Biosynthesis of isoprenoid compounds in cattle filarial parasite Setaria digitata.

Abstract:

:The biological significance of isoprenoid compounds such as ubiquinones, prenols and sterols have been well established. The presence and biological function of the two quinones Q6 and Q8 in the cattle filarial parasite Setaria digitata have already been reported. Inhibition of the function of quinone was already shown to be an effective means of controlling the filarial parasite. Detailed investigations of the non-saponifiable lipids from S. digitata using column, thin layer, reverse phase and high performance liquid chromatography showed the presence and formation of isoprenoid compounds such as prenols and sterols, in addition to the two quinones. Blocking of the biosynthesis of these useful compounds may prove to be an additional means of control of filarial parasites.

authors

Kumari GA,Santhamma KR,Raj RK

doi

10.1006/bbrc.1994.2624

subject

Has Abstract

pub_date

1994-11-30 00:00:00

pages

24-9

issue

1

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(84)72624-6

journal_volume

205

pub_type

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