Abstract:
:The biological significance of isoprenoid compounds such as ubiquinones, prenols and sterols have been well established. The presence and biological function of the two quinones Q6 and Q8 in the cattle filarial parasite Setaria digitata have already been reported. Inhibition of the function of quinone was already shown to be an effective means of controlling the filarial parasite. Detailed investigations of the non-saponifiable lipids from S. digitata using column, thin layer, reverse phase and high performance liquid chromatography showed the presence and formation of isoprenoid compounds such as prenols and sterols, in addition to the two quinones. Blocking of the biosynthesis of these useful compounds may prove to be an additional means of control of filarial parasites.
journal_name
Biochem Biophys Res Communjournal_title
Biochemical and biophysical research communicationsauthors
Kumari GA,Santhamma KR,Raj RKdoi
10.1006/bbrc.1994.2624subject
Has Abstractpub_date
1994-11-30 00:00:00pages
24-9issue
1eissn
0006-291Xissn
1090-2104pii
S0006-291X(84)72624-6journal_volume
205pub_type
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