Mechanisms of increased myocardial contractility with hypertonic saline solutions in isolated blood-perfused rabbit hearts.

abstract：UNLABELLED:It is generally accepted that major surgery is associated with severe alterations of the host-defense mechanisms. We investigated the effect of surgical stress on the immune system. Specifically, we studied the relationship between perioperative lipopolysaccharide (LPS) hyporesponsiveness and monocyte human ...

journal_title：Anesthesia and analgesia

authors： Kawasaki T,Ogata M,Kawasaki C,Tomihisa T,Okamoto K,Shigematsu A

更新日期：2001-05-01 00:00:00

abstract：:Agreement between estimated fibrinogen concentration via thromboelastography and traditional assays is not established in the parturient. We therefore recruited 56 parturients and performed Clauss and functional fibrinogen level (FLEV) tests. Mean difference of measurements was 36.8 mg/dL (95% CI, 21.8-51.9) with a st...

journal_title：Anesthesia and analgesia

authors： Katz D,Hamburger J,Batt D,Zahn J,Beilin Y

更新日期：2019-09-01 00:00:00

abstract：:The aim of the present study was to investigate the impact of isoflurane on regional neurogenic mechanisms in the control of vascular tone. Therefore, regional determinations of sympathetic activity and hemodynamics were made in chloralose-anesthetized swine before and during administration of 1.4% isoflurane. Sympath...

journal_title：Anesthesia and analgesia

authors： Aneman A,Pontén J,Fändriks L,Eisenhofer G,Friberg P,Biber B

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:β3 containing γ-aminobutyric acid type A receptors (GABA(A)-Rs) mediate behavioral end points of IV anesthetics such as immobility and hypnosis. A knockout mouse with targeted forebrain deletion of the β3 subunit of the GABA(A)-R shows reduced sensitivity to the hypnotic effect of etomidate, as measured by t...

journal_title：Anesthesia and analgesia

authors： Rau V,Oh I,Liao M,Bodarky C,Fanselow MS,Homanics GE,Sonner JM,Eger EI 2nd

更新日期：2011-09-01 00:00:00

abstract：UNLABELLED:Pain on injection of propofol continues to be a problem for anesthesiologists. A lipid-free formulation of propofol and a propofol emulsion containing medium-chain triglyceride have become available in the Indian market. We performed this study to assess the pain on injection of propofol emulsion containing ...

journal_title：Anesthesia and analgesia

authors： Dubey PK,Kumar A

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:The American Society of Anesthesiologists has announced that perioperative normothermia is a "Quality Incentive in Anesthesiology." We examined whether we could meet this quality incentive in a simple population: patients undergoing anesthesia for electroconvulsive therapy (ECT). METHODS:We compared infrare...

journal_title：Anesthesia and analgesia

authors： Modell JH,Gravenstein N,Morey TE

更新日期：2008-11-01 00:00:00

abstract：:The effects of induction of anesthesia with diazepam and midazolam on baroreflex control of heart rate and on plasma levels of catecholamines were investigated in this study. Group 1 subjects (n = 10) received diazepam, 0.4 mg/kg. Group 2 subjects (n = 10) received midazolam, 0.3 mg/kg. Baroreflex function was assesse...

journal_title：Anesthesia and analgesia

authors： Marty J,Gauzit R,Lefevre P,Couderc E,Farinotti R,Henzel C,Desmonts JM

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:It remains unknown whether continuous or scheduled intermittent bolus local anesthetic administration is preferable for transversus abdominis plane (TAP) catheters. We therefore tested the hypothesis that when using TAP catheters, providing local anesthetic in repeated bolus doses increases the cephalad-caud...

journal_title：Anesthesia and analgesia

authors： Khatibi B,Said ET,Sztain JF,Monahan AM,Gabriel RA,Furnish TJ,Tran JT,Donohue MC,Ilfeld BM

更新日期：2017-04-01 00:00:00

abstract：:A combination of pancuronium and d-tubocurarine is associated with potentiation of the neuromuscular blocking effects of each drug used singly. The time to onset of maximum block and the time to 25% recovery after administration of equipotent (ED95) doses of pancuronium (0.07 mg/kg) alone, d-tubocurarine (0.51 mg/kg) ...

journal_title：Anesthesia and analgesia

authors： Mirakhur RK,Pandit SK,Ferres CJ,Gibson FM

更新日期：1984-04-01 00:00:00

abstract：:The effects of continuous epidural anesthesia and of general anesthesia on the incidence of thromboembolism following total hip replacement were studied. Sixty patients were randomly allotted to one of two groups receiving either epidural or general anesthesia. Epidural anesthesia (N = 30) consisted of 0.5% bupivacain...

journal_title：Anesthesia and analgesia

authors： Modig J,Borg T,Karlström G,Maripuu E,Sahlstedt B

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:N-methyl-D-aspartate receptor (NMDARs)-dependent central sensitization plays an important role in cancer pain. Binding of NMDAR subunit 2B (NR2B) by postsynaptic density protein-95 (PSD-95) can couple NMDAR activity to intracellular enzymes, such as neuronal nitric oxide synthase (nNOS), facilitate downstrea...

journal_title：Anesthesia and analgesia

authors： Liu Y,Cui X,Sun YE,Yang X,Ni K,Zhou Y,Ma Z,Gu X

更新日期：2014-06-01 00:00:00

abstract：:Anecdotal reports suggest that soda lime and Baralyme brand absorbent can degrade inhaled anesthetics to carbon monoxide (CO). We examined the factors that govern CO production and found that these include: 1) The anesthetic used: for a given minimum alveolar anesthetic concentration (MAC)-multiple, the magnitude of C...

journal_title：Anesthesia and analgesia

authors： Fang ZX,Eger EI 2nd,Laster MJ,Chortkoff BS,Kandel L,Ionescu P

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Hypotension after spinal anesthesia for cesarean delivery is common. Previous studies have demonstrated that a crystalloid fluid "coload" (rapid administration of a fluid bolus starting at the time of intrathecal injection) is superior to the conventional crystalloid preload (fluid administered before the in...

journal_title：Anesthesia and analgesia

authors： Siddik-Sayyid SM,Nasr VG,Taha SK,Zbeide RA,Shehade JM,Al Alami AA,Mokadem FH,Abdallah FW,Baraka AS,Aouad MT

更新日期：2009-10-01 00:00:00

abstract：UNLABELLED:Patients may have concerns about their ability to manage postoperative symptoms at home after ambulatory surgery. We assessed patients' attitudes toward postoperative care at home or in the hospital after laparoscopic cholecystectomy. Thirty-eight patients undergoing elective laparoscopic cholecystectomy wer...

journal_title：Anesthesia and analgesia

authors： Lehmann HP,Fleisher LA,Lam J,Frink BA,Bass EB

更新日期：1999-06-01 00:00:00

abstract：:Activity of methionine synthetase was measured in liver biopsies of seven patients who had received 50% to 70% nitrous oxide supplemented by a combination of a narcotic and/or barbiturate with or without a volatile anesthetic, and from seven patients who were anesthetized without nitrous oxide (control group). Methion...

journal_title：Anesthesia and analgesia

authors： Koblin DD,Waskell L,Watson JE,Stokstad EL,Eger EI 2nd

更新日期：1982-02-01 00:00:00

abstract：:We investigated the usefulness of peripheral flow index (PFI) measurement using a standard pulse oximetry digit probe for early prediction of successful regional blocks. Sixty-six patients scheduled for limb surgery underwent either axillary or sciatic block using a nerve stimulator technique with mepivacaine 1.5%. PF...

journal_title：Anesthesia and analgesia

authors： Galvin EM,Niehof S,Verbrugge SJ,Maissan I,Jahn A,Klein J,van Bommel J

更新日期：2006-07-01 00:00:00

abstract：:Windup is a progressive increase in responses of nociceptive spinal cord neurons to repeated electrical C fiber stimulation. We hypothesized that isoflurane would depress windup at approximately the minimum alveolar anesthetic concentration (MAC) required to suppress purposeful movement in response to noxious stimulat...

journal_title：Anesthesia and analgesia

authors： Jinks SL,Antognini JF,Dutton RC,Carstens E,Eger EI 2nd

更新日期：2004-11-01 00:00:00

abstract：:In this study, we assessed the relationship between brain estimated specific gravity (eSG) and clinical symptoms, therapeutic intensity level, and outcome in human traumatic brain injury (TBI). Brain weight, volume, and eSG of the noncontused hemispheric areas were measured from computed tomography (CT) DICOM images o...

journal_title：Anesthesia and analgesia

authors： Degos V,Lescot T,Zouaoui A,Hermann H,Préteux F,Coriat P,Puybasset L

更新日期：2006-11-01 00:00:00

abstract：:Carbon dioxide insufflation during laparoscopic surgery may interfere with the accuracy of the cardiac output value measured by the NICO2 system. The authors simultaneously measured cardiac output by the thermodilution method and by the carbon dioxide rebreathing technique during laparoscopic adrenalectomy in a patien...

journal_title：Anesthesia and analgesia

authors： Suzuki M,Koda S,Nakamura Y,Kawamura N,Shimada Y

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The electroencephalogram (EEG) measures cerebral activity and, because of its use as an intraoperative monitor, the Accreditation Council for Graduate Medical Education requires EEG monitoring experience during anesthesiology residency. To improve the anesthesiology residents' education at the University of ...

journal_title：Anesthesia and analgesia

authors： Fahy BG,Chau DF,Owen MB

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Multiple interventions have been tested in models of cardiopulmonary resuscitation (CPR) to optimize drug use, chest compressions, and ventilation. None has studied the effects of positive end-expiratory pressure (PEEP) on outcome. We hypothesized that because PEEP can reverse pulmonary atelectasis, lower pu...

journal_title：Anesthesia and analgesia

authors： McCaul C,Kornecki A,Engelberts D,McNamara P,Kavanagh BP

更新日期：2009-10-01 00:00:00

abstract：:The tandem pore domain K channel family mediates background K currents present in excitable cells. Currents passed by certain members of the family are enhanced by volatile anesthetics, thus suggesting a novel mechanism of anesthesia. The newest member of the family, termed TRESK (TWIK [tandem pore domain weak inward ...

journal_title：Anesthesia and analgesia

authors： Liu C,Au JD,Zou HL,Cotten JF,Yost CS

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The inflated costs and documented deleterious effects of excess perioperative transfusion have led to the investigation of targeted coagulation factor replacement strategies. One particular coagulation factor of interest is factor I (fibrinogen). Hypofibrinogenemia is typically tested for using time-consumin...

journal_title：Anesthesia and analgesia

authors： Fabbro M 2nd,Gutsche JT,Miano TA,Augoustides JG,Patel PA

更新日期：2016-09-01 00:00:00

abstract：UNLABELLED:To evaluate the influence of needle type on the lateral distribution of 0.5% hyperbaric bupivacaine, 30 patients undergoing lower limb surgery were placed in the lateral position with the side to be operated on dependent and underwent dural puncture by either a 25-gauge Whitacre (n = 15) or a 25-gauge Quinck...

journal_title：Anesthesia and analgesia

authors： Casati A,Fanelli G,Cappelleri G,Aldegheri G,Leoni A,Casaletti E,Torri G

更新日期：1998-08-01 00:00:00

abstract：:The anesthetic effect of lidocaine was evaluated in rats by determining the change in anesthetic requirement of cyclopropane MAC that was produced by blood concentrations of lidocaine in the clinically useful range. A linear reduction in anesthetic requirement was produced with concentrations up to 1 mug/ml. Further i...

journal_title：Anesthesia and analgesia

authors： DiFazio CA,Neiderlehner JR,Burney RG

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:In this study, we evaluated the feasibility and accuracy of Univent tube (Fuji Systems, Tokyo, Japan) placement with the aid of auscultation (AUS) or as guided by a lighted stylet (LS) compared with placement guided by the fiberoptic bronchoscope (FOB) or the blind intubation technique as recommended by the ...

journal_title：Anesthesia and analgesia

authors： Weng H,Xu ZY,Liu J,Ma D,Liu DS

更新日期：2010-02-01 00:00:00

abstract：:After it was learned that electroanesthesia (EA) could not be produced in a Rhesus monkey which had undergone a circumferential scalp block with 0.25% lidocaine, it was postulated that EA could be produced by electrostimulation of the sensory nerves of the scalp in the rhesus. The work reported here verifies that EA c...

journal_title：Anesthesia and analgesia

authors： Kano T,Cowan GS,Smith RH

更新日期：1976-07-01 00:00:00

abstract：:Postoperative sensitivity to tactile stimuli differs as a function of age. In this study, we hypothesized that preoperative sciatic nerve block (SNB), by providing preemptive analgesia, would result in better analgesia than postoperative SNB in the young rat. With the paw incision model of postoperative pain, male Spr...

journal_title：Anesthesia and analgesia

authors： Ririe DG,Barclay D,Prout H,Tong C,Tobin JR,Eisenach JC

更新日期：2004-07-01 00:00:00

abstract：:The Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research, established by the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks public-private partnership with the US Food and Drug Administration, convened a meeting of sedation e...

journal_title：Anesthesia and analgesia

authors： Williams MR,Ward DS,Carlson D,Cravero J,Dexter F,Lightdale JR,Mason KP,Miner J,Vargo JJ,Berkenbosch JW,Clark RM,Constant I,Dionne R,Dworkin RH,Gozal D,Grayzel D,Irwin MG,Lerman J,O'Connor RE,Pandharipande P,Rappap

更新日期：2017-03-01 00:00:00

abstract：:Three-centimetre linear incisions were made in 90 young male Lew/f Mai rats by scalpel through skin to the investing fascia of the left flank. The skin was undermined sharply for a distance of 0.5 cm along both sides of the entire length of the incision. The wound site was closed per primam with Michel clips and left ...

journal_title：Anesthesia and analgesia

authors： Shah NK,Kripke BJ,Sanzone CF,Cosman EB

更新日期：1978-09-01 00:00:00