Abstract:
:A 40-year-old man suffering from amyotrophic lateral sclerosis with symmetrical degeneration of the thalamus and the substantia nigra is reported. The distribution pattern of the thalamic degeneration in the present case was characteristic in that the Nucleus centralis was the severest affected of the thalamic nuclei. As far as we know, there is no such case of amyotrophic lateral sclerosis in the literature. Nosologically, this case may represent a form of combined heredosystemic degeneration.
journal_name
Acta Neuropatholjournal_title
Acta neuropathologicaauthors
Kosaka K,Mehraein Pdoi
10.1007/BF00691074subject
Has Abstractpub_date
1978-12-15 00:00:00pages
241-4issue
3eissn
0001-6322issn
1432-0533journal_volume
44pub_type
杂志文章abstract::The mechanisms underlying neurodegenerative diseases are the outcome of pathological alterations of evolutionary conserved molecular and cellular cascades. For this reason, Drosophila and C. elegans serve as useful model systems to study various aspects of neurodegenerative diseases. Here, we introduce the advantageou...
journal_title:Acta neuropathologica
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