Pachyonychia congenita Jadassohn-Lewandowsky: a disorder of keratinization.

abstract：:Dermal cells maintained in cultured human skin explants for up to 10 weeks were studied by electron microscopy. Common findings in the cell organelles were: 1) altered nuclear shapes and numerous nuclear bodies; 2) reduced rough endoplasmic reticulum; 3) a prominent Golgi complex; and 4) an increasing number of free r...

journal_title：Acta dermato-venereologica

authors： Hentzer B,Kobayasi T

更新日期：1980-01-01 00:00:00

abstract：:Homogenates of irradiated and non-irradiated skin from 16 patients with chronic polymorphous light eruptions (CPLE) were examined to detect possible light-induced antigen to cell-mediated immunity. The leukocyte migration agarose tests which were performed disclosed no evidence of migration inhibition in either type o...

journal_title：Acta dermato-venereologica

authors： Jansén CT,Helander I

更新日期：1976-01-01 00:00:00

abstract：:Eye colour, hair colour and skin colour are important risk factors for malignant melanoma and non-melanoma skin cancers. There are few studies in which the distribution of these pigmentary factors in risk populations has been assessed. The purpose of this study was to investigate the prevalence of the major eye and ha...

journal_title：Acta dermato-venereologica

authors： Lock-Andersen J,Wulf HC,Knudstorp ND

更新日期：1998-05-01 00:00:00

abstract：:In 13 patients with contact allergy to sesame oil, studies were undertaken to elucidate the nature of the allergens. Sesamol, sesamin and sesamolin were identified in crude and purified (pharmaceutical) sesame oil. Patch tests showed 8 of the 13 patients to be positive to sesamol and 12 to sesamolin and sesamin. Patch...

journal_title：Acta dermato-venereologica

authors： Neering H,Vitányi BE,Malten KE,van Ketel WG,van Dijk E

更新日期：1975-01-01 00:00:00

abstract：:We evaluated the reproducibility of atopy patch test reactions and the quality and quantity of itch in 16 patients with atopic eczema and a history of a positive atopy patch test reaction, comparing three different application sites. The allergen was re-applied simultaneously on both forearms and the back. Intensity a...

journal_title：Acta dermato-venereologica

authors： Weissenbacher S,Bacon T,Targett D,Behrendt H,Ring J,Darsow U

更新日期：2005-01-01 00:00:00

abstract：:In patients with atopic dermatitis the skin is highly susceptible to infection by bacteria, fungi and viruses. Increasing knowledge about the complex immune network that regulates anti-microbial responses has helped to dissect further the role of infections in atopic dermatitis. Conserved patterns of microbes are reco...

journal_title：Acta dermato-venereologica

authors： Biedermann T

更新日期：2006-01-01 00:00:00

abstract：:The expression of Fc-IgG receptors on mononuclear phagocytes (monocytes/macrophages), as well as the activity of soluble immune suppressor supernatant of T-cell proliferation (SISS-T) factor have been investigated in 23 patients with squamous cell carcinoma (SCC) of the lower lip, including 8 patients with metastases ...

journal_title：Acta dermato-venereologica

authors： Vena GA,Angelini G,D'Ovidio R,Pastore A,Meneghini CL

更新日期：1983-01-01 00:00:00

abstract：:Using the mouse, photoallergy to the antiarrhythmic agent quinidine could be induced following systemic administration. After pretreatment with cyclophosphamide 150 mg/kg, groups of 5-10 mice were injected i.p. with quinidine chloride 100 mg/kg on 2 consecutive days, followed by exposure of shaved abdominal skin to UV...

journal_title：Acta dermato-venereologica

authors： Wirestrand LE,Ljunggren B

更新日期：1988-01-01 00:00:00

abstract：:Data regarding the efficacy and safety of methotrexate (MTX) in adults with localized scleroderma (LoS) is scarce. This study gathered data from a retrospective cohort of adult patients with LoS (n?=?107), treated with MTX (1993-2015). MTX drug survival and predictors thereof were analysed. After 1 and 2 years, 26% an...

journal_title：Acta dermato-venereologica

authors： Mertens JS,van den Reek JM,Kievit W,van de Kerkhof PC,Thurlings RM,Radstake TR,Seyger MM,de Jong EM

更新日期：2016-11-02 00:00:00

abstract：:The main aims of this cross-sectional study were: (i) to assess the frequency of genital (vulval) lichen planus (VLP) and vulval lichen sclerosus (VLS) in women affected with oral lichen planus (OLP), regardless of the genital symptoms reported; and (ii) to verify whether any demographic, clinical, or histological fea...

journal_title：Acta dermato-venereologica

authors： Di Fede O,Belfiore P,Cabibi D,De Cantis S,Maresi E,Kerr AR,Campisi G

更新日期：2006-01-01 00:00:00

abstract：:Four patients with classic recalcitrant prurigo nodularis had symptomatic and physical responses to thalidomide with remissions. Three of the four patients had increased IgE levels that decreased during therapy. In two patients, short-term treatment (2 to 3 months) was not sufficient to produce remission, but retreatm...

journal_title：Acta dermato-venereologica

authors： Winkelmann RK,Connolly SM,Doyle JA,Padilha-Goncalves A

更新日期：1984-01-01 00:00:00

abstract：:Alexithymia, defined as difficulty in describing or recognizing emotions, has been shown to be connected with psoriasis, but its relationship with self-management of psoriasis has not been explored. The aim of this study was to assess the frequency of alexithymia and its relationship with self-management and illness p...

journal_title：Acta dermato-venereologica

authors： Larsen MH,Krogstad AL,Wahl AK

更新日期：2017-08-31 00:00:00

abstract：:A leukoplakic lesion of the prepuce is described with the histologic and ultrastructural features of epidermolytic hyperkeratosis. The lesion represents most likely a variant of epidermolytic leukoplakia recently observed in the vermilion border of the lip. ...

journal_title：Acta dermato-venereologica

authors： Kolde G,Vakilzadeh F

更新日期：1983-01-01 00:00:00

abstract：:The aromatic retinoids etretinate and acitretin are widely used in the systemic treatment of severe psoriasis. The purpose of the present investigation was to further elucidate the mode of action of acitretin on abnormal keratinization and epidermal hyperproliferation in an in vivo model. Studies on the interference o...

journal_title：Acta dermato-venereologica

authors： Gerritsen MJ,van Pelt JP,van de Kerkhof PC

更新日期：1996-01-01 00:00:00

abstract：:The skin absorption of clioquinol and chloroquinaldol in ointment or cream base was studied in fourteen patients with widespread dermatoses. A serum concentration in the range of 0.3--1.3 microgram/ml using clioquinol and 0.05--0.1 microgram/ml with chloroquinaldol was reached by the second day and persisted throughou...

journal_title：Acta dermato-venereologica

authors： Fischer T,Fagerlund C,Hartvig P

更新日期：1978-01-01 00:00:00

abstract：:We report a 69-year-old man with severe generalized morphea, who showed over 80% of skin involvement, while the internal organs were not affected. We performed histological examinations and analysis of skin disaccharides constituting chondroitinase-digestible glycosaminoglycans in the center and periphery of the scler...

journal_title：Acta dermato-venereologica

authors： Akimoto S,Ishikawa O,Yokoyama Y,Amano H,Miyachi Y

更新日期：1996-03-01 00:00:00

abstract：:A 31-year-old woman developed typical clinical and laboratory signs of PCT at the end of her second pregnancy coincident with the summer season. She had elevated liver function values without history of alcoholism, hepatitis or chemical liver damage. She had taken oral contraceptive only before her first pregnancy whi...

journal_title：Acta dermato-venereologica

authors： Rajka G

更新日期：1984-01-01 00:00:00

abstract：:Psoriasin, which is highly expressed in psoriasis, is encoded by a gene located within the epidermal differentiation complex. The aim of this study was to investigate the effect of endogenous psoriasin on disturbed keratinocyte differentiation in psoriasis. Immunohistochemical staining revealed a gradient of psoriasin...

journal_title：Acta dermato-venereologica

authors： Ekman AK,Vegfors J,Eding CB,Enerbäck C

更新日期：2017-04-06 00:00:00

abstract：:The association between itch and suicidal ideation has not been explored previously in the general population. The aim of the present study is to analyse the association between itch and suicidal ideation in adolescents, and to compare the findings with an expected association between pain and suicidal ideation in the...

journal_title：Acta dermato-venereologica

authors： Halvorsen JA,Dalgard F,Thoresen M,Bjertness E,Lien L

更新日期：2012-09-01 00:00:00

abstract：:The effect of a protective cream was tested in a new tandem repeated irritation test with tandem application of 0.5% sodium lauryl sulphate (SLS) and undiluted toluene. The irritants were applied twice daily for 30 min to the ventral forearms of 20 volunteers. Irritant cutaneous reactions were quantified by a visual s...

journal_title：Acta dermato-venereologica

authors： Wigger-Alberti W,Spoo J,Schliemann-Willers S,Klotz A,Elsner P

更新日期：2002-01-01 00:00:00

abstract：:is missing (Short communication). ...

journal_title：Acta dermato-venereologica

authors： Macaux L,Zemali N,Jaubert J,Koumar Y,Manaquin R,Poubeau P,Camuset G,Gérardin P,Bertolotti A

更新日期：2020-11-04 00:00:00

abstract：:Blood levels of serotonin (5-HT) and urinary excretion of 5-hydroxyindole-acetic acid (5-HIAA), tryptamine (T), and indole-acetic acid (IAA) were determined in 39 cases of systemic scleroderma and in 7 cases of very severe cutaneous scleroderma. The T/IAA ratio was normal and serotonin elevated in mild and rather seve...

journal_title：Acta dermato-venereologica

authors： Stachów A,Jabłońska S,Skiendzielewska A

更新日期：1979-01-01 00:00:00

abstract：:Digitonin, which is known to cause extensive damage to cytomembranes in general, was found to have a most remarkable effect on epidermal Langerhans' cells. Thus, it generates a membrane-sandwiching process resulting in the formation of large discs which except for the differences in size have the same morphology as or...

journal_title：Acta dermato-venereologica

authors： Bartosik J,Andersson A,Axelsson S,Falck B,Ringberg A

更新日期：1985-01-01 00:00:00

abstract：:Having observed altered itch and flare reactions after histamine application in patients with atopic eczema, we tried to determine these reactions in patients with urticaria and psoriasis. We investigated 16 healthy non-atopic subjects, 16 atopics in an eczema-free interval, 16 with acute atopic eczema, 16 with urtica...

journal_title：Acta dermato-venereologica

authors： Heyer G,Koppert W,Martus P,Handwerker HO

更新日期：1998-03-01 00:00:00

abstract：:We report 3 cases of pruriginous papular eruption of HIV disease, in which demodectic mites were found in the pilosebaceous follicles which were surrounded by a granulomatous inflammatory infiltrate. Papular eruption of HIV disease is a distinctive clinicopathological entity, whose pathogenicity is not known. Our obse...

journal_title：Acta dermato-venereologica

authors： Bodokh I,Lacour JP,Perrin C,Bourdet JF,Ortonne JP

更新日期：1994-07-01 00:00:00

abstract：:Lymphocytotoxic autoantibody (LCTA) was studied in 9 patients with active pemphigus and 19 patients with active systemic lupus erythematosus (SLE). All patients with SLE showed high titres of LCTA but only one patient with pemphigus had LCTA. In this paper we discuss the immunological significance of LCTA and the diff...

journal_title：Acta dermato-venereologica

authors： Furukawa F,Imamura S,Inoue S,Yoshida H,Hamashima Y

更新日期：1982-01-01 00:00:00

abstract：:We describe a case of gingival hyperplasia in a 36-year-old renal transplantation recipient treated with nifedipine for severe arterial hypertension. The appearance of the gingival disorder was probably related to nifedipine intake. Histologically, in addition to the findings of acanthosis, papillomatosis and connecti...

journal_title：Acta dermato-venereologica

authors： Bencini PL,Crosti C,Sala F,Montagnino G,Tarantino A,Menni S,Piccinno R

更新日期：1985-01-01 00:00:00

abstract：:The prevalence of melanocytic naevi in children correlates with sun exposure and may serve as an objective population risk indicator of future melanoma incidence. The aim was to investigate if mobile teledermatology could offer a valid methodology compared with standard manual, face-to-face counting of naevi on the ba...

journal_title：Acta dermato-venereologica

authors： Karlsson MA,Lindelöf B,Wahlgren CF,Wiklund K,Rodvall Y

更新日期：2015-03-01 00:00:00

abstract：:Radiological examination of the hands was performed in 41 patients with systemic sclerosis. Pathological changes were found in 39 patients. Eighteen patients had subcutaneous calcifications and 11 had atrophy of the finger pulps. Bone resorption of ungual tufts was found in 11 patients. Juxta-articular osteoporosis wa...

journal_title：Acta dermato-venereologica

authors： Brun B,Serup J,Hagdrup H

更新日期：1983-01-01 00:00:00

abstract：:We present a 32-year-old white patient with congenital reticular ichthyosiform erythroderma, also known as ichthyosis variegata. The patient had typical clinical features with areas of normal appearing skin surrounded by erythematous hyperkeratotic patches. The smaller "confetti-like" patches were mostly present on th...

journal_title：Acta dermato-venereologica

authors： Krunic AL,Palcesky D,Busbey S,Medenica M

更新日期：2003-01-01 00:00:00