A family study of the genetic basis of asthma and wheezy bronchitis.

abstract：:If cord blood IgE is used to detect those predisposed to become allergic it is important to define appropriately the normal values for this measurement. A commonly cited cut off point is 1.0 IU/ml. We analysed 5353 cord blood samples for IgE by means of an enzyme linked immunosorbent assay. Descriptive statistics of t...

journal_title：Archives of disease in childhood

authors： Kimpen J,Callaert H,Embrechts P,Bosmans E

更新日期：1987-05-01 00:00:00

abstract：:Two investigations of paediatric manpower in England, Wales, and Northern Ireland were carried out, each using a different method. The first survey located registrars and senior registrars and checked on their occupational status 3 years later in order to see which ones had been promoted. Loss factors--such as emigrat...

journal_title：Archives of disease in childhood

authors： Liberman MM,Bellman MH

更新日期：1982-09-01 00:00:00

abstract：:In a prospective follow up of 116 high risk infants, a 24 hour behavioural chart on seven consecutive days was analysed at seven and 12 weeks of age. Of children who manifested atopic disease at 2 years, 44/116 (38%), had shown significantly more fussing during the seventh, and colic type cry during the twelfth week t...

journal_title：Archives of disease in childhood

authors： Kalliomäki M,Laippala P,Korvenranta H,Kero P,Isolauri E

更新日期：2001-04-01 00:00:00

abstract：:Three cases are reported in which thrombi were found in the aorta at postmortem. In each case the thrombus had originated within the ductus arteriosus. We believe that in recent years the attention paid to the presence of indwelling cannulae as a cause of embolic phenomena in the newborn period has led to a reduction ...

journal_title：Archives of disease in childhood

authors： Knowlson GT,Marsden HB

更新日期：1978-02-01 00:00:00

abstract：:Over a 25 year period, 31 asthmatic children received artificial ventilation for acute asthma at Alder Hey Children's Hospital on 48 occasions. Altogether 47 episodes occurred from 1971-89, with no decline in the number of episodes per year (mean 2.5) over this period. Eight children died during intermittent positive ...

journal_title：Archives of disease in childhood

authors： Seddon PC,Heaf DP

更新日期：1990-12-01 00:00:00

abstract：AIM:To investigate the rate and nature of anxiety symptoms and disorders in children, and their relation to social adversities in a cultural sample not previously researched. METHODS:237 children aged 9 to 13 years living in the Gaza Strip were selected randomly from 112 schools. Children completed the revised manifes...

journal_title：Archives of disease in childhood

authors： Thabet AA,Vostanis P

更新日期：1998-05-01 00:00:00

abstract：:The introduction of chemoprophylaxis with rifampicin and isoniazid in 1981 significantly reduced the incidence of tuberculosis. Between 1978 and 1981 children accounted for 136 of 642 notified cases, and this was reduced to 55 of 418 between 1982 and 1986. This effect was most obvious among children from the Indian su...

journal_title：Archives of disease in childhood

authors： Ormerod LP

更新日期：1987-10-01 00:00:00

abstract：:We identified 410 infants who were not walking independently by the age of 18 months from among a geographically defined population of 4275 infants who either were born weighing less than 2000 g or had needed admission to the special care nursery in the neonatal period. The outcome of the late walkers was ascertained ...

journal_title：Archives of disease in childhood

authors： Johnson A,Goddard O,Ashurst H

更新日期：1990-05-01 00:00:00

abstract：OBJECTIVES:To assess factors associated with granting of the Disability Living Allowance (DLA) for Down syndrome. DESIGN:Cross-sectional survey. SETTING:Families with a child with Down syndrome enrolled in a community-based trial of vitamin supplementation. PARTICIPANTS:156 children with trisomy 21 (59% male, 20% no...

journal_title：Archives of disease in childhood

authors： Ellis J,Logan S,Pumphrey R,Tan HK,Henley W,Edwards V,Moy R,Gilbert R

更新日期：2008-01-01 00:00:00

abstract：:Five cases of serious injuries to children wearing superhero costumes, involving extreme risk-taking behaviour, are presented here. Although children have always displayed behaviour seemingly unwise to the adult eye, the advent of superhero role models can give unrealistic expectations to the child, which may lead to ...

journal_title：Archives of disease in childhood

authors： Davies P,Surridge J,Hole L,Munro-Davies L

更新日期：2007-03-01 00:00:00

abstract：AIM:To produce a growth reference for British children with Williams syndrome. METHODS:The children and adults recruited into the study were all affiliated to the Williams Syndrome Foundation, a parent support group founded in 1979. They have all been shown to have a deletion of chromosome 7q11.23. One growth nurse (W...

journal_title：Archives of disease in childhood

authors： Martin ND,Smith WR,Cole TJ,Preece MA

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:Assays based on interferon gamma (IFNgamma) are an exciting new development for screening for latent tuberculosis infection (LTBI) in adults, but there are limited data on their effectiveness in children. Nevertheless new National Institute for Health and Clinical Excellence (NICE) guidelines recommend their ...

journal_title：Archives of disease in childhood

authors： Taylor RE,Cant AJ,Clark JE

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:To examine the role of viruses in febrile seizures (FS) by comparing the relative risk (RR) of developing FS with common viral infections and subsequent risk of recurrence. METHODS:We matched the medical records of all children admitted with FS over 5 years and the contemporary records for all admissions fo...

journal_title：Archives of disease in childhood

authors： Chung B,Wong V

更新日期：2007-07-01 00:00:00

abstract：:Partial splenectomy was performed on 30 patients with homozygous beta thalassaemia to reduce blood requirements and to avoid the risk of overwhelming postsplenectomy infections; 24 patients had thalassaemia major and six thalassaemia intermedia. Five patients received a high transfusion regimen before and after surger...

journal_title：Archives of disease in childhood

authors： de Montalembert M,Girot R,Revillon Y,Jan D,Adjrad L,Ardjoun FZ,Belhani M,Najean Y

更新日期：1990-03-01 00:00:00

abstract：:In 20 children needing treatment for symptomatic sick sinus syndrome, the average age at presentation was 7.1 years and ranged from 9 months to 18 years. Symptoms were never precise but, in retrospect, 5 children had syncope, 7 had a rapid heart action, 6 had dyspnoea or tachypnoea, 2 had nonspecific chest pains, 2 ha...

journal_title：Archives of disease in childhood

authors： Radford DJ,Izukawa T

更新日期：1975-11-01 00:00:00

abstract：OBJECTIVE:Search for evidence supporting target age, level of intervention and target values for low-density lipoprotein (LDL) cholesterol levels in children with familial hypercholesterolemia. DESIGN:Systematic review and meta-analysis. PubMed, Medline, CINAHL and Cochrane Reviews databases from 1966 to 2007 were sea...

journal_title：Archives of disease in childhood

authors： Lebenthal Y,Horvath A,Dziechciarz P,Szajewska H,Shamir R

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Congenital facial palsy (CFP) is clinically defined as facial palsy present at birth. It is associated with considerable disfigurement and causes functional and emotional problems for the affected child. The aetiology of the majority of cases however, remains elusive. AIMS:To investigate the role of a neuro...

journal_title：Archives of disease in childhood

authors： Jemec B,Grobbelaar AO,Harrison DH

更新日期：2000-09-01 00:00:00

abstract：:A four year regional screening programme to detect cystic fibrosis using measurement of immunoreactive trypsinogen is described. During this period 60 infants were diagnosed; 34 by screening, 12 born with meconium ileus, and 14 not identified by the screening assay but who presented with clinical symptoms at a later a...

journal_title：Archives of disease in childhood

authors： Roberts G,Stanfield M,Black A,Redmond A

更新日期：1988-12-01 00:00:00

abstract：:Plasma amino acids were measured in 35 preterm infants, of whom 11 weighed less than 1000 g and 24 weighed between 1000 g and 1500 g at the time of sampling. Repeat samples were obtained in 18 at least seven days later. Seventeen infants were fed with preterm formula milk and 18 with expressed maternal breast milk at ...

journal_title：Archives of disease in childhood

authors： Ventura V,Brooke OG

更新日期：1987-12-01 00:00:00

abstract：:General practice records of 1058 children were studied to determine the incidence, prevalence, natural history, diagnosis, and treatment of wheezing presenting in the first 21 years of life. Up to 7 years of age, boys were more likely to present with wheeze and to have recurrent episodes. Later there was a higher inci...

journal_title：Archives of disease in childhood

authors： Strachan DP

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVES:To assess the efficacy and safety of polyethylene glycol 3350 plus electrolytes (PEG+E) for the treatment of chronic constipation in children. DESIGN:Randomised, double blind, placebo controlled crossover trial, with two 2-week treatment periods separated by a 2-week placebo washout. SETTING:Six UK paediat...

journal_title：Archives of disease in childhood

authors： Thomson MA,Jenkins HR,Bisset WM,Heuschkel R,Kalra DS,Green MR,Wilson DC,Geraint M

更新日期：2007-11-01 00:00:00

abstract：AIM:To determine the incidence of hypocalcaemia in critically ill children with meningococcal disease. METHODS:In a prospective cohort study, 70 of 80 patients admitted consecutively with a clinical diagnosis of meningococcal disease to intensive care had measurements of total and ionised calcium on admission. Paratho...

journal_title：Archives of disease in childhood

authors： Baines PB,Thomson AP,Fraser WD,Hart CA

更新日期：2000-12-01 00:00:00

abstract：:Sleep related arterial oxygen desaturation has been described in clinically stable young adults with cystic fibrosis. The incidence and severity of nocturnal oxygen desaturation in children during infective exacerbations and the changes that occur with treatment were examined. Forty five children with proved cystic fi...

journal_title：Archives of disease in childhood

authors： Allen MB,Mellon AF,Simmonds EJ,Page RL,Littlewood JM

更新日期：1993-08-01 00:00:00

abstract：:Life was sorted. With membership of the college under my belt, and my paediatric training completed, I needed a new challenge. I decided to launch into the deep waters of qualitative research. Stepping out with some trepidation into semistructured interviews and grounded theory, I soon found that the water was neither...

journal_title：Archives of disease in childhood

authors： Sidebotham P

更新日期：2003-01-01 00:00:00

abstract：:The concentration of 27 amino acids in the vitreous humour was analysed in 120 cot deaths. Baseline data for age and postmortem interval are presented and the concentrations compared with the normal reference range for plasma. The results do not indicate that a specific aminoacidopathy is a factor in cot deaths. ...

journal_title：Archives of disease in childhood

authors： Patrick WJ,Logan RW

更新日期：1988-06-01 00:00:00

abstract：:Mechanisms of gastro-oesophageal reflux were studied by oesophageal manometry and pH monitoring in 33 children: nine controls, 15 with gastro-oesophageal reflux alone, and nine with reflux oesophagitis. A total of 122 episodes of reflux were analysed in detail: 82 (67%) were synchronous with swallowing and 40 (33%) as...

journal_title：Archives of disease in childhood

authors： Mahony MJ,Migliavacca M,Spitz L,Milla PJ

更新日期：1988-11-01 00:00:00

abstract：:This review focuses on recent advances of topical interest regarding the diagnosis and treatment of common causes of bacterial meningitis occurring in children beyond the neonatal period. Tuberculous meningitis is beyond the scope of this review. ...

journal_title：Archives of disease in childhood

authors： El Bashir H,Laundy M,Booy R

更新日期：2003-07-01 00:00:00

abstract：:Immunohistochemical studies of pancreatic tissue from patients with cystic fibrosis associated with diabetes mellitus (CFDM) show increased numbers of somatostatin secreting delta cells. To look for a possible functional correlate to this finding basal and arginine stimulated plasma somatostatin and serum C peptide co...

journal_title：Archives of disease in childhood

authors： Meacham LR,Caplan DB,McKean LP,Buchanan CN,Parks JS,Culler FL

更新日期：1993-01-01 00:00:00

abstract：:The age distribution of anginose infectious mononucleosis in children was analysed retrospectively for the years 1966-85. During that period the disease became significantly more common in children of a young age and less common in older children. This shift could not be attributed either to socioeconomic conditions o...

journal_title：Archives of disease in childhood

authors： Spirer Z,Holtzman M,Melamed I,Shalit I

更新日期：1987-06-01 00:00:00

abstract：:After the introduction of the colposcope for the examination of children suspected of being sexually abused in Leeds, a study was undertaken to describe the findings in detail. A total of 109 consecutive prepubertal girls, mean age 70.4 months were assessed including colposcopic genital and anal examination, and peer ...

journal_title：Archives of disease in childhood

authors： Hobbs CJ,Wynne JM,Thomas AJ

更新日期：1995-11-01 00:00:00