Receptive-field structure of direction-selective ganglion cells projecting to the goldfish tectum.

abstract：:The availability of new food composition carotenoid values for fruits and vegetables increases our ability to test hypotheses concerning the role of antioxidant nutrients and cancer risk. To estimate the usual carotenoid intakes, a quantitative diet history covering a one-year period is recommended for epidemiologic s...

journal_title：Annals of the New York Academy of Sciences

authors： Hankin JH,Le Marchand L,Kolonel LN,Wilkens LR

更新日期：1993-12-31 00:00:00

abstract：:In the early 1970s carbohydrates (CHOs) were believed to induce overconsumption and excess fat deposition. They are now perceived to protect against these consequences. This paper evaluates the evidence for this change of interpretation by considering (1) the energy content of CHOs, (2) the energetic efficiency with w...

journal_title：Annals of the New York Academy of Sciences

authors： Stubbs RJ,Prentice AM,James WP

更新日期：1997-05-23 00:00:00

abstract：:Nephroblastoma overexpressed (Nov), a member of the CCN family of proteins, is expressed by osteoblasts and its transcription is regulated by transforming growth factor (TGF)-beta and bone morphogenetic proteins (BMP). CCN proteins can interact with TGF-beta, BMPs, and Wnt. We explored the function of Nov in skeletal ...

journal_title：Annals of the New York Academy of Sciences

authors： Canalis E

更新日期：2007-11-01 00:00:00

abstract：:Differentiation of embryonic stem (ES) cells in vitro yields abundant hematopoietic progenitors, but achieving stable hematopoietic engraftment of irradiated mice has proven difficult, begging the question of whether ES cells give rise to hematopoietic stem cells in vitro, and limiting the application of ES cells as e...

journal_title：Annals of the New York Academy of Sciences

authors： Daley GQ

更新日期：2003-05-01 00:00:00

abstract：:Calcitonin gene-related peptide has been identified by immunocytochemistry within the thymus of fetal through aged adult mice. Calcitonin gene-related peptide positive nerves are observed from embryonic day 17 throughout the lifespan of the mouse. A sparse cell population positive for CGRP is first observed during the...

journal_title：Annals of the New York Academy of Sciences

authors： Bulloch K,McEwen BS,Diwa A,Radojcic T,Hausman J,Baird S

更新日期：1994-11-25 00:00:00

abstract：:Patients with probable Alzheimer's disease were either stimulated with a continuous visual recognition task (n = 18) or with a continuous auditory recognition task during PET measurement with 18 FDG. The PET scanner was a Siemens CTI, ECAT EXACT with 5 mm transaxial and 6 mm axial resolution. The global stimulation ef...

journal_title：Annals of the New York Academy of Sciences

authors： Kessler J,Ghaemi M,Mielke R,Herholz K,Heiss WD

更新日期：1996-01-17 00:00:00

abstract：:Esophageal squamous cell carcinoma (ESCC) is one of the most predominant malignancies worldwide. The 5-year survival rate is still relatively low due to few symptoms presenting with the early disease, diagnosis at middle to late stage, and high risk of recurrence after therapy. Novel protein biomarkers for early detec...

journal_title：Annals of the New York Academy of Sciences

authors： Wang M,Smith JS,Wei WQ

更新日期：2018-12-01 00:00:00

abstract：:The advent of highly active anti-retroviral therapy (HAART) has dramatically decreased the rate of AIDS-related mortality and significantly extended the life span of patients with AIDS. A variety of metabolic side effects are associated with these therapies, one of which is metabolic bone disease. A higher prevalence ...

journal_title：Annals of the New York Academy of Sciences

authors： Pan G,Yang Z,Ballinger SW,McDonald JM

更新日期：2006-04-01 00:00:00

abstract：:The course of 1,487 patients with myasthenia gravis followed between 1940 and 1985 for a mean of 18 years provides further evidence that the distribution, severity, and outcome of the disease are determined during the first 1 to 3 (occasionally 5) years after onset, suggesting that injury to acetylcholine receptors oc...

journal_title：Annals of the New York Academy of Sciences

authors： Grob D,Arsura EL,Brunner NG,Namba T

更新日期：1987-01-01 00:00:00

abstract：:The computation of ITD begins with preservation of the phase angle of spectral components by eighth-nerve fibers and by cells of the nucleus magnocellularis. At the level of the nucleus laminaris, the difference in phase angle of corresponding spectral components in the left and right ears is extracted. At the next le...

journal_title：Annals of the New York Academy of Sciences

authors： Takahashi TT

更新日期：1989-01-01 00:00:00

abstract：:Judicious selection of new animal models for the study of basic aging processes must combine feasibility and good use of the comparative method with evidence of antiaging adaptations, like the ability to combat oxidative damage to cells and tissues. A number of vertebrate species already in use or being developed as n...

journal_title：Annals of the New York Academy of Sciences

authors： Holmes DJ

更新日期：2004-06-01 00:00:00

abstract：:Every day billions of cells die in our bodies to eliminate those that are harmful, useless, or senescent. The process can be divided into two steps: cell dying and cell clearance. In the first step, death machinery is activated in the cells and quickly kills them. During the second step, dead cells are engulfed by pha...

journal_title：Annals of the New York Academy of Sciences

authors： Nagata S

更新日期：2010-10-01 00:00:00

abstract：:The present study investigates the impact of emotional deficits on implicit and explicit memory for musical stimuli in patients with Alzheimer's disease and elderly depressed patients. Results showed that unlike Alzheimer's patients, depressed patients were unable to develop a positive affective bias of judgment for p...

journal_title：Annals of the New York Academy of Sciences

authors： Quoniam N,Ergis AM,Fossati P,Peretz I,Samson S,Sarazin M,Allilaire JF

更新日期：2003-11-01 00:00:00

abstract：:The rat displays three behaviors when surface and/or deep body temperatures rise above their normal levels: grooming, which spreads saliva over the fur to cool by evaporation; locomotion, which results in escape to a cooler environment; and relaxed postural extension, which reduces heat production by muscle activity a...

journal_title：Annals of the New York Academy of Sciences

authors： Roberts WW

更新日期：1988-01-01 00:00:00

abstract：:For more than 10 years umbilical cord blood (UCB) has been used as an alternative source of hematopoietic stem cells for allogeneic transplantation. Although the clinical results are encouraging, UCB is associated with delayed engraftment. To address these issues we have used the NOD/SCID mouse model to study the engr...

journal_title：Annals of the New York Academy of Sciences

authors： Fibbe WE,Noort WA,Schipper F,Willemze R

更新日期：2001-06-01 00:00:00

abstract：:Long-term changes in catecholamine levels and expression of their biosynthetic enzymes are associated with several stress-related disorders such as elevated plasma norepinephrine in posttraumatic stress disorder and increased postmortem tyrosine hydroxylase in the locus coeruleus with major depression. Stress elevates...

journal_title：Annals of the New York Academy of Sciences

authors： Sabban EL,Hebert MA,Liu X,Nankova B,Serova L

更新日期：2004-12-01 00:00:00

abstract：:MRI assessment of myocardial iron and function has revolutionized the treatment of thalassemia major patients. While knowledge of somatic iron stores is vital for iron chelation management, it does not adequately monitor cardiac risk. MRI monitoring of cardiac T2* allows preclinical recognition of myocardial iron, str...

journal_title：Annals of the New York Academy of Sciences

authors： Wood JC,Noetzli L

更新日期：2010-08-01 00:00:00

abstract：:The objective of this double-blind, placebo-controlled, dose-escalation study is to evaluate safety, tolerability, and enhancement on healing of thymosin beta-4 (Tbeta-4) administered topically in patients with venous ulcers. Three groups of patients, coming from 10 sites, 5 from Italy and 5 from Poland, will be enrol...

journal_title：Annals of the New York Academy of Sciences

authors： Guarnera G,DE Rosa A,Camerini R

更新日期：2007-09-01 00:00:00

abstract：:Blood-borne beta-amyloids (A beta s) could affect brain function by (1) crossing the BBB to directly interact with brain tissues or (2) altering BBB function by interacting with the brain capillaries that make up the BBB. Several radioactively labeled A beta s have been examined for such interactions. Blood-borne A be...

journal_title：Annals of the New York Academy of Sciences

authors： Banks WA,Kastin AJ,Maness LM,Banks MF,Shayo M,McLay RN

更新日期：1997-09-26 00:00:00

abstract：:Moderated by Lisa Miller from Newsweek, evolutionary biologist Kenneth Miller (Brown University) and theologians John Haught (Georgetown University) and Nancey Murphy (Fuller Theological Seminary) discuss the questions Are we immortal? Do our souls exist beyond our bodies? and What scientific evidence is there for mys...

journal_title：Annals of the New York Academy of Sciences

authors： Miller L,Miller K,Haught J,Murphy N

更新日期：2011-10-01 00:00:00

abstract：:The risk of cardiovascular (CV) disease increases in patients with rheumatoid arthritis (RA). This is due to a number of different triggers including traditional and disease-related factors. Among established risk factors for CV disease, smoking may exert a more dangerous effect on arterial wall in RA than in the gene...

journal_title：Annals of the New York Academy of Sciences

authors： Gerli R,Sherer Y,Bocci EB,Vaudo G,Moscatelli S,Shoenfeld Y

更新日期：2007-06-01 00:00:00

abstract：:According to a current paradigm cardiovascular diseases can be initiated by exposure of vascular cells to qualitatively modified low-density lipoproteins (LDL). Capillary leakage, an early feature of diabetic retinopathy, results in the exposure of retinal pericytes to modified LDL, including glycated (G-LDL) and heav...

journal_title：Annals of the New York Academy of Sciences

authors： Song W,Barth JL,Lu K,Yu Y,Huang Y,Gittinger CK,Argraves WS,Lyons TJ

更新日期：2005-06-01 00:00:00

abstract：:Evidence is reviewed that suggests a central role for telomeres in one major model of biological aging, namely, proliferative senescence. Telomeric shortening with each cell division does not only act as a biological clock, but appears to trigger the ultimate loss of proliferative ability via activation of the p53-dep...

journal_title：Annals of the New York Academy of Sciences

authors： von Zglinicki T

更新日期：1998-11-20 00:00:00

abstract：:Rapid cooling of small samples is necessary both to cryofixation for electron microscopy and to vitrification for cryopreservation. Several effects on the cooling rates of small samples quenched into liquid nitrogen were studied, including the diameter of samples, the subcooling of liquid nitrogen, the quenching speed...

journal_title：Annals of the New York Academy of Sciences

authors： Cao Q,Hua TC

更新日期：1998-09-11 00:00:00

abstract：:Indirect evidence suggests that dopamine within the brain may participate in the regulation of immune responses in both man and rodents. The aim of the present study was to investigate the possible role played by the specific dopamine D1 receptor subtype within the central amygdala in the modulation of immunity. Mitog...

journal_title：Annals of the New York Academy of Sciences

authors： Nistico G,Caroleo MC,Arbitrio M,Pulvirenti L

更新日期：1994-11-25 00:00:00

abstract：:Biologics are playing an increasingly significant role in the practice of modern medicine and surgery in general and orthopedics in particular. Cell-based approaches are among the most important and widely used modalities in orthopedic biologics, with mesenchymal stem cells and other multi/pluripotent cells undergoing...

journal_title：Annals of the New York Academy of Sciences

authors： Lebaschi A,Nakagawa Y,Wada S,Cong GT,Rodeo SA

更新日期：2017-12-01 00:00:00

abstract：:Members of the steroid receptor superfamily, like other transcription factors, can function as transcriptional inducers as well as repressors of transcription. The mechanisms by which repression is achieved seem to be specific for the factors and [table: see text] regulatory sequences involved. Many and perhaps all of...

journal_title：Annals of the New York Academy of Sciences

authors： Renkawitz R

更新日期：1993-06-11 00:00:00

abstract：:The primary objective of this review is to suggest a major role of cytogenetic pathology in the genesis of both the neoplastic phenotype and the senescent phenotype of aging mammalian organisms. It is hypothesized that allelic variation at a number of genetic loci that have the potential to modulate various types of c...

journal_title：Annals of the New York Academy of Sciences

authors： Martin GM

更新日期：1991-01-01 00:00:00

abstract：:Content differentiation models posit that different areas of the prefrontal cortex perform similar operations but differ in terms of the content that is operated on. For example, it has been suggested that the orbitofrontal cortex (OFC) and the dorsolateral prefrontal cortex (DLPFC) perform similar working memory or i...

journal_title：Annals of the New York Academy of Sciences

authors： Zald DH

更新日期：2007-12-01 00:00:00

abstract：:Epidemiological observations, clinical mechanistic studies, and basic laboratory research suggest that estrogen therapy is associated with beneficial cardiovascular effects in postmenopausal women. Estrogen has a multitude of biological effects that may account for this apparent benefit (which remains to be proved in ...

journal_title：Annals of the New York Academy of Sciences

authors： Blum A,Cannon RO 3rd

更新日期：2001-12-01 00:00:00