Coexistence of NMDA and non-NMDA receptors on turtle horizontal cells revealed using isolated retina preparations.

Abstract:

:Effects of glutamate and its agonists on horizontal cells appeared diversely when studied in turtle eyecup preparations. Consistent results were obtained when the isolated retina preparations were used. Not only kainate and quisqualate but also N-methyl-D-aspartate (NMDA) caused a sustained depolarization and light-evoked responses were suppressed for as long as these agonists were superfused. A selective antagonist of NMDA, 2-amino-5-phosphonovalerate (APV), hyperpolarized horizontal cells and reduced their light-evoked responses. These results indicate the coexistence of NMDA and non-NMDA receptors on turtle horizontal cells.

journal_name

Vision Res

journal_title

Vision research

authors

Miyachi E,Murakami M

doi

10.1016/0042-6989(89)90002-3

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

385-8

issue

4

eissn

0042-6989

issn

1878-5646

pii

0042-6989(89)90002-3

journal_volume

29

pub_type

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