Drug eruptions: causative agents and clinical types. A series of in-patients during a 10-year period.

Abstract:

:A series of 446 inpatients with drug eruption was studied to determine the causative agent and the clinical type. In over a half of the cases a provocation test confirmed the drug responsible for the reaction. Sulphonamides/trimethoprim and ampicillin/penicillin followed by phenazones were the most frequent agents causing eruptions. Sulphonamides were also the most common drugs inducing Lyell's and Stevens-Johnson syndromes. Phenazones and barbiturates were the main causes of fixed eruptions. The frequency of inpatients having drug eruption was decreased in the 1971-80 series compared with the earlier one from 1961-70. Also the frequency of Lyell's and Stevens-Johnson syndromes was lower in the latter decade than in the earlier one.

journal_name

Acta Derm Venereol

authors

Kauppinen K,Stubb S

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

320-4

issue

4

eissn

0001-5555

issn

1651-2057

journal_volume

64

pub_type

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