Abstract：
:Two female patients suffering from progressive systemic sclerosis (PSS) of generalized type were treated with estriol for 10 months. Although complete cure was not achieved, considerable beneficial effects were observed in these patients, but no serious side effects. Thus, skin softening was observed on all involved parts of these patients, which was accompanied by increased mobility of large or medium-sized joints and improved pigmentation and cyanotic redness on fingers and extremities. However, no apparent improvement of internal organ involvement could be detected. Histopathologically, a drastic reduction of homogenization of collagen bundles in the dermis of affected forearms was seen in these patients following estriol treatment. To our knowledge this is the first report of estriol therapy for PSS.
journal_name
Acta Derm Venereoljournal_title
Acta dermato-venereologicaauthors
Katayama H,Ohsawa K,Yaoita Hsubject
Has Abstractpub_date
1984-01-01 00:00:00pages
168-71issue
2eissn
0001-5555issn
1651-2057journal_volume
64pub_type
杂志文章abstract：:MoAb AHS-7 labels the basement membrane of the skin. In this report, we have determined the precise localization and molecular nature of the antigen(s). After epidermal-dermal separation by suction blistering, the antigen(s) were detected on the epidermal side. Immunoelectron microscopy revealed the reaction product o...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:5-S-Cysteinyldopa (5-S-CD), a pheomelanin precursor, has been used as a biochemical marker of melanoma metastasis. Recently, 5-hydroxy-6-methoxyindole-2-carboxylic acid (5H6MI2C), a eumelanin-related metabolite, was shown to reflect well the degree of skin pigmentation. We measured the urinary excretion of 5H6MI2C and...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:A leukoplakic lesion of the prepuce is described with the histologic and ultrastructural features of epidermolytic hyperkeratosis. The lesion represents most likely a variant of epidermolytic leukoplakia recently observed in the vermilion border of the lip. ...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:Although pemphigus has recently been linked to psoriasis, the risk of emergence of pemphigus during the course of psoriasis is yet to be delineated. The aim of this study was to evaluate the risk of developing pemphigus during the course of psoriasis. A large-scale population-based longitudinal retrospective cohort st...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-3607
更新日期：2020-10-20 00:00:00
abstract：:Stratum corneum chymotryptic enzyme (SCCE) may be involved in desquamation, a process necessary for maintaining a normal anatomy at all sites where there is continuous turnover of cornified epithelia. Using immunohistochemistry and in situ hybridization, we have, in this work, analysed SCCE expression in the sebaceous...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/000155598443015
更新日期：1998-09-01 00:00:00
abstract：:Thirteen patients with port wine stains (PWS) were treated with argon laser therapy. Before and at different points in time following treatment, skin blood perfusion and temperature were mapped with laser Doppler imaging and thermography. In nine patients no elevation in blood perfusion was observed in the PWS in comp...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：102340/0001555572610
更新日期：1992-01-01 00:00:00
abstract：:Vitiligo is an acquired depigmenting disorder. To date, there is no predictive model for its response rate to narrowband ultraviolet B (NBUVB) phototherapy. The aim of this study was to investigate the different types of response of patients with non-segmental vitiligo undergoing NBUVB 3 times a week. Many patients wh...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-2889
更新日期：2018-04-16 00:00:00
abstract：:Studies on hydroxyproline and hydroxylysine, the two amino acids characteristic of collagen and related glycoproteins, were undertaken on biopsies of pathologic and clinically normal human skin. No statistically significant differences between clinically normal skin of mamma, thorax, axilla, femur, hip and sacral area...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of end-stage liver disease. The aim of this controlled cross-sectional study was to assess the association between NAFLD and hidradenitis suppurativa. NAFLD was assessed using hepatic ultrasound. A total of 125 patients with hidradenitis supp...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-3597
更新日期：2020-08-18 00:00:00
abstract：:The hairless mouse model of a UVA-induced dermal neutrophilic infiltrate was used to compare the efficacy of equal concentrations of name brand versus generic corticosteroids. The generic brand was significantly less effective in suppressing the inflammatory response. ...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555741819
更新日期：1994-01-01 00:00:00
abstract：:Different scoring systems have been developed to determine the severity of atopic dermatitis. The SCORAD (SCORing Atopic Dermatitis), one of the best validated systems, is suited for clinical trials, but is too complicated and time consuming for routine clinical use. The TIS score (Three Item Severity score), a simpli...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/000155599750010256
更新日期：1999-09-01 00:00:00
abstract：:Herpes simplex virus (HSV) infection is a possible pathogenic factor in Behçet's disease (BD). Using proteomics analysis, this study detected a target HSV protein. Serum IgA and IgG reactivities against the identified protein were evaluated in patients with BD and in BD-like mice. A total of 4 protein bands generated ...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-2127
更新日期：2015-11-01 00:00:00
abstract：:Eight out of 30 consecutive patients with AIDS and cryptococcal meningoencephalitis (26,7%) presented cutaneous involvement, in the form of papulo-nodular lesions in 3 patients, molluscum contagiosum-like lesions in 3 patients, and pustular-ulcerative lesions in 2 patients. Skin localization represented an untoward pr...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555767274
更新日期：1996-01-01 00:00:00
abstract：:Itch is known to be associated with psychological factors in adults, but has not been explored among adolescents. A cross-sectional, questionnaire-based population study involving adolescents born mostly in 1986 was carried out in 2004. A total of 4744 individuals were invited and the participation rate was 80%. The H...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-0554
更新日期：2009-01-01 00:00:00
abstract：:Lymphocytotoxic autoantibody (LCTA) was studied in 9 patients with active pemphigus and 19 patients with active systemic lupus erythematosus (SLE). All patients with SLE showed high titres of LCTA but only one patient with pemphigus had LCTA. In this paper we discuss the immunological significance of LCTA and the diff...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:Psoriasin, which is highly expressed in psoriasis, is encoded by a gene located within the epidermal differentiation complex. The aim of this study was to investigate the effect of endogenous psoriasin on disturbed keratinocyte differentiation in psoriasis. Immunohistochemical staining revealed a gradient of psoriasin...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-2596
更新日期：2017-04-06 00:00:00
abstract：:Forty-three nickel-allergic patients (40 females and 3 males) participated in this study which was designed to elucidate the correlation between quantitative in vivo and in vitro responses. All were patch-tested with various concentrations of nickel-sulphate serial-diluted in water. The lowest concentration eliciting ...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:The antimalarial drug chloroquine is also used in the prevention of photodermatoses and in patients with inflammatory connective diseases. The drug binds strongly to melanin. Melanocytic activity can be studied by analysis of the urinary markers of eumelanin (6-hydroxy-5-methoxyindole-2-carboxylic acid, 6H5MI-2-C) and...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/0001555575287289
更新日期：1995-07-01 00:00:00
abstract：:Atopic dermatitis is a multifactorial disorder probably caused by environmental factors in combination with susceptibility genes. The clinical similarity between atopic dermatitis and the eczema manifestation in patients with Wiskott-Aldrich syndrome made the previously identified WAS gene in chromosome sub-band Xpl 1...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/000155501317140043
更新日期：2001-10-01 00:00:00
abstract：:Air-borne contact dermatitis caused by Parthenium hysterophorus is a serious problem in India. Patients with this condition have to use corticosteroids regularly in order to maintain clinical remissions, but prolonged usage causes serious side-effects. The weed cannot be eradicated. We have used 3 therapeutic regimens...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章
doi：10.1080/000155500750012487
更新日期：2000-01-01 00:00:00
abstract：:Adequate sun protection is often neglected during occupational outdoor work. To investigate the acceptance and usability of sunscreens during outdoor work a single-blind, randomized-controlled, cross-over trial was performed in 40 subjects. Two sunscreen formulations were used daily on working days for 4 weeks at a ti...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章,随机对照试验
doi：10.2340/00015555-1667
更新日期：2014-03-01 00:00:00
abstract：:Infection can be a trigger and an aggravating factor in psoriasis. Antibacterial and/or antifungal agents are commonly used in the treatment of intertriginous psoriasis, because it is believed that flexures in psoriasis are often colonized by Candida species and Staphylococcus aureus. Bacterial and fungal cultures wer...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/00015550310007463
更新日期：2003-01-01 00:00:00
abstract：:Patients with atopic dermatitis were found to have an about 7-fold increased spontaneous proliferative response of peripheral blood lymphocytes and an about 4-fold elevation of CD3-dependent lymphocyte transformation as compared to normal controls. The CD3-dependent lymphocyte response in patients with severe atopic d...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/0001555575353356
更新日期：1995-09-01 00:00:00
abstract：:Vulvar vestibulitis is a major cause of entry dyspareunia in young women. The aim of this study was to evaluate a self-reported history of bacterial vaginosis, candidiasis, use of oral contraception and nulli-pregnancy as risk factors for vestibulitis. A retrospective examination of medical records was performed for 4...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-0250
更新日期：2007-01-01 00:00:00
abstract：:A patient with the Klippel Trenaunay Weber syndrome presented with prolonged bleeding from the finger tips during strenuous exercise. Tissue fibrinolysis studies showed increased fibrinolytic activity suggesting that the blood vessels in the affected limb may be functionally as well as anatomically abnormal. ...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:Itch is the most common dermatological symptom and worsens with stress. The general belief of a person in their own ability to cope in stressful situations, known as self-efficacy, is relevant in the management of chronic diseases other than skin diseases. The aim of this study was to explore the association between p...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-1309
更新日期：2012-09-01 00:00:00
abstract：:Atopic dermatitis is a chronic, relapsing inflammatory skin disorder characterized by local infiltration of T cells. To date, numerous reports have shown that Staphylococcus aureus may exacerbate atopic dermatitis, and superantigens produced by this organism are thought to be one of the major causative factors in atop...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/000155598442700
更新日期：1998-11-01 00:00:00
abstract：:Although atopic dermatitis is a skin disorder, it includes immune deviations such as T-cell accumulation and activation in the skin, resulting in chronic, relapsing eczema. The T-lymphocyte activation in the skin is not accompanied by specific allergies in up to two thirds of the patients. It has been shown that T-cel...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/0001555577020021
更新日期：1997-01-01 00:00:00
abstract：:The functions of polymorphonuclear leukocytes (PMNs) emigrating into the skin and of others separated simultaneously from the circulation were determined and compared in healthy individuals. The PMNs emigrating into the skin were separated with a skin chamber technique. The C3 rosette forming capacities of the skin mi...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Necrobiosis lipoidica diabeticorum is a chronic cutaneous complication of diabetes mellitus with microangiopathy as an important pathophysiologic factor. Because of the known success of hyperbaric oxygen in the treatment of chronic non-healing wounds, we used this mode of therapy to treat a diabetic patient with ulcer...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章
doi：10.2340/0001555573447448
更新日期：1993-12-01 00:00:00
