Abstract:
:The validity of Laser Doppler Flowmetry for measurements of changes in skin blood flow rates during orthostatic manoeuvres was evaluated. Fifteen healthy subjects were investigated. Relative skin blood flow rates on the dorsum of the hand were measured during stepwise raising and lowering of the arm in 10 cm increments to an extreme position of 40 cm below respectively above heart level. All measurements at test levels were preceded and followed by measurements at reference level, i.e. heart level. At all levels of arm elevation, relative blood flow rates were significantly increased compared with the corresponding reference level (p = 0.0005). This was unexpected in view of the auto-regulatory mechanism. Highly significant blood flow rate reductions were found at all levels of arm lowering. This is in contrast to previous findings of unchanged skin blood flow rate to a point of approximately 35 cm below heart level, where the veno-arteriolar reflex is elicited.
journal_name
Acta Derm Venereoljournal_title
Acta dermato-venereologicaauthors
Petersen LJ,Sindrup JHdoi
102340/0001555570144147subject
Has Abstractpub_date
1990-01-01 00:00:00pages
144-7issue
2eissn
0001-5555issn
1651-2057journal_volume
70pub_type
杂志文章abstract::Patients with palpebral cellulitis may turn in the first place to a skin clinic. The clinical picture and the course of disease are illustrated here by four case histories. The importance of differentiating between collateral orbital edema, palpebral cellulitis and orbital cellulitis is stressed. ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::Familial progressive hyperpigmentation is rarely described in the literature. We report on five patients from three different families presenting with a peculiar progressive pigmentary disorder. The patients show a progressive diffuse, partly blotchy, hyperpigmentation, intermixed with scattered small hypopigmented ma...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.1080/00015550310005780
更新日期:2004-01-01 00:00:00
abstract::Phototherapy with ultraviolet (UV) radiation of wavelengths between 280 and 320 nm (UVB) is a safe and effective treatment for a variety of diseases. In addition to standard broadband UVB (bUVB), narrowband phototherapy with fluorescent bulbs emitting near monochromatic UV around 311 nm (nUVB) has become an important ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章,评审
doi:10.1080/00015550510025579
更新日期:2005-01-01 00:00:00
abstract::Tobacco smoke and UV radiation are extrinsic risk factors for accelerated skin ageing. In this study the effects of smoking on wrinkling and ageing were assessed in males living in Northern Finland, where cumulative sun exposure is low. Smoking habits, age and facial wrinkling were estimated from facial photographs of...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.1080/00015550410014969
更新日期:2004-01-01 00:00:00
abstract::Herpes simplex virus (HSV) infection is a possible pathogenic factor in Behçet's disease (BD). Using proteomics analysis, this study detected a target HSV protein. Serum IgA and IgG reactivities against the identified protein were evaluated in patients with BD and in BD-like mice. A total of 4 protein bands generated ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-2127
更新日期:2015-11-01 00:00:00
abstract::Age and sex have been identified as predictors of outcome in malignant melanoma (MM). This aim of this multicentre, cross-sectional study was to analyse the role of age and sex as explanatory variables for the diagnosis of thin MM. A total of 2430 patients with MM were recruited. Cases of in situ-T1 MM were more frequ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章,多中心研究
doi:10.2340/00015555-2115
更新日期:2015-11-01 00:00:00
abstract::Necrobiosis lipoidica diabeticorum is a chronic cutaneous complication of diabetes mellitus with microangiopathy as an important pathophysiologic factor. Because of the known success of hyperbaric oxygen in the treatment of chronic non-healing wounds, we used this mode of therapy to treat a diabetic patient with ulcer...
journal_title:Acta dermato-venereologica
pub_type: 临床试验,杂志文章
doi:10.2340/0001555573447448
更新日期:1993-12-01 00:00:00
abstract::Ciprofloxacin (CPFX) is a widely used fluoroquinolone antibiotic, inducing cutaneous adverse drug reactions in about 1 to 2% of the treated patients. Conclusive diagnosis of drug allergy, however, still remains a major problem in daily clinical practice. Here, we present 2 patients with drug allergy to CPFX. In both c...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/0001555577285288
更新日期:1997-07-01 00:00:00
abstract::A dermatitis occurring during the treatment of mycosis fungoides with A vitamin analogues (13-cis-retinoic acid and etretinate) and mimicking a progression of the disease is described. It is considered to be a skin reaction due to the treatment. Its benign nature is revealed by histology showing a lymphocytic infiltra...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::In a prospective study of 63 patients with long-lasting hand eczema, a diagnosis of atopic dermatitis could be established in 49%. Comparison between patients with atopic dermatitis and those without atopic dermatitis showed that the hand eczema pattern differed very little between the groups. Hyperlinearity was signi...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::Atopic dermatitis (AD) is a common disease in childhood and an important risk factor for the later development of other atopic diseases. Many publications on childhood AD use questionnaires based on information obtained in adulthood, which introduce the possibility of recall bias. In a prospective cohort study, recall...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-2128
更新日期:2015-11-01 00:00:00
abstract::Four patients with classic recalcitrant prurigo nodularis had symptomatic and physical responses to thalidomide with remissions. Three of the four patients had increased IgE levels that decreased during therapy. In two patients, short-term treatment (2 to 3 months) was not sufficient to produce remission, but retreatm...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::A case of prolonged gonococcal speticemia is presented. Lack of genital symptoms, of demonstrable gonococcal antibodies in whole serum, and initially also of skin lesions contributed to a delayed diagnosis that was finally confirmed by positive blood culture. Evidence of circulating immune complexes was obtained by th...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::Atopic dermatitis is a multifactorial disorder probably caused by environmental factors in combination with susceptibility genes. The clinical similarity between atopic dermatitis and the eczema manifestation in patients with Wiskott-Aldrich syndrome made the previously identified WAS gene in chromosome sub-band Xpl 1...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.1080/000155501317140043
更新日期:2001-10-01 00:00:00
abstract::Skin microdialysis is an established method for in vivo sample collection from the extracellular fluid space. This method has been extensively used in studies of inflammatory reactions in the skin of animals and humans. Skin microdialysis consists of the implantation of semi-permeable probes into the upper dermis, per...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章,评审
doi:10.2340/00015555-1878
更新日期:2014-09-01 00:00:00
abstract::The anti-inflammatory mechanisms of minocycline, an antibiotic used in the treatment of the inflammatory component of acne, are only partially understood. In addition to inflammation due to cytokines (IL-1, IL-6, TNF-alpha, etc.), recent studies have shown that neuropeptide-mediated neurogenic inflammation may play an...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.1080/000155599750010625
更新日期:1999-07-01 00:00:00
abstract::Patients with rheumatoid arthritis were investigated for contact allergy to gold in connection with treatment with gold preparations. There were 57 patients with rheumatoid arthritis previously treated with gold, with or without cutaneous side-effects, as well as 20 patients intended for such treatment; all were expos...
journal_title:Acta dermato-venereologica
pub_type: 临床试验,杂志文章
doi:10.2340/0001555577370373
更新日期:1997-09-01 00:00:00
abstract::Bullous pemphigoid is an autoimmune subepithelial disease characterised by pruritus followed by urticarial plaques and finally bullae on the skin and mucosa. Drug-associated bullous pemphigoid (DABP) is a term used to describe instances of bullous pemphigoid demonstrating clinical, histological, or immunopathological ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-3457
更新日期:2020-08-17 00:00:00
abstract::Patients with atopic dermatitis were found to have an about 7-fold increased spontaneous proliferative response of peripheral blood lymphocytes and an about 4-fold elevation of CD3-dependent lymphocyte transformation as compared to normal controls. The CD3-dependent lymphocyte response in patients with severe atopic d...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/0001555575353356
更新日期:1995-09-01 00:00:00
abstract::Peripheral blood lymphocytes from 45 patients with a positive patch test to cobalt chloride (CoCl2) and 37 controls were stimulated with various concentrations of CoCl2 and/or cobalt sulphate (CoSO4) or cobalt nitrate (Co(NO3)2) or cobalt acetate [CH3COO)2Co) for various days in culture. Lymphocytes from 35 of these p...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::EMLA cream, which is used to provide analgesia prior to venepuncture, induces a skin-blanching reaction. This reaction may be caused by both skin hydration and vasoconstriction. Twenty healthy children with veins suitable for venepuncture on the dorsa of the hands or at the antecubital fossae had applied either EMLA c...
journal_title:Acta dermato-venereologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/000155500459268
更新日期:2000-09-01 00:00:00
abstract::Disutility reflects the disability caused by a disease. The EuroQoL-5D (EQ-5D) questionnaire is a measure of health-related overall utility. The questionnaire has only been applied previously to a small number of patients with hidradenitis. In this study a survey of 421 patients with hidradenitis suppurativa was condu...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-2129
更新日期:2016-02-01 00:00:00
abstract::Lower-limb ulcers in systemic sclerosis patients are rarely reported. The aim of this study was to describe the main causes and outcomes of lower-limb ulcers in systemic sclerosis patients and to assess factors associated with ischaemic causes (arterial disease and/or microvascular impairment). A retrospective, multic...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章,多中心研究
doi:10.2340/00015555-2939
更新日期:2018-07-11 00:00:00
abstract::A case is presented of elastosis perforans serpiginosa (EPS) with unilateral dermal lesions, widespread arterial lesions with aortic rupture, and elastosis of the endocardium and bronchiolar walls. Other chronic skin disorders with lesions resembling EPS are discussed; and the arterial lesions compared with some arter...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract::Patients with suspected cutaneous adverse drug reactions are often referred to allergy clinics or departments of dermatology for evaluation. These patients are selected compared with patients identified in prospective and cross-sectional studies of hospital populations. This explains the observed variation in prevalen...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-0153
更新日期:2006-01-01 00:00:00
abstract::Lymphocytotoxic autoantibody (LCTA) was studied in 9 patients with active pemphigus and 19 patients with active systemic lupus erythematosus (SLE). All patients with SLE showed high titres of LCTA but only one patient with pemphigus had LCTA. In this paper we discuss the immunological significance of LCTA and the diff...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::The expected 4-week cure rate after conventional treatment of bacterial vaginosis are only 65-70%. In an attempt to improve the cure rate by adding probiotic lactobacilli we performed a double-blind placebo-controlled study of adjuvant lactobacilli treatment after an open treatment with vaginal clindamycin ovules. Wom...
journal_title:Acta dermato-venereologica
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1080/00015550410022249
更新日期:2005-01-01 00:00:00
abstract::Twenty-six patients with chronic dermatophytosis (CD) by Trichophyton rubrum (TR) through one year were included in a double-blind clinical trial with Levamisole/Placebo. All patients were treated with griseofulvin concomitantly. Before, during and after the trial, studies of the cellular and humoral immune response w...
journal_title:Acta dermato-venereologica
pub_type: 临床试验,杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Although recent therapeutic developments raise hope, melanoma remains a devastating disease with a need for new treatment targets. In other tumours prohormone convertases have been shown to be pro-tumourigenic as they are involved in processing preforms of matrix-metalloproteinases, growth factors and adhesion molecul...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-3525
更新日期:2020-05-28 00:00:00
abstract::is missing (Short communication). ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-2725
更新日期:2017-10-02 00:00:00