Abstract：
:Vitamin D has anti-inflammatory properties, and deficiency is prevalent in children. There is a paucity of data regarding vitamin D status and its correlation with low-grade inflammation and vasculature. We prospectively enrolled 25 children, 9-11 years old (13 male); 21 obese. Eight atherosclerosis-promoting risk factors were scored as categorical variables with the following thresholds defining abnormality: body mass index Z score ≥ 1.5; systolic blood pressure ≥ 95th percentile (for age, sex, and height); triglyceride ≥ 100 mg/dL; low-density lipoprotein cholesterol (LDL-C) ≥ 110 mg/dL; high-density lipoprotein cholesterol ≤ 45 mg/dL; hemoglobin A1C (HBA1C) ≥ 5.5; 25-hydroxyvitamin D [25(OH) D] ≤ 30 ng/mL, and tobacco smoke exposure. High-sensitivity C-reactive protein (hsCRP) was measured to assess low-grade inflammation and classified as low- (<1 mg/L), average- (1-3 mg/L), and high-risk (>3 to <10 mg/L) groups. The proportion of children within each hsCRP group who had above threshold risk factors was calculated. Carotid artery ultrasound was performed to measure carotid artery intima-media thickness (CIMT). Median (range) for 25(OH) D was 24 (17-45) ng/mL. Eighteen were either 25 (OH) D deficient (<20 ng/mL) or insufficient (20-30 ng/mL), and seven were sufficient (>30 ng/mL). hsCRP was 1.7 (0.2-9.1) mg/L, with 11 being <1.0 mg/L, 8 between 1.0-3.0 and 6 > 3.0 to < 10.0 mg/L. Risk factor score was 3.9 ± 1.7 out of eight. 25(OH) D levels did not correlate with hsCRP or CIMT. While vitamin D deficiency, inflammation, and risk factors coexist at a very young age, causative mechanisms remain unclear.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Singh J,Merrill ED,Sandesara PB,Schoeneberg L,Dai H,Raghuveer Gdoi
10.1007/s00246-015-1162-0subject
Has Abstractpub_date
2015-10-01 00:00:00pages
1338-43issue
7eissn
0172-0643issn
1432-1971pii
10.1007/s00246-015-1162-0journal_volume
36pub_type
杂志文章abstract：:A 10-month-old boy was referred for tachypnea and heart murmur. An echocardiogram showed unexplained left heart dilation without evidence of an intracardiac shunt. A 64-slice computed tomographic contrast-enhanced angiography showed a large tortuous anomalous artery arising from the descending thoracic aorta and suppl...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-008-9287-z
更新日期：2009-01-01 00:00:00
abstract：:We report a rare case of tetralogy of Fallot with total anomalous pulmonary venous return, left heart hypoplasia, right lung hypoplasia, and left ocular-mandibular synchinesia (Marcus-Gunn phenomenon), correctly diagnosed by cardiovascular magnetic resonance imaging and successfully operated by modified Glenn anastomo...
journal_title：Pediatric cardiology
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doi：10.1007/s00246-004-0769-3
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doi：10.1007/s00246-020-02352-9
更新日期：2020-06-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900222
更新日期：1997-11-01 00:00:00
abstract：:In our institute, 1100 patients with a history of Kawasaki disease have been catheterized for selective coronary arteriography. Their age at examination ranged from four months to 13 years. Coronary artery lesions (CAL) were found in 262 patients. As far as the type of the CAL was concerned, occlusion was noted in 20 ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02315475
更新日期：1986-01-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02239576
更新日期：1990-04-01 00:00:00
abstract：:A 6-year-old girl presented with respiratory distress. Chest radiographs exhibited calcifications in the mediastinum. Further imaging revealed extensive cardiac calcifications on computed tomography of the chest. The laboratory parameters were consistent with findings of secondary hyperparathyroidism. Detailed review ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-004-0765-7
更新日期：2005-07-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9409-2
更新日期：2009-07-01 00:00:00
abstract：:We describe the first report of an infant who was born with hypoplastic left heart syndrome and significant pulmonary stenosis. He was successfully palliated with multiple cardiac catheterization interventions while waiting for cardiac transplantation. This unusual constellation of heart defects is an entity that is r...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-004-0856-5
更新日期：2005-09-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1456-x
更新日期：2016-12-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900446
更新日期：1999-05-01 00:00:00
abstract：:Aortic atresia and interrupted aortic arch is a rare cardiac combination. Review of the literature revealed nine cases. We present two patients with this combination and the additional finding of quadricuspid pulmonary valves, one of which was severely stenotic. In the latter patient, an aortopulmonary window was pres...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-004-0754-x
更新日期：2005-07-01 00:00:00
abstract：:The current pulse-oximetry screening (POS) protocol for detection of critical congenital heart defects (CCHDs) is recommended only for newborns in well-infant and intermediate care nurseries, and there is no evidence-based protocol for infants discharged from the neonatal intensive care unit (NICU). The objectives of ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0793-2
更新日期：2014-03-01 00:00:00
abstract：:Information and communication technology has been widely applied to various fields, including clinical medicine. We report here a telediagnosis system using ultrasound image transmission. The effect of telediagnosis, using a medical link between local maternity hospitals and our children's medical center, was verified...
journal_title：Pediatric cardiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00246-013-0834-x
更新日期：2014-04-01 00:00:00
abstract：:Maintaining patency of the ductus arteriosus pending surgical intervention can be critical to the survival of the neonate with ductal dependent congenital heart disease. Spontaneously delayed ductal closure has been observed clinically and experimentally in newborns with critical pulmonic stenosis. Infants with ductal...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02263445
更新日期：1987-01-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0224-9
更新日期：2012-06-01 00:00:00
abstract：:Use of extracorporeal membrane oxygenation (ECMO) in infants with congenital heart disease is becoming more frequent. We present the first reported use of balloon atrial septostomy during ECMO support and describe possible complications of such procedures unique to ECMO therapy. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00795647
更新日期：1993-07-01 00:00:00
abstract：:Acute myopericarditis is a major cause of acquired heart disease worldwide in pediatric patients. Various viruses have been reported as the etiology, of which varicella zoster virus was first reported in 1953. However, since nationwide administration of the varicella vaccine, reports of varicella-associated myopericar...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9637-5
更新日期：2010-07-01 00:00:00
abstract：:Accessory atrioventricular pathways (AP) are the most common substrate for paroxysmal supraventricular tachycardia in infants and small children. Up-to-date data on AP ablation in infants and small children are limited. The aim of the present study was to gain additional insight into radiofrequency (RF) catheter ablat...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1365-z
更新日期：2016-06-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
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更新日期：2009-10-01 00:00:00
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doi：10.1007/s00246-011-9948-1
更新日期：2011-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：1984-07-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010154
更新日期：2001-01-01 00:00:00
abstract：:The response to warfarin is highly variable among individuals and such variability is likely to have some genetic basis. We evaluted the effect of VKORC1 polymorphisms on warfarin response among Japanese, taking advantage of its unique population structure in which CYP2C9 *2 and *3 alleles are relatively rare. Thirty-...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-005-1150-x
更新日期：2006-11-01 00:00:00
abstract：:Children with trisomy 21 have a high incidence of congenital heart disease that frequently requires surgical repair. These patients often require multiple and higher dosage sedatives during the postoperative period. Dexmedetomidine is an alpha(2)-adrenergic receptor agonist that has sedative, analgesic, and anxiolytic...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-006-0072-6
更新日期：2007-09-01 00:00:00
abstract：:Cardiac rhabdomyoma (CR) is the most common cardiac tumor in newborns. Approximately 75% of cases are associated with tuberous sclerosis complex. Although these tumors usually spontaneously regress after 2 years of age, they can be life-threatening when they obstruct major cardiac inflow or outflow pathways. Everolimu...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-017-1688-4
更新日期：2017-10-01 00:00:00
abstract：:Antenatal diagnosis of right heart enlargement has a wide spectrum of differential diagnosis from maternal, placental and fetal causes, and outcomes of all are not known. Coarctation of the aorta is in the differential diagnosis of right heart enlargement. In our study, we focused to measure multiple cardiac dimension...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1168-7
更新日期：2015-10-01 00:00:00
abstract：:Right ventricular (RV) function as assessed by deformation has been evaluated prenatally and after palliation in hypoplastic left heart syndrome (HLHS). However, limited data exist about the immediate postnatal cardiac adaptation and RV function in HLHS. We compared echocardiographic measures of cardiac performance in...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1974-9
更新日期：2019-01-01 00:00:00
abstract：:The data on the outcomes of children with heart disease and Down syndrome receiving extracorporeal membrane oxygenation (ECMO) for cardiac or respiratory failure are limited. This study aimed to evaluate morbidity and mortality associated with ECMO in children with Down syndrome and heart disease. Children younger tha...
journal_title：Pediatric cardiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00246-014-0945-z
更新日期：2014-12-01 00:00:00
abstract：:Limited data exist on the impact of prenatal diagnosis and outcomes of fetal truncus arteriosus (TA). We sought to assess prenatal diagnostic accuracy and prenatal outcomes in fetuses with TA and compare postnatal outcomes in neonates with prenatally and postnatally diagnosed TA. Records were reviewed for patients dia...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-008-9328-7
更新日期：2009-04-01 00:00:00
