Abstract：
:Steroid derivatives V, VI, VII and VIII reacted with Lawesson's reagent (LR) to produce spiro-oxazaphosphole-4',17-androstene derivative XI, diazaphospholoandrostane XIV and the thionated derivatives XVI and XVII, respectively. The structures of the new compounds were confirmed by analytical and spectroscopic evidence. A mechanism accounting for the formation of the new compounds was given. The in vitro antimicrobial activity of the new compounds were tested.
journal_name
Steroidsjournal_title
Steroidsauthors
Mohamed NR,Elmegeed GA,Abd-ElMalek HA,Younis Mdoi
10.1016/j.steroids.2004.11.001subject
Has Abstractpub_date
2005-03-01 00:00:00pages
131-6issue
3eissn
0039-128Xissn
1878-5867pii
S0039-128X(05)00002-4journal_volume
70pub_type
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