Abstract:
:The cross-antigenicity between streptococcus, Su strain (OK-432), and rat bladder cancer BC-47 was studied by the immunocytochemistry. Both anti-Su (OK-432) and anti-BC-47 reacted with both homo- and heterogenous antigens. The specificity of the PAP reactions using these sera was confirmed by absorption study of the first antibodies. But, OK-432 did not share with normal rat tissues. Furthermore, the presence of common antigens between OK-432 and animal tumors where OK-432 was effective was indicated by the PAP studies, but OK-432 did not share with tumors where OK-432 was ineffective. By the PAP studies using antigroup A streptococcus-specific C-polysaccharide and antigroup-specific sera, it was suggested that the determinant of the cross-antigenicity was group A-specific C-polysaccharide. The common antigens between OK-432 and human urogenital cancers were also identified by the PAP study. Then, local immunotherapy with OK-432 was carried out in 38 patients with superficial bladder tumor and the tumors were eliminated in 23.7%. In 77.8% of the complete response and in 10.3% of the no change, the tumor tissues demonstrated antigens common between OK-432 and tissues. From these results, it was concluded that common antigens which OK-432 shared with tumors could favorably augment host defense against human bladder tumors, the same as animal tumors.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Fujioka T,Aoki H,Yoshida M,Ohhori T,Kubo Tdoi
10.1159/000281504subject
Has Abstractpub_date
1989-01-01 00:00:00pages
198-204issue
4eissn
0042-1138issn
1423-0399journal_volume
44pub_type
杂志文章abstract:OBJECTIVE:Laparoscopic nephroureterectomy (LNU) offers a superior morbidity profile compared with open nephroureterectomy (ONU) in treating upper urinary tract urothelial cell carcinoma. Evidence of oncological equivalence between LNU and ONU is limited. We compare operative and oncological outcomes for LNU and ONU usi...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000364833
更新日期:2015-01-01 00:00:00
abstract:EPIDEMIOLOGY:The annual incidence of urolithiasis in the population is at least 0.1%. In rural areas, there are remarkably less actual stone formers than in urban districts, and also vegetarians show less stone diseases. Calcium carbonate as a urinary calculus compound is not in the strict sense impossible, but often a...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280781
更新日期:1981-01-01 00:00:00
abstract::During 1986 and 1987, 47 patients with renal cell carcinoma were evaluated preoperatively with CT, angiography and MRI. The preoperative tumor stage (T), lymph node metastases and venous involvement determined with the three methods were compared to the operative and histopathological findings. For T stage, angiograph...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282219
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:The initial objective of this renal cancer study was to identify gene sets in clear cell renal cell carcinoma (ccRCC) to support grading of ccRCC histopathology. MATERIALS AND METHODS:Preselected ccRCC tumor tissues of grade 1 (G1, n = 14) and grade 3 (G3, n = 15) as well es 14 normal kidney tissues thereof ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000328196
更新日期:2011-01-01 00:00:00
abstract::The objective of this case report is to present a rare bladder tumour in a young patient 25 years after the treatment with cyclophosphamide because of a neuroblastoma of the right eye. The first symptom of the tumour was macroscopic haematuria with dysuria and pollakiuria. The final diagnosis was dictaminated by the p...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000437442
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The best technique of radical prostatectomy--open retropubic versus robot-assisted surgery--is a subject of controversy. PATIENTS AND METHODS:Between January 1st, 2007 and December 31st, 2011, 2,177 men underwent radical prostatectomy at our department. 252 (12%) cases were laparoscopic robot-assisted, the ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000345320
更新日期:2013-01-01 00:00:00
abstract::Tumour markers which occur in blood or urine are of value in the management of cancer patients because they allow disease status to be monitored by non-invasive techniques at low cost. An antigen, 'B5', on erythrocytes has been shown to become enhanced when cancer develops, regardless of tumour type, and thus the B5 a...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281951
更新日期:1987-01-01 00:00:00
abstract::The present study was undertaken to analyze the changes in neuroendocrine cells of the human prostate induced by neoplasms and the effect of hormonal treatment. Samples of human prostate (n = 47) were obtained during surgery or removal of organs for transplantation. The cases analyzed represent normal prostates (n = 4...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000283051
更新日期:1997-01-01 00:00:00
abstract::Paragangliomas or extra-adrenal pheochromocytomas account for approximately 15% of all pheochromocytomas. They are usually found in an intradiaphragmatic location. Paragangliomas of the urinary bladder are infrequent and represent 6% of the paragangliomas and 0.06% of all bladder tumors. We describe 2 cases of urinary...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000080841
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:The objective of this study is to present the experience of 3 institutions performing renal autotransplantation (RAT) and to discuss surgical techniques employed and the results in the light of the medical literature. MATERIALS AND METHODS:A total of 14 patients (11 male and 3 female) with a mean age of 47 ±...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000448482
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:We investigated the hypothesis that testicles and scrotal skin undergo morphologic changes that would serve the mechanism of erection and ejaculation. MATERIALS AND METHODS:Testicular and scrotal skin changes during erection and ejaculation were studied in 9 dogs. Testicular volume was measured by ultrasound, ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000107960
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:Mini percutaneous nephrolithotomy (mini-PCNL) and retrograde intrarenal surgery (RIRS) are well-established techniques with little morbidity. The combined use of standard PCNL and the mini-PCNL or the RIRS technique was evaluated and compared to investigate their own role in the management of staghorn calc...
journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
doi:10.1159/000360708
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Sunitinib is standard first-line therapy for metastatic clear cell renal cancer (MCRC). It is associated with leucopenia; however, its effects on specific immune cell subsets are unclear. Alterations in immune cell subsets may contribute to tumour progression. METHODS:Lymphocyte subsets (CD3, 4, 8, 19 and 5...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章
doi:10.1159/000319498
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To assess perioperative complications and 90-day mortality of radical cystectomy (RC) in elderly patients with muscle-invasive bladder cancer (MIBC). MATERIALS AND METHODS:This is a retrospective, multicentre (n = 11) study of a consecutive series of patients ≥75 years who underwent RC for MIBC between 2006 ...
journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
doi:10.1159/000357127
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To report conservative and surgical strategies for treatment of mesh erosion after pelvic organ prolapse (POP) repair. METHODS:Between 1998 and 2008, 179 patients underwent integral pelvic floor reconstruction for advanced POP in our tertiary urogynecological unit. Patients' charts and follow-up data were en...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000324243
更新日期:2011-01-01 00:00:00
abstract::We report an unusual case of unilateral ureteral obstruction with secondary urinary extravasation by forniceal rupture as a complication of the Burch colposuspension procedure. Surprisingly, this complication has never been described before. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281485
更新日期:1989-01-01 00:00:00
abstract::This paper presents a case of gas-forming infection of the urinary tract in a diabetic patient. Plain film and computed tomography scans of the abdomen greatly facilitated clarification of the entire inflammatory process. The patient was cured by early nephrectomy conducted following unsuccessful treatment by percutan...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282602
更新日期:1994-01-01 00:00:00
abstract::We constructed a continent, catheterizable urinary conduit using a smooth muscle graft in dogs. One end of an isolated vascularized ileal segment was anastomosed to the bladder dome, and the other end was opened in the abdominal wall. The ileal conduit was tightly encircled with a free seromuscular flap of the ileum i...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282690
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVES:To review the incidence of healthcare-associated infections/urinary tract infection (UTI), risk factors, microorganisms isolated and antibiotic resistances in patients who underwent lower urinary tract endoscopic surgery (LUTES) in a tertiary care hospital. METHODS:A prospective observational study was carr...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000488251
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:This study was performed to look for an improvement of therapeutic strategies with regard to the treatment of infectious urinary stones using artificial stones made of struvite and apatite ('Bon(n) stones') which are comparable to their natural counterparts. MATERIALS AND METHODS:Using an experimental arran...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000063942
更新日期:2002-01-01 00:00:00
abstract:INTRODUCTION:To evaluate the feasibility and safety of bilateral single-session ureteroscopy in the treatment of bilateral stones with different localizations. MATERIALS AND METHODS:Between February 2001 and October 2006, a total of 1,296 patients underwent ureteroscopy with pneumatic lithotripsy. Of these, 38 patient...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000144061
更新日期:2008-01-01 00:00:00
abstract:INTRODUCTION:We have investigated the volume of nerve fibers in the rat urinary bladder following systematic exposure to cold-restraint stress and capsaicin treatment. MATERIALS AND METHODS:Adult Wistar albino rats were either exposed to cold-restraint stress (vehicle group) or treated with capsaicin before exposure t...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000074093
更新日期:2003-01-01 00:00:00
abstract::We report a rare case of massive bilateral staghorn calculi in a spinal cord injury patient with significant renal compromise. The patient was successfully treated with percutaneous nephrolithotomy to achieve a stone-free status. The various options of treatment are discussed with special attention to the technical as...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030340
更新日期:1998-01-01 00:00:00
abstract::A 63-year-old man with primary malignant lymphoma of the prostate is presented. The patient underwent total cystoprostatectomy and ileal conduit construction. The specimen revealed malignant lymphoma, diffuse small cleaved cell of the gland. Three months after the operation, local recurrence and enlarged lymph node de...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282216
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:This study aimed at comparing the urinary protein levels in calcium stone formers with those of healthy individuals. PATIENTS AND METHODS:From January 2002 until June 2004, 100 calcium stone formers (mean age 38.6 +/- 10.3 years), who had at least two episodes of calcium stone formation, were compared with 1...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000090882
更新日期:2006-01-01 00:00:00
abstract::Human infestation with Dioctophyma renale is presented. Clinical signs and diagnostic findings are unspecific. They are discussed and a conservative therapeutic approach is suggested. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000067695
更新日期:2003-01-01 00:00:00
abstract::We present a case of an appendicular mass mimicking symptoms of a bladder tumour in a 27-year-old female. The patient initially presented with a 5-month history of intermittent lower abdominal pain associated with dysuria, anorexia and weight loss. Cystoscopy revealed an erythematous urothelium with the appearance of ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000089178
更新日期:2005-01-01 00:00:00
abstract::Curative treatment of bladder cancer is limited to superficial tumors (Ta-T2). Advanced stages (T3a + T3b) can be treated only palliatively even when confined to the bladder (N0, M0). Nevertheless the differentiation between curable and incurable tumors is difficult. The classification of patients into the two differe...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281064
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:This study aims to examine the relationship between chronic prostatic inflammation and prostatic calculi, and clinical parameters of benign prostatic hyperplasia (BPH). MATERIALS AND METHODS:This study was based on 225 patients who underwent transurethral resection of the prostate for BPH. Chronic inflammati...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000342643
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Salvage high-intensity focused ultrasound (HIFU) and cryotherapy (CRYO) have emerged as interesting alternatives in the treatment of local radio-recurrent prostate cancer. Currently, recommendations concerning the use of CRYO and HIFU in the salvage setting are still evolving. AIM:The objective of this revi...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000339616
更新日期:2012-01-01 00:00:00