Abstract:
INTRODUCTION:Urethral valves can be of enormous clinical importance. Both the prognosis for an affected fetus and the indication for a prenatal therapeutic intervention depend to a high degree on the accuracy of the prenatal diagnosis. PATIENTS AND METHODS:The sonographic findings and the results of the postnatal diagnostic workup of 24 boys treated for urethral valves in our institute are analyzed in the present paper. RESULTS:Out of a group of 900 children, diagnosed prenatally as having urinary tract anomalies, the postnatal diagnostic workup revealed 24 boys suffering from posterior urethral valves. The combination of megacystis, oligohydramnios, and bilateral renal abnormalities was present in 3 boys, and it was only in these cases that urethral valves were correctly identified as the underlying pathology. The largest group (n = 16) of these fetuses presented with bilateral hydronephrosis with and without megaureter. Megacystis in any combination with other findings was detected only in 4 patients. Oligohydramnios as a sign of impaired renal function was observed in four pregnancies. Four children suffered postnatally from beginning renal insufficiency. Eight infants (33%) required some form of respiratory support. This group included the 4 newborns with oligohydramnios during the pregnancy. CONCLUSIONS:Posterior urethral valves represent a rare but severe congenital malformation. They can disrupt the development of the entire urinary tract and may be life-limiting to the affected boy. Only rarely, however, are they manifested as the complete pathological picture on prenatal ultrasound. In most cases, bilateral impairment of the fetal renal development suggests severe subvesical obstruction. Thus in cases with bilateral renal impairment on prenatal ultrasonography, posterior urethral valves are to be excluded postnatally. Oligohydramnios is a predictor of a poor outcome of the renal function.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Eckoldt F,Heling KS,Woderich R,Wolke Sdoi
10.1159/000081586subject
Has Abstractpub_date
2004-01-01 00:00:00pages
296-301issue
4eissn
0042-1138issn
1423-0399pii
81586journal_volume
73pub_type
杂志文章abstract:OBJECTIVES:The aim of this study is to modify and validate a novel screening tool to determine the necessity of bone scans in Chinese PCa patients at the time of diagnosis. METHODS:Five-hundred-and-one patients diagnosed with PCa between 2010 and 2013 at Zhongshan Hospital, Fudan University, were included in the study...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000368912
更新日期:2015-01-01 00:00:00
abstract::From July 1992 to April 1994, 70 patients with prostatic cancer underwent laparoscopic pelvic lymph-node dissection (LPLD) before retropubic radical prostatectomy or afterloading therapy in our clinic. After an initial learning phase, the accuracy of LPLD was excellent, with only 3.0% residual nodes and no false-negat...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282756
更新日期:1995-01-01 00:00:00
abstract::149 men suffering from erectile failure underwent a standardized combined procedure including intracavernosal pharmacological injection test (P test) artificial erection, pharmacocavernosography and cavernosometry with analysis of intracavernosal erection pressure and pressure drop. Patients with negative P test were ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282163
更新日期:1991-01-01 00:00:00
abstract::Bisphosphonates are a standard treatment for metastatic bone disease, although agents vary in their potential for renal toxicity. This case report describes the reversal of zoledronic acid-induced renal toxicity by switching treatment to ibandronate in a patient with hormone-refractory prostate cancer and bone metasta...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000132707
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:Renal cell carcinoma (RCC) forming tumor thrombus (TT) of vena cava (VC) is characterized by poor prognosis. Nevertheless, the outcome of patients after radical surgery varies. To date only limited data concerning prognostic biomarkers in this RCC subgroup are available. METHODS:Out of 159 patients with pT3b/c...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000497279
更新日期:2019-01-01 00:00:00
abstract::We developed a new system to record urethral pressure curves separately for the anterior, posterior, right and left walls of the urethra. It consists of a catheter with four channels running radially along the axis in 90 degree sectors from the bladder to the external urethral orifice and expresses the data stereograp...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280976
更新日期:1984-01-01 00:00:00
abstract::The cross-antigenicity between streptococcus, Su strain (OK-432), and rat bladder cancer BC-47 was studied by the immunocytochemistry. Both anti-Su (OK-432) and anti-BC-47 reacted with both homo- and heterogenous antigens. The specificity of the PAP reactions using these sera was confirmed by absorption study of the f...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281504
更新日期:1989-01-01 00:00:00
abstract::The objective of the study was to evaluate possible changes of the gene expression and localization of the enzymes, heme oxygenase and nitric oxide synthase (NOS), with reference to increase of collagen type III in response to the partial obstruction of the bladder. Following initial obstruction, whole rat bladders we...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000099351
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:The regulation proteins retinoblastoma protein (pRb) and p16 play an important role in the cell cycle as tumor suppressors. pRb is the main substrate for the function of cyclin-dependent kinases during the cell cycle in the transition from G(1) to S phase. In this study, the immunohistochemical expression ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000320510
更新日期:2011-01-01 00:00:00
abstract::During a 2-year period, 37 patients with symptomatic metastatic prostatic cancer were included in a prospective randomized phase-III trial. Nineteen patients were randomized to subcapsular orchiectomy, and 18 to cyproterone acetate (CPA) treatment with a dose of 50 mg b.i.d. The median age of the patients was 74 years...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000282125
更新日期:1991-01-01 00:00:00
abstract:INTRODUCTION:The role of positron emission tomography (PET) with 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) is currently under evaluation in urologic oncology. The aim of the present study was to investigate the use of [18F]FDG positron emission tomography ([18F]FDG-PET) in the detection and treatment control of malign...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000048442
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVES:To give an overview of the literature concerning the clinical practice of Botulinum toxin A (BTA) treatment to meet the needs and knowledge of urologists. METHODS:A literature search was performed to BTA treatment, together with a survey among Dutch urologist. RESULTS:The registration trials used strict in...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000381881
更新日期:2015-01-01 00:00:00
abstract::119 patients with stage-IV renal cell carcinoma were treated using immunotherapy with autologous tumor vaccine. The immunization was carried out at monthly intervals, the patients were restaged every 3 months using X-ray, ultrasound scanning or computed tomography as well as bone scintigraphy in the follow-up. The pat...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1159/000281439
更新日期:1989-01-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to evaluate prognostic factors for patients with upper urinary tract urothelial carcinoma (UUT-UC) after nephroureterectomy and to seek a better way of finding more favorable clinical results for these patients. PATIENTS AND METHODS:We retrospectively reviewed the medical rec...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000335274
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:The urinary bladder is commonly involved in pelvic malignancy. The incidence of apparent extension into adjacent organs in locally advanced colorectal malignancy is 5-12%. It is not known with other pelvic malignancy. No guidelines are available for its management. Often a dilemma exists between cystectomy...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000092929
更新日期:2006-01-01 00:00:00
abstract::In an experimental canine model, topical application of phenylephrine hydrochloride (Neo-Synephrine) to the urethral mucosa was demonstrated to cause a rise of intraurethral pressure which persisted for over 2 h without any rise of arterial pressure. There was no intraurethral pressure change after the topical applica...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280047
更新日期:1976-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the management of urolithiasis in children since the development of extracorporeal shock-wave lithotripsy (ESWL). METHODS:Between 1988 and 1994, 37 children, aged from 2 to 15 years (mean 10), with upper tract urolithiasis were evaluated and treated. Lithogenic metabolic disorders or anomalies of...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282882
更新日期:1996-01-01 00:00:00
abstract::Proteus syndrome is a rare hamartomatous disorder comprising a broad spectrum of congenital malformations and overgrowth of multiple tissues. Some rare urogenital malformations have been reported before. This case is unique for the presence of multiple genitourinary anomalies including retroperitoneal cystic mass, int...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000089744
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:No relevant data have been published on the impact of retroperitoneal lymph node dissection (LND) on clinical outcome in patients with castration-resistant prostate cancer. METHODS:We retrospectively studied the records of 6 patients with lymph node metastases from castration-resistant prostate cancer who u...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000335206
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:To determine association between urine pH and OAB symptoms and to determine if urinary alkalization improves overactive bladder (OAB) symptoms. METHODS:659 patients with OAB were enrolled in this study between June 2012 and May 2014. 329 patients (group 1) were included in the final analysis. 201 adults wer...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000375322
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:To describe a case of cystic dysplasia of the testis (CDT), an uncommon cause of scrotal swelling in the pediatric patient. Clinic, therapy, fertility, and radiographic and pathologic findings are discussed and the 30 previously reported cases are reviewed. METHODS:A 9-year-old boy presented with asymptomat...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000064351
更新日期:2002-01-01 00:00:00
abstract::Negotiating a tortuous or obstructed ureter with a wire can be time-consuming and sometimes tiring. The principle of using a slippery floppy wire and then replacing it with a stiff wire through a 5-french open-ended ureteral catheter yields a high success rate. The ureteral catheter can be used for a radiocontrast stu...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282713
更新日期:1995-01-01 00:00:00
abstract:INTRODUCTION:Nearly 80% of the patients suffering from advanced stages of prostate cancer in Germany are treated currently with luteinizing hormone-releasing hormone (LH-RH) analogs alone or in combination with androgen receptor antagonists. The aim of this study was to assess whether the prescription practice for LH-R...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000096334
更新日期:2006-01-01 00:00:00
abstract::We report 2 patients with epididymo-orchitis, caused by Brucella melitensis, accompanied by severe delay of diagnosis. In 1 patient the correct diagnosis was only suspected after his wife had been diagnosed with brucellosis. Our cases illustrate that diagnosing brucellosis can be difficult in nonendemic areas, especia...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000218542
更新日期:2009-01-01 00:00:00
abstract::420 patients were treated with transurethral, intravesical electrotherapy to improve the function of paralyzed urinary bladder. Normal conscious micturition control was obtained by 314 patients. This electrotherapy contrasts sharply in method and goal with all implanted pacemakers or inserted electric plugs. Nor does ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000279979
更新日期:1975-01-01 00:00:00
abstract:INTRODUCTION:Obesity is usually considered a risk factor for postoperative complications; however, previous studies conclude contradictory results in retroperitoneal laparoscopic adrenalectomy (LA). We aim to evaluate the impact of obesity on the perioperative outcomes of LA. METHODS:A retrospective cohort study from ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000431183
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To conduct a meta-analysis examining p53 expression as a potential risk factor in upper urinary tract urothelial carcinoma (UUT-UC) and to systematically review the available data. METHODS:A comprehensive literature review was performed from January 1991 to August 2012, using search engines such as PubMed, E...
journal_title:Urologia internationalis
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000360227
更新日期:2015-01-01 00:00:00
abstract::We present an unusual case of condylomata acuminata arising in the transplanted skin of a neovagina in a male-to-female transsexual. The neovagina had been constructed using a penile and a scrotal skin flap. Resection of the larger condylomata was performed; then all visible lesions were ablated by electrovaporization...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000078811
更新日期:2004-01-01 00:00:00
abstract::The sequential expressed prostatic secretion (EPS) levels of latamoxef (LMOX) were measured in 14 patients with acute bacterial prostatitis to evaluate the diffusion of this antibiotic from the plasma into the prostatic fluid. All patients received 2 g of LMOX on the 1st, 4th, and 7th days of hospitalization. The mean...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282760
更新日期:1995-01-01 00:00:00
abstract::Alpha-fetoprotein (AFP) is recognized as a tumor marker of yolk sac tumors, liver cancer and some other cancers of the digestive organs. Renal cell carcinoma (RCC) producing AFP is a rare entity. A case of AFP-producing RCC with solitary bone metastasis, but without liver involvement, is reported. The stain specific t...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000050982
更新日期:2001-01-01 00:00:00