Detection of a protein of avian leukoviruses in uninfected chick cells by radioimmunoassay.

abstract：:Semlike forest virus capsid protein cosedimented with the large ribosomal subunit at 60S in sucrose gradients after treatment of cytoplasm from infected cells with Triton X-100 and EDTA. In CsCl gradients the capsid protein banded with the subunit at a density of 1.56 to 1.57 g/cm3. Most of the capsid protein could be...

journal_title：Journal of virology

authors： Ulmanen I,Söderlund H,Kääriäinen L

更新日期：1976-10-01 00:00:00

abstract：:Replication of all positive-strand RNA viruses is intimately associated with membranes. Here we utilize electron tomography and other methods to investigate the remodeling of membranes in poliovirus-infected cells. We found that the viral replication structures previously described as "vesicles" are in fact convoluted...

journal_title：Journal of virology

authors： Belov GA,Nair V,Hansen BT,Hoyt FH,Fischer ER,Ehrenfeld E

更新日期：2012-01-01 00:00:00

abstract：:Developing an immunotherapy to keep human immunodeficiency virus type 1 (HIV-1) replication suppressed while discontinuing highly active antiretroviral therapy (HAART) is an important challenge. In the present work, we evaluated in vitro whether dendritic cells (DC) electroporated with gag mRNA can induce HIV-specific...

journal_title：Journal of virology

authors： Van Gulck ER,Vanham G,Heyndrickx L,Coppens S,Vereecken K,Atkinson D,Florence E,Kint I,Berneman ZN,Van Tendeloo V

更新日期：2008-04-01 00:00:00

abstract：:Activation of microglia and astroglia is seen in many neurodegenerative diseases including prion diseases. Activated glial cells produce cytokines as a protective response against certain pathogens and as part of the host inflammatory response to brain damage. In addition, cytokines might also exacerbate tissue damage...

journal_title：Journal of virology

authors： Tribouillard-Tanvier D,Striebel JF,Peterson KE,Chesebro B

更新日期：2009-11-01 00:00:00

abstract：:The innate and adaptive immune responses have evolved distinct strategies for controlling different viral pathogens. Encephalomyocarditis virus (EMCV) is a picornavirus that can cause paralysis, diabetes, and myocarditis within days of infection. The optimal innate immune response against EMCV in vivo requires CD1d. I...

journal_title：Journal of virology

authors： Ilyinskii PO,Wang R,Balk SP,Exley MA

更新日期：2006-07-01 00:00:00

abstract：:In mammalian cells, alphavirus replication complexes are anchored to the plasma membrane. This interaction with lipid bilayers is mediated through the viral methyl/guanylyltransferase nsP1 and reinforced by palmitoylation of cysteine residue(s) in the C-terminal region of this protein. Lipid content of membranes suppo...

journal_title：Journal of virology

authors： Bakhache W,Neyret A,Bernard E,Merits A,Briant L

更新日期：2020-05-04 00:00:00

abstract：:Purified preparations of human adenovirus type 12 showed two bands when subjected to isopycnic centrifugation in a density gradient of cesium chloride. Their density difference was about 0.003 g/ml, suggesting a small difference in their deoxyribonucleic acid to protein ratio. Virions with a lighter density can kill h...

journal_title：Journal of virology

authors： Mak S

更新日期：1971-04-01 00:00:00

abstract：:Borna disease virus (BDV) is a neurotropic virus with a broad host and geographic range. Lewis rats were immunized against BDV with a recombinant vaccinia virus expressing the BDV nucleoprotein and were later infected with BDV to evaluate protection against Borna disease (BD). Relative to animals that were not immuniz...

journal_title：Journal of virology

authors： Lewis AJ,Whitton JL,Hatalski CG,Weissenböck H,Lipkin WI

更新日期：1999-03-01 00:00:00

abstract：:Natural killer (NK) cells are components of the innate immunity and are key players in the defense against virus-infected and malignant cells. NK cells are particularly important in the innate defense against herpesviruses, including alphaherpesviruses. Aggravated and life-threatening alphaherpesvirus-induced disease ...

journal_title：Journal of virology

authors： De Pelsmaeker S,Dierick E,Klupp B,Mettenleiter TC,Cantoni C,Vitale M,Favoreel HW

更新日期：2019-03-21 00:00:00

abstract：:The Epstein-Barr virus (EBV)-determined nuclear antigens EBNA 1, 2, 3, 4, and 6, regularly expressed in EBV-transformed lymphoblastoid cell lines, vary in size among viral strains. We have used this characteristic to trace the spread of the virus within seven families by using an approach called Ebnotyping. Among 33 e...

journal_title：Journal of virology

authors： Gratama JW,Oosterveer MA,Klein G,Ernberg I

更新日期：1990-10-01 00:00:00

abstract：:Human immunodeficiency virus type 1 uses ribosomal frameshifting for translation of the Gag-Pol polyprotein. Frameshift activities are thought to be tightly regulated. Analysis of gag p1 sequences from 270 plasma virions identified in 64% of the samples the occurrence of polymorphism that could lead to changes in ther...

journal_title：Journal of virology

authors： Telenti A,Martinez R,Munoz M,Bleiber G,Greub G,Sanglard D,Peters S

更新日期：2002-08-01 00:00:00

abstract：:Human papillomavirus (HPV) is a strongly conserved DNA virus, high-risk types of which can cause cervical cancer in persistent infections. The most common type found in HPV-attributable cancer is HPV16, which can be subdivided into four lineages (A to D) with different carcinogenic properties. Studies have shown HPV16...

journal_title：Journal of virology

authors： van der Weele P,Meijer CJLM,King AJ

更新日期：2017-09-12 00:00:00

abstract：UNLABELLED:Broadly neutralizing antibodies (bNAbs) specific for conserved epitopes on the HIV-1 envelope (Env) are believed to be essential for protection against multiple HIV-1 clades. However, vaccines capable of stimulating the production of bNAbs remain a major challenge. Given that polyreactivity and autoreactivit...

journal_title：Journal of virology

authors： Gupta S,Clark ES,Termini JM,Boucher J,Kanagavelu S,LeBranche CC,Abraham S,Montefiori DC,Khan WN,Stone GW

更新日期：2015-04-01 00:00:00

abstract：:Recently, we demonstrated that inverted repeat sequences inserted into first-generation adenovirus (Ad) vector genomes mediate precise genomic rearrangements resulting in vector genomes devoid of all viral genes that are efficiently packaged into functional Ad capsids. As a specific application of this finding, we gen...

journal_title：Journal of virology

authors： Lieber A,Steinwaerder DS,Carlson CA,Kay MA

更新日期：1999-11-01 00:00:00

abstract：:Ultrastructure was correlated with growth kinetics of bdellophage VL-1 infecting host-dependent ("parasitic") Bdellovibrio bacteriovorus 109J in its Escherichia coli B host (the three-membered system), as well as in the host-independent ("saprophytic") derivative of the Bdellovibrio. Electron microscope observations s...

journal_title：Journal of virology

authors： Kessel M,Varon M

更新日期：1973-12-01 00:00:00

abstract：:The current therapy for hepatitis B and C is based on systemic administration of recombinant human alpha interferon (r-hIFN-alpha). However, systemic delivery of r-hIFN-alpha is associated with severe side effects, but more importantly, it is effective in only a small percentage of patients. In an effort to maximize I...

journal_title：Journal of virology

authors： Aurisicchio L,Delmastro P,Salucci V,Paz OG,Rovere P,Ciliberto G,La Monica N,Palombo F

更新日期：2000-05-01 00:00:00

abstract：UNLABELLED:Avian metapneumovirus (aMPV), also known as avian pneumovirus or turkey rhinotracheitis virus, is the causative agent of turkey rhinotracheitis and is associated with swollen head syndrome in chickens. Since its discovery in the 1970s, aMPV has been recognized as an economically important pathogen in the pou...

journal_title：Journal of virology

authors： Sun J,Wei Y,Rauf A,Zhang Y,Ma Y,Zhang X,Shilo K,Yu Q,Saif YM,Lu X,Yu L,Li J

更新日期：2014-11-01 00:00:00

abstract：UNLABELLED:In Kaposi's sarcoma-associated herpesvirus (KSHV), poly(ADP-ribose) polymerase 1 (PARP-1) acts as an inhibitor of lytic replication. Here, we demonstrate that KSHV downregulated PARP-1 upon reactivation. The viral processivity factor of KSHV (PF-8) interacted with PARP-1 and was sufficient to degrade PARP-1 ...

journal_title：Journal of virology

authors： Chung WC,Park JH,Kang HR,Song MJ

更新日期：2015-09-01 00:00:00

abstract：:Transduction of the liver with single-stranded adeno-associated virus serotype 2 (AAV2) vectors is inefficient; less than 10% of hepatocytes are permissive for stable transduction, and transgene expression is characterized by a lag phase of up to 6 weeks. AAV2-based vector genomes packaged inside AAV6 or AAV8 capsids ...

journal_title：Journal of virology

authors： Thomas CE,Storm TA,Huang Z,Kay MA

更新日期：2004-03-01 00:00:00

abstract：:Replication by many positive-strand RNA viruses includes genomic RNA amplification and subgenomic mRNA (sgRNA) transcription. For brome mosaic virus (BMV), both processes occur in virus-induced, membrane-associated compartments, require BMV replication factors 1a and 2a, and use negative-strand RNA3 as a template for ...

journal_title：Journal of virology

authors： Grdzelishvili VZ,Garcia-Ruiz H,Watanabe T,Ahlquist P

更新日期：2005-02-01 00:00:00

abstract：:Nuclei of cells infected with Moloney murine leukemia virus (MoMuLV) were examined for the presence of gag proteins. This analysis was performed in conjunction with other studies suggesting a possible role for gag proteins in regulating nuclear events relating to processing and/or transport of viral genomic RNA. We de...

journal_title：Journal of virology

authors： Nash MA,Meyer MK,Decker GL,Arlinghaus RB

更新日期：1993-03-01 00:00:00

abstract：:The 2009 pandemic influenza virus (pdm/09) has been frequently introduced to pigs and has reassorted with other swine viruses. Recently, H3N2 reassortants with pdm/09-like internal genes were isolated in Guangxi and Hong Kong, China. Genetic and epidemiological analyses suggest that these viruses have circulated in sw...

journal_title：Journal of virology

authors： Fan X,Zhu H,Zhou B,Smith DK,Chen X,Lam TT,Poon LL,Peiris M,Guan Y

更新日期：2012-02-01 00:00:00

abstract：:Extracts of competent cells of Bacillus subtilis exhibited nuclease activity on radioactively labeled cell deoxyribonucleic acid (DNA). The activity was not decreased when Mg was omitted from the reaction mixture but was decreased to zero by addition of ethylenediaminetetraacetic acid. Of the other metals tested, only...

journal_title：Journal of virology

authors： Epstein HT

更新日期：1971-06-01 00:00:00

abstract：:Cell fractionation and protein electrophoresis were used to study the intracellular sites of synthesis and intermediate structures in the assembly of the virion proteins of vesicular stomatitis virus. Each of the three major virion proteins assembled into virions through a separable pathway. The nucleocapsid (N) prote...

journal_title：Journal of virology

authors： Knipe DM,Baltimore D,Lodish HF

更新日期：1977-03-01 00:00:00

abstract：:trans activation of the human immunodeficiency virus type 1 long terminal repeat requires that the viral trans activator Tat interact with the trans-acting responsive region (TAR) RNA. Although the N-terminal 47 amino acids represent an independent activation domain that functions via heterologous nucleic acid-binding...

journal_title：Journal of virology

authors： Luo Y,Peterlin BM

更新日期：1993-06-01 00:00:00

abstract：:We located a region of interstrain size variability in a short segment in an area at the right-hand end of the long unique sequence of the varicella-zoster viral genome. Varicella-zoster virus strains isolated in a district of Japan were classified into three groups on the basis of the size of this segment. Sequence c...

journal_title：Journal of virology

authors： Hondo R,Yogo Y

更新日期：1988-08-01 00:00:00

abstract：:Induction of the resident prophage did not permit restricted phage T1 to replicate freely in P1-lysogenic hosts. A few induced cells did become infectible. ...

journal_title：Journal of virology

authors： Christensen JR,Werner ER

更新日期：1969-04-01 00:00:00

abstract：:The alphaherpesvirus proteins UL31 and UL34 and their homologues in other herpesvirus subfamilies cooperate at the nuclear membrane in the export of nascent herpesvirus capsids. We studied the respective betaherpesvirus proteins M53 and M50 in mouse cytomegalovirus (MCMV). Recently, we established a random approach to...

journal_title：Journal of virology

authors： Popa M,Ruzsics Z,Lötzerich M,Dölken L,Buser C,Walther P,Koszinowski UH

更新日期：2010-09-01 00:00:00

abstract：:Virus-like particles were purified from stools of patients in an epidemic of hepatitis A in Germany. When reference MS-1 chimpanzee pre-inoculation and convalescent sera were used, the close serological relationship of the purified particles to well-known isolates of hepatitis A could be established. On the other hand...

journal_title：Journal of virology

authors： Siegl G,Frösner GG

更新日期：1978-04-01 00:00:00

abstract：:The product of the human cytomegalovirus (HCMV) UL71 gene is conserved throughout the herpesvirus family. During HCMV infection, protein pUL71 is required for efficient virion egress and is involved in the final steps of secondary envelopment leading to infectious viral particles. We found strong indications for oligo...

journal_title：Journal of virology

authors： Meissner CS,Suffner S,Schauflinger M,von Einem J,Bogner E

更新日期：2012-03-01 00:00:00