Effects on CYP27 mRNA expression in rat kidney and liver by 1 alpha, 25-dihydroxyvitamin D3, a suppressor of renal 25-hydroxyvitamin D3 1 alpha-hydroxylase activity.

abstract：:Ribose methylation of eukaryotic rRNA is directed by box C/D small nucleolar RNAs (snoRNAs), which pinpoint the nucleotide to be methylated in specific position within the rRNA sequence. Here, we report the identification of a novel double-guide C/D box snoRNA termed snR88 that directs methylation of two previously un...

journal_title：Biochemical and biophysical research communications

authors： Bi YZ,Qu LH,Zhou H

更新日期：2007-03-02 00:00:00

abstract：:Olfactory adaptation requires the change of intracellular calcium concentration during stimuli. To contribute in the study of the molecular mechanism of calcium-dependent regulations in olfactory receptor cells, we isolated a novel 26-kDa Ca2+-binding protein named p26olf from the frog olfactory epithelium after four ...

journal_title：Biochemical and biophysical research communications

authors： Miwa N,Kobayashi M,Takamatsu K,Kawamura S

更新日期：1998-10-29 00:00:00

abstract：:Hrp3, a paralog of Hrp1, is a novel member of the CHD1 (chromo-helicase/ATPase-DNA binding 1) protein family of Schizosaccharomyces pombe. Although it has been considered that CHD1 proteins are required for chromatin modifications in transcriptional regulations, little is known about their roles in vivo. In this study...

journal_title：Biochemical and biophysical research communications

authors： Jae Yoo E,Kyu Jang Y,Ae Lee M,Bjerling P,Bum Kim J,Ekwall K,Hyun Seong R,Dai Park S

更新日期：2002-07-26 00:00:00

abstract：:Severe cold exposure and pressure overload are both known to prompt oxidative stress and pathological alterations in the heart although the interplay between the two remains elusive. Transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel activated in response to a variety of exogenous and en...

journal_title：Biochemical and biophysical research communications

authors： Lu S,Xu D

更新日期：2013-12-06 00:00:00

abstract：:Receptor activator of NF-κB ligand (RANKL) is a member of the TNF superfamily. RANKL increases endothelial permeability and induces angiogenesis, suggesting its critical roles in the vasculature. Despite the evidence implicating RANKL in vascular pathology, its role in ischemic retinopathy has not been previously repo...

journal_title：Biochemical and biophysical research communications

authors： Ock S,Park S,Lee J,Kim J

更新日期：2019-08-20 00:00:00

abstract：:The endoplasmic reticulum (ER) is an organelle in which most membrane and secretory proteins are synthesized. If these proteins are not folded correctly, unfolded proteins accumulate in the ER lumen, causing a cellular situation known as ER stress. Recently, many studies on the relationship between ER stress and disea...

journal_title：Biochemical and biophysical research communications

authors： Hosoda A,Maruyama A,Oikawa D,Oshima Y,Komachi Y,Kanai G,Sato H,Iwawaki T

更新日期：2011-02-04 00:00:00

abstract：:The activation of caspase-3 is a key surrogate marker for detecting apoptosis. To quantitate caspase-3 activity, we constructed a biosensor comprising a recombinant firefly luciferase containing a caspase-3 cleavage site. When apoptosis was induced, caspase-3 cleavage of the biosensor activated firefly luciferase by a...

journal_title：Biochemical and biophysical research communications

authors： Shi J,Zhang H,Fang L,Xi Y,Zhou Y,Luo R,Wang D,Xiao S,Chen H

更新日期：2014-10-03 00:00:00

abstract：:Electrofocusing of mouse small intestine mucosal cytosol yielded two prominent peaks of glutathione S-transferase activity, at pH 8.7 and pH 9.0. These intestinal transferases were indistinguishable from corresponding liver transferases in immunological reactivities and in several other properties. Dietary t-butyl-4-h...

journal_title：Biochemical and biophysical research communications

authors： Parchment RE,Benson AM

更新日期：1984-03-30 00:00:00

abstract：:The Fru-6-P/Fru-2,6-P2 exchange reaction of rat liver 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase was almost entirely dependent on the presence of Pi. This exchange was not due to a reversal of the bisphosphatase nor to trace amounts of adenine nucleotide in the enzyme. Exchange activity was maximal at pH 7, ...

journal_title：Biochemical and biophysical research communications

authors： El-Maghrabi MR,Pate TM,Pilkis SJ

更新日期：1984-09-17 00:00:00

abstract：:Chondroitin sulfate proteoglycan 4 (CSPG4), a transmembrane proteoglycan originally identified in melanoma cells, has been reported to be expressed in breast cancer cells. This study was performed to examine the expression and significance of CSPG4 in a cohort of breast cancer patients. Immunohistochemical analysis of...

journal_title：Biochemical and biophysical research communications

authors： Hsu NC,Nien PY,Yokoyama KK,Chu PY,Hou MF

更新日期：2013-11-15 00:00:00

abstract：:In the central nervous system of 11.5-day mouse embryos, the expression of CRABP was spatially restricted to the anteroposterior axis. CRABP was most strongly expressed in the rhombencephalon and the anterior part of the neural tube. In 14-day mouse embryo, CRABP drastically decreased in the brain and the anterior par...

journal_title：Biochemical and biophysical research communications

authors： Momoi T,Hanaoka K,Momoi M

更新日期：1990-06-29 00:00:00

abstract：:In this study, we use HRMAS NMR as a non-invasive technique to monitor the in vivo metabolism of a xenobiotic. The antituberculosis Ethionamide is a pro-drug that has to be activated in mycobacteria before inhibiting its cellular target. The use of (1)H HRMAS NMR has allowed to detect a metabolite (ETH*) of the drug d...

journal_title：Biochemical and biophysical research communications

authors： Hanoulle X,Wieruszeski JM,Rousselot-Pailley P,Landrieu I,Baulard AR,Lippens G

更新日期：2005-06-03 00:00:00

abstract：:miRNAs are recently found playing important roles in osteogenesis. In this study, we identified that miR-222-3p decreased during osteogenic differentiation of human mesenchymal stem cells (hBMSCs) using Quantitative Real-Time Reverse Transcription PCR (qRT-PCR). Furthermore, we investigated the effect of miR-222-3p on...

journal_title：Biochemical and biophysical research communications

authors： Yan J,Guo D,Yang S,Sun H,Wu B,Zhou D

更新日期：2016-02-12 00:00:00

abstract：:Depression is a common psychiatric disorder that affects millions of people around the world, however, little is known about the pathophysiology of depression and the therapeutic strategy for anti-depression. In this study, we investigated the role of irisin, a regulator of energy metabolism, in the modulation of depr...

journal_title：Biochemical and biophysical research communications

authors： Wang S,Pan J

更新日期：2016-05-20 00:00:00

abstract：:Factors affecting Ins(1,3,4,5)P4-mediated nuclear Ca2+ uptake are investigated, which include Ins(1,3,4,5)P4 receptor ligand specificity and free external Ca2+ concentrations. Among various inositol phosphates examined, Ins(1,3,4,5)P4, Ins(3,4,5,6)P4, and Ins(1,3,4,5,6)P5 can also stimulate 45Ca2+ influx into isolated...

journal_title：Biochemical and biophysical research communications

authors： Hsu AL,Lu PJ,Chen CS

更新日期：1998-02-24 00:00:00

abstract：:The human leukemia cell line KU812 had been described as an immature prebasophilic cell line and exhibits a potential to differentiate into mature basophils. We studied the effect of interleukin-4 (IL-4) on the basophilic differentiation of KU812 cells. When KU812 cells were cultured with 1 ng/ml IL-4, cellular histam...

journal_title：Biochemical and biophysical research communications

authors： Hara T,Yamada K,Tachibana H

更新日期：1998-06-29 00:00:00

abstract：:Triple negative breast cancer (TNBC) is the hardest breast cancer subtype to treat due to lacking therapeutic target and treatment options. In this study, we found that SLUG expression was much higher in TNBC MDA-MB-231 cells than estrogen receptor alpha (ERα) positive breast cancer MCF7 cells. 4-hydroxytamoxifen (4-O...

journal_title：Biochemical and biophysical research communications

authors： Geng C,Li J,Ding F,Wu G,Yang Q,Sun Y,Zhang Z,Dong T,Tian X

更新日期：2016-04-22 00:00:00

abstract：:Expression of the MHC class I chain related molecules A and B (MICA/B) on tumor cell surface can signal the immune receptor NKG2D for tumor immune destruction. However, MIC was found to be shed by tumors in cancer patients, which negatively regulates host immunity and promotes tumor immune evasion and progression. The...

journal_title：Biochemical and biophysical research communications

authors： Wang X,Lundgren AD,Singh P,Goodlett DR,Plymate SR,Wu JD

更新日期：2009-09-25 00:00:00

abstract：:Recombination in a bovine papillomavirus shuttle vector carrying direct repeats of Moloney murine leukemia virus LTR sequence was examined. Differently from similar vectors carrying direct repeats of SV40 polyA addition signal or neomycin resistance gene, the vector exhibited no homologous recombination between the re...

journal_title：Biochemical and biophysical research communications

authors： Kitamura Y,Naito A,Yoshikura H

更新日期：1991-08-30 00:00:00

abstract：:alpha-Difluoromethylornithine (DFMO) has been widely used for determining the amounts of ornithine decarboxylase (ODC) in cells. However, we have now found that DFMO does not react with ODC-antizyme complex, indicating that the amounts of radioactive DFMO bound to the protein may not reflect the amounts of ODC in crud...

journal_title：Biochemical and biophysical research communications

authors： Kitani T,Fujisawa H

更新日期：1986-06-30 00:00:00

abstract：:Histamine H3 receptor (H3R), one of G protein-coupled receptors (GPCRs), has been known to regulate neurotransmitter release negatively in central and peripheral nervous systems. Recently, a variety of intracellular proteins have been identified to interact with carboxy (C)-termini of GPCRs, and control their intracel...

journal_title：Biochemical and biophysical research communications

authors： Maeda K,Haraguchi M,Kuramasu A,Sato T,Ariake K,Sakagami H,Kondo H,Yanai K,Fukunaga K,Yanagisawa T,Sukegawa J

更新日期：2008-05-02 00:00:00

abstract：:To test the hypothesis that ferroxidase I (ceruloplasmin) activity is essential for iron mobilization, adult rats were fed a copper sufficient diet with or without the chelating drugs D-penicillamine and triethylenetetramine for 120 days. By day 6 of treatment and for the remainder of the experiment the drug-fed rats ...

journal_title：Biochemical and biophysical research communications

authors： Cohen NL,Keen CL,Lönnerdal B,Hurley LS

更新日期：1983-05-31 00:00:00

abstract：:A fragment of human gene for pregnancy-specific beta 1-glycoprotein(s), recently identified CEA family member(s), has been cloned. Analyses of nucleotide and deduced amino acid sequences revealed that it carried, from 5' to 3' direction, exons IA, IB, IIA, IIB, C3, C1 and C2, the first four encoding peptides distinct ...

journal_title：Biochemical and biophysical research communications

authors： Oikawa S,Inuzuka C,Kosaki G,Nakazato H

更新日期：1988-10-14 00:00:00

abstract：:Various subclasses of messenger ribonucleoprotein particles were prepared from free cytoplasmic and polysome fractions of rat liver on the basis of the homopolymeric content of the constituent RNA's. Two major proteins were evident in the free cytoplasmic preparations: the poly(A)-binding protein was the major constit...

journal_title：Biochemical and biophysical research communications

authors： Ford G,Nichols JL

更新日期：1984-05-16 00:00:00

abstract：:Expression of the human beta-myosin heavy chain (beta MHC) gene was studied by transient assay in culture and in situ by direct injection of plasmids into adult rat hearts. In this report we describe a unique repressor region located -326/-309 (5'-TTGGTGGTCGTGGTCAGT-3') of the human beta MHC gene that is conserved amo...

journal_title：Biochemical and biophysical research communications

authors： Edwards JG,Bahl JJ,Flink I,Milavetz J,Goldman S,Morkin E

更新日期：1992-11-30 00:00:00

abstract：:We examined the mechanism of arachidonate release induced by somatostatin-14 (SS14) in CHO-K1 cells overexpressing rat hippocampal somatostatin receptor SSTR4. SSTR4 couples to pertussis toxin (PTX)-sensitive G-protein in CHO cells and does not lead to phosphoinositides breakdown or intracellular calcium ([Ca2+]i) mob...

journal_title：Biochemical and biophysical research communications

authors： Sakanaka C,Ferby I,Waga I,Bito H,Shimizu T

更新日期：1994-11-30 00:00:00

abstract：:When human peripheral monocytes and rabbit peritoneal macrophages were incubated with hyaluronic acid, the media were found to contain interleukin-1 (IL-1) activity and to stimulate collagenase production by rabbit fibroblasts. A digestion of hyaluronic acid by testicular hyaluronidase decreased the IL-1 inducing acti...

journal_title：Biochemical and biophysical research communications

authors： Hiro D,Ito A,Matsuta K,Mori Y

更新日期：1986-10-30 00:00:00

abstract：:Nowadays, connexin (Cx) 36 is considered the sole gap junction protein expressed in pancreatic beta cells. In the present research we investigated the expression of Cx30.2 mRNA and protein in mouse pancreatic islets. Cx30.2 mRNA and protein were identified in isolated islet preparations by qRT-PCR and Western blot, re...

journal_title：Biochemical and biophysical research communications

authors： Coronel-Cruz C,Hernández-Tellez B,López-Vancell R,López-Vidal Y,Berumen J,Castell A,Pérez-Armendariz EM

更新日期：2013-09-06 00:00:00

abstract：:Non-photochemical quenching (NPQ) is the most important photoprotective system in higher plants. NPQ can be divided into several steps according to the timescale of relaxation of chlorophyll fluorescence after reaching a steady state (i.e., the fast phase, qE; middle phase, qZ or qT; and slow phase, qI). The dissipati...

journal_title：Biochemical and biophysical research communications

authors： Kohzuma K,Hikosaka K

更新日期：2018-03-25 00:00:00

abstract：:IL-17 plays an important role in gut homeostasis. However, the role of IL-17F in intestinal tumorigenesis has not been addressed. Here we demonstrate that ablation of IL-17F significantly inhibits spontaneous intestinal tumorigenesis in the small intestine of Apc(Min/+) mice. IL-17F ablation decreased IL-1β and Cox-2 ...

journal_title：Biochemical and biophysical research communications

authors： Chae WJ,Bothwell AL

更新日期：2011-10-14 00:00:00