Abstract:
:Phenylephrine hydrochloride is a potent, effective, relatively safe drug with few ocular side effects. Side effects from topical instillation are uncommon but include severe systemic cardiovascular effects with elevated blood pressure and stroke. Ten percent phenylephrine should be used with caution in patients with known cardiac disease, hypertension, aneurysms, long-standing insulin-dependent diabetes, or advanced arteriosclerosis. A 2.5% concentration is generally indicated for ophthalmic examination as well as for use in infants and in the elderly. Phenylephrine should not be used in patients with narrow-angle glaucoma, and it is also contraindicated in patients taking monoamine oxidase inhibitors or tricyclic antidepressants.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Meyer SM,Fraunfelder FTdoi
10.1016/s0161-6420(80)35108-7subject
Has Abstractpub_date
1980-11-01 00:00:00pages
1177-80issue
11eissn
0161-6420issn
1549-4713pii
S0161-6420(80)35108-7journal_volume
87pub_type
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