Conduction velocity study in type 1 diabetic patients.

Abstract:

:The role of metabolic abnormalities in the development of diabetic neuropathy is controversial. To investigate the peripheral nerve function and the influence of hyperglycemia on nerve conduction in insulin-dependent diabetes, a one-year neurophysiological study was carried out in 30 type 1 diabetic patients ranging in age from 2-16 years. During the 12-month follow-up period the glycosylated hemoglobin determination, motor conduction velocity of the peroneal nerve and the motor and sensory conduction of the tibial nerve were assessed 3 times, at the beginning of the study and every 6 months thereafter. The sensory latency was found significantly delayed in these patients as compared with the controls. The degree of sensory conduction slowing correlated well with the glycosylated hemoglobin concentrations and improved with the reduction in hyperglycemia.

journal_name

Acta Neurol Scand

authors

Meli F,Cardella F,Raimondo D,Modica A,Muscarella A,Fierro B

doi

10.1111/j.1600-0404.1989.tb03905.x

subject

Has Abstract

pub_date

1989-11-01 00:00:00

pages

432-7

issue

5

eissn

0001-6314

issn

1600-0404

journal_volume

80

pub_type

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