Abstract:
OBJECTIVE:In this prospective, observational study, we determined whether serum C-reactive protein (CRP) correlated with necrotizing enterocolitis (NEC) stages II and III. We hypothesized that serial CRP measurement if used as an adjunct to abdominal radiographs would improve the identification of infants with NEC. METHODS:Serum CRP level was measured every 12 hours for 3 measurements and, when abnormal, once daily. When clinical signs persisted and the initial abdominal radiographs were abnormal, follow-up radiographs were obtained. RESULTS:Of 241 infants who were evaluated for gastrointestinal signs, 11 had ileus or benign pneumatosis intestinalis with persistently normal CRP; gastrointestinal manifestations resolved within 48 hours, antibiotics were discontinued in <48 hours, and feedings were restarted early without complications. Fifty-five infants had NEC stages II and III; all had abnormal CRP regardless of their blood culture results. In infants with stage II NEC, CRP returned to normal at a mean of 9 days except in those who developed complications such as stricture or abscess formation. CONCLUSIONS:In infants with suspected NEC, normal serial CRP values would favor aborted antibiotic therapy and early resumption of feedings. CRP becomes abnormal in both stage II and stage III NEC. In infants with NEC, persistently elevated CRP after initiation of appropriate medical management suggests associated complications, which may require surgical intervention.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Pourcyrous M,Korones SB,Yang W,Boulden TF,Bada HSdoi
10.1542/peds.2004-1806subject
Has Abstractpub_date
2005-11-01 00:00:00pages
1064-9issue
5eissn
0031-4005issn
1098-4275pii
116/5/1064journal_volume
116pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract:OBJECTIVES:Recent analyses assessing the impact of the conjugate pneumococcal vaccine on the care of febrile children do not reflect the role parental preferences play in physicians' decisions. The objective of this study was to identify the management strategy that would best suit parents, on the basis of their values...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-1865
更新日期:2006-04-01 00:00:00
abstract::Pediatric care providers, pediatricians, pediatric subspecialty physicians, and other health care providers should be able to recognize children with abnormal head shapes that occur as a result of both synostotic and deformational processes. The purpose of this clinical report is to review the characteristic head shap...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2020-015511
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVES:The prevalence and identification of hypertriglyceridemia in youths will likely will increase in the future as a consequence of childhood obesity and increased screening for dyslipidemias. We sought to review our clinical experience with hypertriglyceridemia, evaluate factors associated with increased trigly...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-0367
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVES:To characterize the epidemiology of genital human papillomavirus (HPV) infection in children without previous consensual sexual activity, comparing HPV prevalence by certainty of child sexual abuse (CSA). PATIENTS AND METHODS:Patients presenting for evaluation of CSA in 8 sites in Atlanta, Houston, Harrisbu...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2010-2247
更新日期:2011-09-01 00:00:00
abstract::The following is the winning submission from the Fourth Annual Section on Pediatric Trainees Essay Competition. This year's competition was informed by the 2019-2020 Section on Pediatric Trainees Advocacy Campaign: Protect Kids - Trainees for Firearm Safety. We asked writers to share their experiences as pediatric tra...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2020-015974
更新日期:2020-10-01 00:00:00
abstract::There is an increasing threat that chemical and biological weapons will be used on a civilian population in an act of domestic terrorism. Casualties among adults and children could be significant in such an event. Federal, state, and local authorities have begun extensive planning to meet a chemical-biological inciden...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.105.3.662
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVE:We investigated whether the duration and exclusivity of breastfeeding affects the likelihood of gross and fine motor delay in infants and examined the effect of factors that might explain any observed differences. METHODS:The study sample included all term singleton infants who weighed > 2500 g at birth and ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-3141
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVES:Clinical evidence indicates newborn critical congenital heart disease (CCHD) screening through pulse oximetry is lifesaving. In 2011, CCHD was added to the US Recommended Uniform Screening Panel for newborns. Several states have implemented or are considering screening mandates. This study aimed to estimate ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-0332
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:As rates of neonatal opioid withdrawal are increasing, the need for research to evaluate new treatments is growing. Large heterogeneity exists in health outcomes reported in current literature. Our objective is to develop an evidence-informed and consensus-based core outcome set in neonatal opioid withdrawal...
journal_title:Pediatrics
pub_type: 共识发展会议,杂志文章
doi:10.1542/peds.2020-0018
更新日期:2020-07-01 00:00:00
abstract::Streptococcus pneumoniae-associated hemolytic uremic syndrome (HUS) is an underrecognized condition that mainly occurs in young children. Early diagnosis is important because of the potential to improve morbidity and mortality rates. The purposes of this report are to review the clinical and laboratory features of 14 ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2007-2017
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:Allergic rhinitis is common and on the rise. Antihistamines are the mainstay of treatment and are the most commonly prescribed drugs in Singapore. Treatment-related sedation and its effect on cognition are a major concern. First- and second-generation antihistamines show varying degrees of sedation, but to da...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1542/peds.113.2.e116
更新日期:2004-02-01 00:00:00
abstract::Diskitis, an inflammation of the intervertebral disk, is generally attributable to Staphylococcus aureus and rarely Staphylococcus epidermidis, Kingella kingae, Enterobacteriaciae, and Streptococcus pneumoniae. In many cases, no bacterial growth is obtained from infected intervertebral discs. Although anaerobic bacter...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.107.2.e26
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:Advances in medical care have led to a growing population of special needs children who are at risk for suboptimal care when they present to a physician with no previous knowledge of their medical history. This risk may be amplified in the emergency department setting when time-sensitive interventions must be...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.102.2.367
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVE:In this study we sought to evaluate the efficacy of motivational interviewing (MI) compared with structured brief advice (SBA) for adolescent smoking behavior change. METHODS:Participants (N=355) were randomly assigned to 5 sessions of either MI or SBA. The primary outcomes were attempts to reduce and to qui...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2010-2174
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:Although invasive pneumococcal disease is infrequent in cystic fibrosis (CF), it is recommended that all patients with CF receive pneumococcal immunization. As part of a comprehensive program to immunize our clinic population, we obtained preimmunization anti-pneumococcal antibody levels. We hypothesized that...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.108.4.e62
更新日期:2001-10-01 00:00:00
abstract:OBJECTIVES:To describe normative sexual behavior in Dutch-speaking children; to assess the frequencies of different types of sexual behaviors reported in children by their parents; to analyze the relation of these sexual behaviors to demographic, personal, familial, and general behavioral variables; and to compare the ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.104.4.885
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:"Ampicillin rash," a phenomenon unique to patients with Epstein-Barr virus acute infectious mononucleosis (AIM) treated with ampicillin, was first reported in the 1960s. The incidence was estimated as being between 80% and 100%, and the figures have not been reviewed since those first accounts. We sought to ...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2012-1575
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of pacifier use and whether this habit adversely affects the health of 6-month-old infants. DESIGN:Data collected via self-completion questionnaires from mothers forming part of the prospective, population-based Avon Longitudinal Study of Pregnancy and Childhood. METHODS:The mothers...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.103.3.e34
更新日期:1999-03-01 00:00:00
abstract::We reviewed randomized trials of prenatal and infancy home-visitation programs for socially disadvantaged women and children. Some home-visitation programs were effective in improving women's health-related behaviors during pregnancy, the birth weight and length of gestation of babies born to smokers and young adolesc...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:1990-07-01 00:00:00
abstract::Since the American Heart Association last presented nutrition guidelines for children, significant changes have occurred in the prevalence of cardiovascular risk factors and nutrition behaviors in children. Overweight has increased, whereas saturated fat and cholesterol intake have decreased, at least as percentage of...
journal_title:Pediatrics
pub_type: 杂志文章,实务指引
doi:10.1542/peds.2005-2374
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:To mitigate the risks of fatigue-related medical errors, the Accreditation Council for Graduate Medical Education introduced work hour limits for resident physicians in 2003. Our goal was to determine whether work hours, sleep, and safety changed after implementation of the Accreditation Council for Graduate ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2007-2306
更新日期:2008-08-01 00:00:00
abstract::Services for children with special needs in England and Wales are described briefly, with attention to the services provided by the National Health Service, local authorities, the social security system, and voluntary organizations. For illustrative purposes, particular reference is made to children with hearing impai...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-12-01 00:00:00
abstract::In 1992, the Committee on Infectious Diseases and Committee on Fetus and Newborn of the American Academy of Pediatrics provided guidelines for prevention of early-onset group B streptococcal (GBS) disease through intrapartum chemoprophylaxis of selected maternal GBS carriers. The guidelines were based on demonstrated ...
journal_title:Pediatrics
pub_type: 指南,杂志文章,实务指引
doi:10.1542/peds.99.3.489
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:An increase in the incidence of systemic candidiasis (SC) followed a change in skin care for extremely low birth weight (ELBW) infants in our neonatal intensive care unit (NICU). We sought to determine whether the use of topical petrolatum ointment (TPO) for skin care of ELBW infants was associ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.105.5.1041
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:Although the Centers for Disease Control (CDC) growth charts are widely used in studies of childhood obesity, BMI z scores are known to be inaccurate at values greater than the 97th percentile. METHODS:We used longitudinal data from 6994 children in the Bogalusa Heart Study who were examined multiple times ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-1072
更新日期:2017-09-01 00:00:00
abstract::Immunodeficiency-centromeric instability-facial dysmorphism syndrome, characterized by variable immunodeficiency, centromeric instability, and facial anomalies caused by epigenetic dysregulation resulting in hypomethylation, is caused in many patients by mutations in DNMT3B, a DNA methyltransferase gene; associated in...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2007-0640
更新日期:2007-11-01 00:00:00
abstract::Investigations in which statistically significant differences between treatment groups have not been observed are less likely than others to be reported in scientific journals. In clinical research, this selective suppression of "negative" results may lead to the adoption of ineffective or hazardous treatments. In an ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-08-01 00:00:00
abstract:OBJECTIVE:Disseminated bacillus Calmette-Guérin (BCG) infection after inoculation of live vaccine is considered to result from impaired immunity of the child. However, in half of the cases, regarded as idiopathic, no well-defined immunodeficiency condition can account for the infection. The objective of the present stu...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::A 4-year-old Jewish boy presented with dysuria, urinary dribbling, increased urinary frequency, and new onset of diurnal enuresis. An infiltrating solid mass involving the entire bladder wall was found. Biopsy revealed "tumor-forming" eosinophilic cystitis, a rare bladder lesion of unclear cause. Antitoxocariasis trea...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.108.6.e113
更新日期:2001-12-01 00:00:00
abstract::Echocardiographic evaluation of left ventricular (LV) performance was performed in 41 children during and following anthracycline chemotherapy. Prior to treatment LV function was normal in all patients; LV shortening fraction was 35.2 +/- 0.7% and percent of predicted velocity of circumferential fiber shortening was 1...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1981-07-01 00:00:00