Effects of diazepam and midazolam on baroreflex control of heart rate and on sympathetic activity in humans.

abstract：UNLABELLED:Numerous clinical studies suggest that methylprednisolone may facilitate early tracheal extubation after cardiac surgery, yet no investigation has rigorously examined the use of the drug in this setting. In this prospective, randomized, double-blind, placebo-controlled study, we examined the pulmonary effect...

journal_title：Anesthesia and analgesia

authors： Chaney MA,Nikolov MP,Blakeman B,Bakhos M,Slogoff S

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Acute lung injury is a recognized complication of lower limb ischemia-reperfusion that has been demonstrated experimentally and in the clinical setting of aortic surgery. The application of a tourniquet can cause lower limb ischemia-reperfusion in orthopedic surgery. We studied the effect of unilateral thigh...

journal_title：Anesthesia and analgesia

authors： Lin LN,Wang LR,Wang WT,Jin LL,Zhao XY,Zheng LP,Jin LD,Jiang LM,Xiong XQ

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Early hyperglycemia is associated with multiple organ failure (MOF) after traumatic injury; however, few studies have considered the contribution of depth of clinical shock. We hypothesize that when considered simultaneously, glucose and lactate are associated with MOF in severely injured blunt trauma patien...

journal_title：Anesthesia and analgesia

authors： Richards JE,Scalea TM,Mazzeffi MA,Rock P,Galvagno SM Jr

更新日期：2018-03-01 00:00:00

abstract：:The hypnotic effects of propofol, midazolam, alfentanil, and their binary and triple combinations, were studied in 130 unpremedicated patients in a randomized, double-blind fashion. The ability to open eyes on verbal command was used as an end-point. Dose-response curves for the three drugs given separately and in com...

journal_title：Anesthesia and analgesia

authors： Vinik HR,Bradley EL Jr,Kissin I

更新日期：1994-02-01 00:00:00

abstract：UNLABELLED:We assessed the sedative potential of continuous infusions of remifentanil with a validated composite alertness scale in 160 patients (ASA physical status I or II) undergoing hip replacement surgery with spinal block (n = 61) or hand surgery using brachial plexus block (n = 93). They were randomized to recei...

journal_title：Anesthesia and analgesia

authors： Lauwers M,Camu F,Breivik H,Hagelberg A,Rosen M,Sneyd R,Horn A,Noronha D,Shaikh S

更新日期：1999-01-01 00:00:00

abstract：:The purpose of this study was to measure cardiac sympathetic nerve activity (CSNA) and atrioventricular (AV) conduction and to test the effects of dobutamine (DOB) and phenylephrine (PHE) on AV conduction during combined use of halothane and thoracic epidural lidocaine. Cats were anesthetized with 1 % halothane and an...

journal_title：Anesthesia and analgesia

authors： Nishikawa K,Yabe M,Mori T,Terai T,Yukioka H,Fujimori M

更新日期：1996-03-01 00:00:00

abstract：UNLABELLED:We performed this study to assess the safety of immediate extubation after elective abdominal aortic aneurysm surgery. Consecutive patients were prospectively randomized into two groups after surgery: Group 1 (n = 29) immediate extubation; and Group 2 (n = 21) delayed (at least 4 h) extubation. All patients ...

journal_title：Anesthesia and analgesia

authors： Cohen J,Loewinger J,Hutin K,Sulkes J,Zelikovski A,Singer P

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Various different interventions can be used to reduce surgical blood loss; however, there is no "gold standard" for accurately measuring the volume of perioperative blood loss, and this makes it difficult to assess the efficacy of these interventions. METHODS:We used data from a previous multicenter double-...

journal_title：Anesthesia and analgesia

authors： Lopez-Picado A,Albinarrate A,Barrachina B

更新日期：2017-07-01 00:00:00

abstract：UNLABELLED:We selected bis [N-(3,4-diacetoxybenzyl) tropanium-3alpha-yl] glutarate dibromide (TAAC3) from many new tropinyl diester derivatives to evaluate its neuromuscular blocking (NMB) and autonomic side effects on anesthetized rats, rabbits, guinea pigs, cats, pigs, dogs, and monkeys. NMB potency, onset, recovery ...

journal_title：Anesthesia and analgesia

authors： Gyermek L,Lee C,Cho YM,Nguyen N,Tsai SK

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Pulse oximetry-derived oxygen saturation is typically >97% in normoxia and hyperoxia, limiting its clinical use. The new Oxygen Reserve Index (ORi), a relative indicator of the partial pressure of oxygen dissolved in arterial blood (PaO2) in the range of 100-200 mm Hg, may allow additional monitoring of oxyg...

journal_title：Anesthesia and analgesia

authors： Vos JJ,Willems CH,van Amsterdam K,van den Berg JP,Spanjersberg R,Struys MMRF,Scheeren TWL

更新日期：2019-08-01 00:00:00

abstract：:Many in vitro effects of volatile anesthetics are known, but the mechanisms of action are still under debate. Because suppression of sensory perception is one of the major goals of general anesthesia, we studied the effects of isoflurane on the processing of somatosensory information in anesthetized rats. Local iontop...

journal_title：Anesthesia and analgesia

authors： Vahle-Hinz C,Detsch O,Siemers M,Kochs E,Bromm B

更新日期：2001-06-01 00:00:00

abstract：:We studied the pharmacokinetics of thiopental enantiomers in 14 healthy patients aged 37-73 yr receiving racemic thiopental by intravenous (IV) bolus or IV infusion. Plasma concentration of each enantiomer was measured by chiral high-performance liquid chromatography. After IV bolus, the total plasma clearance (CL) (2...

journal_title：Anesthesia and analgesia

authors： Nguyen KT,Stephens DP,McLeish MJ,Crankshaw DP,Morgan DJ

更新日期：1996-09-01 00:00:00

abstract：:The alpha 2-adrenergic receptor agonist dexmedetomidine produces an anesthetic state in a variety of species. Although its effects on cerebral blood flow and the electroencephalogram have been investigated, the effect of this drug on intracranial pressure (ICP) has not been reported previously. Dexmedetomidine therefo...

journal_title：Anesthesia and analgesia

authors： Zornow MH,Scheller MS,Sheehan PB,Strnat MA,Matsumoto M

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:The accurate measurement of oxygen consumption (VO2) and energy expenditure (EE) may be helpful to optimize the treatment of critically ill patients. However, current techniques are limited in their ability to accurately quantify these end points in infants due to a low VO2, low tidal volume, and rapid respi...

journal_title：Anesthesia and analgesia

authors： Nachman E,Clemensen P,Santos K,Cole AR,Polizzotti BD,Hofmann G,Leeman KT,van den Bosch SJ,Kheir JN

更新日期：2018-07-01 00:00:00

abstract：:A recognized side effect of chemonucleolysis is life-threatening anaphylaxis to chymopapain. In the clinical trials of chymopapain, 13 cases of anaphylaxis were reported in 1585 administrations (0.82%). Two patients died. Data from a postmarketing survey (48,239 questionnaires) were reviewed to identify factors influe...

journal_title：Anesthesia and analgesia

authors： Moss J,Roizen MF,Nordby EJ,Thisted R,Apfelbaum JL,Schreider BD,McDermott DJ

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Severe exacerbation of chronic neuropathic pain often requires morphine in patients already treated with drugs such as tricyclic antidepressants, carbamazepine and gabapentin. However, it is unclear if a combination of these drugs intensifies the effects of morphine on the respiratory system and, if so, whet...

journal_title：Anesthesia and analgesia

authors： Kozer E,Levichek Z,Hoshino N,Kapur B,Leombruno J,Taguchi N,Garcia-Bournissen F,Koren G,Ito S

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Near-infrared spectroscopy is used during cardiac surgery to monitor the adequacy of cerebral perfusion. In this systematic review, we evaluated available data for adult patients to determine (1) whether decrements in cerebral oximetry during cardiac surgery are associated with stroke, postoperative cognitiv...

journal_title：Anesthesia and analgesia

authors： Zheng F,Sheinberg R,Yee MS,Ono M,Zheng Y,Hogue CW

更新日期：2013-03-01 00:00:00

abstract：:Acid-base status and blood levels of bupivacaine were determined in 16 diabetic parturients and their infants after epidural anesthesia for cesarean section. The newborn infants were divided into two groups based on umbilical artery pH at birth. Group A consisted of 10 infants who had a pH of less than 7.2 and group B...

journal_title：Anesthesia and analgesia

authors： Datta S,Brown WU Jr,Ostheimer GW,Weiss JB,Alper MH

更新日期：1981-08-01 00:00:00

abstract：:The direct effect of protamine sulfate upon myocardial inotropism was studied using an isolated canine heart muscle preparation. Isometric force (F) was decreased to 87.6 +/- 1.2% of control values by a concentration of 50 x 10(-3) g/L protamine, which is approximately equal to the estimated serum concentration of pro...

journal_title：Anesthesia and analgesia

authors： Iwatsuki N,Matsukawa S,Iwatsuki K

更新日期：1980-02-01 00:00:00

abstract：UNLABELLED:IV volume is often administered to patients in an intensive care unit (ICU) to improve cardiovascular function. We investigated the relationship between stroke volume (SV) and left ventricular (LV) size by using transesophageal echocardiography (TEE) in a population of 20 ICU patients and 21 postoperative ca...

journal_title：Anesthesia and analgesia

authors： Tousignant CP,Walsh F,Mazer CD

更新日期：2000-02-01 00:00:00

abstract：:Experimental aspiration pneumonitis studies in general have focused on the pathogenesis of the acidic component of the lung injury, although the injury produced by the particulate component of gastric contents largely has been ignored. The present study compares the inflammatory potential of small gastric particles to...

journal_title：Anesthesia and analgesia

authors： Knight PR,Rutter T,Tait AR,Coleman E,Johnson K

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:In the present study, we examined the effects and mechanisms of the Chinese herb resveratrol on attenuation of morphine tolerance in rats. METHODS:Male Wistar rats were implanted with 2 intrathecal catheters; one catheter was connected to a mini-osmotic pump, used for either morphine (15 μg/h) or saline (1 ...

journal_title：Anesthesia and analgesia

authors： Tsai RY,Chou KY,Shen CH,Chien CC,Tsai WY,Huang YN,Tao PL,Lin YS,Wong CS

更新日期：2012-10-01 00:00:00

abstract：UNLABELLED:The enhancing action of propofol on gamma-amino-n-butyric acid subtype A (GABA(A)) receptors purportedly underlies its anesthetic effects. However, a recent study found that a GABA(A) antagonist did not alter the capacity of propofol to depress the righting reflex. We examined whether the noncompetitive GABA...

journal_title：Anesthesia and analgesia

authors： Sonner JM,Zhang Y,Stabernack C,Abaigar W,Xing Y,Laster MJ

更新日期：2003-03-01 00:00:00

abstract：:A 7-year-old girl manifested the rare anomaly of a ventricular septal defect (VSD) with left aortic arch, right descending aorta, and right ligamentum arteriosum. After open-heart surgery to correct the VSD, symptoms of tracheal obstruction on spontaneous breathing developed, due to tracheal compression by the right l...

journal_title：Anesthesia and analgesia

authors： Moorthy SS,Franken EA,LoSasso AM,King H

更新日期：1976-07-01 00:00:00

abstract：:Over the last decade, there has been a heightened awareness and an increase in the amount of literature being published on recognition and prediction of the difficult airway. During the preoperative evaluation of the airway, a thorough history and physical specifically related to the airway should be performed. Variou...

journal_title：Anesthesia and analgesia

authors： Cattano D,Panicucci E,Paolicchi A,Forfori F,Giunta F,Hagberg C

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Recent attention to adverse effects of intensive care unit (ICU) sedation has led to the use of strategies that target a "lighter" depth of sedation. Among these strategies are "analgosedation" protocols, which prioritize pain management and preferentially use IV opioids before administration of continuously...

journal_title：Anesthesia and analgesia

authors： Faust AC,Rajan P,Sheperd LA,Alvarez CA,McCorstin P,Doebele RL

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Performing key actions efficiently during crises can determine clinical outcomes, yet even expert clinicians omit key actions. Simulation-based studies of crises show that correct performance of key actions dramatically increases when emergency manuals (EMs) are used. Despite widespread dissemination of EMs,...

journal_title：Anesthesia and analgesia

authors： Goldhaber-Fiebert SN,Bereknyei Merrell S,Agarwala AV,De La Cruz MM,Cooper JB,Howard SK,Asch SM,Gaba DM

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Although bone cancer-related pain is one of the most disruptive symptoms in patients with advanced cancer, patients are often refractory to pharmacological treatments; thus, more effective treatments for bone cancer pain are needed. We evaluated the analgesic efficacy of and interaction between intrathecal G...

journal_title：Anesthesia and analgesia

authors： Kim WM,Jeong CW,Lee SH,Kim YO,Cui JH,Yoon MH

更新日期：2011-10-01 00:00:00

abstract：:Our goal in this study was to develop a robotic intubation system and to conduct a feasibility pilot study on the use of a robotic intubation system for endotracheal intubations. The Kepler Intubation System was developed, consisting of a remote control center (joystick and intubation cockpit) linked to a standard vid...

journal_title：Anesthesia and analgesia

authors： Hemmerling TM,Wehbe M,Zaouter C,Taddei R,Morse J

更新日期：2012-03-01 00:00:00

abstract：UNLABELLED:Several pharmacological interventions reduce perioperative stress hormone release during surgery under general anesthesia. Listening to music and therapeutic suggestions were also studied, but mostly in awake patients, and these have a positive effect on postoperative recovery and the need for analgesia. In ...

journal_title：Anesthesia and analgesia

authors： Migneault B,Girard F,Albert C,Chouinard P,Boudreault D,Provencher D,Todorov A,Ruel M,Girard DC

更新日期：2004-02-01 00:00:00