Histocompatibility antigens in Parkinson's disease.

abstract：OBJECTIVES:Dopamine neurotransmission is a critical factor for executive function, which is controlled by the prefrontal cortex in humans. Although the contribution of genetic factors to the regulation of brain dopaminergic activity is widely acknowledged, identification of a genotype-phenotype association has not yet ...

journal_title：Acta neurologica Scandinavica

authors： Mitaki S,Isomura M,Maniwa K,Yamasaki M,Nagai A,Nabika T,Yamaguchi S

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:The Flt3 ligand (FL) is a cytokine with a neurotrophic and antiapoptotic activity in the central nervous system that induces the survival of neurons. The aim of the study was to measure levels of FL in amyotrophic lateral sclerosis (ALS) patients. MATERIALS AND METHODS:The study involved 23 ALS patients and...

journal_title：Acta neurologica Scandinavica

authors： Iłzecka J

更新日期：2006-09-01 00:00:00

abstract：:We present clinical and virological data on 9 patients, 7 women and 2 men aged 31-56 years, with recurrent aseptic meningitis (Mollaret's meningitis). Polymerase chain reaction detected Herpes simplex virus type 2 DNA in cerebrospinal fluid samples from all patients collected during their latest attacks of meningitis....

journal_title：Acta neurologica Scandinavica

authors： Jensenius M,Myrvang B,Størvold G,Bucher A,Hellum KB,Bruu AL

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVES:A highly adaptive aspect of human memory is the enhancement of explicit, consciously accessible memory by emotional stimuli. We studied the performance of Alzheimer's disease (AD) patients and elderly controls using a memory battery with emotional content, and we correlated these results with the amygdala an...

journal_title：Acta neurologica Scandinavica

authors： Schultz RR,de Castro CC,Bertolucci PH

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disorder of the central nervous system (CNS). Interleukin (IL)-6 and IL-17A may play important roles in the pathogenesis of this disease. High-mobility group box protein 1 (HMGB1), a small but highly conserved ubiquitous protein, is rec...

journal_title：Acta neurologica Scandinavica

authors： Ai P,Zhang X,Xie Z,Liu G,Liu X,Pan S,Wang H

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Satisfactory anabolic reactions, including the activation of the hypothalamic-pituitary-adrenal (HPA) axis, are essential following severe traumatic brain injury (TBI) and aneurysmal subarachnoid hemorrhage (SAH). Many factors may influence this activation. This study aimed to investigate whether individuals ...

journal_title：Acta neurologica Scandinavica

authors： Sörbo A,Eiving I,Theodorsson E,Rydenhag B,Jonsdottir IH

更新日期：2020-04-01 00:00:00

abstract：:Twenty-four male patients, all homosexual except one, with asymptomatic HIV-infection were studied. The patients had no signs of opportunistic CNS-infections but 6 had been treated for syphilis. The patients were tested with auditory brainstem response (ABR) audiometry and with oculomotor tests (saccades and smooth pu...

journal_title：Acta neurologica Scandinavica

authors： Rosenhall U,Håkansson C,Löwhagen GB,Hanner P,Jonsson-Ehk B

更新日期：1989-02-01 00:00:00

abstract：:We assessed cognitive performance and its relationship with clinical and anatomic disease severity in MS with mild to moderate handicap; 34 definite MS and 18 healthy subjects matched for age and education were submitted to a neuropsychological test battery. Both groups were examined for anxiety. MS patients underwent...

journal_title：Acta neurologica Scandinavica

authors： Maurelli M,Marchioni E,Cerretano R,Bosone D,Bergamaschi R,Citterio A,Martelli A,Sibilla L,Savoldi F

更新日期：1992-08-01 00:00:00

abstract：:Neuropsychiatric symptoms such as delusions and misidentifications have been reported in dementia ranging from 10% to 73% in Alzheimer's disease (AD) patients and up to 40% in multi-infarct dementia (MID) patients. The aim of this study was to investigate in 61 AD and 31 MID patients both the frequency and the content...

journal_title：Acta neurologica Scandinavica

authors： Binetti G,Bianchetti A,Padovani A,Lenzi G,De Leo D,Trabucchi M

更新日期：1993-07-01 00:00:00

abstract：:The pulsatility index (PI) registered by the transcranial doppler (TCD) was examined in relation to arterial pCO2 (paCO2) and epidural pressure (ICP). In 10 normal subjects PI was studied during variations in paCO2. In 10 neurosurgical patients with head injuries concomitant measurements of PI and ICP were obtained. T...

journal_title：Acta neurologica Scandinavica

authors： Homburg AM,Jakobsen M,Enevoldsen E

更新日期：1993-06-01 00:00:00

abstract：:Three patients with well-defined clinical and radiographic lesions have been studied with somatosensory evoked potentials (SSEPs). The data indicate that the primary scalp potentials from stimulation of both the arm and leg (N20 and P40) can be lost with thalamic lesions and would be consistent with these potentials b...

journal_title：Acta neurologica Scandinavica

authors： Fisher MA,Perlik SJ

更新日期：1985-01-01 00:00:00

abstract：:The risk of stroke related to asymptomatic carotid artery stenosis is known to be increased in high-grade or rapidly progressive stenosis. Information of the prevalence in the general population is required for the recommendation of screening methods to detect patients needing prophylactic treatment. We studied the pr...

journal_title：Acta neurologica Scandinavica

authors： Harer C,Gusev EI

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVES:To study if type-2 (non-insulin-dependent) diabetes mellitus (NIDDM) is associated with cognitive dysfunction independently of clinically diagnosed dementia in an elderly population. MATERIAL AND METHODS:Cognitive function was investigated with a brief neuropsychological test battery in a non-demented elder...

journal_title：Acta neurologica Scandinavica

authors： Vanhanen M,Kuusisto J,Koivisto K,Mykkänen L,Helkala EL,Hänninen T,Riekkinen P Sr,Soininen H,Laakso M

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:The Danish National Patient Register, Landspatientregistret (LPR), is a register of all hospital discharges and outpatient treatments in Denmark. AIMS:It is increasingly used in research so it is important to understand to what extent this can be used as an accurate source of information. Virtually all pati...

journal_title：Acta neurologica Scandinavica

authors： Mason K,Thygesen LC,Stenager E,Brønnum-Hansen H,Koch-Henriksen N

更新日期：2012-03-01 00:00:00

abstract：:We describe the incidence and explore the quality of registered diagnosis for Guillain-Barré syndrome (GBS) in a population-based retrospective study in South-West Stockholm (SWS), Sweden, during the period 1973-1991. We used data on registered hospital discharges and open-care visits, and from medical records. Medica...

journal_title：Acta neurologica Scandinavica

authors： Jiang GX,de Pedro-Cuesta J,Fredrikson S

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Both pregnancy and high vitamin D concentration seem to generate a protective environment against multiple sclerosis (MS) relapses. Longitudinal case-control analysis of vitamin D concentrations during pregnancy and lactation of MS mothers is lacking. AIMS OF THE STUDY:To examine serum 25-hydroxyvitamin-D3 ...

journal_title：Acta neurologica Scandinavica

authors： Jalkanen A,Kauko T,Turpeinen U,Hämäläinen E,Airas L

更新日期：2015-01-01 00:00:00

abstract：:We present 2 sibs with autosomal recessive spastic paraparesis and severe amyotrophy of the distal limb muscles. Elaborate neurophysiologic studies disclosed slight to moderate slowing of motor conduction, moderate to severe reduction of motor action potentials, denervation potentials, and increased distal motor laten...

journal_title：Acta neurologica Scandinavica

authors： Bruyn RP,Scheltens P,Lycklama à Nijeholt J,de Jong JM

更新日期：1993-06-01 00:00:00

abstract：:Peripheral blood lymphocytes from 23 out of 27 (85%) patients with multiple sclerosis responded to MS brain homogenates by increased formation of active E-rosettes. Lymphocytes from only six out of 78 (8%) patients with other neurological diseases responded to MS brain homogenates. The possible value of the test in th...

journal_title：Acta neurologica Scandinavica

authors： Offner H,Fog T,Rastogi SC,Konat G,Clausen J

更新日期：1979-03-01 00:00:00

abstract：:Regional blood flow in the spinal cord was measured in rabbits, cats and monkeys with radioactively labelled microspheres. The reproducibility of the method was tested in rabbits by 3 consecutive determinations with differently labelled microspheres within the different cord regions, and was found to be good. In all 3...

journal_title：Acta neurologica Scandinavica

authors： Nyström B,Stjernschantz J,Smedegård G

更新日期：1984-10-01 00:00:00

abstract：:The role of metabolic abnormalities in the development of diabetic neuropathy is controversial. To investigate the peripheral nerve function and the influence of hyperglycemia on nerve conduction in insulin-dependent diabetes, a one-year neurophysiological study was carried out in 30 type 1 diabetic patients ranging i...

journal_title：Acta neurologica Scandinavica

authors： Meli F,Cardella F,Raimondo D,Modica A,Muscarella A,Fierro B

更新日期：1989-11-01 00:00:00

abstract：:While the association of spinal cord tumor and high-pressure hydrocephalus is well known, only 5 cases of spinal cord tumor associated with normotensive hydrocephalus have been reported. Two further cases are described here, discussing the possible pathophysiological mechanism. It is suggested that these patients go t...

journal_title：Acta neurologica Scandinavica

authors： Yarnitsky D,Honigman S,Hemli JA,Bental E

更新日期：1987-10-01 00:00:00

abstract：:Supernatants of peripheral blood lymphocytes (PBL), containing lymphokines, isolated from MS patients and healthy subjects were tested for demyelinating activity in organotypic culture of the rat cerebellum. PBL were isolated on Ficoll-paque gradient and cultures in RPMI 1640 medium for 72 h with or without phytohemag...

journal_title：Acta neurologica Scandinavica

authors： Selmaj K,Renkawek K,Alam R,Kida E,Maszewska M,Rozniecki J

更新日期：1986-09-01 00:00:00

abstract：:This study concerns the distribution of T-cell subsets as determined by specific monoclonal antibodies in 50 individuals with complex partial seizures (31) and primary generalized tonic-clonic seizures (19), and in 30 healthy controls. The epileptic group had significantly fewer circulating T4 "helper" lymphocytes and...

journal_title：Acta neurologica Scandinavica

authors： Eeg-Olofsson O,Prchal JF,Andermann F

更新日期：1985-08-01 00:00:00

abstract：:Two cases of adrenoleukodystrophy are described. The pathological picture was consistent with earlier observations about the disease with the difference that the brain tissue revealed material which stained metachromatically with toluidine blue and was insoluble in fat solvents. ...

journal_title：Acta neurologica Scandinavica

authors： Hormia M

更新日期：1978-08-01 00:00:00

abstract：OBJECTIVES:Multiple sclerosis (MS) patients suffer from high levels of anxiety. However, it is unclear which factors are related to anxiety, since study results are inconsistent, and the associated factors have not been examined comprehensively. In this study, we investigated the demographic, disease-related and psycho...

journal_title：Acta neurologica Scandinavica

authors： Wallis O,Bol Y,Köhler S,van Heugten C

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:The importance of health-related quality of life (HRQoL) in multiple sclerosis (MS) is widely acknowledged. In 2015, a multicenter study was launched to assess the HRQoL and coping styles of chronically ill persons in Germany. The aims of this paper were (i) to describe how persons affected by MS assess thei...

journal_title：Acta neurologica Scandinavica

authors： Nickel S,von dem Knesebeck O,Kofahl C

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To investigate whether the cardiac R-R interval variation (RRIV) is of value in differentiating patients with Parkinson's disease (PD) from multiple system atrophy (MSA). BACKGROUND:RRIV assessment is a simple procedure, reflecting mainly vagal efferent activity. Reduced RRIV was reported in MSA. METHODS:RR...

journal_title：Acta neurologica Scandinavica

authors： Gurevich TY,Groozman GB,Giladi N,Drory VE,Hausdorff JM,Korczyn AD

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVES:Until now, the significance of plasma exchange (PE) as a treatment for steroid-unresponsive optic neuritis (ON) is still unclear because placebo-controlled and larger studies are missing. We report our experience with 23 patients treated by PE due to steroid-unresponsive ON. MATERIALS AND METHODS:Patients w...

journal_title：Acta neurologica Scandinavica

authors： Roesner S,Appel R,Gbadamosi J,Martin R,Heesen C

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:Cerebral hypoperfusion has been evidenced in patients with periventricular white matter lucency (PWML), however, our knowledge is limited regarding vasoreactivity (VR) changes in these patients. Therefore, we compared the cerebral blood flow velocity (CBFV) responses during different vasoregulatory challenge...

journal_title：Acta neurologica Scandinavica

authors： Bönöczk P,Panczel G,Nagy Z

更新日期：2004-10-01 00:00:00

abstract：:The cerebrovascular response to arterial hypoxia was studied during blockade of the vascular dopamine receptors and during alpha-adrenergic receptor stimulation and blockade in anaesthetized dogs. Dopamine receptor blockade with pimozide or haloperidol invariably decreased the degree of hypoxic vasodilatation in the ...

journal_title：Acta neurologica Scandinavica

authors： Ekström-Jodal B,Elfverson J,von Essen C

更新日期：1978-02-01 00:00:00