[Prenatal diagnosis of Down syndrome: study of correlations between two types of blood collection tubes].

abstract：:Con A stimulated lymphocytes from some patients with primary glomerular disease release in vitro a lymphokine, the vascular permeability factor (VPF). House dust sensitization was early reported among these patients. We therefore studied the action of this specific mitogen on VPF production in 58 patients with primary...

journal_title：Annales de biologie clinique

authors： Laurent J,Heslan JM,Branellec A,Lagrue G

更新日期：1984-01-01 00:00:00

abstract：:Two cases of newborn haemolytic disease because of ABO incompatibility are reported. In both cases, blood erythroblastosis exceeded 300 per 100 leukocytes at birth. Both newborns developed early jaundice and one presented with anaemia. Intensive phototherapy begun soon after birth was an effective treatment. The diagn...

journal_title：Annales de biologie clinique

authors： Palleau S,Le Tourneau C,Jrad I,Andreux JP,Gouin I,Siguret V

更新日期：2004-05-01 00:00:00

abstract：:We quantify the impact of several variables including site of blood draw, delay in measurement, and use of the cyanide antidote hydroxocobalamin on detection of both normal (<2 mmol/L) and elevated (>6 mmol/L) human plasma lactate. An in vivo study assessed effects of venous or arterial origin of blood samples. Two in...

journal_title：Annales de biologie clinique

authors： Houzé P,Laforge M,Baud FJ

更新日期：2018-01-01 00:00:00

abstract：:Premature rupture of the membranes (PROM) is a frequent event affecting 3% of pregnancies. PROM causes 30% of premature deliveries and 20% of perinatal mortality. The diagnosis relies mainly on the clinical visualization of the amniotic fluid flow in the vagina. If not, clinicians can use bedside tests detecting eithe...

journal_title：Annales de biologie clinique

authors： Julien M,N'guema L,Bouzerara A,Toro B,Lecarpentier E,Guibourdenche J

更新日期：2018-06-01 00:00:00

abstract：:The evidence for disturbances of tryptophan and 5-hydroxytryptamine in depression and for various mechanisms by which such disturbances could occur is discussed. Two recent relevant studies in the author's laboratory are described: a) non-esterified fatty acid and total and free tryptophan were determined in plasmas o...

journal_title：Annales de biologie clinique

authors： Curzon G

更新日期：1979-01-01 00:00:00

abstract：:Insoluble elastin immobilised in Agar plates was used as substrate to quantitate the elastase inhibitory capacity of human sera. This technique was found valuable to evaluate the genetic deficiency of alpha-1-antitrypsin (Z phenotypes) and also the functional loss of the elastase inhibitory capacity in smokers. A sign...

journal_title：Annales de biologie clinique

authors： Bellon G,Hornebeck W,Lagrue G,Martin JP,Robert L

更新日期：1981-01-01 00:00:00

abstract：:It is often reminded that if the ionized calcium is not measured, the interpretation of total calcemia should consider serum albumin. Two formulas are usually employed: ["Corrected" Ca (mmol/L) = Ca measured (mmol/L) + 0.020 or 0.025 (40 - albumin (g/L))]. This adjustment formula arises from works of Payne published i...

journal_title：Annales de biologie clinique

authors： Parent X,Spielmann C,Hanser AM

更新日期：2009-07-01 00:00:00

abstract：:We describe the case of a serological reactivation in a Toxoplasma-seropositive subject, following a cardiac transplantation transmitting cysts contained in the myocardial tissue. In a context of acute graft rejection, primary chemoprophylaxis enables to avoid onset of opportunistic toxoplasmosis, emerging with immuno...

journal_title：Annales de biologie clinique

authors： Desoubeaux G,Perret-Gallix K,Machet MC,Sirinelli A,Bailly E,Van Langendonck N,Chandenier J

更新日期：2012-05-01 00:00:00

abstract：:The simultaneous presence of homogeneous and heterogeneous reactions at different binding sites of a multiepitope antigen makes the description of the kinetic parameters of the so called "one step" solid phase immunometric assays complex. The authors extended the "one step" approach to the concept of the "soluble sand...

journal_title：Annales de biologie clinique

authors： Chieregatti G,Massaglia A,Giraudi G,Zannino M,Barbieri U,Boniolo A

更新日期：1990-01-01 00:00:00

abstract：:Anti native DNA antibodies (anti nDNA Ab), which are a highly specific feature of systemic lupus erythematosus (SLE) were measured by 3 methods: an enzyme linked immunosorbent assay (ELISA), an indirect immunofluorescence test on Crithidia luciliae (IFCL) and the Farr assay (reference test). 114 sera from patients wit...

journal_title：Annales de biologie clinique

authors： Laplanche S,Diemert MC,Musset L,Abuaf N,Galli J

更新日期：1990-01-01 00:00:00

abstract：:The identification of a product absorbed by an opiate consumer is sometimes problematic since there is no specific biomarker for all molecules. We developed an ultra-high pressure liquid chromatography coupled to tandem mass spectrometry technique which allows the identification and the quantification of 25 opiates in...

journal_title：Annales de biologie clinique

authors： Dubois N,Counerotte S,Goffin E,Pirotte B,Charlier C

更新日期：2014-03-01 00:00:00

abstract：:Cystic fibrosis (CF) is the most common severe recessive disease in Caucasians. The gene responsible for the disease encodes a protein named cystic fibrosis transmembrane conductance regulator, which is predicted to function as a cAMP-regulated chloride channel. Reduced chloride secretion is at the basis of insufficie...

journal_title：Annales de biologie clinique

authors： Ferrari M,Cremonesi L

更新日期：1996-01-01 00:00:00

abstract：:The authors describe a method of fractionation of urinary 17-oxosteroids after purification of the urinary extract by Girard's T reagent. After solvolysis, enzyme hydrolysis and purification by Girard's T reagent, the 17-oxosteroids were estimated in the form of trimethyl silyl ethers by gas liquid chromatographye on ...

journal_title：Annales de biologie clinique

authors： Habrioux G

更新日期：1978-01-01 00:00:00

abstract：:Acquired hemophilia A (AHA) is a rare and potentially severe bleeding disorder caused by circulating autoantibodies directed against factor (F) VIII. Apart from idiopathic cases, AHA is associated with autoimmune diseases, cancers, use of medications, pregnancy and the post-partum period. We report the case of a 78-ye...

journal_title：Annales de biologie clinique

authors： Sourdeau É,Clauser S,Prud'Homme R,Bardet V,Calmette L

更新日期：2019-04-01 00:00:00

abstract：:Haloperidol is extracted with hexane-isoamyl alcohol in the presence of two internal standards, chlorohaloperidol and spiroperidol. For chromatographic separation, a C18 reversed-phase column and a mobile phase of acetonitrile/methanol/phosphate buffer are used. Detection is by UV absorption spectrophotometry at 245 n...

journal_title：Annales de biologie clinique

authors： Hequet D,Jarry C,Rouquette C,Brachet-Liermain A

更新日期：1985-01-01 00:00:00

abstract：:43, patients, subjected to cervical cytology, colposcopy and colposcopic directed biopsy, were found to have lesions suggestive of human Papillomavirus (HPV) infection by one or more parameters. Immunohistochemical staining for HPV antigen yielded positive results in 23 (53.5 p. cent) cases. Amongst 30 cases with HPV ...

journal_title：Annales de biologie clinique

authors： Luthra UK,Bhatnagar P,Das DK,Sharma BK,Kashyap V,Khan IU,Singh V,Murthy NS

更新日期：1989-01-01 00:00:00

abstract：:Salivary cortisol was determined with four commercially available immunoassays: one enzyme-immunoassay (Cortisol Biotrol), two fluoro-immunoassays (TDX, Abbott; Stratus, Baxter) and one radioimmunoassay (Coat-A-Count, Behring). In order to improve the sensitivity of these immunoassays, it was necessary to increase sam...

journal_title：Annales de biologie clinique

authors： Nahoul K,Patricot MC,Bressot N,Penes MC,Revol A

更新日期：1996-01-01 00:00:00

abstract：:In this review, after a brief summary of the spermatogenesis process, we present some genetic causes of male infertility at chromosome and gene level, known at present. Even though knowledge has greatly increased, in 15% of cases, we still do not know the infertility mechanism. The genotype-phenotype relationship rema...

journal_title：Annales de biologie clinique

authors： Seifer I,Fellous M,Bignon Y

更新日期：1999-05-01 00:00:00

abstract：:According to the French legislation on medical biology (January 16th, 2010), all biological laboratories must be accredited according to ISO 15189 for at least 50% of their activities before the end of 2016. The extraction of DNA from a sample of interest, whether solid or liquid is one of the critical steps in molecu...

journal_title：Annales de biologie clinique

authors： Harlé A,Lion M,Husson M,Dubois C,Merlin JL

更新日期：2013-09-01 00:00:00

abstract：:Patients with renal insufficiency who are hemodialyzed 3 times a week either through a cuprophane membrane or through a polyacrylonitrile (PAN) membrane have the same transcortin and cortisol levels as patients with renal insufficiency who are not dialyzed. Moreover, hemodialysis did not influence acutely the latter t...

journal_title：Annales de biologie clinique

authors： De Moor P,Faict D,Verberckmoes R

更新日期：1985-01-01 00:00:00

abstract：:Red cell ferritin is a residue of erythroblast ferritin. It reflects the balance between the iron supply to the erythroid marrow and the need for haemoglobin synthesis. Erythrocyte ferritin can be measured in haemolysates after discarding plasma and leucocytes by different methods. The decrease in erythrocyte ferritin...

journal_title：Annales de biologie clinique

authors： Guillemin C,Revenant MC,Vernet M,Dezier JF,Charlier C,Paris M,Pressac M

更新日期：1993-01-01 00:00:00

abstract：:The analyzers have been defined as follows: the analyzers are multiparametric (at least 5 parameters available simultaneously), selective, operating patient by patient, list price on May 1, 1984 below 1,000,000 francs, and distributed in France after January 1, 1981. This definition applies in particular to systems al...

journal_title：Annales de biologie clinique

authors： Grafmeyer D,Vassault A,Feuillu A,Naudin C

更新日期：1985-01-01 00:00:00

abstract：:The hospital environment is a potential source of microbial contamination. Thus, the magazines in hospital's waiting rooms are handled by patients and visitors whose health and hygiene conditions can vary widely. In this context, we had measured the microbial load on the surface of magazines. Fifteen magazines from 5 ...

journal_title：Annales de biologie clinique

authors： Adé M,Burger S,Cuntzmann A,Exinger J,Meunier O

更新日期：2017-12-01 00:00:00

abstract：:The experience of a specialized laboratory for the biological diagnosis of inborn errors of metabolism in selected pediatrics patients is reported. The strategy starts with a wide testing of blood and urine, as many inborn errors of metabolism can be detected through testing of blood and urine for increased concentrat...

journal_title：Annales de biologie clinique

authors： Divry P,Maire I,Mathieu M

更新日期：1988-01-01 00:00:00

abstract：:The measurement of CDT (Carbohydrate Deficient Transferrin) is an essential biological tool in the diagnosis and follow-up of alcohol abuse. It is also employed as a marker of abstinence for the restitution of driving licences. However, the precision of measurement, and the between laboratory homogeneity of the result...

journal_title：Annales de biologie clinique

authors： Boehrer JL,Cano Y,Capolaghi B,Desch G,Dosbaa I,Estepa L,Hennache B,Schellenberg F

更新日期：2007-03-01 00:00:00

abstract：:Advances in molecular biology applied to the location of genes have generated a real evolution for the screening of women carrying X-related diseases. It is however imperative to first try to define the status of these women using classical methods: bayesian calculations taking into account genealogical data and direc...

journal_title：Annales de biologie clinique

authors： Kaplan J

更新日期：1988-01-01 00:00:00

abstract：:Recently, homocysteine and new inflamatory biomarkers are demonstrated to be involved in cardiovascular diseases. These risk factors are not well studied in acute coronary syndrome. We investigated the distribution of homocysteine and inflammatory markers in patients with acute coronary syndrome and evaluated the asso...

journal_title：Annales de biologie clinique

authors： El Oudi M,Bouguerra C,Aouni Z,Mazigh C,Bellaaj R,Machghoul S

更新日期：2011-03-01 00:00:00

abstract：:This paper describes the assessment of the homogeneity and stability of a purified and lyophilized human thyroglobulin (Tg), and characterizes its immunoreactivity. The purified and lyophilized Tg is intended to be used as a primary reference material to establish calibration of working serum based reference material....

journal_title：Annales de biologie clinique

authors： Feldt-Rasmussen U,Profilis C,Colinet E,Black E,Bornet H,Bourdoux P,Carayon P,Ericsson UB,Koutras DA,Lamas de Leon L,DeNayer P,Pacini F,Palumbo G,Santos A,Schlumberger M,Seidel C,Van Herle AJ,De Vijlder JJ

更新日期：1996-01-01 00:00:00

abstract：:Microsomal epoxide hydrolase (EC 3.3.2.3. ; formerly EC 4.2.1.63) catalyse the hydration of epoxides into trans dihydro-diols, easily excretable hydrophil compounds. It is an enzyme with very wide specificity for monosubstituted oxiranes, or cis disubstituted oxiranes. It is inactive on polysubstituted epoxides. The h...

journal_title：Annales de biologie clinique

authors： Dansette PM

更新日期：1980-01-01 00:00:00

abstract：:Haemochromatosis is the most common genetic disease in individuals of Northern European origin. This disorder of iron metabolism, for which the molecular basis remains poorly understood, is characterized by an excessive absorption of dietary iron through the duodenal mucosa. Progressive iron loading of parenchymal org...

journal_title：Annales de biologie clinique

authors： Jouanolle AM,David V,Le Gall JY

更新日期：1997-05-01 00:00:00