[Study of Urinary excretion of total, free, and non-dialysable conjugated hydroxyproline in paraplegics].

Abstract:

:Eighteen paraplegics with or without neurogenic osteo-arthropathy (POAN) were evaluated for variations in their urinary excretion levels of total (T), and free (L) hydroxyproline and its non-dialysable (ND) and dialysable (D) peptide fractions. Increases in urinary hydroxyproline, moderate rises in free hydroxyproline and more substantial increases in dialysable and non-dialysable peptide fractions could be observed in these patients who all were affected with osteoporosis of disuse. Only variations in dialysable hydroxyproline could be used to differentiate between POAN + and POAN - patients. Of the various ratios which were analyzed (ND/T, L/ND, and D/ND), the D/ND ratio appears to be the most useful for diagnosis and monitoring of patients with POAN.

journal_name

Ann Biol Clin (Paris)

authors

Pilonchery G,Finck C,Minaire P,Messy P,Revol A

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

315-9

issue

4

eissn

0003-3898

issn

1950-6112

journal_volume

40

pub_type

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