Influence of gender, age and renal function on plasma adiponectin level: the Tanno and Sobetsu study.

abstract：OBJECTIVE:Herpes simplex virus type 1 (HSV-1)-derived vectors are known to be effective tools to deliver transgenes into normal and neoplastic anterior pituitary (AP) cells in vitro. Our objective was to assess the in vitro and in vivo effects of tsK/beta-gal, a temperature-sensitive HSV-1-derived vector harbouring the...

journal_title：European journal of endocrinology

authors： Bolognani F,Albariño C,Romanowski V,Carri NG,Goya RG

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:In order to better understand how the IGF-I axis is affected by exogenous IGF-I, this study compared the effects of a constant s.c. infusion of IGF-I with that of twice-daily injections of IGF-I in young adult female rhesus monkeys. Clinical studies suggest that circulating concentrations of insulin-like grow...

journal_title：European journal of endocrinology

authors： Wilson ME,Lackey SL

更新日期：1999-09-01 00:00:00

abstract：:Amiodarone (AMD) is a powerful anti-arrhythmic drug used for the treatment of a wide variety of cardiac arrhythmias and its most striking feature is its high iodine content. Thyroid dysfunction is a limiting side-effect of the drug and both AMD-induced hypothyroidism (AIH) and AMD-induced thyrotoxicosis (AIT) are repo...

journal_title：European journal of endocrinology

authors： Pitsiavas V,Smerdely P,Boyages SC

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:Although vascular mortality is increased in hypopituitary adults on routine replacement, there are limited data on the atherosclerotic process during life in these patients. Measurement of arterial stiffness may provide an index of early vascular changes that predispose to the development of major vascular ac...

journal_title：European journal of endocrinology

authors： Markussis V,Beshyah SA,Fisher C,Parker KH,Nicolaides AN,Johnston DG

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Few published data link overweight and obesity with measures of quality of life (QoL) including sexual health in men. OBJECTIVE:To assess the association of overweight/obesity with impairment of physical and psychological QoL and sexual functions in men. DESIGN AND SETTING:Cross-sectional, multicentre surv...

journal_title：European journal of endocrinology

authors： Han TS,Tajar A,O'Neill TW,Jiang M,Bartfai G,Boonen S,Casanueva F,Finn JD,Forti G,Giwercman A,Huhtaniemi IT,Kula K,Pendleton N,Punab M,Silman AJ,Vanderschueren D,Lean ME,Wu FC,EMAS group.

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:Though transsphenoidal surgery remains the first-line treatment of Cushing's disease, recurrence occurs frequently. Conventional radiotherapy and anticortisolic drugs both have adverse effects. Stereotactic radiosurgery needs to be evaluated more precisely. The aim of this study was to determine long-term hor...

journal_title：European journal of endocrinology

authors： Castinetti F,Nagai M,Dufour H,Kuhn JM,Morange I,Jaquet P,Conte-Devolx B,Regis J,Brue T

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:Evidence of the association between vitamin D and cardiovascular risk factors in the young is limited. We therefore assessed the relationships between circulating 25-hydroxyvitamin D(3) (25(OH)D(3)) and metabolic syndrome (MetS), its components, and early atherosclerotic changes in 452 (304 overweight/obese ...

journal_title：European journal of endocrinology

authors： Pacifico L,Anania C,Osborn JF,Ferraro F,Bonci E,Olivero E,Chiesa C

更新日期：2011-10-01 00:00:00

abstract：AIMS:Reported cure rates following trans-sphenoidal surgery for microprolactinoma are variable and recurrence rates in some series are high. We wished to examine the cure rate of trans-sphenoidal surgery for microprolactinoma, and to assess the long-term complications and recurrence rate. DESIGN:A retrospective review...

journal_title：European journal of endocrinology

authors： Turner HE,Adams CB,Wass JA

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:The aromatization of androgenic precursors is the main source of estrogens in postmenopausal women. We tested the hypothesis that allelic variants of the genes coding for aromatase and estrogen receptors (ER) could interact to determine the estrogenic signals on the bone tissue and, consequently, bone mineral...

journal_title：European journal of endocrinology

authors： Riancho JA,Zarrabeitia MT,Valero C,Sañudo C,Mijares V,González-Macías J

更新日期：2006-07-01 00:00:00

abstract：:Glucose transporter-1 (GLUT1) has been found in high abundance in human placentas. The purpose of this study was to analyze the changes in the level of GLUT1 during pregnancy. We have analyzed the gestational changes in human placental GLUT1 by [3H]cytochalasin B binding assay, immunoblot analysis and Northern blot an...

journal_title：European journal of endocrinology

authors： Sakata M,Kurachi H,Imai T,Tadokoro C,Yamaguchi M,Yoshimoto Y,Oka Y,Miyake A

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVES:To examine whether glucagon-like peptide-1 (GLP-1), which has been suggested as a new therapeutic agent in type 2 diabetes, affects circulating islet amyloid polypeptide (IAPP), a B-cell peptide of potential importance for diabetes pathophysiology. DESIGN:GLP-1 was administered in a buccal tablet (400 micro...

journal_title：European journal of endocrinology

authors： Ahrén B,Gutniak M

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:Prolactin is capable of both trophic and lytic actions in rat corpora lutea. In corpora lutea responding to a trophic prolactin signal, the long form of the prolactin receptor is the dominant form and is upregulated by prolactin. We investigated whether mRNA for the short form of the prolactin receptor was do...

journal_title：European journal of endocrinology

authors： Bowen JM,Telleria CM,Towns R,Keyes PL

更新日期：2000-08-01 00:00:00

abstract：:Low levels of insulin-like growth factor I (IGF-I) in critical illness are observed despite increased or normal levels of growth hormone (GH). The mechanisms for this apparent GH resistance have not been elucidated. As many of the acute inflammatory responses in critical illness are mediated by the proinflammatory cyt...

journal_title：European journal of endocrinology

authors： Wolf M,Böhm S,Brand M,Kreymann G

更新日期：1996-12-01 00:00:00

abstract：:Deflazacort is an oxazoline derivative of cortisone with presumably less serious side effects, but its effects on growth factors are unknown. The present experiments in Long Evans rats were carried out to investigate how deflazacort administration affected the growing rat, especially in relation to hepatic insulin-lik...

journal_title：European journal of endocrinology

authors： Latta K,Krieg RJ Jr,Chan W,Hisano S,Chan JC

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:Flushing can be defined as a sensation of warmth accompanied by erythema that most commonly is seen on the face and which occurs in episodic attacks. Such a problem can be clinically problematic, since many conditions and drugs can be related to flushing, and while often there appears to be no underlying orga...

journal_title：European journal of endocrinology

authors： Huguet I,Grossman A

更新日期：2017-11-01 00:00:00

abstract：:The aim of this study was to investigate the frequencies of clinical diabetes and humoral markers of anti-pancreatic autoimmunity in a homogeneous population of 600 Caucasian patients with recently diagnosed Graves' disease (GD), in order to characterize the specific features of this group of endocrine patients among ...

journal_title：European journal of endocrinology

authors： Maugendre D,Vérité F,Guilhem I,Genetet B,Allannic H,Delamaire M

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:In order to characterize urinary gonadotropin peptide (UGP) as an acute phase reactant, we focused on the UGP levels after surgical operation. DESIGN:Fifty cases of gastrointestinal cancer, 4 cases of cancers of other organs and 13 cases of benign digestive diseases were enrolled into this study. METHODS:UG...

journal_title：European journal of endocrinology

authors： Motoo Y,Watanabe H,Okai T,Sawabu N

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:Makorin ring finger protein 3 (MKRN3) gene restrains the hypothalamic-pituitary-gonadal axis. In girls, peripheral levels of MKRN3 decline prior to the onset of puberty. We described longitudinal changes in serum MKRN3 levels in boys before and during puberty and assessed the effect of inhibition of estrogen ...

journal_title：European journal of endocrinology

authors： Varimo T,Dunkel L,Vaaralahti K,Miettinen PJ,Hero M,Raivio T

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Cross-sectional studies have shown that more than 50% of patients with congestive heart failure (CHF) have decreased bone mineral density (BMD). There is limited knowledge about the longitudinal changes of BMD and how to treat bone loss in patients with CHF. METHODS:The present study was a prospective, long...

journal_title：European journal of endocrinology

authors： Frost RJ,Sonne C,Wehr U,Stempfle HU

更新日期：2007-03-01 00:00:00

abstract：:Objective To explore whether gestational prolactin and breast increase are markers of metabolic health in pregnancy and on long-term, in PCOS. Design Follow-up study. Women with PCOS, according to the Rotterdam criteria (n = 239), former participants of the randomized controlled trial (RCT) PregMet were invited, 131 p...

journal_title：European journal of endocrinology

authors： Underdal MO,Salvesen Ø,Schmedes A,Andersen MS,Vanky E

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:Untreated hypothyroidism is common in iodine-replete areas. Frequent thyroid function testing and use of levothyroxine treatment for subclinical hypothyroidism suggest that the prevalence may have decreased. Therefore, in this study, we examined changes in the prevalence of hypothyroidism in a Norwegian count...

journal_title：European journal of endocrinology

authors： Asvold BO,Vatten LJ,Bjøro T

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Previous studies have suggested that infections are an important cause of death in patients with Addison's disease, but epidemiological studies on the frequency of infections in this population are lacking. OBJECTIVE:To assess and compare the incidence risk of infections in patients with primary adrenal ins...

journal_title：European journal of endocrinology

authors： Smans LC,Souverein PC,Leufkens HG,Hoepelman AI,Zelissen PM

更新日期：2013-03-15 00:00:00

abstract：:Glucocorticoids (GC) such as cortisol regulate multiple physiological functions, notably those involved in development, metabolism, inflammatory processes and stress, and exert their effects upon binding to the glucocorticoid receptor (GR, encoded by NR3C1 gene in humans). GC signaling follows several consecutive step...

journal_title：European journal of endocrinology

authors： Vitellius G,Lombes M

更新日期：2020-02-01 00:00:00

abstract：:We report the clinical history and results of endocrine investigations in two brothers born to consanguineous parents, who presented with hypokalemia and arterial hypertension when they were aged 2 and 6 years. The hormonal serum assay results, including extremely low values for aldosterone and plasma renin activity, ...

journal_title：European journal of endocrinology

authors： Gourmelen M,Saint-Jacques I,Morineau G,Soliman H,Julien R,Fiet J

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:Patients with craniopharyngioma are at an increased risk for cardio- and cerebrovascular mortality. The metabolic syndrome (MetS) is an important cardiometabolic risk factor, but barely studied in patients with craniopharyngioma. We aimed to investigate the prevalence of and risk factors for the MetS and its ...

journal_title：European journal of endocrinology

authors： Wijnen M,Olsson DS,van den Heuvel-Eibrink MM,Hammarstrand C,Janssen JAMJL,van der Lely AJ,Johannsson G,Neggers SJCMM

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Estimates of the prevalence of hypothyroidism in unselected populations date from the late 1990s. We present an update on the prevalence and incidence of overt hypothyroidism in Piedmont, northwest Italy and examine the association between hypothyroidism and multiple chronic comorbidities. DESIGN AND METHODS...

journal_title：European journal of endocrinology

authors： Giorda CB,Carnà P,Romeo F,Costa G,Tartaglino B,Gnavi R

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:GH deficiency (GHD) and glucocorticoid excess are associated with increased risk of fragility fractures. We aimed to evaluate whether the prevalence of vertebral fractures may be influenced by glucocorticoid over-replacement in hypopituitary males with GHD. DESIGN:Cross-sectional study. METHODS:Fifty-one ad...

journal_title：European journal of endocrinology

authors： Mazziotti G,Porcelli T,Bianchi A,Cimino V,Patelli I,Mejia C,Fusco A,Giampietro A,De Marinis L,Giustina A

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:In malnutrition both the GH-IGF and reproductive axes are greatly affected. Because the actions of IGF and sex steroids are inter-dependent in many tissues, we have examined how ovariectomy modulates the response of the systemic IGF system to undernutrition. DESIGN AND METHODS:Peripubertal (30 days of age) f...

journal_title：European journal of endocrinology

authors： Goya L,García-Segura LM,Ramos S,Pascual-Leone AM,Argente J,Martín MA,Chowen JA

更新日期：2002-09-01 00:00:00

abstract：:There is increasing evidence that ovarian steroids inhibit vascular responsiveness to the neurohypophysial hormone vasopressin. The present study examined the recovery of the arterial blood pressure following a single (2 ml/100 g body weight) haemorrhage in ovariectomized (OVX) Brattleboro rats with hereditary hypotha...

journal_title：European journal of endocrinology

authors： Morrissey SE,Edwards TJ,Wilson KJ,Whitehead SA,Laycock JF

更新日期：1997-03-01 00:00:00

abstract：:Nitric oxide mediates a wide array of cellular functions in many tissues. It is generated by three known isoforms of nitric oxide synthases (NOS). Recently, the endothelial isoform, NOSIII, was shown to be abundantly expressed in the rat thyroid gland and its expression increased in goitrous glands. In this study, we ...

journal_title：European journal of endocrinology

authors： Colin IM,Kopp P,Zbären J,Häberli A,Grizzle WE,Jameson JL

更新日期：1997-06-01 00:00:00