Effects of cross-innervation and disuse on the twitch speed of fast and slow hindlimb muscles in the decerebellate cat.

Abstract:

:In adult cats, we have investigated how nerve cross-union between slow and fast muscle affects twitch contraction and half-relaxation times in the presence and absence of motor disuse, produced by complete decerebellation. Cerebellectomy abolished the slowing of cross-innervated fast muscle and diminished the amount of speeding up of cross-innervated slow muscle. The results are consistent with the idea that cross-innervation between fast and slow muscles affects contraction speed through changes in the patterns of muscle fiber activation.

journal_name

Brain Res

journal_title

Brain research

authors

Eerbeek O,Stenvers JW,de Jong JM

doi

10.1016/0006-8993(82)90480-2

subject

Has Abstract

pub_date

1982-02-18 00:00:00

pages

155-8

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(82)90480-2

journal_volume

234

pub_type

杂志文章
  • Steroid-independent endogenous opioid peptide suppression of pulsatile luteinizing hormone release between estrus and diestrus in the rat estrous cycle.

    abstract::We have previously demonstrated an absence of ovarian steroid negative feedback on pulsatile luteinizing hormone (LH) release between estrus and early diestrus 1 (D1) in the rat estrous cycle. The object of the present study was to determine if there was a steroid-independent endogenous opioid peptide (EOP) suppressio...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)90902-4

    authors: Babu GN,Marco J,Bona-Gallo A,Gallo RV

    更新日期:1987-07-28 00:00:00

  • Gamma-hydroxybutyrate and ethanol depress spontaneous excitatory postsynaptic currents in dopaminergic neurons of the substantia nigra.

    abstract::Gamma-hydroxybutyrate (GHB) has been shown to have therapeutical properties in various psychiatric disorders, especially in alcohol abuse, and to mimic different actions of ethanol at the cellular and system level. Using whole-cell patch-clamp recordings on brain slices of 21- to 25-day-old rats, the present study inv...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2003.10.046

    authors: Brancucci A,Berretta N,Mercuri NB,Francesconi W

    更新日期:2004-01-30 00:00:00

  • Dorsal hindbrain 5-HT3 receptors participate in control of meal size and mediate CCK-induced satiation.

    abstract::We have previously shown that systemic administration of ondansetron, a selective serotonin type-3 (5-HT3) receptor antagonist, attenuates cholecystokinin (CCK)-induced suppression of food intake. The exact location of 5-HT3 receptors mediating this action is not clear and may involve hindbrain 5-HT3 receptors. In thi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.05.058

    authors: Hayes MR,Covasa M

    更新日期:2006-08-04 00:00:00

  • Glycan changes in the olfactory mucosa of rats with experimental autoimmune encephalomyelitis.

    abstract::Glycans are components of glycoconjugates and function in odorant recognition and cell signaling in the olfactory mucosa. However, little is known about glycan expression in the olfactory mucosa in the presence of neuroinflammatory disorders, which can influence olfaction. We evaluated the changes in glycan in the olf...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2020.146649

    authors: Park C,Kim J,Ahn M,Choi Y,Shin T

    更新日期:2020-04-01 00:00:00

  • Presence of synapsin I in afferent and efferent nerve endings of vestibular sensory epithelia.

    abstract::The presence and localization of synapsin I were investigated in the cat vestibular epithelium, using a rabbit anti-synapsin I antibody. The staining was performed by immunofluorescence or by a peroxidase-anti-peroxidase technique. A strong immunoreactivity was observed with both methods. It appeared as spherical patc...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)91176-5

    authors: Favre D,Scarfone E,Di Gioia G,De Camilli P,Dememes D

    更新日期:1986-10-08 00:00:00

  • Regional preferences of AMPA receptor modulators determined through agonist binding autoradiography.

    abstract::Autoradiographic techniques were used to test if positive modulators of AMPA-type glutamate receptors have regionally differentiated effects on ligand binding. Cyclothiazide, a drug with ten fold greater effects on 'flip' than 'flop' splice variants of the receptors, had unequal effects across the subdivisions of hipp...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)01315-2

    authors: Kessler M,Mutneja MS,Rogers G,Lynch G

    更新日期:1998-02-02 00:00:00

  • Colchicine-induced alterations in receptor-stimulated phosphoinositide hydrolysis in the rat hippocampus.

    abstract::Intradentate administration of colchicine has been reported to affect the cholinergic muscarinic system in the hippocampus, causing a reduction in quinclidinylbenzilate binding sites and an increase in choline acetyltransferase activity. Since the cholinergic muscarinic system is coupled to the formation of inositolph...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)91419-4

    authors: Tandon P,Harry GJ,Tilson HA

    更新日期:1989-01-16 00:00:00

  • Dexmedetomidine attenuated early brain injury in rats with subarachnoid haemorrhage by suppressing the inflammatory response: The TLR4/NF-κB pathway and the NLRP3 inflammasome may be involved in the mechanism.

    abstract::Early brain injury (EBI) plays a pivotal role in the prognosis of patients with subarachnoid haemorrhage (SAH). Dexmedetomidine (DEX), a highly selective α2 receptor agonist, is reported to exert multiple protective effects in many neurological diseases. This study was designed to investigate whether DEX had neuroprot...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2018.05.040

    authors: Yin D,Zhou S,Xu X,Gao W,Li F,Ma Y,Sun D,Wu Y,Guo Q,Liu H,Han L,Wang Z,Wang Y,Zhang J

    更新日期:2018-11-01 00:00:00

  • Amino acid release from biopsy samples of temporal neocortex from patients with Alzheimer's disease.

    abstract::Tissue prisms prepared from neurosurgical samples of temporal neocortex of Alzheimer and control patients, upon depolarization preferentially released aspartate, glutamate and gamma-aminobutyrate (GABA). The Alzheimer and control samples did not significantly differ in the pattern of amino acid release, although acety...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)91131-9

    authors: Smith CC,Bowen DM,Sims NR,Neary D,Davison AN

    更新日期:1983-03-28 00:00:00

  • Sensitivity to seizure-like activity in Drosophila following acute hypoxia and hypercapnia.

    abstract::Human seizure disorders represent a heterogeneous collection of neuropathies, many of which are poorly understood. To investigate the etiology of seizure disorders, we have used a group of Drosophila mutants known as the bang-sensitive (BS) paralytics. The BS mutants exhibit seizure-like activity (SLA) following a wid...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2009.12.036

    authors: Whelan J,Burke B,Rice A,Tong M,Kuebler D

    更新日期:2010-02-26 00:00:00

  • A pharmacogenetic evaluation of the role of local anesthetic actions in the cocaine kindling process.

    abstract::Repeated administration of subconvulsant doses of lidocaine or cocaine results in the development of an increased susceptibility to seizures induced by the two drugs (pharmacological kindling). It has been hypothesized that the local anesthetic properties of cocaine are responsible for its convulsant and epileptogenic...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)90628-9

    authors: Marley RJ,Witkin JM,Goldberg SR

    更新日期:1991-10-25 00:00:00

  • Tau immunoreactivity associated with aluminum maltolate-induced neurofibrillary degeneration in rabbits.

    abstract::Intracisternal administration of aluminum maltolate to rabbits produces a marked argyrophilic neurofibrillary degeneration (NFD) which is also immunoreactive for both phosphorylated and non-phosphorylated microtubule associated protein tau. Using tissue fixation in PBF, the monoclonal antibodies Tau-2 and AT8 stain th...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)01297-u

    authors: Savory J,Huang Y,Herman MM,Reyes MR,Wills MR

    更新日期:1995-01-16 00:00:00

  • Estrogen-dependent changes in estrogen receptor-β mRNA expression in middle-aged female rat brain.

    abstract::During aging, estrogen production and circulating levels of estrogen are markedly decreased in females. Although several differences exist in the process of reproductive aging between women and female rats, the results of many studies suggest that the female rat, especially the middle-aged or aged ovariectomized femal...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2013.11.010

    authors: Yamaguchi N,Yuri K

    更新日期:2014-01-16 00:00:00

  • Role of protein phosphatases in the modulation of neuronal membrane currents.

    abstract::Although much is known regarding the modulation of ion channels through protein phosphorylation, little is known about their dephosphorylation by protein phosphatases (PrPs). To address this issue we examined the effects of a phosphatase inhibitor, okadaic acid (OA), and protein phosphatases obtained from rabbit skele...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)90611-x

    authors: Ichinose M,Byrne JH

    更新日期:1991-05-17 00:00:00

  • Failure to down regulate NMDA receptors in the striatum and nucleus accumbens associated with neuroleptic-induced dyskinesia.

    abstract::The syndrome of vacuous chewing movements (VCMs) in rats is similar in many respects to tardive dyskinesia (TD) in humans. Both syndromes are characterized by delayed onset of persistent orofacial dyskinesias in a sub-group of subjects chronically treated with neuroleptics. Using the rat model, we examined the role of...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)00196-6

    authors: Hamid EH,Hyde TM,Baca SM,Egan MF

    更新日期:1998-06-15 00:00:00

  • Demonstration and localization of neuronal degeneration in the rat forebrain following a single exposure to MDMA.

    abstract::Methylenedioxymethamphetamine (MDMA, Ecstasy) is a powerful releaser of serotonin. Increasing recreational use of this stimulant and hallucinogenic drug has raised concerns about its potential to produce brain damage. The vast majority of previous research studies have focused on the compound's ability to deplete sero...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(03)02563-0

    authors: Schmued LC

    更新日期:2003-06-06 00:00:00

  • The effect of ligation combined with section on anterograde axonal transport in rabbit hypoglossal nerve.

    abstract::The axonal transport of radiolabeled slow phase proteins and fast phase glycoproteins was studied in rabbit hypoglossal nerve one week after axotomy. The nerves were ligated and cut to prevent axonal regeneration into the distal stump. In this situation of obstructed axonal outgrowth, the axonal transport of these com...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90953-2

    authors: Frizell M

    更新日期:1982-10-28 00:00:00

  • Time course of changes in the concentrations of amino acids in the brain structures of pentylenetetrazole-kindled rats.

    abstract::The results showed that the development of seizures (pentylenetetrazole, PTZ-induced kindling; PTZ was administered to rats at a subconvulsive dose of 35mg/kg three times a week, i.p.) was accompanied by a progressive recruitment of limbic structures and a characteristic pattern of changes in the brain tissue concentr...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2010.04.045

    authors: Maciejak P,Szyndler J,Turzyńska D,Sobolewska A,Bidziński A,Kołosowska K,Płaźnik A

    更新日期:2010-06-25 00:00:00

  • Impairment of long-term potentiation and paired-pulse facilitation in rat hippocampal dentate gyrus following developmental lead exposure in vivo.

    abstract::Neonatal rats were exposed to lead from parturition to weaning via the milk of dams drinking 0.2% lead acetate solution. The alterations of long-term potentiation (LTP) and paired-pulse facilitation (PPF) of hippocampal dentate gyrus in adult rats (90-115 days) following developmental lead exposure were studied in viv...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)00739-2

    authors: Ruan DY,Chen JT,Zhao C,Xu YZ,Wang M,Zhao WF

    更新日期:1998-09-28 00:00:00

  • Carnosine-like immunoreactivity is associated with synaptic vesicles in photoreceptors of the frog retina.

    abstract::The distribution of carnosine-like immunoreactivity in photoreceptors of the frog retina was studied by post-embedding electron microscope immunocytochemistry. Different fixation and embedding procedures were applied and the best results were achieved on sections from tissue embedded in the hydrophilic resin LR White....

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)90256-9

    authors: Pognetto MS,Cantino D,Fasolo A

    更新日期:1992-04-24 00:00:00

  • An endogenous inhibitory factor for choline acetyltransferase.

    abstract::Chromatography of partially purified choline acetyltransferase (CAT) over carboxymethyl cellulose may result in the loss of up to 95% of the enzyme activity. This loss of activity can be prevented by running the chromatographs at low protein concentration with a large gradient volume suggesting that interactions betwe...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)90552-8

    authors: Cozzari C,Hartman BK

    更新日期:1983-10-03 00:00:00

  • Spinal pain suppression mechanisms may differ for phasic and tonic pain.

    abstract::The dorsolateral funiculus (DLF) spinal pathway has previously been identified as a major pathway involved in descending modulation of pain. While bilateral lesions of the DLF attenuated systemic morphine analgesia as measured by the tail-flick test, they failed to attenuate analgesia as measured by the formalin test....

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90582-7

    authors: Ryan SM,Watkins LR,Mayer DJ,Maier SF

    更新日期:1985-05-13 00:00:00

  • Regional metabolic changes in the pedunculopontine nucleus of unilateral 6-hydroxydopamine Parkinson's model rats.

    abstract::The pedunculopontine nucleus (PPN) located in the mesopontine tegmentum is innervated by descending projections from nuclei in the basal ganglia. The present study was performed to determine whether nigrostriatal dopaminergic neuron degeneration is associated with changes in PPN metabolic activity. Unilateral nigrostr...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)01268-8

    authors: Carlson JD,Pearlstein RD,Buchholz J,Iacono RP,Maeda G

    更新日期:1999-05-15 00:00:00

  • The effects of thalidomide and minocycline on taxol-induced hyperalgesia in rats.

    abstract::Chemotherapy-induced pain is the most common treatment-limiting complication encountered by cancer patients receiving taxane-, vinca alkaloid- or platin-based chemotherapy. Several lines of evidence indicate that activation of pro-inflammatory cascades involving the release of cytokines including tumor necrosis factor...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2008.07.001

    authors: Cata JP,Weng HR,Dougherty PM

    更新日期:2008-09-10 00:00:00

  • Methyl palmoxirate increases eating behavior and brain Fos-like immunoreactivity in rats.

    abstract::Administration of methyl palmoxirate (MP), an inhibitor of fatty acid oxidation, stimulates eating behavior in rats. Fos immunohistochemistry was used to determine neural pathways that may play a role in the eating response to MP. The number of cells showing Fos-like immunoreactivity (Fos-li) was quantified by compute...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)01143-8

    authors: Horn CC,Friedman MI

    更新日期:1998-01-19 00:00:00

  • Transcriptional activity of human brain estrogen receptor-α splice variants: evidence for cell type-specific regulation.

    abstract::Estrogen receptor α (ERα) isoforms with complex types of alternative splicing are naturally present in the human brain and may affect canonical receptor signaling. In the present study we investigated transcriptional activity of common ERα splice variants from this group with different molecular defects: MB1 (intron r...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2012.12.050

    authors: Ishunina TA,Sluiter AA,Swaab DF,Verwer RW

    更新日期:2013-03-15 00:00:00

  • Daily rhythms of cognition-related factors are modified in an experimental model of Alzheimer's disease.

    abstract::The accumulation of amyloid-β (Aβ) peptides in the brain of Alzheimer disease patients is associated to cognitive deficit, increased oxidative stress, and alterations in the circadian rhythms. Brain-derived neurotrophic factor (BDNF) and Neurogranin (RC3), play an important role in the synaptic plasticity underlying m...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2017.01.033

    authors: Navigatore-Fonzo L,Castro A,Pignataro V,Garraza M,Casais M,Anzulovich AC

    更新日期:2017-04-01 00:00:00

  • Muscarinic receptor-dependent activation of phospholipase C in the developing human fetal central nervous system.

    abstract::The coupling of muscarinic-cholinergic receptors (mAChR) to adenylate cyclase and phospholipase C (PLC) second messenger systems has been demonstrated in many animal species. However, little is known about this association in the developing human central nervous system. Because of the proposed role of acetylcholine in...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)90365-4

    authors: Larocca JN,Rodriguez-Gabin AG,Rashbaum WK,Weidenheim KM,Lyman WD

    更新日期:1994-08-08 00:00:00

  • Angiotensin AT1 receptors in the preoptic area negatively modulate the cardiovascular and ACTH responses induced in rats by intrapreoptic injection of prostaglandin E2.

    abstract::We previously reported that brain angiotensin II type 2 (AT2) receptors contribute to the hyperthermia induced by intrahypothalamic (intrapreoptic (i.p.o.)) administration of prostaglandin E2 (PGE2) in rats. The present study was carried out to investigate the role of angiotensin II (ANG II) receptors in the cardiovas...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)02218-0

    authors: Watanabe T,Sakata Y,Wada M

    更新日期:2000-01-03 00:00:00

  • Quantitative autoradiographic studies of dopamine D3 receptors in rat cerebellum using [125I]S(-)5-OH-PIPAT.

    abstract::Recently, [125I]S(-)5-OH-PIPAT (5-hydroxy-2-(N-n-propyl-N-3'-iodo-2'-propenyl)amino-tetralin) was reported to be a selective radioiodinated ligand for dopamine D2-like receptors. This ligand displayed a high binding affinity (Kd = 0.3-0.4 nM) and an agonist binding profile to dopamine D2 and D3 receptors expressed in ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)01014-7

    authors: Vessotskie JM,Kung MP,Chumpradit S,Kung HF

    更新日期:1997-12-05 00:00:00