Diagnostic significance of mitochondria in four types of renal epithelial neoplasms: an ultrastructural study of 60 tumors.

Abstract:

:Mitochondrial morphology was studied in 60 renal epithelial neoplasms, including clear cell, papillary, chromophobe cell, and oncocytomas, to see if there are significant differences among the various subtypes. Mitochondria from the nephron tubular system obtained from 36 patients with glomerular diseases served as controls. Significant differences were found in mitochondrial ultrastructure in each of the subtypes of renal epithelial tumors. Novel observations were the presence of tubulovesicular cristae in many of the mitochondria found in chromophobe cell renal carcinomas and the discovery of a possible new oncocytic variant of this entity with mitochondria with pseudotubulovesicular and lamellar cristae similar to those of renal oncocytomas. This latter finding may be of prognostic significance, since renal oncocytomas are benign, while chromophobe cell neoplasms may behave in a malignant fashion.

journal_name

Ultrastruct Pathol

authors

Erlandson RA,Shek TW,Reuter VE

doi

10.3109/01913129709021939

subject

Has Abstract

pub_date

1997-09-01 00:00:00

pages

409-17

issue

5

eissn

0191-3123

issn

1521-0758

journal_volume

21

pub_type

杂志文章
  • Neutrophil fate in gingival crevicular fluid.

    abstract::The fate of the neutrophils within the inflammatory exudate in the periodontal crevice and their possible participation in the formation of neutrophil extracellular traps (NETs) are of clinical interest. However, the cytological analysis of clinical samples of inflammatory exudate is restricted by the obtainable quant...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913120903419989

    authors: Vitkov L,Klappacher M,Hannig M,Krautgartner WD

    更新日期:2010-02-01 00:00:00

  • Ultrastructural myopathology in the molecular era.

    abstract::Electron microscopy is an essential component of myopathology, both in diagnostics and research of neuromuscular diseases. Although recently reduced in the diagnostic armamentarium, it has greatly been expanded to mouse models in research. Mostly it is descriptive, but a few additional techniques in combination with t...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章,评审

    doi:10.3109/01913123.2013.810690

    authors: Goebel HH,Stenzel W

    更新日期:2013-10-01 00:00:00

  • Scanning Electron Microscope Characterization of Erosive Enamel in Human Teeth.

    abstract::This study aimed to examine the surface characteristics of erosive enamel in extracted human teeth by scanning electron microscopy. Morphologic changes in naturally eroded enamel depend on the stages of dental erosion. In its early stages, the enamel surfaces show a honeycomb appearance due to the dissolution of ename...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2015.1054014

    authors: Worawongvasu R

    更新日期:2015-01-01 00:00:00

  • 5'-CpG island methylation of the FHIT gene is associated with reduced protein expression and higher clinical stage in cervical carcinomas.

    abstract::Aberrant transcription of the FHIT gene has been observed in many solid tumors, suggesting that 5'-CpG island methylation of the FHIT gene is involved in tumor development. The authors investigated the status of the 5'-CpG island methylation of the FHIT gene and protein expression in a series of 40 cervical carcinomas...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120390250329

    authors: Wu Q,Shi H,Suo Z,Nesland JM

    更新日期:2003-11-01 00:00:00

  • As you like it, Part 3: A critique and historical review of calcification as seen with the electron microscope.

    abstract::As You Like It, Part 3, is a continuation of the lectures given by the author (Ultra Path VIII and Ultra Path IX). It is a critical historical review of topics of interest to electron microscopists, attempting to show what went wrong and perhaps also why. The topics chosen this time demonstrate the prominent role elec...

    journal_title:Ultrastructural pathology

    pub_type: 历史文章,杂志文章,评审

    doi:10.1080/019131201300343874

    authors: Ghadially FN

    更新日期:2001-05-01 00:00:00

  • Myxoid liposarcoma: study of ten cases.

    abstract::The ultrastructure of 10 myxoid liposarcomas from 9 patients is presented. Features closely resembling those of developing fetal adipose tissue were seen in all tumors. THe various cell types identified ranged from undifferentiated cells to typical multivacuolated and univacuolated lipoblasts. In addition, a secretory...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913128009141413

    authors: Battifora H,Nunez-Alonso C

    更新日期:1980-04-01 00:00:00

  • Sclerosing stromal tumor of the ovary: an ultrastructural and immunohistochemical analysis with histogenetic considerations.

    abstract::Sclerosing stromal tumors are rare, benign ovarian neoplasms of unknown etiology and histogenesis. Three sclerosing stromal tumors were evaluated by immunohistochemistry and electron microscopy and were compared to two thecomas and nonneoplastic ovarian mesenchymal tissue. The sclerosing stromal tumors and thecomas we...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129209061364

    authors: Shaw JA,Dabbs DJ,Geisinger KR

    更新日期:1992-05-01 00:00:00

  • Primitive neuroectodermal tumors: ultrastructural and immunohistochemical studies.

    abstract::We report here ultrastructural and immunohistochemical studies of neuroblastic differentiation in the retrospective (n = 17) and prospective (n = 26) series of primitive neuroectodermal tumors (PNETs). By electron microscopy, neuritelike structures containing parallel-oriented microtubules, adhesive plaque junctions, ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129509064217

    authors: Papierz W,Alwasiak J,Kolasa P,Wegrzyn Z,Zakrzewski K,Polis L,Debiec-Rychter M,Liberski PP

    更新日期:1995-05-01 00:00:00

  • Ultrastructural phenotype of "intestinal-type" cells in columnar-lined esophagus.

    abstract::An intestinal-type epithelium is often present at columnar-lined esophagus, gastroesophageal junction or within the so-called short segment Barrett's esophagus, but ultrastructural study failed to detect enterocytes in columnar-lined esophagus. The authors have analyzed the intestinal aspects present in areas of colum...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120252959281

    authors: Sbarbati A,Faccioli N,Ricci F,Merigo F,Benati D,Castaldini G,Cordiano C,Osculati F

    更新日期:2002-03-01 00:00:00

  • Granular cell tumor: a review of the pathology and histogenesis.

    abstract::As the name suggests, the histogenesis of the granular cell tumor is uncertain, but this intriguing neoplasm has occasioned much speculation and controversy since its description in 1926 as a myoblastoma. Though ubiquitous in its anatomic location, it is usually small, solitary, benign, and readily recognized by routi...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章,评审

    doi:10.1080/019131299281545

    authors: Ordóñez NG,Mackay B

    更新日期:1999-07-01 00:00:00

  • Monoclonal glomerulopathy with features of cryoglobulinemic glomerulopathy in murine multiple myeloma model.

    abstract::In vivo and animal models of monoclonal light chain-associated renal diseases are limited. The Vk*MYC transgenic model with multiple myeloma in 50-70 weeks old mice with renal involvement has been reported before, but detailed renal pathologic changes have not been well documented. This study fully investigated pathol...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913123.2020.1841349

    authors: Zhang PL,Herrera GA,Liu B

    更新日期:2020-11-20 00:00:00

  • Epithelioid variant of pleomorphic liposarcoma: a comparative immunohistochemical and ultrastructural analysis of six cases with emphasis on overlapping features with epithelial malignancies.

    abstract::Pleomorphic liposarcoma (PL) is the least common subtype of liposarcoma, displaying a lipoblastic, malignant fibrous histiocytoma (MFH)-like and, less frequently, an epithelioid growth pattern. The epithelioid morphology in PL is still underrecognized and may closely simulate other epithelial neoplasms, mainly adrenal...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120290104575

    authors: Huang HY,Antonescu CR

    更新日期:2002-09-01 00:00:00

  • Ultrastructural morphologic changes in mycobacterial biofilm in different extreme condition.

    abstract::The aim of this study was to investigate the morphologic and ultrastructural features of biofilms of slow and fast-growing mycobacteria in different stress conditions, presence and absence of oleic acid albumin dextrose catalase (OADC) enrichment and at different temperatures: 30, 37 and 42 °C. Four hundred mycobacter...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2014.950780

    authors: Kumar V,Sachan TK,Sharma P,Rawat KD

    更新日期:2015-02-01 00:00:00

  • Swim exercise training ameliorates hepatocyte ultrastructural alterations in rats fed on a high fat and sugar diet.

    abstract::Excessive consumption of carbohydrate and fat increases the risk of liver disease. We hypothesized that swim exercise can protect hepatocytes from ultra-structural damage induced by high cholesterol and fructose diets (HCFD). Rats were either fed with HCFD (model group) or a standard laboratory chow (control group) fo...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913123.2017.1422581

    authors: Dallak MA,Bin-Jaliah I,Albawardi A,Haidara MA,Sakr HF,Eid RA,Hassan WN,Al-Ani B

    更新日期:2018-03-01 00:00:00

  • Chromogranin A and vesicular monoamine transporter 2 immunolocalization in protein bodies of human locus coeruleus neurons.

    abstract::Our previous histochemical and ultrastructural studies have identified, in human catecholamine neurons, abundant spherical acidophilic protein bodies (pb), which originate from regular mitochondria, retaining their double membrane. In locus coeruleus (LC) neurons, pb have somatodendritic distribution and are unequivoc...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2012.750410

    authors: Kloukina-Pantazidou I,Chrysanthou-Piterou M,Havaki S,Issidorides MR

    更新日期:2013-04-01 00:00:00

  • The effect of sibutramine, a serotonin-norepinephrine reuptake inhibitor, on platelets and fibrin networks of male Sprague-Dawley rats: a descriptive study.

    abstract::Sibutramine is used in the treatment of obesity due to its ability to influence feelings of hunger and satiety by inhibiting the re-uptake of serotonin and noradrenalin in the central nervous system (CNS). Sibutramine use has been associated with numerous adverse events in particular cardiovascular complications possi...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2014.946635

    authors: van der Schoor C,Oberholzer HM,Bester MJ,van Rooy MJ

    更新日期:2014-12-01 00:00:00

  • Ultrastructural changes in epithelial cells of rats exposed to low concentration of hydrogen sulfide for 50 days.

    abstract::Hydrogen sulfide (H2S) and other volatile sulfur compounds (VSCs) appear mainly in the oral air of patients with halitosis. It seems that VSCs are directly involved in the pathogenesis of gingival diseases. In previous studies, short-term (7 hours-4 days), high concentrations (5-400 ppm) of H2S applications on periodo...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913123.2016.1234530

    authors: Yalçın Yeler D,Aydın M,Hocaoğlu PT,Koraltan M,Özdemir H,Kotil T,Gül M

    更新日期:2016-11-01 00:00:00

  • Myoepithelial cells in lobular carcinoma in situ of the breast: a parallel immunocytochemical and ultrastructural study.

    abstract::The distribution and morphology of myoepithelial cells in one case of normal breast and in 4 cases of lobular carcinoma in situ (LCIS) were studed by immunoperoxidase and immunofluorescence with anti-actin antisera and by electron microscopy. The actin-rich cells appeared to lay flattened on the basement membrane, or ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913128109048305

    authors: Bussolati G,Botto Micca FB,Eusebi V,Betts CM

    更新日期:1981-07-01 00:00:00

  • Subacute inflammatory polyneuropathy: two cases with plasmacytoid histiocytes in the endoneurium.

    abstract::Inflammatory polyneuropathies are mainly known by their acute form, Guillain-Barré syndrome, but there are also chronic cases and all are considered as having an autoimmune mechanism. In each form, peripheral nerve biopsies show scattered macrophages in the endoneurium and in certain cases macrophages invade the Schwa...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129809103359

    authors: Vital C,Vital A,Lagueny A,Larribau E,Saintarailles J,Julien J

    更新日期:1998-09-01 00:00:00

  • Immunogold detection of chromogranin A in the neuroendocrine tumor.

    abstract::Immunogold ultrastructural localization of chromogranin A in secretory granules within tumor cells provides convincing evidence of endocrine or neuroendocrine differentiation. A modified immunogold method (designed for use on osmicated tissue) produced positive labeling of small granules not only in well-differentiate...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129309015402

    authors: Silver MM,Lines LD,Hearn SS

    更新日期:1993-01-01 00:00:00

  • Endothelial injury of capillaries in the stria vascularis of guinea pigs treated with cisplatin and gentamicin.

    abstract::The drugs cisplatin and gentamicin are used for treatment of various cancer patients suffering from infection. The authors report a detailed electron microscopic study of blood vessels in stria vascularis of guinea pigs after treatment with cisplatin alone and in combination with gentamicin. The most distinctive featu...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129709021925

    authors: Kohn S,Fradis M,Podoshin L,Ben-David J,Zidan J,Robinson E

    更新日期:1997-05-01 00:00:00

  • Adult neuroblastoma of bone: a case report.

    abstract::Adult neuroblastoma is an uncommon tumor and it is rare for one to present as a primary bone lesion. We report the case of a 23-year-old man in whom the tumor initially appeared in the right scapula. Light microscopic, immunocytochemical, and electron microscopic findings were typical of neuroblastoma. ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913128709048440

    authors: Mackay B,Ordóñez NG

    更新日期:1987-01-01 00:00:00

  • Abnormal cutaneous nerves in incontinentia pigmenti.

    abstract::Cutaneous nerves showed multiple ultrastructural abnormalities in a patient with incontinentia pigmenti. Fetal nerve bundles were seen both in the dermis and entering the epidermis. A cell with some Schwann cell features was identified above the basal layer amid keratinocytes. Dermal melanophages were in close apposit...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913128809064214

    authors: Worret WI,Nordquist RE,Burgdorf WH

    更新日期:1988-01-01 00:00:00

  • Neuronal ceroid lipofuscinosis: an ultrastructural, genetic, and clinical study report.

    abstract::The term "neuronal ceroid lipofuscinosis" (NCL) describes a complex of inherited neurodegenerative conditions associated with storage of lipopigments in brain tissue. In 1989 Dyken proposed a classification of NCL based on the age, clinical symptoms, and ultrastructural aspects of the lipopigments. At the ultrastructu...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/019131201300004681

    authors: Boldrini R,Biselli R,Santorelli FM,Bosman C

    更新日期:2001-01-01 00:00:00

  • A new tool improves diagnostic test performance for transmission em evaluation of axonemal dynein arms.

    abstract::Abstract Diagnosis of primary ciliary dyskinesia (PCD) by identification of dynein arm loss in transmission electron microscopy (TEM) images can be confounded by high background noise due to random electron-dense material within the ciliary matrix, leading to diagnostic uncertainty even for experienced morphologists. ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/01913123.2013.815081

    authors: Funkhouser WK 3rd,Niethammer M,Carson JL,Burns KA,Knowles MR,Leigh MW,Zariwala MA,Funkhouser WK Jr

    更新日期:2014-08-01 00:00:00

  • Chondrosarcoma with myxoid change: a study using a quick-freezing and deep-etching method.

    abstract::A middle-aged Japanese woman visited the Orthopedics Department of Nihon University Nerima Hikarigaoka Hospital complaining of pain in the left hip joint that had started approximately 8 months earlier. Following several examinations, including imaging diagnoses, an incisional biopsy demonstrated a malignant acetabula...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120701515272

    authors: Hemmi A,Osaka S,Sumie O,Nemoto N,Ohno N,Terada N,Fujii Y,Ohno S

    更新日期:2007-07-01 00:00:00

  • Fatal pulmonary microsporidiosis due to encephalitozoon cuniculi following allogeneic bone marrow transplantation for acute myelogenous leukemia.

    abstract::Microsporidia are ubiquitous obligate eukaryotic intracellular parasites that are now felt to be more akin to degenerate fungi than to protozoa. Microsporidia can be highly pathogenic, causing a broad range of symptoms in humans, especially individuals who are immunocompromised. The vast majority of human cases of mic...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120590951257

    authors: Orenstein JM,Russo P,Didier ES,Bowers C,Bunin N,Teachey DT

    更新日期:2005-05-01 00:00:00

  • Clear cell leiomyoma (leiomyoblastoma) of the uterus: ultrastructural observations.

    abstract::The ultrastructure of a benign uterine epithelioid leiomyoma with prominent clear cells ("leiomyoblastoma") was studied to define the subcellular changes that yield the distinctive light microscopic pattern of this rare lesion. The main constituent of the cytoplasm was multiple cytolysosomes composed of vesicular, mem...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913128609032224

    authors: Mazur MT,Priest JB

    更新日期:1986-01-01 00:00:00

  • Beneficial effect of caffeic acid phenethyl ester (CAPE) on hepatocyte damage induced by bile duct ligation: an electron microscopic examination.

    abstract::Recently the authors have reported the potent beneficial effect of caffeic acid phenethyl ester (CAPE) on cholestatic oxidative liver injury induced by acute bile ligation in Swiss albino rats. Herein, they report the ultrastructural hepatocellular alterations induced by acute bile duct ligation and the effect of CAPE...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913121003788729

    authors: Eşrefoğlu M,Ara C

    更新日期:2010-10-01 00:00:00

  • Dysembryoplastic neuroectodermal tumor: an ultrastructural study of six cases.

    abstract::Dysembryoplastic neuroectodermal tumor (DNT) is a rare brain neoplasm. Although the tumor pathology is relatively well charactererized, its full clinicopathological spectrum is still discussed, and ultrastructural data on it are very limited. Here, the authors describe detailed ultrastructural pathology of 7 cases of ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/019131201753343494

    authors: Biernat W,Liberski PP,Kordek R,Zakrzewski K,Polis L,Budka H

    更新日期:2001-11-01 00:00:00