Salt, volume and the prevention of hypertension.

abstract：BACKGROUND:In people with atrial fibrillation (AF), periods of sinus rhythm present an opportunity to detect prothrombotic atrial remodeling through measurement of P-wave indices (PWIs)-prolonged P-wave duration, abnormal P-wave axis, advanced interatrial block, and abnormal P-wave terminal force in lead V1. We hypothe...

journal_title：Circulation

authors： Maheshwari A,Norby FL,Roetker NS,Soliman EZ,Koene RJ,Rooney MR,O'Neal WT,Shah AM,Claggett BL,Solomon SD,Alonso A,Gottesman RF,Heckbert SR,Chen LY

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:Current methods of signal-averaged ECG analysis interrogate the terminal 40 msec of the QRS complex and/or the ST segment and have a low positive-predictive accuracy for detecting vulnerability to sustained ventricular tachycardia (VT). The extent to which abnormalities detected during these ECG intervals ar...

journal_title：Circulation

authors： Hood MA,Pogwizd SM,Peirick J,Cain ME

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Current studies have demonstrated that applying therapeutic hypothermia for 12 to 24 hours after resuscitation from cardiac arrest improves the outcomes of cardiopulmonary resuscitation. The present study investigated whether a shorter duration of therapeutic hypothermia induced quickly and early after resus...

journal_title：Circulation

authors： Ye S,Weng Y,Sun S,Chen W,Wu X,Li Z,Weil MH,Tang W

更新日期：2012-01-03 00:00:00

abstract：BACKGROUND:Even in high-performing health systems, some patients with diabetes mellitus have poor blood pressure (BP) control because of poor medication adherence and lack of medication intensification. We examined whether the Adherence and Intensification of Medications intervention, a pharmacist-led intervention comb...

journal_title：Circulation

authors： Heisler M,Hofer TP,Schmittdiel JA,Selby JV,Klamerus ML,Bosworth HB,Bermann M,Kerr EA

更新日期：2012-06-12 00:00:00

abstract：BACKGROUND:The risk of syncope occurring while driving has obvious implications for personal and public safety. We aimed to define the clinical characteristics, causes, and prognosis of syncope while driving. METHODS AND RESULTS:In this case-control study of consecutive patients evaluated for syncope from 1996 through...

journal_title：Circulation

authors： Sorajja D,Nesbitt GC,Hodge DO,Low PA,Hammill SC,Gersh BJ,Shen WK

更新日期：2009-09-15 00:00:00

abstract：BACKGROUND:An inverse association between height and risk of coronary heart disease (CHD) has been reported in several case-control and cohort studies, but the reasons for the association remain uncertain. We evaluated this association among 22,071 male physicians, a population homogeneous for high educational attainme...

journal_title：Circulation

authors： Hebert PR,Rich-Edwards JW,Manson JE,Ridker PM,Cook NR,O'Connor GT,Buring JE,Hennekens CH

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Although long-term lipid-lowering therapy improves endothelium-dependent vasodilatation in humans, it remains unknown whether the short-term removal of LDL per se ameliorates endothelial dysfunction. METHODS AND RESULTS:To examine the effects of a single session of LDL apheresis on endothelial function in p...

journal_title：Circulation

authors： Tamai O,Matsuoka H,Itabe H,Wada Y,Kohno K,Imaizumi T

更新日期：1997-01-07 00:00:00

abstract：:The myocardial uptake of 125I- and 131I-antimyosin monoclonal antibody Fab in experimental myocarditis in BALB/c mice induced by encephalomyocarditis virus was studied. The biodistribution of 125I-antimyosin demonstrated that the highest ratio of radioactivity appears in the heart of infected mice on day 14 (the ratio...

journal_title：Circulation

authors： Matsumori A,Ohkusa T,Matoba Y,Okada I,Yamada T,Kawai C,Tamaki N,Watanabe Y,Yonekura Y,Endo K

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:The maintenance and termination of reentry arrhythmias are determined by tissue properties such as refractoriness and conduction velocity. Although the effects of Na(+) and K(+) channel block on electrophysiological properties and defibrillation threshold (DFT) have been studied, little is known about the ef...

journal_title：Circulation

authors： Qi X,Varma P,Newman D,Dorian P

更新日期：2001-09-25 00:00:00

abstract：:Malignant hyperthermia is a disease resulting from defective cellular membranes, usually presenting as drug-induced pyrexic crises. We describe four patients with life threatening ventricular arrhythmias or chest pain in the absence of pyrexic crises. Three presented with life threatening arrhythmias and the fourth wi...

journal_title：Circulation

authors： Huckell VF,Staniloff HM,Britt BA,Waxman MB,Morch JE

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:Percutaneous transluminal coronary angioplasty of the infarct-related artery in stable survivors of acute myocardial infarction is often performed, even in patients without any symptoms or residual ischemia. Despite the lack of randomized studies, it is widely believed that this intervention will improve the...

journal_title：Circulation

authors： Zeymer U,Uebis R,Vogt A,Glunz HG,Vöhringer HF,Harmjanz D,Neuhaus KL,ALKK-Study Group.

更新日期：2003-09-16 00:00:00

abstract：:Using nondenaturing polyacrylamide gel electrophoresis, we have identified two distinct myosin isoenzymes in human atrial tissue that correspond to the V1 and V3 isomyosins found in rat ventricular tissue. Normal left and right atrial appendages have approximately 50% V3. When the left atrium was exposed to hemodynami...

journal_title：Circulation

authors： Buttrick PM,Malhotra A,Brodman R,McDermott L,Lam L

更新日期：1986-09-01 00:00:00

abstract：:Finn Waagstein was born in Copenhagen in 1938. He graduated from Aarhus University Medical School in 1964. He received his cardiology training in the Sahlgrenska University Hospital at the University of Gothenburg, Sweden. He was appointed Associate Professor in 1980, and he assisted in establishing and directing the ...

journal_title：Circulation

authors： Waagstein F,Rutherford JD

更新日期：2017-09-05 00:00:00

abstract：BACKGROUND:Cardiac volume overload by an aortocaval shunt increases left ventricular end-diastolic pressure (LVEDP) and plasma and cardiac renin activity and results in LV hypertrophy. To a similar extent, the angiotensin-converting enzyme (ACE) inhibitors enalapril and quinapril prevent the increase in LVEDP. However,...

journal_title：Circulation

authors： Ruzicka M,Skarda V,Leenen FH

更新日期：1995-12-15 00:00:00

abstract：:Between 1972 and 1984, 100 consecutive neonates (less than or equal to 30 days old) underwent repair of coarctation of the aorta. Mean (+/- SD) age at operation was 12.0 +/- 8.0 days; mean weight was 3.1 +/- 0.5 kg. Simple coarctation was present in 29 patients (group I), 32 patients had additional ventricular septal ...

journal_title：Circulation

authors： Ziemer G,Jonas RA,Perry SB,Freed MD,Castaneda AR

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Vasomotor reactivity may contribute to the pathophysiology of ischemic injury. The atherosclerotic vessel may be particularly susceptible to vasoconstriction because of the damaged endothelial layer with resultant loss of vasodilatory factors. While dietary omega 3 fatty acids have been proposed to protect a...

journal_title：Circulation

authors： Malis CD,Leaf A,Varadarajan GS,Newell JB,Weber PC,Force T,Bonventre JV

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Various measures of arterial stiffness and wave reflection have been proposed as cardiovascular risk markers. Prior studies have not assessed relations of a comprehensive panel of stiffness measures to prognosis in the community. METHODS AND RESULTS:We used proportional hazards models to analyze first-onset...

journal_title：Circulation

authors： Mitchell GF,Hwang SJ,Vasan RS,Larson MG,Pencina MJ,Hamburg NM,Vita JA,Levy D,Benjamin EJ

更新日期：2010-02-02 00:00:00

abstract：BACKGROUND:Blood oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI) has been used to measure T2* changes in skeletal muscle tissue of healthy volunteers. The BOLD effect is assumed to primarily reflect changes in blood oxygenation at the tissue level. We compared the calf muscle BOLD response of patien...

journal_title：Circulation

authors： Ledermann HP,Schulte AC,Heidecker HG,Aschwanden M,Jäger KA,Scheffler K,Steinbrich W,Bilecen D

更新日期：2006-06-27 00:00:00

abstract：:Hemodynamic effects of dobutamine and dopamine (both 5, 10, 15 microgram/kg/min) and epinephrine (0.04 microgram/kg/min) were studied immediately following cessation of cardiopulmonary bypass in 34 patients with preoperative evidence of left ventricular dysfunction. Significant increases in mean cardiac index were see...

journal_title：Circulation

authors： Steen PA,Tinker JH,Pluth JR,Barnh;rst DA,Tarhan S

更新日期：1978-02-01 00:00:00

abstract：:Although for most children the process of atherosclerosis is subclinical, dramatically accelerated atherosclerosis occurs in some pediatric disease states, with clinical coronary events occurring in childhood and very early adult life. As with most scientific statements about children and the future risk for cardiovas...

journal_title：Circulation

authors： Kavey RE,Allada V,Daniels SR,Hayman LL,McCrindle BW,Newburger JW,Parekh RS,Steinberger J,American Heart Association Expert Panel on Population and Prevention Science.,American Heart Association Council on Cardiovascular Disease in the

更新日期：2006-12-12 00:00:00

abstract：BACKGROUND:The excess risk of atherosclerosis among patients with non-insulin dependent diabetes mellitus (NIDDM) is well documented. However, the presence of conventional risk factors cannot fully account for this excess risk, and the underlying mechanism remains to be elucidated. The present study prospectively evalu...

journal_title：Circulation

authors： Austin MA,Mykkänen L,Kuusisto J,Edwards KL,Nelson C,Haffner SM,Pyörälä K,Laakso M

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Ruling out acute myocardial infarction (AMI) on the basis of rapid assays for cardiac markers will allow early triage of patients and cost-effective use of available coronary care facilities. METHODS AND RESULTS:We studied the value of myoglobin, creatine kinase (CK)-MBmass, and troponin T in ruling out an ...

journal_title：Circulation

authors： de Winter RJ,Koster RW,Sturk A,Sanders GT

更新日期：1995-12-15 00:00:00

abstract：BACKGROUND:Recent transcatheter aortic valve replacement studies have raised concerns about adverse cerebrovascular events. The etiopathology of the embolized material is currently unknown. METHODS AND RESULTS:A total of 40 patients underwent transcatheter aortic valve replacement with the use of a dual filter-based e...

journal_title：Circulation

authors： Van Mieghem NM,Schipper ME,Ladich E,Faqiri E,van der Boon R,Randjgari A,Schultz C,Moelker A,van Geuns RJ,Otsuka F,Serruys PW,Virmani R,de Jaegere PP

更新日期：2013-06-04 00:00:00

abstract：BACKGROUND:We compared the efficacy and safety of different dosages of a low-molecular-weight heparin, CY 216 D (Fraxiparine), in the treatment of submassive pulmonary embolism with unfractionated heparin in a prospective, randomized, dose-finding study. METHODS AND RESULTS:The primary outcome was the evolution of pul...

journal_title：Circulation

authors： Théry C,Simonneau G,Meyer G,Hélénon O,Bridey F,Armagnac C,d'Azemar P,Coquart JP

更新日期：1992-04-01 00:00:00

abstract：:Twelve patients with medically refractory ventricular tachycardia secondary to ischemic heart disease underwent surgery for cure of their arrhythmia. Preoperatively, the tachycardia could be reproducibly initiated and terminated in each patient by programmed stimulation. In all instances, intraoperative mapping locali...

journal_title：Circulation

authors： Josephson ME,Harken AH,Horowitz LN

更新日期：1979-12-01 00:00:00

abstract：:Predictability of prognosis was analyzed in 630 patients who were alive 30 days after valve replacement (1965-1986) for aortic stenosis. Follow-up totaled 4,072 patient-years. During the operative periods of 1965-1971 (n = 62), 1972-1976 (n = 164), 1977-1981 (n = 158), and 1982-1986 (n = 246), decreases in cardiothora...

journal_title：Circulation

authors： Lund O

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Growth of atherosclerotic plaques is accompanied by neovascularization from vasa vasorum microvessels extending through the tunica media into the base of the plaque and by lumen-derived microvessels through the fibrous cap. Microvessels are associated with plaque hemorrhage and may play a role in plaque rupt...

journal_title：Circulation

authors： Moreno PR,Purushothaman KR,Fuster V,Echeverri D,Truszczynska H,Sharma SK,Badimon JJ,O'Connor WN

更新日期：2004-10-05 00:00:00

abstract：:Reperfusion of the previously ischemic myocardium is associated with the production of oxygen free radicals and their metabolites, which contribute to the ultimate extent of irreversible myocardial injury. The relative importance of polymorphonuclear leukocytes vs intracellular-derived oxygen metabolites has remained ...

journal_title：Circulation

authors： Mitsos SE,Askew TE,Fantone JC,Kunkel SL,Abrams GD,Schork A,Lucchesi BR

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Drug-coated balloons (DCBs) have shown promise in improving the outcomes for patients with peripheral artery disease. We compared a paclitaxel-coated balloon with percutaneous transluminal angioplasty (PTA) for the treatment of symptomatic superficial femoral and popliteal artery disease. METHODS AND RESULT...

journal_title：Circulation

authors： Tepe G,Laird J,Schneider P,Brodmann M,Krishnan P,Micari A,Metzger C,Scheinert D,Zeller T,Cohen DJ,Snead DB,Alexander B,Landini M,Jaff MR,IN.PACT SFA Trial Investigators.

更新日期：2015-02-03 00:00:00

abstract：:Lidocaine is a commonly used antiarrhythmic drug that causes use-dependent blockade of sodium channels in vitro and reduces conduction velocity in vitro and in vivo. According to the modulated receptor hypothesis of antiarrhythmic drug action, lidocaine has a low affinity for rested sodium channels but a high affinity...

journal_title：Circulation

authors： Davis J,Matsubara T,Scheinman MM,Katzung B,Hondeghem LH

更新日期：1986-07-01 00:00:00