10-01 00:00:00
abstract:UNLABELLED:Certain characteristics of the donor have implications for the early and late survival of transplants. The trends show a progressive worsening in the clinical profile of heart donors. Our objective was to analyze changes in the clinical characteristics of donors. MATERIALS AND METHODS:This retrospective stu...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2006.08.021
更新日期:2006-10-01 00:00:00
abstract::Enteric-coated mycophenolate sodium (EC-MPS) is designed to reduce mycophenolate acid (MPA)-related upper gastrointestinal (GI) adverse events (AEs). A multicenter, open-label, Latin American study in stable renal transplant patients is ongoing to assess the safety of the conversion from mycophenolate mofetil (MMF) to...
journal_title:Transplantation proceedings
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.transproceed.2004.07.031
更新日期:2004-07-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2012.07.056
更新日期:2012-10-01 00:00:00
abstract::Pretreatment of splenic macrophages with anti-Ia serum specific for the various known I subregions and complement deleted the macrophages required for an in vitro antibody response to burro erythrocytes. Antibodies directed at the gene products of the I-J subregion, however, were unique in that they did not require th...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:
更新日期:1979-03-01 00:00:00
abstract:BACKGROUND:Renal transplantation has been established as a treatment for end-stage renal disease (ESRD) due to diabetic nephropathy. However, few studies have focused on the outcome after renal transplantation in patients with ESRD and type 2 diabetic nephropathy. To investigate the effect of renal transplantation on E...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2014.12.047
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:We previously reported both in vivo and in vitro effects of rapamycin on urothelial carcinoma. Clinically, the use of rapamycin could not completely prevent the recurrence of urothelial carcinoma. Therefore, we designed this study to compare the difference of efficacy between early and late use of rapamycin ...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2013.11.132
更新日期:2014-05-01 00:00:00
abstract:INTRODUCTION:Transplant rates are low among highly sensitized patients with preformed anti-HLA antibodies, because of the additional immunologic barrier, the increased risk of rejection, and the greater chance of early graft loss. Intravenous infusion of pooled human immune globulin (IVIG) is immunomodulatory, neutrali...
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2009.08.006
更新日期:2009-10-01 00:00:00
abstract:UNLABELLED:The purpose of this study was to analyze risk factors for acute rejection (AR) and long-term outcomes in simultaneous kidney-pancreas transplant (SKPT) patients enrolled in a prospective, multicenter study of daclizumab (DAC) versus no antibody induction. METHODS:A total of 298 SKPT patients were randomized...
journal_title:Transplantation proceedings
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2005-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:2009-10-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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更新日期:2016-07-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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更新日期:2009-11-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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更新日期:2020-06-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2014.11.028
更新日期:2015-01-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2009.06.200
更新日期:2009-11-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2009.03.097
更新日期:2009-05-01 00:00:00
abstract::Ovarian dysfunction, anovulatory vaginal bleeding, amenorrhea, high prolactin levels, and loss of libido are the causes of infertility in women with chronic renal failure. After renal transplantation, endocrine function generally improves after recovery of renal function. In this study we retrospectively evaluated the...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2003.11.011
更新日期:2004-01-01 00:00:00
abstract::Pericardial effusion and cardiac tamponade following renal transplantation have been recognized as a potentially serious complications associated with the use of sirolimus for immunosuppression. Our study aims to analyze the development of sirolimus-associated pericardial effusion. Patients who underwent renal transpl...
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2019.04.043
更新日期:2019-01-01 00:00:00
abstract::Liver transplantation is known as a highly complex procedure. Several variables can affect the outcome. The present study is a retrospective multivariate analysis of the outcomes of primary liver transplant recipients from deceased donors. From November 2006 through January 2009, 155 patients received first liver tran...
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2010.01.014
更新日期:2010-03-01 00:00:00