Effects of propofol and thiopental in isolated rat aorta and pulmonary artery.

abstract：BACKGROUND:Activation of the complement system is one component of the inflammatory response. Various components of the complement system participate in killing foreign organisms, recruiting immune cells, enhancing edema, and stimulating cytokine formation. Complement-mediated enhancement of the inflammation surroundin...

journal_title：Anesthesiology

authors： Clark JD,Qiao Y,Li X,Shi X,Angst MS,Yeomans DC

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:In airway smooth muscle (ASM), volatile anesthetics deplete sarcoplasmic reticulum (SR) Ca(2+) stores by increasing Ca(2+) "leak." Accordingly, SR replenishment becomes dependent on Ca(2+) influx. Depletion of SR Ca(2+) stores triggers Ca(2+) influx via specific plasma membrane channels, store-operated Ca(2+...

journal_title：Anesthesiology

authors： Pabelick CM,Ay B,Prakash YS,Sieck GC

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Dynorphin A in the spinal cord is considered to contribute to nociceptive stimuli. However, it has not yet been determined whether activation of the spinal dynorphinergic system under nociceptive stimuli plays a role in direct acceleration of the ascending nociceptive pathway. In this study, the authors inve...

journal_title：Anesthesiology

authors： Taketa Y,Niikura K,Kobayashi Y,Furuya M,Shimizu T,Narita M,Imai S,Kuzumaki N,Maitani Y,Yamazaki M,Inada E,Iseki M,Suzuki T,Narita M

更新日期：2010-02-01 00:00:00

abstract：:Statin therapy is well established for prevention of cardiovascular disease. Statins may also reduce postoperative mortality and morbidity via a pleiotropic (non-lipid-lowering) effect. The authors conducted a meta-analysis to determine the influence of statin treatment on adverse postoperative outcomes in patients un...

journal_title：Anesthesiology

authors： Hindler K,Shaw AD,Samuels J,Fulton S,Collard CD,Riedel B

更新日期：2006-12-01 00:00:00

abstract：:In MH, skeletal muscle acutely and unexpectedly increases its oxygen consumption and lactate production, resulting in greater heat production, respiratory and metabolic acidosis, muscle ridigity, sympathetic stimulation, and increased cellular permeability. The best-accepted theory is that MH is due to an inability to...

journal_title：Anesthesiology

authors： Gronert GA

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:Memory function under anesthesia is undesired but may arise from light hypnosis as well as stress-enhanced learning during surgery. The bispectral index (BIS, Aspect Medical Systems, Norwood, MA) is a monitor of hypnotic state that can help to avoid light hypnosis (i.e., BIS above 60). This study tested the ...

journal_title：Anesthesiology

authors： Kerssens C,Gaither JR,Sebel PS

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Perfluorocarbon liquids are being used experimentally and in clinical trials for the treatment of acute lung injury. Their resemblance to inhaled anesthetic agents suggests the possibility of application by vaporization. The authors' aim was to develop the technical means for perfluorocarbon vaporization and...

journal_title：Anesthesiology

authors： Bleyl JU,Ragaller M,Tschö U,Regner M,Kanzow M,Hübler M,Rasche S,Albrecht M

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Cardiac surgery requiring cardiopulmonary bypass is associated with platelet activation. Because platelets are increasingly recognized as important effectors of ischemia and end-organ inflammatory injury, the authors explored whether postoperative nadir platelet counts are associated with acute kidney injury...

journal_title：Anesthesiology

authors： Kertai MD,Zhou S,Karhausen JA,Cooter M,Jooste E,Li YJ,White WD,Aronson S,Podgoreanu MV,Gaca J,Welsby IJ,Levy JH,Stafford-Smith M,Mathew JP,Fontes ML

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:A high proportion of patients having cardiac bypass surgery receive erythrocyte transfusions. Decisions about when to transfuse patients having surgery for coronary artery disease may impact on erythrocyte utilization and patient morbidity and mortality. There are no published data about the factors that inf...

journal_title：Anesthesiology

authors： Shehata N,Wilson K,Mazer CD,Tomlinson G,Streiner D,Hebert P,Naglie G

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Etomidate is a sedative hypnotic that is often used in critically ill patients because it provides superior hemodynamic stability. However, it also binds with high affinity to 11beta-hydroxylase, potently suppressing the synthesis of steroids by the adrenal gland that are necessary for survival. The authors ...

journal_title：Anesthesiology

authors： Cotten JF,Forman SA,Laha JK,Cuny GD,Husain SS,Miller KW,Nguyen HH,Kelly EW,Stewart D,Liu A,Raines DE

更新日期：2010-03-01 00:00:00

abstract：:Cognitive performance in postsurgical patients may be impaired by disturbances of normal circadian rhythm analogous to those produced by rapid transmeridian travel ("jet lag"). We therefore tested the hypothesis that isoflurane anesthesia alone produces a phase-delay in the human circadian temperature rhythm. We monit...

journal_title：Anesthesiology

authors： Sessler DI,Lee KA,McGuire J

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:The concept of the axillary "sheath" has been a central tenet of brachial plexus regional anesthesia for many years. Recent investigations have cast doubt on its nature and existence. This study further examines the issue. METHODS:Computerized axial tomographic dye studies were performed using continuous ca...

journal_title：Anesthesiology

authors： Cornish PB,Leaper C

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Propofol may produce amnesia by affecting encoding. The hypothesis that propofol weakens encoding was tested by measuring regional cerebral blood flow during verbal encoding. METHODS:Seventeen volunteer participants (12 men; aged 30.4 +/- 6.5 yr) had regional cerebral blood flow measured using H2O positron ...

journal_title：Anesthesiology

authors： Veselis RA,Pryor KO,Reinsel RA,Mehta M,Pan H,Johnson R Jr

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Postoperative nausea and vomiting continue to be a significant problem for pediatric ambulatory surgery patients. Although ondansetron has been demonstrated to be effective in the prophylactic treatment of postoperative nausea and vomiting (surrogate end point) no one has demonstrated a benefit of antiemetic...

journal_title：Anesthesiology

authors： Davis PJ,McGowan FX Jr,Landsman I,Maloney K,Hoffmann P

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Isoflurane administration is known to increase extracellular dopamine (DA) concentration. Because the dopamine transporter (DAT) is a key regulator of DA, it is likely affected by isoflurane. This study investigates the hypothesis that isoflurane inhibits DA reuptake by causing DAT to be trafficked into the ...

journal_title：Anesthesiology

authors： Votaw J,Byas-Smith M,Hua J,Voll R,Martarello L,Levey AI,Bowman FD,Goodman M

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Cerebral injury is among the most common and disabling complications of open heart surgery. Attempts to provide neuroprotection have yielded conflicting results. We assessed the potential of propofol-induced burst suppression during open heart surgery to provide cerebral protection as determined by postopera...

journal_title：Anesthesiology

authors： Roach GW,Newman MF,Murkin JM,Martzke J,Ruskin A,Li J,Guo A,Wisniewski A,Mangano DT

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Several investigations into brain activation caused by pain have suggested that the multiple painful stimulations used in typical block designs may cause attenuation over time of the signal within activated areas. The effect this may have on pain investigations using multiple tasks has not been investigated....

journal_title：Anesthesiology

authors： Ibinson JW,Small RH,Algaze A,Roberts CJ,Clark DL,Schmalbrock P

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Anesthetics are protective during ischemic-reperfusion injury and associated inflammation; therefore, the authors hypothesized that anesthetic pretreatment may provide protection in culture from cytokine-induced cell death. METHODS:Rat vascular smooth muscle (VSM) cell and human umbilical vascular endotheli...

journal_title：Anesthesiology

authors： de Klaver MJ,Manning L,Palmer LA,Rich GF

更新日期：2002-07-01 00:00:00

abstract：:To determine whether administration of nitrous oxide, 50% and 70%, could provide analgesia and anxiolysis during venous cannulation in pediatric patients, 165 ASA Physical Status 1 patients scheduled for elective surgery were studied. Children, 3 weeks to 18 yr of age, were randomly assigned either to receive nitrous ...

journal_title：Anesthesiology

authors： Henderson JM,Spence DG,Komocar LM,Bonn GE,Stenstrom RJ

更新日期：1990-02-01 00:00:00

abstract：:Ketamine is used clinically as a racemic mixture of optical isomers that differ in their analgesic properties and psychomimetic effects. Administered individually, or together as the racemate, ketamine enantiomers differ in their hepatic clearance and duration of anesthetic effect. S(+) ketamine exhibits a greater cle...

journal_title：Anesthesiology

authors： Kharasch ED,Labroo R

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:The relative contributions of intraoperative and postoperative hypotension to perioperative morbidity remain unclear. We determined the association between hypotension and a composite of 30-day myocardial infarction and death over three periods: (1) intraoperative, (2) remaining day of surgery, and (3) durin...

journal_title：Anesthesiology

authors： Sessler DI,Meyhoff CS,Zimmerman NM,Mao G,Leslie K,Vásquez SM,Balaji P,Alvarez-Garcia J,Cavalcanti AB,Parlow JL,Rahate PV,Seeberger MD,Gossetti B,Walker SA,Premchand RK,Dahl RM,Duceppe E,Rodseth R,Botto F,Devereaux P

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:We aimed to assess the clinical effectiveness of intravenous exenatide compared to insulin in perioperative blood glucose control in coronary artery bypass grafting surgery patients. METHODS:Patients more than 18 yr old admitted for elective coronary artery bypass grafting were included in a phase II/III no...

journal_title：Anesthesiology

authors： Besch G,Perrotti A,Mauny F,Puyraveau M,Baltres M,Flicoteaux G,Salomon du Mont L,Barrucand B,Samain E,Chocron S,Pili-Floury S

更新日期：2017-11-01 00:00:00

abstract：:The effects of the neodymium-yttrium aluminum garnet (Nd-YAG) laser on several commonly used endotracheal tubes were examined. Six different types of tubes were tested for flammability. Three tubes were clear, transparent polyvinylchloride with black lettering on the surface. One was yellow-green silicone rubber with ...

journal_title：Anesthesiology

authors： Geffin B,Shapshay SM,Bellack GS,Hobin K,Setzer SE

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Rocuronium, like other steroidal nondepolarizing muscle relaxants, may in part be eliminated by the liver. To determine the influence of liver disease on its neuromuscular blocking effect, we studied the pharmacokinetics and pharmacodynamics of rocuronium in patients with cirrhosis. METHODS:Eighteen patient...

journal_title：Anesthesiology

authors： Khalil M,D'Honneur G,Duvaldestin P,Slavov V,De Hys C,Gomeni R

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Volatile anesthetics relax airway smooth muscle (ASM) by altering intracellular Ca2+ concentration ([Ca2+]i). The authors hypothesized that relaxation is produced by decreasing sarcoplasmic reticulum Ca2+ content via increased Ca2+ "leak" through both inositol trisphosphate (IP3) and ryanodine receptor chann...

journal_title：Anesthesiology

authors： Pabelick CM,Prakash YS,Kannan MS,Warner DO,Sieck GC

更新日期：2001-07-01 00:00:00

abstract：:To evaluate the effect of Bicitra (Willen Drug Company, Baltimore, Maryland), a commercial preparation of sodium citrate and metoclopramide, on gastric contents 150 elective outpatients allocated into six groups with 25 patients in each group were studied. Patients in Group 1 served as controls. Patients in Groups 2, ...

journal_title：Anesthesiology

authors： Manchikanti L,Grow JB,Colliver JA,Hadley CH,Hohlbein LJ

更新日期：1985-10-01 00:00:00

abstract：:Analgesia is an important component of general anesthesia. alpha 2-adrenoceptor agonists such as clonidine and dexmedetomidine are effective analgesics at the spinal level, and furthermore, they reduce the volatile anesthetic requirement. In order to probe a possible spinal-level contribution to general anesthetic-ind...

journal_title：Anesthesiology

authors： Savola MK,Woodley SJ,Maze M,Kendig JJ

更新日期：1991-09-01 00:00:00

abstract：:There has been a dramatic growth of scholarly articles in medical education in recent years. Evaluating medical education research requires specific orientation to issues related to format and content. Our goal is to review the quantitative aspects of research in medical education so that clinicians may understand the...

journal_title：Anesthesiology

authors： Ratelle JT,Sawatsky AP,Beckman TJ

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:To assess the performance of transcranial Doppler (TCD) in predicting neurologic worsening after mild to moderate traumatic brain injury. METHODS:The authors conducted a prospective observational study across 17 sites. TCD was performed upon admission in 356 patients (Glasgow Coma Score [GCS], 9 to 15) with...

journal_title：Anesthesiology

authors： Bouzat P,Almeras L,Manhes P,Sanders L,Levrat A,David JS,Cinotti R,Chabanne R,Gloaguen A,Bobbia X,Thoret S,Oujamaa L,Bosson JL,Payen JF,Asehnoune K,Pes P,Lefrant JY,Mirek S,Albasini F,Scrimgeour C,Thouret JM,Char

更新日期：2016-08-01 00:00:00

abstract：:Hepatic drug-metabolizing enzymes and hepatic ultrastructure were studied in rats after two hours of anesthesia with 1 MAC halothane or diethyl ether. Twelve hours after cessation of either anesthetic smooth endoplasmic reticulum was increased in centrilobular but not in periportal hepatocytes. This change persisted a...

journal_title：Anesthesiology

authors： Ross WT Jr,Cardell RR Jr

更新日期：1978-05-01 00:00:00