Rapid assay of the anti-inflammatory activity of topical corticosteroids by inhibition of a UVA-induced neutrophil infiltration in hairless mouse skin. II. Assessment of name brand versus generic potency.

Abstract:

:The hairless mouse model of a UVA-induced dermal neutrophilic infiltrate was used to compare the efficacy of equal concentrations of name brand versus generic corticosteroids. The generic brand was significantly less effective in suppressing the inflammatory response.

journal_name

Acta Derm Venereol

authors

Kligman LH

doi

10.2340/00015555741819

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

18-9

issue

1

eissn

0001-5555

issn

1651-2057

journal_volume

74

pub_type

杂志文章
  • Palmoplantar lesions in psoriasis: a study of 3065 patients.

    abstract::Although palmoplantar psoriasis can be severely disabling, there are very few large clinico-epidemiological studies on this condition. Our purpose was to study the morphology and pattern of lesions in Indian patients with palmoplantar psoriasis and to elucidate the role of occupation in the incidence/localization of t...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/00015550260132488

    authors: Kumar B,Saraswat A,Kaur I

    更新日期:2002-01-01 00:00:00

  • Epidermal and urethroid penile cyst.

    abstract::The authors describe a 74-year-old man who presented with a 2-cm nodule on the ventral face of the penis, showing histologically a cyst lined by both epidermal and urethroid epithelium. The authors discuss the various histological forms of raphe median cysts of the penis. ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Claudy AL,Dutoit M,Boucheron S

    更新日期:1991-01-01 00:00:00

  • 5-S-Cysteinyldopa and dopa in serum during treatment with 8-methoxypsoralen and UVA light.

    abstract::5-S-Cysteinyldopa and dopa concentrations in serum were studied by high-performance liquid chromatography (HPLC) in patients with psoriasis treated by 8-methoxypsoralen and UVA light. A marked increase in 5-S-Cysteinyldopa was found after 3 days' treatment, although no increase in pigmentation could yet be observed. T...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Hansson C,Rorsman H,Rosengren E,Tegner E

    更新日期:1981-01-01 00:00:00

  • Lymphocyte transformation induced by nickel sulphate: an in vitro study of subjects with and without a positive nickel patch test.

    abstract::Lymphocytes from 8 patients with contact dermatitis and a positive nickel patch test, 7 patients with contact dermatitis due to other factors and with a negative nickel patch test, and 9 other subjects, 7 of whom suffered from other dermatological disorders, were tested with the lymphocyte transformation test (LTT), u...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Svejgaard E,Morling N,Svejgaard A,Veien NK

    更新日期:1978-01-01 00:00:00

  • T-cell receptor excision circles (TREC) in CD4+ and CD8+ T-cell subpopulations in atopic dermatitis and psoriasis show major differences in the emission of recent thymic emigrants.

    abstract::We used T-cell receptor excision circles (TREC) to evaluate thymic function in adult patients with atopic dermatitis and psoriasis. We observed that men, but not women, with atopic dermatitis had a significantly faster decline in TREC content with increasing age compared with healthy men. In contrast, both men and wom...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0550

    authors: Just HL,Deleuran M,Vestergaard C,Deleuran B,Thestrup-Pedersen K

    更新日期:2008-01-01 00:00:00

  • Scanning electromicroscopy of suction blister-roofs from psoriatic lesions and normal skin.

    abstract::Suction blisters were raised on psoriatic lesions and normal appearing skin. The epidermis was separated at the epidermal-dermal junction. Scanning electronmicroscopy of the dermal side of the blister-roofs from normal looking skin and almost healed psoriatic lesions showed stellate cells probably formed by cytoplasmi...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Juhlin L,Pautrat G,Ortonne JP

    更新日期:1985-01-01 00:00:00

  • Contact allergy to gold and gold therapy in patients with rheumatoid arthritis.

    abstract::Patients with rheumatoid arthritis were investigated for contact allergy to gold in connection with treatment with gold preparations. There were 57 patients with rheumatoid arthritis previously treated with gold, with or without cutaneous side-effects, as well as 20 patients intended for such treatment; all were expos...

    journal_title:Acta dermato-venereologica

    pub_type: 临床试验,杂志文章

    doi:10.2340/0001555577370373

    authors: Möller H,Svensson A,Björkner B,Bruze M,Lindroth Y,Manthorpe R,Theander J

    更新日期:1997-09-01 00:00:00

  • Hair root studies in patients suffering from primary and secondary syphilis.

    abstract::The hair root status (trichogram) was studied in eleven patients with primary and eight with secondary syphilis. Variables studied in addition to the hair roots were absence or presence of hair root sheaths, deformities and hair roots with angulations exceeding 20 degrees. A decrease in the number of anagen hair roots...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: van der Willigen AH,Peereboom-Wynia JD,van der Hoek JC,Mulder PG,van Joost TH,Stolz E

    更新日期:1987-01-01 00:00:00

  • Generalized normolipemic plane xanthomatosis associated with relapsing polychondritis.

    abstract::Generalized normolipemic plane xanthomatosis is a rare cutaneous disorder, frequently associated with reticuloendothelial diseases and some disorders with inflammation. Relapsing polychondritis is also a rare disease that shows an association with various immune-mediated diseases. We report a case of generalized normo...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/0001555574221223

    authors: Yoshimura T,Aiba S,Tadaki T,Tagami H

    更新日期:1994-05-01 00:00:00

  • Autochthonous Cutaneous Larva Migrans in France and Europe.

    abstract::Cutaneous larva migrans is a dermatitis, typically acquired in warm tropical or sub-tropical countries, caused by migration of the larvae of nematodes (hookworm; mainly Ancylostoma braziliense and, occasionally, Ancylostoma caninum or Uncinaria stenocephala), which are parasitic on animals such as cats and dogs, into ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章,评审

    doi:10.2340/00015555-3217

    authors: Del Giudice P,Hakimi S,Vandenbos F,Magana C,Hubiche T

    更新日期:2019-07-01 00:00:00

  • Shift in Occupational Risk for Basal Cell Carcinoma from Outdoor to Indoor Workers: A Large Population-based Case-control Register Study from Sweden.

    abstract::Basal cell carcinoma (BCC) is the most common form of cancer worldwide. Exposure of the skin to ultraviolet (UV) radiation, from sunlight and other sources, is the most important risk factor. The aim of this large-scale case-control study was to determine which occupations are associated with increased risk of BCC in ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-2660

    authors: Lindelöf B,Lapins J,Dal H

    更新日期:2017-07-06 00:00:00

  • Plasmin-like proteinase associated with high molecular weight complexes in blister fluid of bullous pemphigoid.

    abstract::Blister fluid from tense bullae of 10 patients with bullous pemphigoid was investigated using a radial caseinolysis assay and zymography. Proteolytic activity, varying from 4.7 to 10 micrograms/ml, was found in 3 out of 10 patients, by using the caseinolysis assay. Zymography revealed that a major part of this caseino...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Lauharanta J,Salonen EM,Vaheri A

    更新日期:1989-01-01 00:00:00

  • The effect of H1 and H2 receptor antagonists on the dermographic response.

    abstract::The effect on dermographic wealing of an H1 and H2 receptor antagonist was studied separately and in combination. a double-blind protocol was used and dermographism was measured as the diameter of weal response to a measured force. Both H1 and H2 antagonists had a small but non-significant effect, but the combination ...

    journal_title:Acta dermato-venereologica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Cook J,Shuster S

    更新日期:1983-01-01 00:00:00

  • Microorganisms in intertriginous psoriasis: no evidence of Candida.

    abstract::Infection can be a trigger and an aggravating factor in psoriasis. Antibacterial and/or antifungal agents are commonly used in the treatment of intertriginous psoriasis, because it is believed that flexures in psoriasis are often colonized by Candida species and Staphylococcus aureus. Bacterial and fungal cultures wer...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/00015550310007463

    authors: Flytström I,Bergbrant IM,Bråred J,Brandberg LL

    更新日期:2003-01-01 00:00:00

  • Urinary proline to hydroxyproline ratio varies with age.

    abstract::Urinary excretion of proline and hydroxyproline was studied in five groups of subjects, viz. controls, pituitary dwarfs, familial dwarfs, patients with fibrodysplasia ossificans progressive and patients with generalized scleroderma. The ratio Pro/Hyp in the urinary fraction precipitated with 5 parts of acetone (1 + 5 ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Blumenkrantz N,Howitz P,Asboe-Hansen G

    更新日期:1979-01-01 00:00:00

  • Elevated colchicine sensitivity of dermal lymphocytes in mycosis fungoides.

    abstract::Lymphocytes in chronic lymphocytic leukaemia and in other malignant lymphomas exhibit an extreme sensitivity to colchicine and are cytolysed in vitro by 10(-6) M colchicine. This characteristic can be quantified with the colchicine sensitivity index which is used for diagnostic purposes. We have demonstrated that lymp...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Sterry W,Steigleder GK,Nikolai B

    更新日期:1980-01-01 00:00:00

  • Itch in Psoriasis: A New Look at Well-known Subject.

    abstract::Psoriasis is a chronic inflammatory dermatosis, frequently presenting with chronic itch. This study investigated the prevalence and detailed clinical characteristics of chronic itch in 143 psoriatic patients, with regard to different age groups, comorbidities and pharmacotherapy. Chronic itch was reported by 72% of su...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-3147

    authors: Reszke R,Białynicki-Birula R,Szepietowski JC

    更新日期:2019-04-01 00:00:00

  • Coping strategies in melanoma patients.

    abstract::An observational, questionnaire-based, cross-sectional study was performed to assess whether differences in coping behaviour (positive and negative strategies) between patients with either a recent diagnosis of malignant melanoma (MM) or with benign dermatological disease, were predictive of the diagnosis. Coping stra...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-1351

    authors: Trapp M,Trapp EM,Richtig E,Egger JW,Zampetti A,Sampogna F,Rohrer PM,Komericki P,Strimitzer T,Linder MD

    更新日期:2012-11-01 00:00:00

  • Response of the clinically uninvolved skin of psoriatic patients to tape stripping during acitretin treatment.

    abstract::The aromatic retinoids etretinate and acitretin are widely used in the systemic treatment of severe psoriasis. The purpose of the present investigation was to further elucidate the mode of action of acitretin on abnormal keratinization and epidermal hyperproliferation in an in vivo model. Studies on the interference o...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/000155557669

    authors: Gerritsen MJ,van Pelt JP,van de Kerkhof PC

    更新日期:1996-01-01 00:00:00

  • Radiological changes of the hands in systemic sclerosis.

    abstract::Radiological examination of the hands was performed in 41 patients with systemic sclerosis. Pathological changes were found in 39 patients. Eighteen patients had subcutaneous calcifications and 11 had atrophy of the finger pulps. Bone resorption of ungual tufts was found in 11 patients. Juxta-articular osteoporosis wa...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Brun B,Serup J,Hagdrup H

    更新日期:1983-01-01 00:00:00

  • Therapeutic effectiveness of various treatments for eosinophilic pustular folliculitis.

    abstract::Eosinophilic pustular folliculitis is a rare dermatosis. Recently, in addition to oral indomethacin, other treatments have been applied for eosinophilic pustular folliculitis. The aim of this study was to assess the effectiveness of various therapies encompassing conventional to newly applied drugs for eosinophilic pu...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0578

    authors: Fukamachi S,Kabashima K,Sugita K,Kobayashi M,Tokura Y

    更新日期:2009-01-01 00:00:00

  • Bullous pyoderma gangrenosum in association with myeloid leukaemia.

    abstract::The case is presented of a patient with busulfan (Myleran) treated myeloid leukaemia, who developed bullous pyoderma gangrenosum. Skin symptoms appeared at the time when treatment was discontinued due to signs of bone marrow depression. The pyoderma disappeared following treatment with systemic steroid. ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Cramers M

    更新日期:1976-01-01 00:00:00

  • A comparison of treatment of oral lichen planus with topical tacrolimus and triamcinolone acetonide ointment.

    abstract::Treatment of symptomatic oral lichen planus remains a challenging problem. This study compared the efficacy of topical tacrolimus ointment with triamcinolone acetonide ointment in patients with oral lichen planus. Twenty patients (group I) were treated with topical tacrolimus 0.1% ointment 4 times daily, and 20 (group...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章,随机对照试验

    doi:10.2340/00015555-0070

    authors: Laeijendecker R,Tank B,Dekker SK,Neumann HA

    更新日期:2006-01-01 00:00:00

  • The hairless mouse as a model for study of local and systemic atrophogenic effects following topical application of corticosteroids.

    abstract::The hairless mouse has been used as a model to distinguish between local and systemic atrophogenic effects of topical steroids. Hydrocortisone-17-butyrate, betamethasone-17-valerate, budesonide and clobetasol-17-propionate were applied topically daily for 21 days. Skinfold thickness and dermal DNA synthesis of treated...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: van den Hoven WE,van den Berg TP,Korstanje C

    更新日期:1991-01-01 00:00:00

  • Genomic fingerprinting in the epidemiology of gonorrhoea.

    abstract::We investigated the usefulness of the restriction enzyme (RE) fingerprinting for epidemiological tracing in gonococcal disease. The RE patterns of three paired gonococcal isolates showed corresponding identical fingerprints. Within each of the three pairs of epidemiologically linked isolates the respective restriction...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Falk ES,Danielsson D,Bjorvatn B,Melby K,Sørensen B,Kristiansen BE

    更新日期:1985-01-01 00:00:00

  • Metastasizing erythroplasia Queyrat. Report of a case.

    abstract::A typical clinical and histologic case of Queyrat's erythroplasia of the glans penis is presented. For several years the patient had been treated for balanitis and inflammation of the glans. A few months before the patient died, the correct diagnosis was established. Shortly after, metastases to the inguinal lymph nod...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Avrach WW,Christensen HE

    更新日期:1976-01-01 00:00:00

  • Expression of loricrin in skin disorders.

    abstract::Loricrin, the major component of the cornified envelope, is normally expressed in the granular layer of epidermis during the last steps of keratinocyte differentiation. Using an antiloricrin antiserum (A8-73), an increased expression of this envelope precursor was found in some disorders of hyperorthokeratosis (ichthy...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:102340/0001555572407409

    authors: Juhlin L,Magnoldo T,Darmon M

    更新日期:1992-11-01 00:00:00

  • Herpes simplex infection simulating a positive auto-inoculation for Haemophilus ducreyi.

    abstract::Auto-inoculation from a genital ulcer suspected of being ulcus molle gave redness after 24 hours and after 48 hours vesicles and pustules appeared. Cultivation from the auto-inoculation after the 48 hours was positive for herpes simplex virus type 2. Our observation underlines two points: auto-inoculation for the diag...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Jørgensen J,Menné T

    更新日期:1982-01-01 00:00:00

  • Measurement of the horny layer turnover after staining with dansyl chloride: description of a new method.

    abstract::A simple non-radioactive technique is described. The corneal layers were stained with 5% dansyl chloride ointment during 24-48 h of occlusion. The number of newly formed corneal layers were counted on sections from punch biopsies obtained at various intervals after the staining. The rate of formation is given as layer...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Johannesson A,Hammar H

    更新日期:1978-01-01 00:00:00

  • Structural analogues inhibit the sensitizing capacity of carvone.

    abstract::The aim of the study was to investigate the effect of non-allergenic structural analogues on the sensitizing potential of carvone, a fragrance allergen. The possibility that one molecule might inhibit the allergenic activity of another molecule has been debated for 25 years. The Research Institute for Fragrance Materi...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/000155501317208318

    authors: Karlberg AT,Nilsson AM,Luthman K,Nilsson JL

    更新日期:2001-11-01 00:00:00