Reduction of diffusion-weighted MRI lesion volume after early moderate hypothermia in ischemic stroke.

Abstract:

BACKGROUND:Large areas of restricted diffusion in the middle cerebral artery (MCA) territory are highly predictive of severe and potentially space-occupying MCA stroke. A reduction of diffusion-weighted MRI (DWI) lesions occurs in 20% to 40% of acute stroke patients with early reperfusion. METHODS:We report of a patient with a severe stroke syndrome who was treated with early moderate hypothermia but not thrombolysis. RESULTS:The initially large DWI deficit of the whole MCA territory contrasted to the relatively small final lesion restricted to the basal ganglia on MRI and computed tomography scan. CONCLUSIONS:This case describes an unexpected reduction of a DWI lesion after early moderate hypothermia and spontaneous recanalization 3 days after stroke onset. We discuss potential reasons for the unexpected DWI lesion reduction.

journal_name

Stroke

journal_title

Stroke

authors

Berger C,Schramm P,Schwab S

doi

10.1161/01.str.0000166057.96174.88

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

e56-8

issue

6

eissn

0039-2499

issn

1524-4628

pii

36/6/e56

journal_volume

36

pub_type

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