Abstract:
:Due to their infrequency and multiplicity of histopathology, myoepitheliomas present difficulties in diagnosis and classification. Cellular varieties can be misdiagnosed as malignancies. Improvements in and clarification of diagnostic criteria are, therefore, required. A key to determining diagnostic criteria for myoepitheliomas is to study cellular morphology, cytoplasmic filament expression, and ultrastructural features of the nonluminal, i.e., neoplastic myoepithelial/basal, tumor cells of pleomorphic adenomas, and apply this information to defining myoepitheliomas. Cytologic and growth patterns of nonluminal cells in pleomorphic adenomas, including plasma-cytoid cells, are reflected in myoepitheliomas. Results also indicate that muscle-specific actin and myofilaments are expressed only in a proportion of cases, and generally in not more than 60-70% of nonluminal cells in pleomorphic adenoma; this also applies to benign and malignant myoepitheliomas. The absence of these markers does not exclude a diagnosis of myoepithelioma. Vimentin and glial acidic fibrillary protein, however, are strongly and diffusely expressed in the majority of pleomorphic adenomas and myoepitheliomas and are more reliable markers for these tumors than muscle-specific actin. Like so many other salivary gland tumors, myoepitheliomas present an equally complex histomorphology and variable expression of antigenic markers, only some of which are associated with myoepithelial and basal cells of the acini and ducts of the normal salivary gland.
journal_name
Ultrastruct Patholjournal_title
Ultrastructural pathologyauthors
Dardick Idoi
10.3109/01913129509021906subject
Has Abstractpub_date
1995-09-01 00:00:00pages
335-45issue
5eissn
0191-3123issn
1521-0758journal_volume
19pub_type
杂志文章,评审abstract::A case of lymphoid hyperplasia with prominent plasmacytic proliferation histologically and with polyclonal hypergammaglobulinemia and anemia clinically was reported. This condition in a 54-year-old Japanese male was probably a type of plasma cell dyscrasia similar to a plasma cell variant of Castleman's disease. About...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128409018570
更新日期:1984-01-01 00:00:00
abstract::In an attempt to recognize early stages of focal segmental glomerulosclerosis (FSGS) in patients with a clinical course suggesting a diagnosis other than minimal change disease (MCD) and normal histology, or minor, nondiagnostic changes on light microscopy (LM), we used a protocol for systematic and extensive electron...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128809048472
更新日期:1988-01-01 00:00:00
abstract::Transmission electron microscopy examination of selected diagnostic specimens, that is, renal and nerve biopsies, can be greatly facilitated by the implementation of slot grid preparations that are inherently devoid of any grid bars. Such preparations are conducive to screening and photography at both low and intermed...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128709048459
更新日期:1987-01-01 00:00:00
abstract::By means of optical and electron microscopy and by atomic absorption spectrophotometry in a graphite chamber, this study evaluated the effect of temperature (22-35 degrees C) on lesions in the kidney, liver, and brain, and on concentrations of lead caused by the administration of 2 and 5 mg/kg/IP of lead acetate to Sw...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129609016324
更新日期:1996-05-01 00:00:00
abstract::The study aims to investigate the protective effect of Pimpinella anisum oil on aspartame (ASP) which resulted in cerebellar changes. The rats were divided into four equal groups: Group 1: (control group): served as control animals. Group 2: control P. anisum oil received .5 mL/kg/d/b wt. once daily. Group 3 (ASP grou...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2014.889259
更新日期:2014-05-01 00:00:00
abstract::Adult neuroblastoma is an uncommon tumor and it is rare for one to present as a primary bone lesion. We report the case of a 23-year-old man in whom the tumor initially appeared in the right scapula. Light microscopic, immunocytochemical, and electron microscopic findings were typical of neuroblastoma. ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128709048440
更新日期:1987-01-01 00:00:00
abstract::Elastofibromas have been described as ill-defined tumors, composed of fibroblastic stromal cells and a dense collagenous stroma. A total of 5 elastofibromas from 4 Japanese patients were examined by ultrastructural and immunohistochemical methods. The proliferating fibroblastic stromal cells in the lesion showed Cx43-...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120701350365
更新日期:2007-05-01 00:00:00
abstract::The arginine-rich cationic Tat peptides have been reported to enhance the intracellular delivery of macromolecules, including DNA, RNA, and proteins. In this work an arginine cationic peptide derived from the HIV-1 Tat protein was conjugated with noncovalent bonds to sulfonated aluminum phthalocyanine (AlPcS, a photos...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2011.557522
更新日期:2011-05-01 00:00:00
abstract::Myeloid histocytes of dendritic cells (DCs), Langerhans cells (LCs), and macrophages in varied tissues, as leukemic blasts in acute monoblastic and monocytic leukemia (AML-M5a and M5b), are derived from monocyte progenitors in bone marrow. Based on DC induction from hematopoietic stem cells, myeloid progenitors, and m...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2015.1120838
更新日期:2016-01-01 00:00:00
abstract::Three cases of adamantinomatous craniopharyngiomas were examined by light and electron microscopy and special attention was paid to the formation of ossified tissue. The tumors were composed of neoplastic epithelial cells with keratinized cell nests and fibrous connective tissue. Keratinized cell masses sometimes dire...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/019131299281374
更新日期:1999-11-01 00:00:00
abstract::Hyaline inclusions were noted in cells of a typical synovial sarcoma following intra-arterial chemotherapy. Ultrastructural study revealed that the inclusions were cytoplasmic aggregates of intermediate filaments. Since the inclusions were not present in the tumor prior to treatment, it is suggested that they may have...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128209018553
更新日期:1982-10-01 00:00:00
abstract::A 15-year-old girl presented with a small, indolent mass near the knee joint. Light microscopy revealed a peculiar myxoid plexiform tumor composed of cytologically bland cells. Interpretation of the initial biopsy material was controversial. Subsequent immunohistochemical studies revealed tumor cells to be strongly re...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129309027771
更新日期:1993-05-01 00:00:00
abstract::Pathologic changes induced in the small intestine of suckling mice by rotavirus infection were studied by conventional histology, immunofluorescence, scanning electron microscopy, and electron microscopy of ultrathin sections. Infection could be detected within 24 hours in a few mice, but after 2 days it was well esta...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128109031504
更新日期:1981-01-01 00:00:00
abstract::To investigate the effects of X-ray irradiation on the proliferation and apoptosis of MCF-7 breast cancer cells; MCF-7 breast cancer cells were irradiated with X-ray. After irradiation, morphological changes and growth inhibition rate of the irradiated cells were observed under an inverted microscope. 3-(4,5-dimethylt...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2013.861569
更新日期:2014-05-01 00:00:00
abstract::In the last two decades, the ability of mesangial cells to respond to various stimuli or injurious agents by altering their phenotype and function has become recognized. The plasticity of these mesangial cells has been linked to the morphological and functional alterations responsible for the pathologic findings. Many...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.1080/01913120600932594
更新日期:2006-11-01 00:00:00
abstract::We report here ultrastructural and immunohistochemical studies of neuroblastic differentiation in the retrospective (n = 17) and prospective (n = 26) series of primitive neuroectodermal tumors (PNETs). By electron microscopy, neuritelike structures containing parallel-oriented microtubules, adhesive plaque junctions, ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129509064217
更新日期:1995-05-01 00:00:00
abstract::This study was aimed at identifying ultrastructural abnormalities that may be present in the duodenum of patients with chronic renal failure who were undergoing hemodialysis and that may have an effect on the normal absorptive function of the duodenum. Duodenal biopsy specimens from ten patients and four controls were...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129009050868
更新日期:1990-01-01 00:00:00
abstract::Inflammation in the liver is an extraintestinal manifestation that is frequently seen during inflammatory bowel diseases (IBD). The authors investigated histopathologycal, ultrastructural and antioxidant effects of dexmedetomidine (Dex) on liver during trinitrobenzene sulfonic acid (TNBS)-induced inflammatory bowel di...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2013.829150
更新日期:2015-02-01 00:00:00
abstract::Although the fine structure of extraneural sarcoidosis is well documented, ultrastructural study of central nervous system (CNS) sarcoidosis has been limited. Electron microscopic (EM) examination of 3 biopsy cases of CNS sarcoid revealed a mixed cellular population of lymphocytes, epitheloid cells, and multinucleated...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128109048309
更新日期:1981-07-01 00:00:00
abstract::Confocal microscope was used to analyze human enamel from 10 deciduous and 10 permanent teeth. Optically sectioned images were obtained. A more intense autofluorescence was found in primary teeth. This finding might be due to the greater presence of organic substances in deciduous enamel. The mean prism diameter measu...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2014.960544
更新日期:2015-04-01 00:00:00
abstract::Abstract Diagnosis of primary ciliary dyskinesia (PCD) by identification of dynein arm loss in transmission electron microscopy (TEM) images can be confounded by high background noise due to random electron-dense material within the ciliary matrix, leading to diagnostic uncertainty even for experienced morphologists. ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,随机对照试验
doi:10.3109/01913123.2013.815081
更新日期:2014-08-01 00:00:00
abstract::A slowly growing tumor in the right shoulder of a 38-year-old white male, which felt like a superficial cystic mass, was studied. The spindle cells, which represented the main component of the tumor, were arranged in a typical storiform pattern and were positive for CD34 and focally for CD117. The pigmented cells were...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120309935
更新日期:2003-05-01 00:00:00
abstract::One of the most constant and typical histological markers of thyroid papillary carcinoma is the presence of multilobated and ground-glass nuclei. With the intention of extending and characterizing the ultrastructural comprehension of this feature, thyroid papillary carcinoma cells and normal follicular cells were stud...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129809033471
更新日期:1998-05-01 00:00:00
abstract::Fabry disease is an X-linked recessive lysosomal storage disease caused by a deficiency of α-galactosidase A, with characteristic ultrastructural cytoplasmic myelin-like inclusions. Renal lesions are seen in male and variably in heterozygous female patients. One previous report has described Fabry disease involving a ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2010.538136
更新日期:2011-04-01 00:00:00
abstract::Testicular atrophy and testesterone insufficiency have been commonly reported associated with chronic liver diseases. Though testosterone dependent, the epididymal changes induced by liver disease have never been studied before. Thus, this study aimed to assess the ultrastructural events in the epididymis of rats with...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913123.2018.1488789
更新日期:2018-07-01 00:00:00
abstract::Lymphoma diagnosis rarely needs electron microscopy (EM), but one area where it can be useful is in the distinction of cytokeratin-positive lymphoma from carcinoma. The authors describe such a case, where difficulties were encountered due to lack of antibody specificity, distinguishing reactive from tumoral cells, and...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120802625830
更新日期:2009-01-01 00:00:00
abstract::This study aimed to examine the surface characteristics of erosive enamel in extracted human teeth by scanning electron microscopy. Morphologic changes in naturally eroded enamel depend on the stages of dental erosion. In its early stages, the enamel surfaces show a honeycomb appearance due to the dissolution of ename...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2015.1054014
更新日期:2015-01-01 00:00:00
abstract::Recently the authors have reported the potent beneficial effect of caffeic acid phenethyl ester (CAPE) on cholestatic oxidative liver injury induced by acute bile ligation in Swiss albino rats. Herein, they report the ultrastructural hepatocellular alterations induced by acute bile duct ligation and the effect of CAPE...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913121003788729
更新日期:2010-10-01 00:00:00
abstract::A glomangioma (glomus tumor) arising in the pituitary region is described. The histologic and ultrastructural features were characteristic. The tumor was composed of epithelioid cells arranged in an organoid fashion around vascular channels and contained scattered mast cells. Electron microscopy revealed tumor cells t...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128409141853
更新日期:1984-01-01 00:00:00
abstract::Mitochondrial morphology was studied in 60 renal epithelial neoplasms, including clear cell, papillary, chromophobe cell, and oncocytomas, to see if there are significant differences among the various subtypes. Mitochondria from the nephron tubular system obtained from 36 patients with glomerular diseases served as co...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129709021939
更新日期:1997-09-01 00:00:00