Reactions of immune sera against the nucleocapsid, envelope and whole herpes simplex virus type 1.

Abstract:

:Antibodies against (a) naked particles, (b) virus envelope, and (c) whole herpes simplex virus (HSV) type 1 were investigated. Immune rabbit serum against naked particles (and formalized naked particles) contained virus neutralizing (VN) antibody in a low titre as compared to the titre of complement-fixing (CF) antibody. Immune rabbit serum against the viral envelope had similar titres of VN and CF antibodies. In gel double diffusion precipitation tests, whole HSV gave two precipitation zones with antibodies against naked particles two zones with antibodies against the virus envelope, several zones with antibodies against whole virus and two marked zones against human convalescent serum. Viral nucleocapsid reacted with two zones with antibodies against the nucleocapsid and a faint zone with antibodies against the virus envelope. The envelopes gave two zones with antibodies against whole virus and a faint zone with antibodies against naked particles. Human convalescent serum gave a single precipitation zone with viral nucleocapsid and two zones with virus envelope and whole virus.

journal_name

Acta Virol

journal_title

Acta virologica

authors

Lesso J,Hána L,Matis J

subject

Has Abstract

pub_date

1976-02-01 00:00:00

pages

48-52

issue

1

eissn

0001-723X

issn

1336-2305

journal_volume

20

pub_type

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