Serum leptin and C-reactive protein levels in the physiological spontaneous menstrual cycle in reproductive age women.

abstract：:This study compared plasma concentrations of adrenocorticotropin (ACTH) and cortisol in young men (N = 10, mean age 24.4 years), young women (N = 10, mean age 25.4 years), old men (N = 8, mean age 81.6 years) and old women (N = 8, mean age 83.5 years) under basal resting conditions and after stimulation with either hu...

journal_title：European journal of endocrinology

authors： Born J,Ditschuneit I,Schreiber M,Dodt C,Fehm HL

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Somatostatin analogs (SA) are the cornerstone in the medical treatment of acromegaly, used as either primary or adjunctive therapy. In particular, SA are effective in inducing the biochemical remission of the disease and tumor shrinkage, although only few cases of complete disappearance of the pituitary tumo...

journal_title：European journal of endocrinology

authors： Auriemma RS,Galdiero M,Grasso LF,Vitale P,Cozzolino A,Lombardi G,Colao A,Pivonello R

更新日期：2010-05-01 00:00:00

abstract：:Objective Chronic hypoparathyroidism and its treatment may lead to symptoms and complications affecting quality of life. We determined complications in chronic hypoparathyroid patients. Design Retrospective cross-sectional study of patients with chronic hypoparathyroidism treated with active vitamin D supplements in a...

journal_title：European journal of endocrinology

authors： David K,Moyson C,Vanderschueren D,Decallonne B

更新日期：2019-01-01 00:00:00

abstract：Background:If biochemical control of acromegaly is not achieved by operation and medication, radiotherapy may be indicated. Objective:To describe fractionated radiotherapy (FRT) and stereotactic radiosurgery (SRS) regarding excess of IGF-1 and pituitary function. Design and methods:A retrospective analysis of 352 pat...

journal_title：European journal of endocrinology

authors： Knappe UJ,Petroff D,Quinkler M,Schmid SM,Schöfl C,Schopohl J,Stieg MR,Tönjes A,participants of the German Acromegaly Registry.

更新日期：2020-03-01 00:00:00

abstract：Background:Hypophosphataemic rickets (HR) comprise a clinically and genetically heterogeneous group of conditions, defined by renal-tubular phosphate wasting and consecutive loss of bone mineralisation. X-linked hypophosphataemia (XLH) is the most common form, caused by inactivating dominant mutations in PHEX, a gene e...

journal_title：European journal of endocrinology

authors： Thiele S,Werner R,Stubbe A,Hiort O,Hoeppner W

更新日期：2020-11-01 00:00:00

abstract：:Endogenous pathologic hypercortisolism, or Cushing's syndrome, is associated with poor quality of life, morbidity, and increased mortality. Early diagnosis may mitigate against this natural history of the disorder. The clinical presentation of Cushing's syndrome varies, in part related to the extent and duration of co...

journal_title：European journal of endocrinology

authors： Nieman LK

更新日期：2015-10-01 00:00:00

abstract：:Giant prolactinomas are rare tumours, representing only 2-3% of all prolactin (PRL)-secreting tumours and raising special diagnostic and therapeutic challenges. Based on several considerations developed in this review, their definition should be restricted to pituitary adenomas with a diameter of 40  mm or more, signi...

journal_title：European journal of endocrinology

authors： Maiter D,Delgrange E

更新日期：2014-06-01 00:00:00

abstract：:Growth hormone (GH) is used by athletes like bodybuilders to increase muscle strength and weight gain. On the other hand, chronic hypersecretion of GH in active acromegaly may result in outwardly hypertrophied but functionally weaker muscles. As a model for studying long-term effects of GH on muscle strength, we analy...

journal_title：European journal of endocrinology

authors： Wolf E,Wanke R,Schenck E,Hermanns W,Brem G

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:A sex determining gene(s) has been mapped to a approximately 700 kb region distal to the exons of DMRT1 on 9p. The aim of this study was to examine gonadal developmental status in XX patients hemizygous for the 9p sex determining region. DESIGN:Clinical and molecular studies were performed in an 8-year-old g...

journal_title：European journal of endocrinology

authors： Ogata T,Muroya K,Ohashi H,Mochizuki H,Hasegawa T,Kaji M

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:Polycystic ovarian syndrome (PCOS) is associated with skeletal muscle insulin resistance (IR), which has been linked to decreased mitochondrial function. We measured mitochondrial respiration in lean and obese women with and without PCOS using high-resolution respirometry. METHODS:Hyperinsulinemic-euglycemic...

journal_title：European journal of endocrinology

authors： Rabøl R,Svendsen PF,Skovbro M,Boushel R,Schjerling P,Nilas L,Madsbad S,Dela F

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:Mutations in HESX1 represent a rare cause of GH deficiency (GHD) associated with a broad spectrum of other anomalies. We searched for causative mutations in a cohort of 244 Italian patients affected by combined and isolated GHD (IGHD). METHODS:The HESX1 gene-coding region and exon-intron boundaries were scre...

journal_title：European journal of endocrinology

authors： Vivenza D,Godi M,Faienza MF,Mellone S,Moia S,Rapa A,Petri A,Bellone S,Riccomagno S,Cavallo L,Giordano M,Bona G

更新日期：2011-05-01 00:00:00

abstract：:Little is known about patients with malignant digestive neuroendocrine tumours (MD-NETs). Although their incidence is increasing, MD-NETs remain a rare cancer, representing 1% of digestive cancers. Most MD-NETs are well-differentiated. MD-NET poorly differentiated carcinomas account for 20% of cases on average. Anatom...

journal_title：European journal of endocrinology

authors： Lepage C,Bouvier AM,Faivre J

更新日期：2013-03-15 00:00:00

abstract：OBJECTIVE:The antagonism of Agouti protein (AP) and Agouti-related protein on melanocortin receptors suggests an inhibitory role in the regulation of steroidogenesis. However, we have previously demonstrated that ectopic AP overexpression increased restraint-induced corticosterone release and adrenal reactivity to ACTH...

journal_title：European journal of endocrinology

authors： Shevchenko AY,Bazhan NM,Makarova EN,Yakovleva TV,Karkaeva NR

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:We have studied the effect of tryptophan on cellular [(125)I]tri-iodothyronine (T3) uptake by mouse thymocytes. MATERIALS AND METHODS:Mouse thymocytes (20 x 10(6 )cells/ml) were suspended in Krebs-Ringer solution buffered by Tris-HCl and incubation (23 degrees C at pH7.45+/-0.6), in the presence or absence o...

journal_title：European journal of endocrinology

authors： Centanni M,Canettieri G,Viceconti N,Sibilla R,Bei A,Andreoli M

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:To compare clinical and humoral parameters before and after surgery in patients with incidental adrenocortical adenomas. DESIGN:Six patients with subclinical Cushing's syndrome and nine with non-functioning adenomas were investigated before and 12 Months after removal of the mass. METHODS:Anthropometric (bo...

journal_title：European journal of endocrinology

authors： Bernini G,Moretti A,Iacconi P,Miccoli P,Nami R,Lucani B,Salvetti A

更新日期：2003-02-01 00:00:00

abstract：Background/objective:Data on metabolic impairments in Cushing's syndrome and GH deficiency all suggest that the relationship between cortisol and GH/IGF-I axis in obesity may have a role in the related diseases. However, studies focusing only on one of these hormones are often controversial in paediatrics. We aimed to ...

journal_title：European journal of endocrinology

authors： Ricotti R,Solito A,Mariotti Zani E,Caputo M,Genoni G,Barone-Adesi F,Mancioppi V,Agosti E,Aimaretti G,Bellone S,Prodam F

更新日期：2020-03-01 00:00:00

abstract：DESIGN:The aim of this study was to determine the association between aging and adiponectin level from the aspect of the influence of renal function and sex hormones in humans. METHODS:Serum adiponectin and blood urea nitrogen (BUN) levels were measured in 964 subjects (372 males) aged 60.3+/-12.5 years. Testosterone ...

journal_title：European journal of endocrinology

authors： Isobe T,Saitoh S,Takagi S,Takeuchi H,Chiba Y,Katoh N,Shimamoto K

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:In males, the pubertal increase in sex hormone production has been associated with proatherogenic changes in lipid and carbohydrate metabolism. Aromatase inhibitors, a novel treatment modality for some growth disorders, may significantly influence these risk factors for cardiovascular disease by suppressing o...

journal_title：European journal of endocrinology

authors： Hero M,Ankarberg-Lindgren C,Taskinen MR,Dunkel L

更新日期：2006-09-01 00:00:00

abstract：CONTEXT AND OBJECTIVE:Arterial stimulation and venous sampling (ASVS) is an important technique for localizing insulinoma. The principle behind ASVS is that insulin secretion is promoted from insulinoma cells by the injection of calcium into the insulinoma-feeding artery. However, the mechanism for ASVS-induced insulin...

journal_title：European journal of endocrinology

authors： Ono Y,Oda N,Ishihara S,Shimomura A,Hayakawa N,Suzuki A,Horiguchi A,Senda T,Miyakawa S,Itoh M

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine the frequency and characteristics of severe GH deficiency (sGHD) in patients after treatment of acromegaly by surgery alone. DESIGN AND METHODS:One hundred and eighty-six patients fulfilling the criteria for cure of acromegaly were examined by GH-releasing peptide-2 sti...

journal_title：European journal of endocrinology

authors： Yamada S,Fukuhara N,Nishioka H,Takeshita A,Suzuki H,Miyakawa M,Takeuchi Y

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:KLF7 encodes Krüppel-like factor (KLF) 7, a member of the KLF family of transcription factors, initially shown to play important roles in cellular development and differentiation, and reported to be specifically involved in adipogenesis. Several single nucleotide polymorphisms (SNPs) have been identified in K...

journal_title：European journal of endocrinology

authors： Zobel DP,Andreasen CH,Burgdorf KS,Andersson EA,Sandbaek A,Lauritzen T,Borch-Johnsen K,Jørgensen T,Maeda S,Nakamura Y,Eiberg H,Pedersen O,Hansen T

更新日期：2009-04-01 00:00:00

abstract：:Kidney dysfunction has been observed in aged humans and rats, the primary cause of which may reside in the kidney itself or in the hypothalamus. The latter possibility is suggested by the increased release of AVP in response to salt infusion in humans. The effect of age on the relationship between plasma osmolality an...

journal_title：European journal of endocrinology

authors： Terwel D,Jolles J

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Some cases of apparently idiopathic GH deficiency (GHD) may be caused by pituitary autoimmunity. OBJECTIVE:To study the variations in pituitary function and antipituitary antibodies (APA) from childhood to transition age in patients with apparently idiopathic GHD. DESIGN:We conducted a longitudinal study. ...

journal_title：European journal of endocrinology

authors： De Bellis A,Bellastella G,Maiorino MI,Aitella E,Lucci E,Cozzolino D,Bellastella A,Bizzarro A,Giugliano D,Esposito K,Italian Autoimmune Hypophysitis Network Group.

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To establish an Inuit body mass index (BMI) norm from a healthy, not malnourished, pure Inuit population and to investigate the development of overweight in the Inuit in Greenland. DESIGN:Longitudinal study with 35 years follow-up on overweight among Inuit in Greenland. METHODS:The heights and weights of 97...

journal_title：European journal of endocrinology

authors： Andersen S,Mulvad G,Pedersen HS,Laurberg P

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVES:Women with polycystic ovary syndrome (PCOS) frequently suffer from metabolic disturbances, in particular from insulin resistance. Accumulating evidence suggests that vitamin D deficiency may contribute to the development of the metabolic syndrome (MS). Hence, the aim of our study was to investigate the assoc...

journal_title：European journal of endocrinology

authors： Wehr E,Pilz S,Schweighofer N,Giuliani A,Kopera D,Pieber TR,Obermayer-Pietsch B

更新日期：2009-10-01 00:00:00

abstract：AIMS:Reported cure rates following trans-sphenoidal surgery for microprolactinoma are variable and recurrence rates in some series are high. We wished to examine the cure rate of trans-sphenoidal surgery for microprolactinoma, and to assess the long-term complications and recurrence rate. DESIGN:A retrospective review...

journal_title：European journal of endocrinology

authors： Turner HE,Adams CB,Wass JA

更新日期：1999-01-01 00:00:00

abstract：:Here we describe the case of a 41-year-old woman with a history of Cushing disease who had previously undergone unsuccessful neurosurgery, followed by stereotactic radiosurgery. More than 4 years after this treatment, she presented severe visual impairment, which started in the left eye and was documented by neuro-oph...

journal_title：European journal of endocrinology

authors： Boschetti M,De Lucchi M,Giusti M,Spena C,Corallo G,Goglia U,Ceresola E,Resmini E,Vera L,Minuto F,Ferone D

更新日期：2006-06-01 00:00:00

abstract：:The episodicity of 24 h GH release was studied in 18 patients with active acromegaly, 12 patients 7-10 days after pituitary surgery, 14 patients long after operation (3-17 years), and 21 healthy gender- and age-matched control subjects, using a recently introduced scale- and model-independent regularity statistic, app...

journal_title：European journal of endocrinology

authors： van den Berg G,Pincus SM,Frölich M,Veldhuis JD,Roelfsema F

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVE:Adult height deficit seen in Turner syndrome (TS) originates, in part, from growth retardation in utero and throughout the first 3 years of life. Earlier diagnosis enables earlier therapeutic intervention, such as with recombinant human GH (r-hGH), which may help to prevent growth retardation. In this open-la...

journal_title：European journal of endocrinology

authors： Linglart A,Cabrol S,Berlier P,Stuckens C,Wagner K,de Kerdanet M,Limoni C,Carel JC,Chaussain JL,French Collaborative Young Turner Study Group.

更新日期：2011-06-01 00:00:00

abstract：:Pituitary adenomas occur in a familial setting in multiple endocrine neoplasia type 1 (MEN1) and Carney's complex (CNC), which occur due to mutations in the genes MEN1 and PRKAR1A respectively. Isolated familial somatotropinoma (IFS) is also a well-described clinical syndrome related only to patients with acrogigantis...

journal_title：European journal of endocrinology

authors： Beckers A,Daly AF

更新日期：2007-10-01 00:00:00