Maternal collagen vascular disease associated with fetal heart block and degenerative changes of the atrioventricular valves.

Abstract:

:We report the case of a fetus diagnosed at 24 weeks' gestation with complete heart block associated with maternal collagen vascular disease and Sjögren's antibody. Serial fetal echocardiograms noted increased echogenicity along the tricuspid and mitral valves without insufficiency. Postnatally, severe tricuspid insufficiency occurred following placement of an endocardial pacing lead, and severe mitral insufficiency occurred acutely at 2.5 months of age. Both valves were noted at surgery to have fibrotic and calcific chordae tendineae that had ruptured from their papillary muscles. An inflammatory reaction within the fetal heart related to transplacental passage of Sjögren's antibody was likely responsible.

journal_name

Pediatr Cardiol

journal_title

Pediatric cardiology

authors

Weber HS,Myers JL

doi

10.1007/BF00800677

subject

Has Abstract

pub_date

1994-07-01 00:00:00

pages

204-6

issue

4

eissn

0172-0643

issn

1432-1971

journal_volume

15

pub_type

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