Assessment of atrophy of human skin caused by corticosteroids using chamber occlusion and suction blister techniques.

Abstract:

:The effect of five corticosteroid ointments on epidermal thickness was studied using occlusive chamber application. Thinning of the epidermis and telangiectasia were noted 3 weeks after application of betamethasone-17-valerate (BV), budesonide (BD), clobetasol-17-propionate (CP), and fluocinolone acetonide (FA), but not of hydrocortisone (HC). Suction blisters were raised at the treated sites. Epidermal thinning was always associated with reduction in cell number. By combining different methods it seems possible to define more precisely the epidermal effects of various corticosteroid preparation.

journal_name

Acta Derm Venereol

authors

Somerma S,Lassus A,Salde L

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

41-5

issue

1

eissn

0001-5555

issn

1651-2057

journal_volume

64

pub_type

杂志文章
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    doi:

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    doi:

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  • Bestatin therapy of patients with atopic dermatitis.

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    doi:

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