Neuropsychological assessment in MS: clinical, neurophysiological and neuroradiological relationships.

abstract：OBJECTIVES:To evaluate the activity of cortico-cortical (intracortical) inhibitory circuits within the motor cortex in patients with progressive asymmetric limb-kinetic apraxia. MATERIALS AND METHODS:We studied 4 patients with progressive limb-kinetic apraxia whose clinical diagnosis was corticobasal degeneration (CBD...

journal_title：Acta neurologica Scandinavica

authors： Okuma Y,Urabe T,Mochizuki H,Miwa H,Shimo Y,Mori H,Mizuno Y

更新日期：2000-10-01 00:00:00

abstract：:The present communication is devoted to investigating the possibility that in myotonic dystrophy (MyD) a decreased ATP utilization by the membrane may produce modifications in glycoprotein structure and/or in the supramolecular arrangement of some membrane proteins. The study was carried out a) by determining the memb...

journal_title：Acta neurologica Scandinavica

authors： Sandrini G,Bottiroli G,Nappi G,Balduini C,Brovelli A

更新日期：1982-06-01 00:00:00

abstract：:Patients with prior poliomyelitis with paresis and excessive use (n = 8) and low use (n = 6) of residual anterior tibial motor units (MUs) during walking were subjected to muscle biopsy of the anterior tibial muscle (TA). Antibodies directed against cytoskeletal proteins, spectrin and desmin, and against Leu-19, a myo...

journal_title：Acta neurologica Scandinavica

authors： Borg K,Edström L

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVES:Vascular endothelial growth factor (VEGF) acts in angiogenesis and neuroprotection, although the beneficial effects on experimental ischemic stroke (IS) have not been replicated in clinical studies. We investigated serum VEGF (s-VEGF) in the acute stage (baseline) and 3 months post-stroke in relation to stro...

journal_title：Acta neurologica Scandinavica

authors： Åberg ND,Wall A,Anger O,Jood K,Andreasson U,Blennow K,Zetterberg H,Isgaard J,Jern C,Svensson J

更新日期：2020-05-01 00:00:00

abstract：:A patient with paraneoplastic encephalomyelitis (PEM) and small cell lung cancer had a clinical presentation of acute polyneuritis. The patient had an antibody (anti-Hu) restricted to nuclei of neurons identical to that reported in patients with subacute sensory neuronopathy and lung cancer. This finding further suppo...

journal_title：Acta neurologica Scandinavica

authors： Graus F,Elkon KB,Lloberes P,Ribalta T,Torres A,Ussetti P,Valls J,Obach J,Agusti-Vidal A

更新日期：1987-04-01 00:00:00

abstract：:The cerebrospinal fluid (CSF) findings of 16 patients with mycoplasma pneumoniae infections and different neurologic complications are presented. In acute meningitis there was predominantly a mononuclear cell reaction remitting in accordance with the improvement of the clinical symptoms. An early switch from IgM to Ig...

journal_title：Acta neurologica Scandinavica

authors： Maida E,Kristoferitsch W

更新日期：1982-05-01 00:00:00

abstract：:Examinations with directional Doppler (DD) with 10 MHz transducer, and pulsed Doppler in combination with two-dimensional sector scanner with 3 MHz transducer (Duplex) were carried out on 100 vessels in 51 patients with transitory ischemic attacks (TIA) and minor stroke within the territory of the internal carotid art...

journal_title：Acta neurologica Scandinavica

authors： Zbornikova V,Akesson JA,Lassvik C

更新日期：1982-04-01 00:00:00

abstract：OBJECTIVES:Epilepsia partialis continua (Kojewnikow's syndrome) can be classified into 2 groups. The 1st group had stable neurological deficit, and the 2nd group had slowly progressive neurological deficit. The latter usually manifests not tetraplegia, but hemiplegia. We describe 3 patients with epilepsia partialis con...

journal_title：Acta neurologica Scandinavica

authors： Takahashi Y,Kubota H,Fujiwara T,Yagi K,Seino M

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVES:To study the changes in the burden of informal caregivers of patients with disorders of consciousness (DOC) over time. MATERIALS AND METHODS:Short Form-12, Family Strain Questionnaire, Beck Depression Inventory and Coping Orientations to Problem Experiences were administered. RESULTS:Data collected on 216 ...

journal_title：Acta neurologica Scandinavica

authors： Covelli V,Sattin D,Giovannetti AM,Scaratti C,Willems M,Leonardi M

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:Alzheimer's disease assessment scale-cognitive subscale (ADAS-Cog) has become a standard clinical trials outcome for cognition, but has been recognized as deficient in areas including coverage of cognitive domains, sensitivity and standardization. Computerized test batteries may address some of these issues....

journal_title：Acta neurologica Scandinavica

authors： Wesnes K,Edgar C,Andreasen N,Annas P,Basun H,Lannfelt L,Zetterberg H,Blennow K,Minthon L

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Delayed-release dimethyl fumarate (DMF) treatment can be associated with reduced lymphocyte and leucocyte counts, which might persist after DMF discontinuation. CASE PRESENTATION:We report the case of a patient with severe disease reactivation despite prolonged lymphopenia after DMF discontinuation. We desc...

journal_title：Acta neurologica Scandinavica

authors： Zecca C,Antozzi CG,Torri Clerici V,Ferrazzini M,Mantegazza RE,Rossi S,Gobbi C

更新日期：2018-06-01 00:00:00

abstract：:For patients with Parkinson's disease (PD), excessive daytime sleepiness (PD-EDS) is a debilitating non-motor symptom and may be affected by mood symptoms, especially depression and anxiety. Few neuroimaging works have attempted to identify the neural features of PD-EDS, but various findings were reported. The purpose...

journal_title：Acta neurologica Scandinavica

authors： Wen MC,Chan LL,Tan LCS,Tan EK

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:Patients with multiple sclerosis were reported to harbour antibodies not only against proteins and glycoproteins but also against glycolipids, including sulfatide and galactosylceramide (GalCer), the two major glycosphingolipids of myelin. However, previous results were inconsistent concerning glycosphingoli...

journal_title：Acta neurologica Scandinavica

authors： Haghighi S,Lekman A,Nilsson S,Blomqvist M,Andersen O

更新日期：2012-01-01 00:00:00

abstract：:Three Alzheimer's disease patients with Pisa syndrome were presented. These patients were treated with cholinesterase inhibitors within a post-marketing surveillance study. The clinical and pharmacological histories of these patients suggest a relation between cholinesterase inhibitors and the pleurothotonus. The diff...

journal_title：Acta neurologica Scandinavica

authors： Vanacore N,Suzzareddu G,Maggini M,Casula A,Capelli P,Raschetti R

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid artery disease (CAD) is able to critically impair cerebral autoregulation which increases the risk for stroke. As therapeutic strategy largely depends on the degree of CAD, we investigated whether this gradation is also related to significant changes in autoregulatory capacity. We applied...

journal_title：Acta neurologica Scandinavica

authors： Haubrich C,Klemm A,Diehl RR,Möller-Hartmann W,Klötzsch C

更新日期：2004-03-01 00:00:00

abstract：:Lymphocyte transformation responses to measles, mumps, herpes simplex and parainfluenza virus antigens and purified protein derivative of tuberculin were determined in both 78 normal controls and 40 patients with multiple sclerosis, 16 of whom were studied serially. Patients with multiple sclerosis showed significantl...

journal_title：Acta neurologica Scandinavica

authors： Sagar HJ,Allonby ID,Hughes P

更新日期：1981-02-01 00:00:00

abstract：OBJECTIVES:A previous epidemiological study of Parkinson's disease (PD) in the county of Tartu, Estonia, found an adjusted prevalence rate of 152/100 000 persons. We aimed to determine PD prevalence almost 20 years later, as well as evaluate any dynamic changes in disease frequency compared to the first study. METHODS...

journal_title：Acta neurologica Scandinavica

authors： Kadastik-Eerme L,Taba N,Asser T,Taba P

更新日期：2018-09-01 00:00:00

abstract：:The prevalence of probable multiple sclerosis (MS) in Caltanissetta city, Sicily, is at least 51 per 100,000. If possible multiple sclerosis patients are included, it is 54 per 100,000. This value is similar to that found in other cities in Sicily: Enna, Monreale and Agrigento. The high prevalence of multiple sclerosi...

journal_title：Acta neurologica Scandinavica

authors： Savettieri G,Elian M,Giordano D,Grimaldi G,Ventura A,Dean G

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVES:To estimate the total costs of multiple sclerosis (MS) for all Canadians in 1994. METHODS:Prevalence-based study estimating disease-related societal costs for Canadians with MS in 1994. The human capital approach was used to estimate the value of lost productivity due to illness. Two components were reveale...

journal_title：Acta neurologica Scandinavica

authors： Asche CV,Ho E,Chan B,Coyte PC

更新日期：1997-05-01 00:00:00

abstract：:Multiple sclerosis (MS) is associated with autoimmune disorders (AIDs) in individual patients, and limited data suggest a possible familial association of MS and AIDs; however, no systematic study has been conducted on the occurrence of AIDs in the families of MS patients. Using a standardized interview focused on AID...

journal_title：Acta neurologica Scandinavica

authors： Heinzlef O,Alamowitch S,Sazdovitch V,Chillet P,Joutel A,Tournier-Lasserve E,Roullet E

更新日期：2000-01-01 00:00:00

abstract：:The aim of this paper was to evaluate the outcome and the factors predictive for a good prognosis of resective surgery for intractable partial epilepsy guided by subdural electrode arrays (SEA's) and operative electrocorticography. Sixty-four patients, aged 8-52 years, were evaluated with chronic SEAs in order to reco...

journal_title：Acta neurologica Scandinavica

authors： Jennum P,Dhuna A,Davies K,Fiol M,Maxwell R

更新日期：1993-06-01 00:00:00

abstract：:Epileptic seizures are refractory to treatment in approximately one-third of patients despite the recent introduction of many newer antiepileptic drugs (AEDs). Development of novel AEDs therefore remains a high priority. Perampanel is a first-in-class non-competitive selective AMPA receptor antagonist with a unique me...

journal_title：Acta neurologica Scandinavica

authors： Tsai JJ,Wu T,Leung H,Desudchit T,Tiamkao S,Lim KS,Dash A

更新日期：2018-04-01 00:00:00

abstract：:The role of the ophthalmic artery (OA) as a collateral to the cerebral circulation in carotid occlusive disease is somewhat controversial. The aim of this study was to assess the importance of this collateral by comparing the results of transorbital Doppler ultrasonography and regional cerebral blood flow measurements...

journal_title：Acta neurologica Scandinavica

authors： Kerty E,Nyberg-Hansen R,Dahl A,Bakke SJ,Russell D,Rootwelt K

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that status epilepticus can lead to neuronal injury. However, the effect of a small number of isolated seizures is uncertain. METHODS:We used structural MRI and neuropathology to study the effects of isolated seizures induced by kainic acid (KA), (RS)-2-amino-3-(3-hydroxy-5-tert-...

journal_title：Acta neurologica Scandinavica

authors： Acosta MT,Munashinge J,Zhang L,Guerron DA,Vortmeyer A,Theodore WH

更新日期：2012-01-01 00:00:00

abstract：:Single, small (less than 1 cm) enhancing lesions are frequent findings on CT scans of Indian patients with seizures. These lesions have also been reported in patients from other parts of the world. They often resolve spontaneously and their etiology has been disputed for over a decade. Initially diagnosed in Indian pa...

journal_title：Acta neurologica Scandinavica

authors： Rajshekhar V

更新日期：1991-12-01 00:00:00

abstract：:The phosphomannosyl receptor system is responsible for both the receptor-mediated endocytosis and the intracellular transport of lysosomal enzymes. In the present study this receptor system was examined in affected muscles of patients with various neuromuscular diseases. The total activity of beta-N-acetyl-glucosamini...

journal_title：Acta neurologica Scandinavica

authors： Salminen A,Marjomäki V,Tolonen U,Myllylä VV

更新日期：1988-06-01 00:00:00

abstract：OBJECTIVES:To examine the mechanisms of alternative strategies developed by stroke patients to compensate their motor impairment and their role in recovery. MATERIAL AND METHODS:The three-dimensional kinematics of the upper limb were quantified during unconstrained reaching movements in seven healthy individuals and i...

journal_title：Acta neurologica Scandinavica

authors： Roby-Brami A,Feydy A,Combeaud M,Biryukova EV,Bussel B,Levin MF

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:White blood cells might have a pathogenetic role in ischemic vascular conditions. Several studies have suggested that increased adhesiveness of these cells could contribute to such a damage. The present study was undertaken in order to examine the adhesive properties of leukocytes in the peripheral blood of p...

journal_title：Acta neurologica Scandinavica

authors： Meiner Z,Arber N,Liberman E,Leibovitz E,Seltzer D,Berliner S

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVE:To describe clinical features of a patient with secretions of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) during an epileptic attack. PATIENT:A 65-year-old woman experienced frequent bouts of polyuria, pyrexia and general fatigue after several years of a cerebral contusion involving ...

journal_title：Acta neurologica Scandinavica

authors： Obi T,Takatsu M,Konishi T,Mizoguchi K,Nishimura Y

更新日期：2002-10-01 00:00:00

abstract：:We studied a Becker muscular dystrophy (BMD) family with a manifesting carrier. Proximal muscle weakness, pseudohypertrophy of the calves, significantly elevated serum creatine kinase and dystrophic alterations in the muscle biopsy were the characteristic phenotypical features of this manifesting carrier. The recombin...

journal_title：Acta neurologica Scandinavica

authors： Ionasescu VV,Searby CC,Ionasescu R

更新日期：1989-06-01 00:00:00