Ulnar neuropathy. Incidence, outcome, and risk factors in sedated or anesthetized patients.

Abstract:

BACKGROUND:Ulnar neuropathy is well-recognized as a potential complication of procedures performed on anesthetized patients. However, reported outcomes and risk factors for this problem are based on small series and anecdotes. METHODS:We retrospectively reviewed the perioperative courses of 1,129,692 consecutive patients who underwent diagnostic and noncardiac surgical procedures with concurrent anesthetic management at the Mayo Clinic from 1957 through 1991 (inclusive). The medical diagnoses of patients who had these procedures were scanned for 26 diagnoses associated with neuropathy. Persistent neuropathy of an ulnar nerve was defined as a sensory or motor deficit of greater than 3 months' duration. Risk factors anecdotally associated with persistent neuropathy were analyzed by comparing patients with an ulnar neuropathy with control subjects in a 1:3 case-control study. RESULTS:Persistent ulnar neuropathies were identified in 414 patients, a rate of 1 per 2,729 patients. Of these, 38 (9%) patients had bilateral neuropathies. Approximately equal numbers of the neuropathies included sensory loss only or mixed sensory and motor loss. Initial symptoms form most neuropathies were noted more than 24 h after the procedure. Factors associated with persistent ulnar neuropathy included male gender and a duration of hospitalization of more than 14 days (P < 0.01). Neuropathy was more likely to develop in very thin and obese patients than in patients with average body habitus. Neither the type of anesthetic technique nor the patient position was found to be associated with this neuropathy. Of the 382 patients who survived the 1st postoperative yr, 53% regained complete motor function and sensation and were asymptomatic. Of those with neuropathies persisting for more than 1 yr, most had moderate or greater disability from pain or weakness. CONCLUSIONS:These data suggest that perioperative ulnar neuropathies are associated with factors other than general anesthesia and intraoperative positioning. Men at the extremes of body habitus who have prolonged hospitalizations are particularly susceptible to development of ulnar neuropathies.

journal_name

Anesthesiology

journal_title

Anesthesiology

authors

Warner MA,Warner ME,Martin JT

subject

Has Abstract

pub_date

1994-12-01 00:00:00

pages

1332-40

issue

6

eissn

0003-3022

issn

1528-1175

journal_volume

81

pub_type

杂志文章
  • Retrograde light-guided laryngoscopy for tracheal intubation: clinical practice and comparison with conventional direct laryngoscopy.

    abstract:BACKGROUND:Tracheal intubation with conventional laryngoscopy requires many trials until beginners are sufficiently skilled in intubating patients safely. To facilitate intubation, the authors used retrograde light-guided laryngoscopy (RLGL) and compared its feasibility with conventional direct laryngoscopy (DL). METH...

    journal_title:Anesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/ALN.0b013e31828877c0

    authors: Yang T,Hou J,Li J,Zhang X,Zhu X,Ni W,Mao Y,Deng X

    更新日期:2013-05-01 00:00:00

  • Buprenorphine disrupts sleep and decreases adenosine concentrations in sleep-regulating brain regions of Sprague Dawley rat.

    abstract:BACKGROUND:Buprenorphine, a partial μ-opioid receptor agonist and κ-opioid receptor antagonist, is an effective analgesic. The effects of buprenorphine on sleep have not been well characterized. This study tested the hypothesis that an antinociceptive dose of buprenorphine decreases sleep and decreases adenosine concen...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0b013e31822e9f85

    authors: Gauthier EA,Guzick SE,Brummett CM,Baghdoyan HA,Lydic R

    更新日期:2011-10-01 00:00:00

  • Addition of sodium bicarbonate to lidocaine decreases the duration of peripheral nerve block in the rat.

    abstract:BACKGROUND:Adding sodium bicarbonate to lidocaine to enhance its efficacy during peripheral nerve block is controversial. The authors studied the effect of adding sodium bicarbonate to lidocaine with and without epinephrine versus equivalent alkalinization by sodium hydroxide (NaOH) on onset, degree, and duration of pe...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200010000-00028

    authors: Sinnott CJ,Garfield JM,Thalhammer JG,Strichartz GR

    更新日期:2000-10-01 00:00:00

  • Positive end-expiratory pressure improves respiratory function in obese but not in normal subjects during anesthesia and paralysis.

    abstract:BACKGROUND:Morbidly obese patients, during anesthesia and paralysis, experience more severe impairment of respiratory mechanics and gas exchange than normal subjects. The authors hypothesized that positive end-expiratory pressure (PEEP) induces different responses in normal subjects (n = 9; body mass index < 25 kg/m2) ...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000542-199911000-00011

    authors: Pelosi P,Ravagnan I,Giurati G,Panigada M,Bottino N,Tredici S,Eccher G,Gattinoni L

    更新日期:1999-11-01 00:00:00

  • Optimization of the radioimmunoassays for measuring fentanyl and alfentanil in human serum.

    abstract::Measurement of serum fentanyl and alfentanil concentrations by radioimmunoassay (RIA) may result in significant errors and high variability when the technique described in the available fentanyl and alfentanil RIA kits is used. The authors found a 29-94% overestimation of measured fentanyl and alfentanil serum levels ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198409000-00010

    authors: Schüttler J,White PF

    更新日期:1984-09-01 00:00:00

  • Halothane and isoflurane decrease alveolar epithelial fluid clearance in rats.

    abstract:BACKGROUND:Active sodium transport is the primary mechanism that drives alveolar fluid clearance. In the current study, the effects of exposure to halothane and isoflurane on alveolar fluid clearance in rats were evaluated. METHODS:Rats were exposed to either halothane (0.4% for 6 h or 2% for 2 h) or isoflurane (0.6% ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199803000-00027

    authors: Rezaiguia-Delclaux S,Jayr C,Luo DF,Saïdi NE,Meignan M,Duvaldestin P

    更新日期:1998-03-01 00:00:00

  • Comparison of enflurane, halothane, and isoflurane for diagnostic and therapeutic procedures in children with malignancies.

    abstract::The authors performed a randomized, prospective trial comparing enflurane, halothane, and isoflurane (each administered with nitrous oxide) to establish which inhaled anesthetic produced the fewest complications and the most rapid induction of anesthesia for children undergoing general anesthesia for diagnostic proced...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-198512000-00015

    authors: Fisher DM,Robinson S,Brett CM,Perin G,Gregory GA

    更新日期:1985-12-01 00:00:00

  • Comparison of MAC and the rate of rise of alveolar concentration of sevoflurane with halothane and isoflurane in the dog.

    abstract::The anesthetic requirements for sevoflurane, isoflurane, and halothane were determined in mongrel dogs. The MACs (minimum alveolar concentration) of sevoflurane, isoflurane, and halothane were 2.36 +/- 0.46% (n = 18), 1.39 +/- 0.25% (n = 10), and 0.89 +/- 0.20% (n = 12), respectively (mean +/- SD). In agreement with s...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198803000-00020

    authors: Kazama T,Ikeda K

    更新日期:1988-03-01 00:00:00

  • Preemptive intravenous morphine-6-glucuronide is ineffective for postoperative pain relief.

    abstract:BACKGROUND:Morphine-6-glucuronide (M-6-G), a major metabolite of morphine, is reported to be more potent than morphine when administered intrathecally; however, its efficiency remains under debate when administered intravenously. This study was designed to assess the analgesic efficiency of intravenous M-6-G for the tr...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-200002000-00015

    authors: Motamed C,Mazoit X,Ghanouchi K,Guirimand F,Abhay K,Lieutaud T,Bensaid S,Fernandez C,Duvaldestin P

    更新日期:2000-02-01 00:00:00

  • Mortality experience among anesthesiologists, 1954-1976.

    abstract::To determine whether anesthesiologists, because of prolonged exposure to halothane or other inhalational anesthetics, might have higher death rates from all causes, from cancer, and from hepatic or renal disease than other physicians, the mortality rates of male and female members of the American Society of Anesthesio...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-197909000-00003

    authors: Lew EA

    更新日期:1979-09-01 00:00:00

  • High-efficiency delivery of salbutamol with a metered-dose inhaler in narrow tracheal tubes and catheters.

    abstract::We sought to determine the percent delivery by metered-dose inhaler (MDI) of a preparation of salbutamol (albuterol) to the distal end of either pediatric-size tracheal tubes or a narrow-gauge catheter. A bench model consisting of a swivel actuator; 3.0-6.0-mm ID tracheal tubes all 16 cm in length or a 19-G (standard ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199102000-00024

    authors: Taylor RH,Lerman J

    更新日期:1991-02-01 00:00:00

  • Systemic lidocaine blocks nerve injury-induced hyperalgesia and nociceptor-driven spinal sensitization in the rat.

    abstract:BACKGROUND:Repetitive C-fiber stimulation induces a state of facilitated processing of sensory information in the dorsal horn, while chronic nerve compression gives rise to a hyperalgesic state, characterized by spontaneous neuronal activity generated by voltage-sensitive sodium channels, as well as spinal facilitation...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:

    authors: Abram SE,Yaksh TL

    更新日期:1994-02-01 00:00:00

  • Role of spinal cyclooxygenase in human postoperative and chronic pain.

    abstract:BACKGROUND:Nonsteroidal antiinflammatory drugs are commonly used to treat postoperative and chronic pain. Animal studies suggest that these drugs act, in part, by blocking prostaglandin production in the spinal cord. The authors tested intrathecal ketorolac in patients with chronic or postoperative pain. METHODS:After...

    journal_title:Anesthesiology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/ALN.0b013e3181d94dc0

    authors: Eisenach JC,Curry R,Rauck R,Pan P,Yaksh TL

    更新日期:2010-05-01 00:00:00

  • Effects of nonsteroidal antiinflammatory drugs on patient-controlled analgesia morphine side effects: meta-analysis of randomized controlled trials.

    abstract::Nonsteroidal antiinflammatory drugs (NSAIDs) are commonly combined with intravenous morphine patient-controlled analgesia to relieve postoperative pain. NSAIDs have a documented 30-50% sparing effect on morphine consumption. However, most of the studies have not demonstrated a decrease in morphine adverse effects. A m...

    journal_title:Anesthesiology

    pub_type: 杂志文章,meta分析

    doi:10.1097/00000542-200506000-00027

    authors: Marret E,Kurdi O,Zufferey P,Bonnet F

    更新日期:2005-06-01 00:00:00

  • Event-related functional magnetic resonance imaging of a low dose of dexmedetomidine that impairs long-term memory.

    abstract:BACKGROUND:Work suggests the amnesia from dexmedetomidine (an α2-adrenergic agonist) is caused by a failure of information to be encoded into long-term memory and that dexmedetomidine might differentially affect memory for emotionally arousing material. We investigated these issues in humans using event-related neuroim...

    journal_title:Anesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/ALN.0b013e31826be467

    authors: Hayama HR,Drumheller KM,Mastromonaco M,Reist C,Cahill LF,Alkire MT

    更新日期:2012-11-01 00:00:00

  • Differential behavioral effects of peripheral and systemic morphine and naloxone in a rat model of repeated acute inflammation.

    abstract:BACKGROUND:It has been reported that opioid antinociceptive effects are enhanced in animal models of inflammation, but it remains unclear whether this sensitization to morphine is related to predominant central or peripheral increased effects. METHODS:The authors compared the behavioral effects of intraplantar and int...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200105000-00027

    authors: Perrot S,Guilbaud G,Kayser V

    更新日期:2001-05-01 00:00:00

  • Ventilatory effects of clonidine alone and in the presence of alfentanil, in human volunteers.

    abstract::Clonidine, an alpha 2-adrenergic agonist, can potentiate opioid-induced analgesia. In a double-blind placebo-controlled study in human volunteers, we sought to determine whether clonidine also potentiates opioid-induced respiratory depression. Hypercapnic ventilatory responses (minute ventilation, mean inspiratory flo...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000542-199206000-00005

    authors: Jarvis DA,Duncan SR,Segal IS,Maze M

    更新日期:1992-06-01 00:00:00

  • Treatment of iron deficiency anemia in orthopedic surgery with intravenous iron: efficacy and limits: a prospective study.

    abstract:BACKGROUND:Preoperative anemia is frequent in patients undergoing orthopedic surgery. The purpose of this study was to assess the preoperative increase of hemoglobin in iron deficiency anemia patients treated with intravenous iron. METHODS:After obtaining written informed consent, 20 patients with iron deficiency anem...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/01.anes.0000291441.10704.82

    authors: Theusinger OM,Leyvraz PF,Schanz U,Seifert B,Spahn DR

    更新日期:2007-12-01 00:00:00

  • Exercise produces sensitivity to metocurine.

    abstract::Chronic muscle disuse decreases the sensitivity of skeletal muscle to nondepolarizing relaxants, such as metocurine (MTC). In this study, the authors determined whether chronic conditioning would produce the opposite effect and increase the sensitivity of skeletal muscle to MTC. Five dogs were exercised by daily runni...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198906000-00015

    authors: Gronert GA,White DA,Shafer SL,Matteo RS

    更新日期:1989-06-01 00:00:00

  • Individual differences in acute pain-induced endogenous analgesia predict time to resolution of postoperative pain in the rat.

    abstract:BACKGROUND:Chronic postsurgical pain, a significant public health problem, occurs in 10 to 50% of patients undergoing major surgery. Acute pain induces endogenous analgesia termed conditioned pain modulation (CPM), and the strength of CPM preoperatively predicts the likelihood of chronic postsurgical pain. The relation...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0000000000000593

    authors: Peters CM,Hayashida K,Suto T,Houle TT,Aschenbrenner CA,Martin TJ,Eisenach JC

    更新日期:2015-04-01 00:00:00

  • Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats.

    abstract:BACKGROUND:The pharmacology of oxycodone is poorly understood despite its growing clinical use. The discrepancy between its good clinical effectiveness after systemic administration and the loss of potency after spinal administration led the authors to study the pharmacodynamic effects of oxycodone and its metabolites ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200610000-00027

    authors: Lemberg KK,Kontinen VK,Siiskonen AO,Viljakka KM,Yli-Kauhaluoma JT,Korpi ER,Kalso EA

    更新日期:2006-10-01 00:00:00

  • Alveolar-to-arterial-to-venous anesthetic partial pressure differences in humans.

    abstract::To determine the correlation between the partial pressures of anesthetics in venous and arterial blood (Pv and Pa), and to assess whether this correlation was better than that between the partial pressure of anesthetic in alveolar gas (PA) and Pa, isoflurane (n = 4) or halothane (n = 4) was administered to eight patie...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198904000-00014

    authors: Carpenter RL,Eger EI 2nd

    更新日期:1989-04-01 00:00:00

  • Effects of propofol and thiopental in isolated rat aorta and pulmonary artery.

    abstract::This study was performed to determine if direct arterial dilating actions of propofol contribute to the drug's hypotensive actions. The effects of propofol were compared with those of thiopental on isolated vascular ring preparations from rat thoracic aorta and pulmonary artery. Thoracic aortic ring responses were eva...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199211000-00019

    authors: Park WK,Lynch C 3rd,Johns RA

    更新日期:1992-11-01 00:00:00

  • Interaction of neuromuscular blocking effects of neomycin and polymyxin B.

    abstract::Neomycin and polymyxin B produce neuromuscular blocks with distinct features by different mechanisms of action. In eight anesthetized cats the authors studied their interaction by examining the neuromuscular block produced by an equipotent mixture. Values of onset, potency, dose-response relations, duration and revers...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-197903000-00010

    authors: Lee C,de Silva AJ

    更新日期:1979-03-01 00:00:00

  • Cerebral extracellular glucose and lactate concentrations during and after moderate hypoxia in glucose- and saline-infused rats.

    abstract::To assess the effect of a glucose infusion on brain extracellular fluid (ECF) during systemic hypoxia, changes in glucose and lactate concentrations in cerebral ECF during and after moderate hypoxic hypoxia were measured in adult, conscious, unrestrained rats, with a microdialysis probe in the posterior hippocampus. T...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199210000-00017

    authors: Harada M,Okuda C,Sawa T,Murakami T

    更新日期:1992-10-01 00:00:00

  • Anesthetic interactions of midazolam and fentanyl: is there acute tolerance to the opioid?

    abstract::The anesthetic effects and interactions of midazolam and fentanyl were determined in terms of their reduction of enflurane MAC in dogs, and the effects of their specific antagonists were also investigated. Control enflurane MAC was determined by the tail clamp method in 18 mongrel dogs. Each animal then received an iv...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198904000-00021

    authors: Schwieger IM,Hall RI,Szlam F,Hug CC Jr

    更新日期:1989-04-01 00:00:00

  • The pharmacokinetics and hemodynamic effects of intravenous and intramuscular dexmedetomidine hydrochloride in adult human volunteers.

    abstract:BACKGROUND:Dexmedetomidine is an alpha 2 agonist with potential utility in clinical anesthesia for both its sedative and sympatholytic properties. METHODS:The pharmacokinetics and hemodynamic changes that occurred in ten healthy male volunteers were determined after administration of dexmedetomidine 2 micrograms/kg by...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199305000-00002

    authors: Dyck JB,Maze M,Haack C,Vuorilehto L,Shafer SL

    更新日期:1993-05-01 00:00:00

  • A randomized study of the effects of single-dose gabapentin versus placebo on postoperative pain and morphine consumption after mastectomy.

    abstract:BACKGROUND:The anticonvulsant gabapentin has proven effective for neuropathic pain in three large placebo-controlled clinical trials. Experimental and clinical studies have demonstrated antihyperalgesic effects in models involving central neuronal sensitization. It has been suggested that central neuronal sensitization...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-200209000-00007

    authors: Dirks J,Fredensborg BB,Christensen D,Fomsgaard JS,Flyger H,Dahl JB

    更新日期:2002-09-01 00:00:00

  • Serious complications related to regional anesthesia: results of a prospective survey in France.

    abstract:BACKGROUND:Serious complications related to regional anesthesia have previously been described primarily in case reports and retrospective surveys. The authors prospectively evaluated a multicenter series of regional anesthetics, using preplanned criteria to measure the incidence and characteristics of associated serio...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199709000-00005

    authors: Auroy Y,Narchi P,Messiah A,Litt L,Rouvier B,Samii K

    更新日期:1997-09-01 00:00:00

  • Early but no long-term benefit of regional compared with general anesthesia for ambulatory hand surgery.

    abstract:BACKGROUND:The purpose of this study was to determine whether either regional anesthesia (RA) or general anesthesia (GA) provided the best analgesia with the fewest adverse effects up to 2 weeks after ambulatory hand surgery. METHODS:Patients undergoing ambulatory hand surgery were randomly assigned to RA (axillary br...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-200408000-00028

    authors: McCartney CJ,Brull R,Chan VW,Katz J,Abbas S,Graham B,Nova H,Rawson R,Anastakis DJ,von Schroeder H

    更新日期:2004-08-01 00:00:00