Abstract:
:Effects of glutamate and its agonists on horizontal cells appeared diversely when studied in turtle eyecup preparations. Consistent results were obtained when the isolated retina preparations were used. Not only kainate and quisqualate but also N-methyl-D-aspartate (NMDA) caused a sustained depolarization and light-evoked responses were suppressed for as long as these agonists were superfused. A selective antagonist of NMDA, 2-amino-5-phosphonovalerate (APV), hyperpolarized horizontal cells and reduced their light-evoked responses. These results indicate the coexistence of NMDA and non-NMDA receptors on turtle horizontal cells.
journal_name
Vision Resjournal_title
Vision researchauthors
Miyachi E,Murakami Mdoi
10.1016/0042-6989(89)90002-3subject
Has Abstractpub_date
1989-01-01 00:00:00pages
385-8issue
4eissn
0042-6989issn
1878-5646pii
0042-6989(89)90002-3journal_volume
29pub_type
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