Abstract:
:Systolic blood pressure was measured weekly in conscious and in anesthetized female Sprague-Dawley (SD) and Wistar-Furth (W/Fu) rats following adrenal enucleation, unilateral nephrectomy, and the imposition of a high salt intake. SD rats quickly developed adrenal-regeneration hypertension (ARH) which progressed rapidly, and was identifiable in both the conscious and the anesthetized state. W/Fu rats slowly developed mild ARH, which, with a single exception, was identifiable only in conscious animals; the arterial pressures were within the normotensive range under anesthesia. The depressor effect of ether was also greater in adrenal-enucleated W/Fu than in similarly prepared SD rats, and in hypertensives than in normotensives. It is concluded that blood pressure measurements taken under anesthesia may not be representative of the true resting blood pressures: this is likely to be a particularly crucial problem in identifying early hypertension under circumstances and in rat strains highly susceptible to the depressor effects of ether.
journal_name
Can J Physiol Pharmacoljournal_title
Canadian journal of physiology and pharmacologyauthors
Hall CE,Nasseth Ddoi
10.1139/y78-165subject
Has Abstractpub_date
1978-12-01 00:00:00pages
1036-40issue
6eissn
0008-4212issn
1205-7541journal_volume
56pub_type
杂志文章abstract::We examined the interaction of smooth muscle myosin with alpha-actin and beta-actin isoforms during the contraction of A7r5 smooth muscle cells and rat aortic smooth muscle. The techniques of confocal microscopy and fluorescence resonance energy transfer (FRET) analysis were utilized in examining A7r5 cells and rat ao...
journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
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更新日期:2009-05-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
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更新日期:1997-05-01 00:00:00
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更新日期:2018-01-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:1987-05-01 00:00:00
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更新日期:1994-07-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/cjpp-2018-0691
更新日期:2019-11-01 00:00:00
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pub_type: 杂志文章
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