Doppler flow velocimetry of the splenic artery in the human fetus: is it a marker of chronic hypoxia?

Abstract:

OBJECTIVE:The aim of this investigation was to describe splenic artery flow velocity waveforms in the appropriate- and small-for-gestational-age human fetus. STUDY DESIGN:Splenic artery flow velocity waveforms were prospectively obtained from 95 appropriate- and 15 small-for-gestational-age fetuses with pulsed Doppler ultrasonography. The resistance index was used to quantify the Doppler waveform. RESULTS:A second-degree polynomial model expressed the changes of the resistance index in appropriate-for-gestational-age fetuses with advancing gestation (y = 0.057x [Weeks] - 0.001x2, r = 0.53, p < 0.001). In 14 of 15 (93%) small-for-gestational-age fetuses the splenic artery resistance index was below the mean for gestational age. In five of 15 (33%) small-for-gestational-age fetuses the resistance index of the splenic artery was < 2 SEMs. A trend toward a higher hematocrit was noted in the five fetuses with splenic artery resistance index values < 2 SEMs (50.2%) compared with other small-for-gestational-age fetuses (43.0%). CONCLUSION:Our results suggest that some small-for-gestational-age fetuses have decreased resistance at the level of the splenic artery. We postulate that the increased erythropoietin level, stimulated by hypoxia, results in decreased resistance at the level of the splenic artery in small-for-gestational-age fetuses. Finally, management of the small-for-gestational-age fetus may be aided by the study of the splenic artery waveforms.

journal_name

Am J Obstet Gynecol

authors

Abuhamad AZ,Mari G,Bogdan D,Evans AT 3rd

doi

10.1016/0002-9378(95)90005-5

subject

Has Abstract

pub_date

1995-03-01 00:00:00

pages

820-5

issue

3

eissn

0002-9378

issn

1097-6868

pii

0002-9378(95)90005-5

journal_volume

172

pub_type

杂志文章
  • Fetal movements in multiple pregnancy.

    abstract::Fetal activity in multiple pregnancies, as expressed by maternal daily fetal movement recordings, was compared with that in singleton pregnancies. It was found that the mean fetal activity in 33 cases of twins, six cases of triplets, one case of quadruplets, and one case of quintuplets was generally higher than that o...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(83)91079-7

    authors: Samueloff A,Evron S,Sadovsky E

    更新日期:1983-08-01 00:00:00

  • Pregnancy-related mortality in New York City, 1980 to 1984: causes of death and associated risk factors.

    abstract::To identify causes and risk factors for pregnancy-related mortality in New York City, we analyzed 224 pregnancy-related deaths that occurred from 1980 to 1984. The leading causes of death were ectopic pregnancy complications, embolism, intrapartum cardiac arrest, and hypertension. Mortality ratios were determined by c...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(11)80031-1

    authors: Syverson CJ,Chavkin W,Atrash HK,Rochat RW,Sharp ES,King GE

    更新日期:1991-02-01 00:00:00

  • Maternal virilization in pregnancy due to an unclassified sex-cord stromal neoplasm.

    abstract::Virilization in pregnancy has been reported with various ovarian neoplasms. Presented is a case of maternal virilization resulting from an unclassified sex-cord stromal neoplasm. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(85)90627-1

    authors: Quagliarello J,Blaustein A

    更新日期:1985-07-01 00:00:00

  • Prenatal observation of umbilical cord abnormalities: a triple knot and torsion of the umbilical cord.

    abstract::Umbilical cord abnormalities can be observed with ultrasonography. Two cases are described where a triple knot and torsion of the umbilical cord are observed. These cases allow the elucidation of the mechanics of formation of a triknot and torsion abnormality. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(93)90139-a

    authors: Collins JC,Muller RJ,Collins CL

    更新日期:1993-07-01 00:00:00

  • The remote prognosis of eclamptic women. Sixth periodic report.

    abstract::All but three of the 270 women surviving eclampsia at the Margaret Hague Maternity Hospital in the period 1931 through 1951 were traced to 1973-74. Seventy-six have died and 13 were not re-examined. In white women having eclampsia in the first pregnancy carried to viability the remote mortality rate is not increased o...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(76)90168-x

    authors: Chesley LC,Annitto JE,Cosgrove RA

    更新日期:1976-03-01 00:00:00

  • Isoxsuprine-induced release of pulmonary surfactant in the rabbit fetus.

    abstract::Rabbit fetuses were injected intramuscularly with 0.5 mg. of isoxsuprine on the twenty-eighth day of gestation. They were killed in utero four hours after the injection, and fetal pulmonary fluid (FPF) was collected through a tracheal catheter. The quantity of FPF and the lung weight/body weight ratio were both signif...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(77)90744-x

    authors: Enhorning G,Chamberlain D,Contreras C,Burgoyne R,Robertson B

    更新日期:1977-09-15 00:00:00

  • Radiographic measures of the mid pelvis to predict cesarean delivery.

    abstract:OBJECTIVE:The purpose of this study was to determine whether x-ray measures of the mid pelvis can be used to predict cesarean delivery. STUDY DESIGN:Women were enrolled prospectively; x-ray pelvimetry was performed after delivery; the readers were blinded to the outcome. Groups were determined by mid pelvis measures (...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ajog.2013.02.050

    authors: Harper LM,Odibo AO,Stamilio DM,Macones GA

    更新日期:2013-06-01 00:00:00

  • Second-look operations in ovarian cancer.

    abstract::One hundred eighty-six patients with epithelial tumors of the ovary who were managed at the M. D. Anderson Hospital and Tumor Institute underwent an exploratory operation ("second-look" operation) to assess the status of the cancer. Fifty-eight patients were found to have no evidence of disease (NED) and chemotherapy ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(16)32778-8

    authors: Schwartz PE,Smith JP

    更新日期:1980-12-15 00:00:00

  • The evolving gender gap in general obstetrics and gynecology.

    abstract:OBJECTIVE:The purpose of this study was to analyze the trend in subspecialization among men graduating from obstetrics and gynecology residency programs. STUDY DESIGN:Results of the Survey of Residents Completing Training in New York State were analyzed for 1998 to 2003. The proportions of men and women graduating fro...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2006.07.043

    authors: Gerber SE,Lo Sasso AT

    更新日期:2006-11-01 00:00:00

  • Validity: what does it mean for competency-based assessment in obstetrics and gynecology?

    abstract::Validity refers to an evidence-based claim about the trustworthiness of decisions made from context-specific performance data. Validity requirements for competency-based assessments in obstetrics and gynecology have not been defined in the literature. We explain why validity is intrinsic to any discussion about compet...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2011.01.061

    authors: Andreatta PB,Marzano DA,Curran DS

    更新日期:2011-05-01 00:00:00

  • Postpartum intrauterine devices: clinical and programmatic review.

    abstract::The immediate postpartum period is a critical moment for contraceptive access and an opportunity to initiate long-acting reversible contraception, which includes the insertion of an intrauterine device. The use of the intrauterine device in the postpartum period is a safe practice with few contraindications and many b...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ajog.2018.07.013

    authors: Goldthwaite LM,Cahill EP,Voedisch AJ,Blumenthal PD

    更新日期:2018-09-01 00:00:00

  • Natural history of chronic proteinuria complicating pregnancy.

    abstract:OBJECTIVE:Although the significance of proteinuria is well-documented for pregnancy complicated by preeclampsia or diabetes, protein excretion of up to 300 mg per day is considered normal for uncomplicated pregnancy. Our purpose was to determine the significance of otherwise "asymptomatic" proteinuria identified during...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(11)91692-5

    authors: Stettler RW,Cunningham FG

    更新日期:1992-11-01 00:00:00

  • Evaluation and management of complications from synthetic mesh after pelvic reconstructive surgery: a multicenter study.

    abstract:OBJECTIVE:The purpose of this study was to describe the evaluation and management of synthetic mesh-related complications after surgery for stress urinary incontinence (SUI) and/or pelvic organ prolapse (POP). STUDY DESIGN:We conducted a multicenter, retrospective analysis of women who attended 4 US tertiary referral ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ajog.2013.10.012

    authors: Abbott S,Unger CA,Evans JM,Jallad K,Mishra K,Karram MM,Iglesia CB,Rardin CR,Barber MD

    更新日期:2014-02-01 00:00:00

  • Cotton-tipped applicator test: validity and reliability in chronic pelvic pain.

    abstract:OBJECTIVE:We sought to assess the concurrent validity and interrater reliability of the cotton-tipped applicator (CTA) test as a screening tool for diagnosis of cutaneous allodynia in patients with viscerally related chronic pelvic pain (CPP). STUDY DESIGN:We performed a prospective cohort comparative observational st...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2012.11.005

    authors: Nasr-Esfahani M,Jarrell J

    更新日期:2013-01-01 00:00:00

  • Postsurgical medical treatment of advanced endometriosis: results of a randomized clinical trial.

    abstract:OBJECTIVE:Our purpose was to investigate the efficacy of postsurgical treatment with nafarelin in women with advanced endometriosis. STUDY DESIGN:Eligible for trial were women < or = 38 years old with unexplained infertility with or without chronic pelvic pain and stage III or IV endometriosis according to the America...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0002-9378(94)90133-3

    authors: Parazzini F,Fedele L,Busacca M,Falsetti L,Pellegrini S,Venturini PL,Stella M

    更新日期:1994-11-01 00:00:00

  • The effect of monocyte chemotactic protein 1 in intraperitoneal adhesion formation in a mouse model.

    abstract:OBJECTIVE:Intraperitoneal adhesions are a significant cause of morbidity among women of reproductive age. Monocyte chemotactic protein 1 plays a role in the chemotaxis of mononuclear cells and fibroblasts into the peritoneal injury site. To evaluate its role in intraperitoneal adhesion formation, we used an established...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(98)70376-x

    authors: Zeyneloglu HB,Seli E,Senturk LM,Gutierrez LS,Olive DL,Arici A

    更新日期:1998-08-01 00:00:00

  • Effect of hydatidiform molar vesicular fluid on blood coagulation.

    abstract::The effect of fluids from both complete and partial hydatidiform moles on blood coagulation was determined. Coagulation was evaluated with use of the one-stage prothrombin time and the activated partial thromboplastin time. These studies demonstrated that the fluids shortened the activated partial thromboplastin time ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(85)80263-5

    authors: Kaplan SS,Szulman AE,Surti U

    更新日期:1985-11-15 00:00:00

  • Perinatal risk indicators for long-term neurological morbidity among preterm neonates.

    abstract:OBJECTIVE:Many obstetric interventions are performed to improve long-term neonatal outcome. However, long-term neonatal outcome is usually not a primary outcome because it is time-consuming and expensive. The aim of this project was to identify different perinatal risk indicators and to develop prediction models for ne...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2011.02.055

    authors: Teune MJ,van Wassenaer AG,van Dommelen P,Mol BW,Opmeer BC,Dutch POPS-19 Collaborative Study Group.

    更新日期:2011-05-01 00:00:00

  • Are choroid plexus cysts an indication for second-trimester amniocentesis?

    abstract::Previous series that described fetuses with choroid plexus cysts have been too small to determine whether there is an association with trisomy 18 sufficiently high to warrant amniocentesis. To address this issue, we studied the incidence of choroid plexus cysts and other ultrasonographic abnormalities in 26 consecutiv...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(90)91304-u

    authors: Benacerraf BR,Harlow B,Frigoletto FD Jr

    更新日期:1990-04-01 00:00:00

  • The reporting of pre-existing maternal medical conditions and complications of pregnancy on birth certificates and in hospital discharge data.

    abstract:OBJECTIVE:The purpose of this study was to determine the accuracy of live-birth certificates and hospital discharge data that reported of pre-existing maternal medical conditions and complications of pregnancy. STUDY DESIGN:We conducted a population-based validation study in 19 non-federal short-stay hospitals in Wash...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2005.02.096

    authors: Lydon-Rochelle MT,Holt VL,Cárdenas V,Nelson JC,Easterling TR,Gardella C,Callaghan WM

    更新日期:2005-07-01 00:00:00

  • Outcomes of transvaginal uterosacral ligament suspension: systematic review and metaanalysis.

    abstract::This systematic review of uterosacral ligament suspension provides a metaanalysis of anatomic outcomes and a summary of subjective outcomes. A successful anatomic outcome was considered present when women had "optimal" or "satisfactory" (pelvic organ prolapse quantification system stage 0 or 1) outcomes. In the anteri...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ajog.2009.07.052

    authors: Margulies RU,Rogers MA,Morgan DM

    更新日期:2010-02-01 00:00:00

  • Measurement of fetal forelimb movements in the lamb in utero.

    abstract::Forelimb movements in the unanesthetized fetal lamb in utero were measured by means of transit-time ultrasound in conjunction with triceps and biceps electromyographic activity. The relationships between forelimb movements and electrocortical activity, hypoxia, and spontaneous labor were studied. There was no evidence...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(81)90231-3

    authors: Natale R,Clewlow F,Dawes GS

    更新日期:1981-07-01 00:00:00

  • Prolonged effects of a novel, low-dosage continuous progestin-cyclic estrogen replacement program in postmenopausal women.

    abstract:OBJECTIVE:Our objective was to ascertain long-term tolerability and effects of a novel, low-dosage continuous progestin-cyclic estrogen regimen on vasomotor flushing, vaginal bleeding patterns, bone density, and plasma lipoprotein lipids. STUDY DESIGN:Eighteen postmenopausal women with climacteric symptoms received lo...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(92)91842-x

    authors: Plunkett ER,Wolfe BM

    更新日期:1992-01-01 00:00:00

  • The effects of dexamethasone and betamethasone on surfactant protein-B messenger RNA expression in human type II pneumocytes and human lung adenocarcinoma cells.

    abstract:OBJECTIVE:The purpose of this study was to compare the effect of a single 48-hour exposure to betamethasone or dexamethasone in the NCI-H441 cell line and in human type II pneumocytes. STUDY DESIGN:NCI-H441 cells were exposed 48 hours to varying concentrations of betamethasone or dexamethasone (10(-10) to 10(-7) mol/L...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2004.01.015

    authors: Ramin SM,Vidaeff AC,Gilstrap LC 3rd,Bishop KD,Jenkins GN,Alcorn JL

    更新日期:2004-04-01 00:00:00

  • Glucocorticoids and the rhesus fetal lung.

    abstract::The effects of glucocorticoids on primate fetal lung function have not been clearly delineated. In this prospective study of preterm rhesus fetuses exposed in utero to betamethasone for 72 hours, the most significant alteration was a striking increase in maximum lung volumes. Functionally less significant increases in...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(78)90267-3

    authors: Johnson JW,Mitzner W,London WT,Palmer AE,Scott R,Kearney K

    更新日期:1978-04-15 00:00:00

  • Automated, ambulatory, or conventional blood pressure measurement in pregnancy: which is the better predictor of severe hypertension?

    abstract:OBJECTIVES:Our purpose was to investigate the benefit, if any, of automated blood pressure monitoring over obstetric day unit conventional blood pressure measurement in the assessment of hypertensive pregnancies. STUDY DESIGN:A prospective, observational study was carried out in two large teaching hospitals. Three hun...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(98)70432-6

    authors: Penny JA,Halligan AW,Shennan AH,Lambert PC,Jones DR,de Swiet M,Taylor DJ

    更新日期:1998-03-01 00:00:00

  • Dioxin-like activity and maternal thyroid hormone levels in second trimester maternal serum.

    abstract:OBJECTIVE:Developmental exposure to dioxin-like compounds has been associated with cognitive and motor impairments in children. These toxicants have been shown to be thyroid toxicants in animal studies. Therefore, the objective of this study was to quantify the overall dioxin-like activity in maternal serum and determi...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2005.08.013

    authors: Foster WG,Holloway AC,Hughes CL Jr

    更新日期:2005-12-01 00:00:00

  • Effects of progestins and relaxin on glycodelin gene expression in human endometrial cells.

    abstract:OBJECTIVE:Glycodelin is an endometrial protein proposed to play an important role in embryonic implantation. We examined the effects of progestins and relaxin on glycodelin transcription, synthesis, and secretion. STUDY DESIGN:Northern blotting, metabolic labeling, and fluorography were used to assess glycodelin messe...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(00)70333-4

    authors: Taylor RN,Vigne JL,Zhang P,Hoang P,Lebovic DI,Mueller MD

    更新日期:2000-04-01 00:00:00

  • External cephalic version beginning at 34 weeks' gestation versus 37 weeks' gestation: a randomized multicenter trial.

    abstract:OBJECTIVE:In about 3% to 4% of all pregnancies at term, the fetal presentation will be noncephalic. External cephalic version (ECV) at term has been shown to decrease the rate of noncephalic presentation at birth and to decrease the rate of cesarean section associated with breech presentation. However, success rates fo...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1067/mob.2003.442

    authors: Hutton EK,Kaufman K,Hodnett E,Amankwah K,Hewson SA,McKay D,Szalai JP,Hannah ME

    更新日期:2003-07-01 00:00:00

  • Effect of antenatal exposure to Saint John's wort (Hypericum) on neurobehavior of developing mice.

    abstract:OBJECTIVE:We conducted, in a randomized, placebo-controlled manner, behavioral testing on mice offspring exposed antenatally to the herbal antidepressant Saint John's wort (Hypericum ). STUDY DESIGN:A daily dose of Saint John's wort (0.75 mg/g of food consumed), equivalent to that in human beings according to body sur...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2000.108889

    authors: Rayburn WF,Christensen HD,Gonzalez CL

    更新日期:2000-11-01 00:00:00