Treatment of necrobiosis lipoidica diabeticorum by hyperbaric oxygen.

Abstract:

:Necrobiosis lipoidica diabeticorum is a chronic cutaneous complication of diabetes mellitus with microangiopathy as an important pathophysiologic factor. Because of the known success of hyperbaric oxygen in the treatment of chronic non-healing wounds, we used this mode of therapy to treat a diabetic patient with ulcerated necrobiosis lipoidica of 7 years' duration, refractory to medical and surgical treatment. The patient received daily sessions of hyperbaric oxygen therapy. There was considerable improvement during the course of the treatment, with complete closure of all the ulcerations after 98 sessions. The success of this treatment emphasizes the role of hypoxia in the pathogenesis of the lesion. This simple and safe treatment method may be a good solution for patients with chronic nonhealing necrobiosis lipoidica which fails to respond to other therapeutic approaches.

journal_name

Acta Derm Venereol

authors

Weisz G,Ramon Y,Waisman D,Melamed Y

doi

10.2340/0001555573447448

subject

Has Abstract

pub_date

1993-12-01 00:00:00

pages

447-8

issue

6

eissn

0001-5555

issn

1651-2057

journal_volume

73

pub_type

临床试验,杂志文章
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  • Assessment of atrophy of human skin caused by corticosteroids using chamber occlusion and suction blister techniques.

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  • Paired Basic Amino Acid-cleaving Enzyme 4 (PCSK6): An Emerging New Target Molecule in Human Melanoma.

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    pub_type: 杂志文章,多中心研究

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    doi:

    authors: Flindt-Hansen H,McFadden N,Eeg-Larsen T,Thune P

    更新日期:1991-01-01 00:00:00

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    pub_type: 杂志文章

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  • Incontinentia pigmenti achromians (Ito).

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  • Out-of-pocket Costs for Individuals with Atopic Eczema: A Cross-sectional Study in Nine European Countries.

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    pub_type: 杂志文章

    doi:

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    更新日期:1980-01-01 00:00:00

  • The functions of polymorphonuclear leukocytes emigrating into the skin.

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    pub_type: 杂志文章

    doi:

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    pub_type: 杂志文章

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    更新日期:1979-01-01 00:00:00

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