Abstract：
:This study compared color appearance data for two populations of middle-aged women: (1) women using the selective estrogen receptor modulator tamoxifen as adjuvant therapy following successful treatment for early-stage breast cancer, and (2) healthy amenorrheic (peri- or post-menopausal) control subjects not using any hormonally acting medications. A 3-alternative forced-response paradigm (with "blue", "lavender", or "white" as the allowable responses) was used for assessing the perceived color of 440-nm foveal test stimuli superimposed on a larger 3.6 log td 580-nm background. In contrast to the control subjects, the majority of tamoxifen users described the test stimuli as "white", whether at threshold or slightly suprathreshold. Threshold-sensitivity measurements themselves appeared less effective for distinguishing between subject groups. The results show that a simple color-naming procedure can reveal alterations of foveal short-wavelength-sensitive cone-mediated visual function that are common among tamoxifen users.
journal_name
Vision Resjournal_title
Vision researchauthors
Eisner A,Incognito LJdoi
10.1016/j.visres.2005.11.003subject
Has Abstractpub_date
2006-05-01 00:00:00pages
1816-22issue
11eissn
0042-6989issn
1878-5646pii
S0042-6989(05)00562-6journal_volume
46pub_type
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